LOCUS       NM_031759               2558 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus N-acetylated alpha-linked acidic dipeptidase-like
            1 (Naaladl1), mRNA.
ACCESSION   NM_031759 XM_346569
VERSION     NM_031759.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2558)
  AUTHORS   Tykvart,J., Barinka,C., Svoboda,M., Navratil,V., Soucek,R.,
            Hubalek,M., Hradilek,M., Sacha,P., Lubkowski,J. and Konvalinka,J.
  TITLE     Structural and biochemical characterization of a novel
            aminopeptidase from human intestine
  JOURNAL   J Biol Chem 290 (18), 11321-11336 (2015)
   PUBMED   25752612
REFERENCE   2  (bases 1 to 2558)
  AUTHORS   Shneider,B.L., Thevananther,S., Moyer,M.S., Walters,H.C.,
            Rinaldo,P., Devarajan,P., Sun,A.Q., Dawson,P.A. and
            Ananthanarayanan,M.
  TITLE     Cloning and characterization of a novel peptidase from rat and
            human ileum
  JOURNAL   J Biol Chem 272 (49), 31006-31015 (1997)
   PUBMED   9388249
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Nov 30, 2020 this sequence version replaced NM_031759.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF009921.1, SRR26643291.3917.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-215               JAXUCZ010000001.1  212829917-212830131
            216-388             JAXUCZ010000001.1  212830213-212830385
            389-510             JAXUCZ010000001.1  212830467-212830588
            511-633             JAXUCZ010000001.1  212830917-212831039
            634-917             JAXUCZ010000001.1  212835834-212836117
            918-1022            JAXUCZ010000001.1  212836199-212836303
            1023-1108           JAXUCZ010000001.1  212836796-212836881
            1109-1228           JAXUCZ010000001.1  212837012-212837131
            1229-1314           JAXUCZ010000001.1  212839672-212839757
            1315-1378           JAXUCZ010000001.1  212839865-212839928
            1379-1446           JAXUCZ010000001.1  212840011-212840078
            1447-1538           JAXUCZ010000001.1  212840195-212840286
            1539-1629           JAXUCZ010000001.1  212840376-212840466
            1630-1711           JAXUCZ010000001.1  212842123-212842204
            1712-1885           JAXUCZ010000001.1  212842286-212842459
            1886-1973           JAXUCZ010000001.1  212842536-212842623
            1974-2066           JAXUCZ010000001.1  212842722-212842814
            2067-2558           JAXUCZ010000001.1  212842983-212843474
FEATURES             Location/Qualifiers
     source          1..2558
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..2558
                     /gene="Naaladl1"
                     /gene_synonym="I100; Naaladasel"
                     /note="N-acetylated alpha-linked acidic dipeptidase-like
                     1"
                     /db_xref="GeneID:83568"
                     /db_xref="RGD:620987"
     exon            1..215
                     /gene="Naaladl1"
                     /gene_synonym="I100; Naaladasel"
                     /inference="alignment:Splign:2.1.0"
     CDS             16..2253
                     /gene="Naaladl1"
                     /gene_synonym="I100; Naaladasel"
                     /EC_number="3.4.17.21"
                     /note="N-acetylated-alpha-linked acidic dipeptidase-like
                     protein; ileal peptidase I100; NAALADase L; ileal
                     dipeptidylpeptidase; 100 kDa ileum brush border membrane
                     protein; N-acetylated alpha-linked acidic dipeptidase-like
                     (ileal peptidase I100)"
                     /codon_start=1
                     /product="aminopeptidase NAALADL1"
                     /protein_id="NP_113947.1"
                     /db_xref="GeneID:83568"
                     /db_xref="RGD:620987"
                     /translation="MHWAKILGVGIGAAALLGLGIILGHFAIPKATEPLASSVSDSQD
                     LDLAILDSVMGQLDASRIRENLRELSKEPHVATSARDEALVQLLLGRWKDSASGLDTA
                     KTYEYTVLLSFPSTEQPNSVEVVGPNGTVFHSFQPFEKNLTGEQAEPNVLQPYAAYAP
                     PGTPKGPLVYANRGSEDDFKKLEAEGINLKGTIALTRYGSVGRGAKAINAARHGVVGV
                     LVYTDPGDINDGKSLPNETFPNSWGLPPSGVERGSYYEYFGDPLTPYLPAHPVSFRLD
                     PHNISGFPPIPTQPIGFEDAKNLLCNLNGTSAPDSWQGALGCEYKLGPGFEPNGNFPA
                     GSEVKVSVYNRLELRNSSNVLGIIQGAVEPDRYVIYGNHRDSWVHGAVDPSSGTAVLL
                     EISRVLGTLLKKGTWRPRRSIIFASWGAEEFGLIGSTEFTEEFLSKLQERTVTYINVD
                     ISVFSNATLRAQGTPPVQSVIFSATKEISAPGSSGLSIYDNWIRYTNRSSPVYGLVPS
                     MGTLGAGSDYASFIHFLGITSMDLAYTYDRSKTSARIYPTYHTAFDTFDYVEKFLDPG
                     FSSHQAVARTAGSVLLRLSDSLFLPLNVSDYSETLQSFLQAAQENLGALLESHNISLG
                     PLVTAVEKFKAAAAALNQHILTLQKSSPDPLQVRMVNDQLMLLERAFLNPRAFPEERY
                     YSHVLWAPNTASVATFPGLANAYARAQEINSGAEAWAEVERQLSIAVMALEGAAATLQ
                     PVTDL"
     exon            216..388
                     /gene="Naaladl1"
                     /gene_synonym="I100; Naaladasel"
                     /inference="alignment:Splign:2.1.0"
     exon            389..510
                     /gene="Naaladl1"
                     /gene_synonym="I100; Naaladasel"
                     /inference="alignment:Splign:2.1.0"
     exon            511..633
                     /gene="Naaladl1"
                     /gene_synonym="I100; Naaladasel"
                     /inference="alignment:Splign:2.1.0"
     exon            634..917
                     /gene="Naaladl1"
                     /gene_synonym="I100; Naaladasel"
                     /inference="alignment:Splign:2.1.0"
     exon            918..1022
                     /gene="Naaladl1"
                     /gene_synonym="I100; Naaladasel"
                     /inference="alignment:Splign:2.1.0"
     exon            1023..1108
                     /gene="Naaladl1"
                     /gene_synonym="I100; Naaladasel"
                     /inference="alignment:Splign:2.1.0"
     exon            1109..1228
                     /gene="Naaladl1"
                     /gene_synonym="I100; Naaladasel"
                     /inference="alignment:Splign:2.1.0"
     exon            1229..1314
                     /gene="Naaladl1"
                     /gene_synonym="I100; Naaladasel"
                     /inference="alignment:Splign:2.1.0"
     exon            1315..1378
                     /gene="Naaladl1"
                     /gene_synonym="I100; Naaladasel"
                     /inference="alignment:Splign:2.1.0"
     exon            1379..1446
                     /gene="Naaladl1"
                     /gene_synonym="I100; Naaladasel"
                     /inference="alignment:Splign:2.1.0"
     exon            1447..1538
                     /gene="Naaladl1"
                     /gene_synonym="I100; Naaladasel"
                     /inference="alignment:Splign:2.1.0"
     exon            1539..1629
                     /gene="Naaladl1"
                     /gene_synonym="I100; Naaladasel"
                     /inference="alignment:Splign:2.1.0"
     exon            1630..1711
                     /gene="Naaladl1"
                     /gene_synonym="I100; Naaladasel"
                     /inference="alignment:Splign:2.1.0"
     exon            1712..1885
                     /gene="Naaladl1"
                     /gene_synonym="I100; Naaladasel"
                     /inference="alignment:Splign:2.1.0"
     exon            1886..1973
                     /gene="Naaladl1"
                     /gene_synonym="I100; Naaladasel"
                     /inference="alignment:Splign:2.1.0"
     exon            1974..2066
                     /gene="Naaladl1"
                     /gene_synonym="I100; Naaladasel"
                     /inference="alignment:Splign:2.1.0"
     exon            2067..2558
                     /gene="Naaladl1"
                     /gene_synonym="I100; Naaladasel"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggctgttacc acaggatgca ctgggcgaaa atactagggg tgggcatcgg ggcagccgcc
       61 ctcttggggc tggggatcat cctggggcac tttgccatcc ccaaagcaac tgaacctctg
      121 gcctccagtg tttcagactc ccaggacctg gacctggcga tccttgactc tgtaatggga
      181 caactagatg ctagtaggat ccgagagaac ctccgagaac tctccaagga accacatgtg
      241 gccaccagcg ctcgggatga ggccctggtg cagctgctgc tggggcgctg gaaggattcg
      301 gcgagtgggc tggacacagc caagacctat gagtacacgg tcctgctctc cttccccagc
      361 acagagcagc ctaacagcgt ggaagtcgtg ggccccaatg ggacggtctt ccactccttc
      421 caacccttcg agaagaatct gaccggggag caggcagagc ccaatgtgtt gcaaccttat
      481 gctgcctacg ctccccctgg gaccccaaag ggcccccttg tctatgccaa ccgaggctca
      541 gaagacgact tcaagaagtt agaggctgag ggcatcaacc ttaaaggcac catcgcactg
      601 actcgctacg ggagcgtggg gcgtggggcc aaggccatca atgctgccag gcacggagtt
      661 gttggagtgc tggtgtacac tgaccctggt gatatcaatg acgggaagag cttgcctaat
      721 gaaaccttcc ccaactcctg gggactgcct ccttctggtg tggagcgagg ctcctactat
      781 gagtattttg gggaccctct gactccctac cttccagccc accccgtatc tttccgcctg
      841 gatcctcata acatctcggg atttccccca attcccaccc agcctatcgg ctttgaggat
      901 gcgaaaaacc tgctctgtaa cctcaatgga acatccgccc ccgactcctg gcagggagca
      961 ctgggttgtg agtacaagct gggaccgggt ttcgagccaa acggaaactt cccggctggc
     1021 agtgaggtga aagtgagtgt ctacaacagg ctggagctga ggaactcctc caacgtcctg
     1081 ggcattatcc agggggcagt ggagcctgat cgatatgtga tctacggaaa ccaccgggac
     1141 agctgggtac atggggcagt ggaccccagc agtggcactg ctgtcctctt ggagatctct
     1201 cgagtcctgg ggaccttgct aaagaagggc acctggcggc cccgtagatc catcatattt
     1261 gccagctggg gagcagagga gttcgggctc atcggctcca cagaattcac agaggagttc
     1321 ctcagcaagc tgcaggagcg cacagtgacc tacatcaacg tggacatctc tgtgttctcc
     1381 aatgctaccc tccgggcaca ggggacaccc cctgtacaaa gcgtgatctt ctctgccacc
     1441 aaagagatca gtgcaccagg ctccagtggc ctcagtatct atgacaactg gatccgatat
     1501 actaaccgca gtagtccagt atatggactg gttcccagca tgggcacact gggtgcaggc
     1561 agcgactatg cctcattcat tcacttcctg ggcatcacct ccatggacct tgcctacacc
     1621 tatgaccgga gcaagacctc agccaggatc tacccaacct accacacagc gtttgacacg
     1681 tttgactatg tggagaagtt tctggaccct ggtttcagca gccaccaggc tgtggcccgg
     1741 actgctggga gtgtgctgct ccggctgagt gacagcctct tcctgcccct caatgtcagt
     1801 gactatagtg agacactaca gagtttccta caggctgctc aagagaacct tggcgccctg
     1861 ttagagagtc ataacatcag tctggggccc ttggtgaccg cagtggagaa gtttaaggca
     1921 gcagctgcag ccttgaacca acacatcttg acactgcaga agagcagccc tgatcctctg
     1981 caggtacgga tggtcaatga ccagctaatg ctcttggaac gggcattcct gaacccgagg
     2041 gctttcccag aggagcgata ctatagccac gtgctctggg cacccaacac agcctctgtt
     2101 gccacattcc caggtctggc caatgcttat gctagggccc aggaaatcaa ctccggagct
     2161 gaagcttggg ctgaagtaga gaggcagctt agcattgcag taatggccct ggagggcgca
     2221 gcagccaccc tgcaacctgt gactgacctc taaccctagc cctgtccctg gggccttttc
     2281 ttatcttgca cctcttgcac ctgtttctct gggttatgtc ccagtccttt ctgagaccag
     2341 gagtaggtac accaggaagc actctagagt ttctatagca acagctggga gtccctggag
     2401 ttaaggacac ctgctcatgg tagtgggtga aatctggggc caaagtaata tagaggctaa
     2461 ccccttgctc agcctgcttt cctgttcctc tcctctatct cctctcttaa ccctcaaata
     2521 aacaaagtct agacgttcct gtccttgttt gaaaatca
//
