LOCUS       NM_001198562             882 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus nascent polypeptide associated complex subunit
            alpha (Naca), transcript variant 1, mRNA.
ACCESSION   NM_001198562
VERSION     NM_001198562.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 882)
  AUTHORS   Berkholz,J., Zakrzewicz,A. and Munz,B.
  TITLE     skNAC depletion stimulates myoblast migration and perturbs
            sarcomerogenesis by enhancing calpain 1 and 3 activity
  JOURNAL   Biochem J 453 (2), 303-310 (2013)
   PUBMED   23662692
REFERENCE   2  (bases 1 to 882)
  AUTHORS   Park,C.Y., Pierce,S.A., von Drehle,M., Ivey,K.N., Morgan,J.A.,
            Blau,H.M. and Srivastava,D.
  TITLE     skNAC, a Smyd1-interacting transcription factor, is involved in
            cardiac development and skeletal muscle growth and regeneration
  JOURNAL   Proc Natl Acad Sci U S A 107 (48), 20750-20755 (2010)
   PUBMED   21071677
REFERENCE   3  (bases 1 to 882)
  AUTHORS   Yotov,W.V., Moreau,A. and St-Arnaud,R.
  TITLE     The alpha chain of the nascent polypeptide-associated complex
            functions as a transcriptional coactivator
  JOURNAL   Mol Cell Biol 18 (3), 1303-1311 (1998)
   PUBMED   9488445
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Jan 18, 2018 this sequence version replaced NM_001198562.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ221678.1, FQ231879.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-99                JAXUCZ010000007.1  1054319-1054417
            100-171             JAXUCZ010000007.1  1055210-1055281
            172-257             JAXUCZ010000007.1  1064860-1064945
            258-335             JAXUCZ010000007.1  1065288-1065365
            336-482             JAXUCZ010000007.1  1065507-1065653
            483-611             JAXUCZ010000007.1  1065955-1066083
            612-734             JAXUCZ010000007.1  1066214-1066336
            735-882             JAXUCZ010000007.1  1066459-1066606
FEATURES             Location/Qualifiers
     source          1..882
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q11"
     gene            1..882
                     /gene="Naca"
                     /note="nascent polypeptide associated complex subunit
                     alpha"
                     /db_xref="GeneID:288770"
                     /db_xref="RGD:1308642"
     exon            1..99
                     /gene="Naca"
                     /inference="alignment:Splign:2.1.0"
     exon            100..171
                     /gene="Naca"
                     /inference="alignment:Splign:2.1.0"
     CDS             102..749
                     /gene="Naca"
                     /EC_number="5.3.99.3"
                     /note="isoform 1 is encoded by transcript variant 1;
                     nascent-polypeptide-associated complex alpha polypeptide;
                     nascent polypeptide-associated complex alpha subunit"
                     /codon_start=1
                     /product="nascent polypeptide-associated complex subunit
                     alpha isoform 1"
                     /protein_id="NP_001185491.1"
                     /db_xref="GeneID:288770"
                     /db_xref="RGD:1308642"
                     /translation="MPGEATETVPATEQELPQPQAETGSGTESDSDESVPELEEQDST
                     QTATQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNI
                     LFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTP
                     TVQEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSNDIVNAIMELTM"
     exon            172..257
                     /gene="Naca"
                     /inference="alignment:Splign:2.1.0"
     exon            258..335
                     /gene="Naca"
                     /inference="alignment:Splign:2.1.0"
     exon            336..482
                     /gene="Naca"
                     /inference="alignment:Splign:2.1.0"
     exon            483..611
                     /gene="Naca"
                     /inference="alignment:Splign:2.1.0"
     exon            612..734
                     /gene="Naca"
                     /inference="alignment:Splign:2.1.0"
     exon            735..882
                     /gene="Naca"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cccgccctct tggtgccccg cttccttctg caacaggcgt gggtcacggg ctcgctcgct
       61 ctctttccac cgccatcttg gttccgtgtt ctccgcacaa aatgcccggt gaagccacag
      121 aaaccgtccc tgctacagag caggagttgc cacagcctca ggctgagaca gggtcgggaa
      181 cagagtctga cagtgatgaa tcagtgccag aactcgagga acaggattcc acacagacag
      241 ccacacaaca ggcccagctg gcagccgcgg ctgagatcga tgaagaacct gttagtaaag
      301 ccaagcagag tcggagtgag aaaaaggcaa ggaaggccat gtccaaactg ggtcttcgac
      361 aggttacagg ggttacgaga gtcactatcc ggaaatctaa aaatatcctc tttgtcatca
      421 caaaaccgga tgtctacaag agcccagctt cagataccta catagtgttt ggggaggcca
      481 agattgagga cttgtcgcag caagcacagt tggcagctgc tgagaagttc aaagttcaag
      541 gagaggctgt ttccaacatt caggagaaca cgcagacgcc gactgtccaa gaggagagcg
      601 aagaagagga ggttgatgaa acgggtgtgg aagttaagga catagagttg gtcatgtcac
      661 aagcaaatgt gtcaagagca aaggctgtcc gagccctgaa aaacaacagt aacgatattg
      721 taaatgctat tatggaatta acaatgtaat tatctgacag caaggacacc ctcctccccc
      781 ttccccccct ttttggtgtt tgaaaagtgg aactacagct tggtttaaaa tttgtactgt
      841 ttctatcact aataaagtgt agcttcttgt tggatggact ca
//
