LOCUS       NM_001134874            3366 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus Ngfi-A binding protein 2 (Nab2), mRNA.
ACCESSION   NM_001134874 XM_001056620 XM_235224
VERSION     NM_001134874.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3366)
  AUTHORS   Killick,R., Ribe,E.M., Al-Shawi,R., Malik,B., Hooper,C.,
            Fernandes,C., Dobson,R., Nolan,P.M., Lourdusamy,A., Furney,S.,
            Lin,K., Breen,G., Wroe,R., To,A.W., Leroy,K., Causevic,M.,
            Usardi,A., Robinson,M., Noble,W., Williamson,R., Lunnon,K.,
            Kellie,S., Reynolds,C.H., Bazenet,C., Hodges,A., Brion,J.P.,
            Stephenson,J., Simons,J.P. and Lovestone,S.
  TITLE     Clusterin regulates beta-amyloid toxicity via Dickkopf-1-driven
            induction of the wnt-PCP-JNK pathway
  JOURNAL   Mol Psychiatry 19 (1), 88-98 (2014)
   PUBMED   23164821
REFERENCE   2  (bases 1 to 3366)
  AUTHORS   Le,N., Nagarajan,R., Wang,J.Y., Svaren,J., LaPash,C., Araki,T.,
            Schmidt,R.E. and Milbrandt,J.
  TITLE     Nab proteins are essential for peripheral nervous system
            myelination
  JOURNAL   Nat Neurosci 8 (7), 932-940 (2005)
   PUBMED   16136673
REFERENCE   3  (bases 1 to 3366)
  AUTHORS   Jouvert,P., Dietrich,J.B., Aunis,D. and Zwiller,J.
  TITLE     Differential rat brain expression of EGR proteins and of the
            transcriptional corepressor NAB in response to acute or chronic
            cocaine administration
  JOURNAL   Neuromolecular Med 1 (2), 137-151 (2002)
   PUBMED   12025859
  REMARK    GeneRIF: nab2 protein--a transcripitonal corepresor expressed in
            rat brain in ersponse to cocaine administrtion
REFERENCE   4  (bases 1 to 3366)
  AUTHORS   Svaren,J., Sevetson,B.R., Apel,E.D., Zimonjic,D.B., Popescu,N.C.
            and Milbrandt,J.
  TITLE     NAB2, a corepressor of NGFI-A (Egr-1) and Krox20, is induced by
            proliferative and differentiative stimuli
  JOURNAL   Mol Cell Biol 16 (7), 3545-3553 (1996)
   PUBMED   8668170
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On or before Sep 13, 2008 this sequence version replaced
            XM_001056620.1, XM_235224.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.39495.1,
                                           SRR26643285.27802.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-293               JAXUCZ010000007.1  65388963-65389255   c
            294-1167            JAXUCZ010000007.1  65387033-65387906   c
            1168-1301           JAXUCZ010000007.1  65386539-65386672   c
            1302-1353           JAXUCZ010000007.1  65386124-65386175   c
            1354-1486           JAXUCZ010000007.1  65385906-65386038   c
            1487-1678           JAXUCZ010000007.1  65385506-65385697   c
            1679-3366           JAXUCZ010000007.1  65382863-65384550   c
FEATURES             Location/Qualifiers
     source          1..3366
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q22"
     gene            1..3366
                     /gene="Nab2"
                     /note="Ngfi-A binding protein 2"
                     /db_xref="GeneID:314910"
                     /db_xref="RGD:1311712"
     exon            1..293
                     /gene="Nab2"
                     /inference="alignment:Splign:2.1.0"
     CDS             211..1788
                     /gene="Nab2"
                     /codon_start=1
                     /product="NGFI-A-binding protein 2"
                     /protein_id="NP_001128346.1"
                     /db_xref="GeneID:314910"
                     /db_xref="RGD:1311712"
                     /translation="MHRAPSPTAEQPPGRADNTRRTPQPRVKASASTMALPRTLGELQ
                     LYRVLQRANLLSYYETFIQQGGDDVQQLCEAGEEEFLEIMALVGMATKPLHVRRLQKA
                     LREWATNPGLFSQPVPAVPVSSIPLFKISETAGTRKGSMSNGHGSPGEKAGSARSFSP
                     KSPLELGEKLSPLPGGPGAGDPRIWPGQSTPESDVGAGGEEEAGSPPFSPPAGGGVPE
                     GTGAGGVAAGGTGGGPDRLEPEMVRMVVESVERIFRSFPRGDTGEITSLLKLNKKLAR
                     SVGHIFEMDDNDSQKEEEIRKYSIIYGRLDSKRREGKQLSLHELTINEAAAQFCMRDN
                     TLLLRRVELFSLSRQVARESTYLSSLKGSRLHSEELGGPPLKKLKQEVGEQSHTEIQQ
                     PPPGPEPYAPPYRPSLEEDSASLSGESLDGHLQAVGSCPRLTPPPADLPLALPAHGLW
                     SRHILQQTLMDEGLRLARLVSHDRVGRLSPCVPAKPPLAEFEEGLLDRCPAPGPHPAL
                     VEGRRSSVKVEAEASRQ"
     exon            294..1167
                     /gene="Nab2"
                     /inference="alignment:Splign:2.1.0"
     exon            1168..1301
                     /gene="Nab2"
                     /inference="alignment:Splign:2.1.0"
     exon            1302..1353
                     /gene="Nab2"
                     /inference="alignment:Splign:2.1.0"
     exon            1354..1486
                     /gene="Nab2"
                     /inference="alignment:Splign:2.1.0"
     exon            1487..1678
                     /gene="Nab2"
                     /inference="alignment:Splign:2.1.0"
     exon            1679..3366
                     /gene="Nab2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggggaggagg cgcggagagg cggcaagctc agccggggag gtgggggcag aggcacagac
       61 agaggcgcgg aggctccgag agagaagacg tggagggagg gacggagcca ggacagcggt
      121 ggacccgggc cgcgcgcgct ccaggcaaag agcagcgcgc agcaggcgcc gggcaccgag
      181 acgggaggca cgggtgatct ctggccgtcc atgcacagag cgccctctcc cacagcggag
      241 cagccacctg gcagagcgga taacacccgc cggaccccac aacccagagt caaggcaagt
      301 gcctcaacca tggcactgcc tcgaacactg ggtgagctgc agctgtaccg ggtcctgcag
      361 cgtgccaacc ttctttctta ctacgagacc ttcatccagc agggagggga tgatgtacag
      421 cagctgtgtg aggcgggcga ggaggagttc ctggaaatca tggcacttgt gggcatggcc
      481 accaaaccac tccatgtccg acgtctacag aaggctctga gagaatgggc caccaaccca
      541 gggctcttca gccaaccagt gcctgctgtg cctgtctcca gcatcccact tttcaagatc
      601 tctgagacag ctggtacccg gaaagggagc atgagcaatg ggcatggcag cccaggagaa
      661 aaggcgggca gtgctcgaag ctttagcccc aagagtcccc ttgaacttgg agagaagcta
      721 tcaccacttc ctggaggacc tggtgcaggg gatccccgga tctggccagg ccagagcact
      781 ccagaatctg atgttggagc aggaggagaa gaggaggccg ggtctccccc tttctccccc
      841 cctgcagggg gaggagtccc tgaggggact ggggctgggg gggtggctgc aggtggcaca
      901 gggggtggtc cagaccgcct ggaaccagag atggtgcgaa tggtggtaga gagtgtggag
      961 aggatcttcc ggagtttccc caggggtgac actggagaga tcacatccct gttgaagctg
     1021 aataagaagc tggcacggag tgtggggcac atctttgaga tggatgataa cgacagccag
     1081 aaagaagagg agatccgaaa atatagcatc atctatggcc gcttggattc caaacggcgt
     1141 gagggcaaac agcttagctt gcacgagttg accatcaatg aggctgctgc ccagttctgc
     1201 atgagggaca acaccctttt acttcgaagg gtagaacttt tctcactgtc ccgccaagta
     1261 gcccgagaga gcacctatct ttcttccttg aagggatcca ggcttcactc tgaagaattg
     1321 ggaggtccac cactgaagaa actgaaacaa gaggttggag aacagagtca tactgaaatc
     1381 cagcagcctc ctccaggccc tgagccctat gcacccccat accgccccag cctcgaggag
     1441 gacagcgcca gtctgtctgg ggagagccta gatggtcact tgcaggctgt ggggtcgtgc
     1501 ccaaggctga cgccgccccc tgctgacctg cccctggcat tgccagcgca tgggctatgg
     1561 agccgccaca tcttgcagca gacactgatg gatgaggggc tgcggctcgc ccgcctcgtc
     1621 tcccatgatc gtgtgggccg cctcagcccc tgtgtgcctg cgaagccgcc tctcgcagaa
     1681 ttcgaggaag ggttgctgga tcgctgtcct gccccaggac ctcatcctgc tctggtggag
     1741 ggtcgcagga gcagcgtcaa agtggaggca gaagccagca ggcagtgaaa gtgggggagt
     1801 ctcagaccca ggacccagac ttctggctca cttaagaccc cccacattct ccatccttgc
     1861 actcggcact accctagaag gatccttctg ctgccctctg cctcccatcc gctccatggg
     1921 cacaggacta tggggcttca agcaataaca aacaggggcc tagccagagg actcaagggt
     1981 gcaaggtgtg ccctcacccg gctcaggggc gtggactttg cctccagcct gctggggctc
     2041 tcctttctct cataccacac acacccattc tccaggtggc cagcagtggt gtgagcggct
     2101 gaactactct gcttggaaga gaagaacttc cccgggaagg cctagcagct taaatggaac
     2161 cgtttgctct gagactgggg gcttgggaaa actgggtctc cctcccccat cctcattttt
     2221 tgtgcttcta gtttgtttct ttaatttaac aagtgctgca gttcgcccgc cccgttctca
     2281 tcacccctac cccccagcag tcctctctct cgaactgtgt gaggctgccc cgcagttccc
     2341 tctaccagcc ccttagaggc ctgggttgga ccctgagtct cctcagccgg caggactgca
     2401 gcacctgtcg aacacttagc gtgtctttct tttcagattg tgtacagtag attatttatt
     2461 ttgttatttt ggaataaaat ttattttatg gcttaggatc catggccctc ttccccaaag
     2521 tgagggaaaa aggacagggt gagagtcggg ggggggggga gctggcagtg gacataaaaa
     2581 taggagagac agcagttgag ggccccaaca cccagggagt ttacacaatg aggtctgcac
     2641 ccctactcaa ccctcaggct ctaggaaagc tggaagcatg gactcaccaa ggctatcact
     2701 ggatgcatgt tacagccaca tagttactcc ccaaatgata ctgggtcact gtcttgtaca
     2761 atgtcttagc ctttcagata catgaggtca catgggcaaa agcagataca tgttctgtgt
     2821 ggtcatacag tgatgtgtga cgtctatagg tttaacatgt cttggggtaa acattggcac
     2881 ggctacacac aaacttagct cttacaatgc acaggctcaa atgtcacgag gcctcttttt
     2941 ggcaagactt tggagcttca gagaagtttt ggattttaat ctgggtaaaa cccataccag
     3001 taaccataca cctacgtttt cttttttttt tctcccagag tcacctgaac ccagctccaa
     3061 tccctaagcc tatgccctct gtctttggca cagtgtctat gttttgcgtg tgagtcccag
     3121 gccctggctc aacacagttc tggggtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt
     3181 tgtgcaggag cctgtatcac agagcccgaa tatcccccct catccctttg cacccggtgc
     3241 tggcaaaggg ggggcctggc gggataggaa ggacagagca cagcagttcc atatgccaca
     3301 cgttctccca gccagttctt ttctcttgac caaggaacag ctggagacgg aggcacctgc
     3361 atgagc
//
