LOCUS       NM_001106802            2993 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus N-acetylated alpha-linked acidic dipeptidase 2
            (Naalad2), mRNA.
ACCESSION   NM_001106802 XM_001069794 XM_001069840 XM_001072869 XM_235877
VERSION     NM_001106802.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2993)
  AUTHORS   Collard,F., Vertommen,D., Constantinescu,S., Buts,L. and Van
            Schaftingen,E.
  TITLE     Molecular identification of beta-citrylglutamate hydrolase as
            glutamate carboxypeptidase 3
  JOURNAL   J Biol Chem 286 (44), 38220-38230 (2011)
   PUBMED   21908619
REFERENCE   2  (bases 1 to 2993)
  AUTHORS   Bzdega,T., Crowe,S.L., Ramadan,E.R., Sciarretta,K.H.,
            Olszewski,R.T., Ojeifo,O.A., Rafalski,V.A., Wroblewska,B. and
            Neale,J.H.
  TITLE     The cloning and characterization of a second brain enzyme with NAAG
            peptidase activity
  JOURNAL   J Neurochem 89 (3), 627-635 (2004)
   PUBMED   15086519
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473993.2.
            
            [WARNING] On Aug 6, 2024 this sequence was replaced by
            NM_001106802.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_235877.4, XM_001072869.1, XM_001069794.1, XM_001069840.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA5756307, SAMEA5760383
                              [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2993
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q13"
     gene            1..2993
                     /gene="Naalad2"
                     /note="N-acetylated alpha-linked acidic dipeptidase 2"
                     /db_xref="GeneID:300384"
                     /db_xref="RGD:1305872"
     exon            1..61
                     /gene="Naalad2"
                     /inference="alignment:Splign:2.1.0"
     exon            62..189
                     /gene="Naalad2"
                     /inference="alignment:Splign:2.1.0"
     exon            190..310
                     /gene="Naalad2"
                     /inference="alignment:Splign:2.1.0"
     CDS             246..2582
                     /gene="Naalad2"
                     /EC_number="3.4.17.21"
                     /codon_start=1
                     /product="N-acetylated-alpha-linked acidic dipeptidase 2"
                     /protein_id="NP_001100272.1"
                     /db_xref="GeneID:300384"
                     /db_xref="RGD:1305872"
                     /translation="MDFQDSGCRCRKIGLQRCSYCRPQACSCSQRHSLTQKGMARPRQ
                     LRGLGMCITAVLASFIMGFTVGWFTKPLKETTTSSAYHQSIQQKLLSEMKAENIRSFL
                     RSFTKLPHLAGTEQNLLLAKKIQTQWKKFGLDSANLVHYDVLLSYPNETNANYVSIVD
                     EHGAEIFKTSYLEPPPDGYENVTNIVPPYNAFSAHGMPEGELVYVNYARTEDFFKLER
                     EMHINCTGKIVIARYGKIFRGNKVKNAMLAGAMGIILYSDPADYFAPGVQPYPKGWNL
                     PGAAAQRGNVLNLNGAGDPLTPGYPAKEYTFRLPVEEAVGIPNIPVHPIGYNDAERLL
                     RNLGGTAPPDQSWKGSLNVSYNIGPGFSGSEYSRKVRMHVHNINKITRIYNVIGTIRG
                     STEPDRYVILGGHRDSWVFGGIDPTTGTAVLQEIARSFGKLVNGGWKPRRTIIFASWD
                     AEEFGLLGSTEWAEENAKILQERSIAYINSDSAIEGNYTLRVDCTPLLHQLVYKVARE
                     ISSPDDGFESKSLYESWLEKDPSPENKERPRINKLGSGSDFEAYFQRLGIASGRARYT
                     KNKKTDKYSSYPVYHTIYETFELVQNFYDPTFKKQLSVAQLRGALVYELADCVVIPFN
                     IQDYAKALKNYAASIFNLSKKHDQQLRDHGVSFDPLFSAVKNFSEAASDFHRRLTQVD
                     LNNPTAVRIMNDQQMLLERAFIDPLGLPGRPFYRHIIFAPSSHNKYAGESFPGIYDAM
                     FDIENKADTHLAWAEVKKHISIAAFTIQAAAGTLTDVL"
     exon            311..441
                     /gene="Naalad2"
                     /inference="alignment:Splign:2.1.0"
     exon            442..553
                     /gene="Naalad2"
                     /inference="alignment:Splign:2.1.0"
     exon            554..740
                     /gene="Naalad2"
                     /inference="alignment:Splign:2.1.0"
     exon            741..842
                     /gene="Naalad2"
                     /inference="alignment:Splign:2.1.0"
     exon            843..968
                     /gene="Naalad2"
                     /inference="alignment:Splign:2.1.0"
     exon            969..1155
                     /gene="Naalad2"
                     /inference="alignment:Splign:2.1.0"
     exon            1156..1249
                     /gene="Naalad2"
                     /inference="alignment:Splign:2.1.0"
     exon            1250..1348
                     /gene="Naalad2"
                     /inference="alignment:Splign:2.1.0"
     exon            1349..1434
                     /gene="Naalad2"
                     /inference="alignment:Splign:2.1.0"
     exon            1435..1554
                     /gene="Naalad2"
                     /inference="alignment:Splign:2.1.0"
     exon            1555..1637
                     /gene="Naalad2"
                     /inference="alignment:Splign:2.1.0"
     exon            1638..1701
                     /gene="Naalad2"
                     /inference="alignment:Splign:2.1.0"
     exon            1702..1769
                     /gene="Naalad2"
                     /inference="alignment:Splign:2.1.0"
     exon            1770..1861
                     /gene="Naalad2"
                     /inference="alignment:Splign:2.1.0"
     exon            1862..1952
                     /gene="Naalad2"
                     /inference="alignment:Splign:2.1.0"
     exon            1953..2217
                     /gene="Naalad2"
                     /inference="alignment:Splign:2.1.0"
     exon            2218..2299
                     /gene="Naalad2"
                     /inference="alignment:Splign:2.1.0"
     exon            2300..2392
                     /gene="Naalad2"
                     /inference="alignment:Splign:2.1.0"
     exon            2393..2993
                     /gene="Naalad2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tccttaagga agcttcttcg tgaagggagg tgaagcttaa aagtagatct tgtggacttt
       61 gaaaaatttc aggaaaagga tgcaaacagc tggttttaga ttgaagaatt attgcagttt
      121 tttgaaggtt tagatatggg atgtgaagga aactgaggag taatatgagg aactggtgtc
      181 aaagatgaga ttcactacca ataaaaggcc caagactctg gaaccagcga atcacacttt
      241 ttacaatgga ttttcaggac tcaggctgta gatgccgtaa gatagggctt cagcgatgtt
      301 catattgcag accccaggcc tgcagttgca gtcagaggca ctctctgacc caaaaaggca
      361 tggccagacc taggcaactc cggggcctag gaatgtgcat tactgcggtg ctggcctcct
      421 tcatcatggg ctttactgtg ggttggttta ctaagcctct caaagaaaca actacttcat
      481 ctgcttatca tcaaagtata caacagaaac tcttgtctga aatgaaagct gaaaatatta
      541 gatcatttct tcgttccttt acaaaacttc cccatctggc aggaacggaa caaaatttac
      601 tacttgccaa gaaaatccaa acacaatgga agaaattcgg attagattca gccaacctgg
      661 ttcattatga tgttctcttg tcttacccaa atgagacaaa tgcaaactat gtatccattg
      721 tggatgaaca tggagctgag atttttaaaa catcatacct tgagccacca ccagatggat
      781 atgagaatgt cacaaacatc gtaccaccat ataatgcatt ttcagcccat gggatgccag
      841 agggagagct tgtgtatgtc aactatgctc gtactgagga cttcttcaaa ctagaaagag
      901 agatgcacat caactgcact ggcaagattg ttattgcaag atatgggaaa atctttagag
      961 gaaacaaagt caaaaatgcc atgctagctg gagccatggg aatcattctg tactctgatc
     1021 cagctgacta ctttgcccct ggtgtacagc catatcccaa aggatggaac cttcctggag
     1081 ctgcagccca gagaggaaat gtcttaaatc tgaatggggc aggtgaccca ctcactccag
     1141 gttatccagc taaagaatat accttcagac ttcctgttga agaagcagtg gggattccaa
     1201 acatacctgt acatccaatt ggatataatg atgcagagag actgttacgc aacttgggag
     1261 gaactgctcc accagaccaa agctggaagg gaagtctaaa tgttagttac aatattgggc
     1321 ctggcttttc aggaagtgaa tattccagga aagttcgaat gcatgttcat aatattaaca
     1381 aaatcacaag aatttacaat gtaattggaa ctatcagagg gtctacagag cctgacaggt
     1441 atgtcattct cggaggtcat cgtgactcct gggtgtttgg agggattgac cctacgactg
     1501 ggacagcagt tttgcaagag attgcgcgaa gttttggaaa actggtgaat ggaggttgga
     1561 aacctaggag aactattatt tttgccagct gggatgcaga agagtttggg ctgctgggtt
     1621 caacagaatg ggctgaagag aatgcaaaga tcctacagga gagaagcatt gcttacatca
     1681 actcagattc ggctatagaa ggtaattaca ctctccgagt tgattgcact cctcttctcc
     1741 accagttggt gtataaagtg gcaagagaga tttccagtcc tgatgatggt tttgaaagta
     1801 aatcacttta tgaaagctgg ctggaaaaag acccttcacc tgaaaataaa gaacgtccta
     1861 gaatcaataa gttgggatct gggagtgatt ttgaggctta ctttcaaaga cttggaattg
     1921 cttcaggcag agctcgctac actaagaaca agaaaacaga taaatacagt agctatcctg
     1981 tataccatac catctatgag acgtttgaat tagtacagaa tttttatgat cccacattta
     2041 aaaagcagct ttctgtggct cagttacgag gagcattggt atatgagctt gcggactgtg
     2101 tagtcattcc tttcaacatt caagactatg cgaaagcctt gaaaaactat gcagcaagta
     2161 tcttcaattt atccaagaaa catgaccagc aattgagaga tcatggagta tcatttgatc
     2221 ccttattttc tgctgtgaaa aacttttcag aagctgcttc agactttcac agaagactta
     2281 cacaagttga tcttaataat cctactgcag tgagaattat gaatgaccaa cagatgcttc
     2341 ttgaaagagc attcatagat cctcttggtt taccggggag gccgttctac aggcacatca
     2401 tctttgctcc aagcagccac aacaaatatg ctggagaatc attccctggg atttatgatg
     2461 ccatgtttga tattgaaaat aaggcagaca ctcacctggc ctgggcagaa gtaaagaaac
     2521 acatttctat tgcagctttc acaattcaag cagcagcagg gaccctgaca gatgtgttat
     2581 aggaactttt ctgtcaagta gcttcatcac taaactaaac taaagctcag tgtctgagag
     2641 tgaaattgtt ggggagtggg tcttggccaa atggattccc tgcaaaaggt gctgctgaga
     2701 atctgaagaa aaaggcatct ttttctttga tgatttacaa aggcagacaa tcctaaaact
     2761 gtgattgtcg tgacaggttt tatcctccta ccttatttat ctgtaaagag ggtacttttt
     2821 taaactcata tgcatatcca gtgaaagtga aagaggaagc aagcccagtg ctctcaggca
     2881 gatgattgca tttgctgtgg tatgtacaca tacatgaatg cattctcata tcaggtaagc
     2941 ttggttcttt acttcatcaa ataagtgaaa ataaaaagtt atttaattta ctc
//
