LOCUS       NM_001034939            1388 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Rattus norvegicus nucleic acid binding protein 2 (Nabp2),
            transcript variant 1, mRNA.
ACCESSION   NM_001034939 XM_343141
VERSION     NM_001034939.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1388)
  AUTHORS   Pandita,R.K., Chow,T.T., Udayakumar,D., Bain,A.L., Cubeddu,L.,
            Hunt,C.R., Shi,W., Horikoshi,N., Zhao,Y., Wright,W.E., Khanna,K.K.,
            Shay,J.W. and Pandita,T.K.
  TITLE     Single-strand DNA-binding protein SSB1 facilitates TERT recruitment
            to telomeres and maintains telomere G-overhangs
  JOURNAL   Cancer Res 75 (5), 858-869 (2015)
   PUBMED   25589350
REFERENCE   2  (bases 1 to 1388)
  AUTHORS   Gu,P., Deng,W., Lei,M. and Chang,S.
  TITLE     Single strand DNA binding proteins 1 and 2 protect newly replicated
            telomeres
  JOURNAL   Cell Res 23 (5), 705-719 (2013)
   PUBMED   23459151
REFERENCE   3  (bases 1 to 1388)
  AUTHORS   Li,Y., Bolderson,E., Kumar,R., Muniandy,P.A., Xue,Y., Richard,D.J.,
            Seidman,M., Pandita,T.K., Khanna,K.K. and Wang,W.
  TITLE     HSSB1 and hSSB2 form similar multiprotein complexes that
            participate in DNA damage response
  JOURNAL   J Biol Chem 284 (35), 23525-23531 (2009)
   PUBMED   19605351
REFERENCE   4  (bases 1 to 1388)
  AUTHORS   Huang,J., Gong,Z., Ghosal,G. and Chen,J.
  TITLE     SOSS complexes participate in the maintenance of genomic stability
  JOURNAL   Mol Cell 35 (3), 384-393 (2009)
   PUBMED   19683501
REFERENCE   5  (bases 1 to 1388)
  AUTHORS   Richard,D.J., Bolderson,E., Cubeddu,L., Wadsworth,R.I., Savage,K.,
            Sharma,G.G., Nicolette,M.L., Tsvetanov,S., McIlwraith,M.J.,
            Pandita,R.K., Takeda,S., Hay,R.T., Gautier,J., West,S.C.,
            Paull,T.T., Pandita,T.K., White,M.F. and Khanna,K.K.
  TITLE     Single-stranded DNA-binding protein hSSB1 is critical for genomic
            stability
  JOURNAL   Nature 453 (7195), 677-681 (2008)
   PUBMED   18449195
REFERENCE   6  (bases 1 to 1388)
  AUTHORS   Ahmed,F., Torrado,M., Zinovieva,R.D., Senatorov,V.V., Wistow,G. and
            Tomarev,S.I.
  TITLE     Gene expression profile of the rat eye iridocorneal angle: NEIBank
            expressed sequence tag analysis
  JOURNAL   Invest Ophthalmol Vis Sci 45 (9), 3081-3090 (2004)
   PUBMED   15326124
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC104710.1.
            
            On Oct 21, 2005 this sequence version replaced XM_343141.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and it encodes the longer protein (isoform 1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC104710.1, SRR8487226.155799.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06621351 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1388              BC104710.1         1-1388
FEATURES             Location/Qualifiers
     source          1..1388
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q11"
     gene            1..1388
                     /gene="Nabp2"
                     /gene_synonym="Obfc2b; RGD1308158"
                     /note="nucleic acid binding protein 2"
                     /db_xref="GeneID:362813"
                     /db_xref="RGD:1308158"
     exon            1..476
                     /gene="Nabp2"
                     /gene_synonym="Obfc2b; RGD1308158"
                     /inference="alignment:Splign:2.1.0"
     CDS             302..1033
                     /gene="Nabp2"
                     /gene_synonym="Obfc2b; RGD1308158"
                     /note="isoform 1 is encoded by transcript variant 1; SOSS
                     complex subunit B1; SOSS-B1; sensor of ssDNA subunit B1;
                     single-stranded DNA-binding protein 1; sensor of
                     single-strand DNA complex subunit B1;
                     oligonucleotide/oligosaccharide-binding fold-containing
                     protein 2B; oligonucleotide/oligosaccharide-binding fold
                     containing 2B"
                     /codon_start=1
                     /product="SOSS complex subunit B1 isoform 1"
                     /protein_id="NP_001030111.2"
                     /db_xref="GeneID:362813"
                     /db_xref="RGD:1308158"
                     /translation="MGRPSGSMGQRLQALNLHLPFPLPAGCHGSGSMTTETFVKDIKP
                     GLKNLNLIFIVLETGRVTKTKDGHEVRTCKVADKTGSINISVWDDVGNLIQPGDIIRL
                     TKGYASVFKGCLTLYTGRGGDLQKIGEFCMVYSEVPNFSEPNPEYNTQQASNKSVQND
                     SSPTAPQATTGPPAASPASESQNGNGLSTQPGPVGGPHPSHAPSHPPSTRITRSQPNH
                     TPSGPPGPSSSPVSNGKETRRSSKR"
     exon            477..615
                     /gene="Nabp2"
                     /gene_synonym="Obfc2b; RGD1308158"
                     /inference="alignment:Splign:2.1.0"
     exon            616..687
                     /gene="Nabp2"
                     /gene_synonym="Obfc2b; RGD1308158"
                     /inference="alignment:Splign:2.1.0"
     exon            688..769
                     /gene="Nabp2"
                     /gene_synonym="Obfc2b; RGD1308158"
                     /inference="alignment:Splign:2.1.0"
     exon            770..833
                     /gene="Nabp2"
                     /gene_synonym="Obfc2b; RGD1308158"
                     /inference="alignment:Splign:2.1.0"
     exon            834..1357
                     /gene="Nabp2"
                     /gene_synonym="Obfc2b; RGD1308158"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgcgaatcgg gtaggggatg gaccgagttc tgggtcgcgg ggacgagagt tcaggaagat
       61 ctgccgagtg aggttctgtt ccctggagct gcaccgggtt ccctacgagt ctccttcagc
      121 ctccccgctt cggagcgtga gactgaaggc atcctgacag agggccttcc atccccctaa
      181 gcatcttacc cagagatcta taagttctga tcttgaagta cgaggccccc agggaagttc
      241 gtttctaacc tcccagaagg gttagagggg gaccaaggct gccaaattcc cgcctgctgt
      301 gatgggtagg ccaagcggga gcatggggca gaggctccaa gccttgaatc ttcatctccc
      361 atttccgctt ccagcggggt gccacggctc gggaagcatg acgaccgaga ccttcgtgaa
      421 ggatatcaag cccgggctca agaatctgaa ccttatcttc attgtactgg agacaggtcg
      481 ggtgaccaag acaaaggatg ggcacgaggt tcggacttgt aaagtggcag acaaaacggg
      541 cagcatcaac atctcagtgt gggacgatgt gggcaaccta atccaacccg gggacattat
      601 ccgactcacc aaagggtacg cctcagtgtt caaaggttgt ctgacactat acactggccg
      661 tgggggcgat ctgcaaaaga ttggagaatt ctgcatggtt tattctgaag ttcctaattt
      721 cagcgagccc aatccagagt ataacaccca gcaggcatcc aacaaatcgg tgcagaatga
      781 cagcagccct actgccccac aagctaccac aggaccccct gccgcctctc cagcttccga
      841 gagccagaac gggaatggac tgagcaccca gccaggtcct gttggtggcc cccatccctc
      901 tcacgccccc tcacatcccc ccagcacccg aatcactcga agccagccca accacacgcc
      961 ttctggccct cctggcccct ccagcagccc tgtcagcaac ggcaaagaaa cccgcaggag
     1021 cagcaagaga tagcaagaga tgaggcttcc ttcctcctac cacagccacg acccaggtgt
     1081 ctcttcagag aagaagacag ttttccatta ggctgtagct ttgggattag agggtgaagt
     1141 agctgtgttt tagccactaa atttcgctgg aggggtggta agcagtggtc ttatccacct
     1201 caaactcacg ccctccttgt cctgctgatg ctgtctgtcc cctgggatcc aggtcctctg
     1261 cctgccctcc tttggaaaag acagtctgga ttttgtgtgg gatatgaggg tctaactgaa
     1321 atccctcttc ctaataaaca ttcccacttg ttctggaaaa aaaaaaaaaa aaaaaaaaaa
     1381 aaaaaaaa
//
