LOCUS       NM_001304776            1424 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus N(alpha)-acetyltransferase 80, NatH catalytic
            subunit (Naa80), mRNA.
ACCESSION   NM_001304776 XM_003750583
VERSION     NM_001304776.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Wiame,E., Tahay,G., Tyteca,D., Vertommen,D., Stroobant,V.,
            Bommer,G.T. and Van Schaftingen,E.
  TITLE     NAT6 acetylates the N-terminus of different forms of actin
  JOURNAL   FEBS J 285 (17), 3299-3316 (2018)
   PUBMED   30028079
REFERENCE   2  (bases 1 to 1424)
  AUTHORS   Goris,M., Magin,R.S., Foyn,H., Myklebust,L.M., Varland,S., Ree,R.,
            Drazic,A., Bhambra,P., Stove,S.I., Baumann,M., Haug,B.E.,
            Marmorstein,R. and Arnesen,T.
  TITLE     Structural determinants and cellular environment define processed
            actin as the sole substrate of the N-terminal acetyltransferase
            NAA80
  JOURNAL   Proc Natl Acad Sci U S A 115 (17), 4405-4410 (2018)
   PUBMED   29581307
REFERENCE   3  (bases 1 to 1424)
  AUTHORS   Drazic,A., Aksnes,H., Marie,M., Boczkowska,M., Varland,S.,
            Timmerman,E., Foyn,H., Glomnes,N., Rebowski,G., Impens,F.,
            Gevaert,K., Dominguez,R. and Arnesen,T.
  TITLE     NAA80 is actin's N-terminal acetyltransferase and regulates
            cytoskeleton assembly and cell motility
  JOURNAL   Proc Natl Acad Sci U S A 115 (17), 4399-4404 (2018)
   PUBMED   29581253
REFERENCE   4  (bases 1 to 1424)
  AUTHORS   Zegerman,P., Bannister,A.J. and Kouzarides,T.
  TITLE     The putative tumour suppressor Fus-2 is an N-acetyltransferase
  JOURNAL   Oncogene 19 (1), 161-163 (2000)
   PUBMED   10644992
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Feb 12, 2015 this sequence version replaced XM_003750583.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC105845.1, SRR22399484.1235038.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-190               JAXUCZ010000008.1  117132957-117133146
            191-1424            JAXUCZ010000008.1  117134974-117136207
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q32"
     gene            1..1424
                     /gene="Naa80"
                     /gene_synonym="Nat6"
                     /note="N(alpha)-acetyltransferase 80, NatH catalytic
                     subunit"
                     /db_xref="GeneID:100910872"
                     /db_xref="RGD:6496422"
     exon            1..190
                     /gene="Naa80"
                     /gene_synonym="Nat6"
                     /inference="alignment:Splign:2.1.0"
     exon            191..1424
                     /gene="Naa80"
                     /gene_synonym="Nat6"
                     /inference="alignment:Splign:2.1.0"
     CDS             290..1228
                     /gene="Naa80"
                     /gene_synonym="Nat6"
                     /note="N-acetyltransferase 6-like; N-acetyltransferase 6
                     (GCN5-related)"
                     /codon_start=1
                     /product="N-alpha-acetyltransferase 80"
                     /protein_id="NP_001291705.1"
                     /db_xref="GeneID:100910872"
                     /db_xref="RGD:6496422"
                     /translation="MELILSTSPAKLTLDPACQPELTLRFNLTKLTLDPARQSELSLS
                     PRLAELTLDSTCHPEMSLSPGPAELTGDPQHQAKESLVPKLAELTLEPVHCRPELMSA
                     CADLINDQWPRSRASRLHSLGQSSDAFPLCLMLLSPQPTPGAAPIVVGHARLSRVLDH
                     PHSLLVETVVVARALRGRGFGRRLMEGLEAFARARGFQRLHLTTHDQLYFYAHLGYQL
                     GEPVQGLAFTNRRLPTNVLRAFSKPPCPQPPCKAPVLAAQAIPRSSKGPPLPPPPPLP
                     LTTSPPPSPEPLPQSPLETRYRDLKGCPIFWMEKDI"
ORIGIN      
        1 gtgtctaggt ggtgacattc cgggcactga gaacatagga ggaggtgcgc tgtctcctgc
       61 aaagactgca acgagtcctc cgtactgctg ggaccagcgt aggcagaccg aagagttgga
      121 gccagagaca gcgagttaac caaccgtgcg caggcaggac gcggagcatc ttggaactcg
      181 acttgaacat gaagtgacac agctgagcct ggatcctacc tgtaggcaag agctgactct
      241 gagccctggc ccagtcaagc tgacccctac cttagacccc gtgcaccgga tggagctgat
      301 cctgagtacc agcccagcaa agctgactct agatcctgca tgccagccag agttgaccct
      361 gagattcaac ctgaccaagc taaccctgga tcctgcacgc cagtcagagc tgtcgctgag
      421 tcccagacta gctgagctga ccctggattc cacatgccac ccagagatga gcctcagtcc
      481 tggcccagct gagcttaccg gggatcctca acaccaggca aaggagagcc tggtccccaa
      541 gctggctgaa ttgaccctgg agcctgtgca ctgccgaccg gagctcatga gtgcctgtgc
      601 tgacctcatc aatgaccagt ggccccgtag tcgtgcctcc cgtctccact ccctgggcca
      661 gtcttcagac gccttccccc tctgcttgat gctgctgagc cctcagccca cacctggagc
      721 agcccctatt gtggtgggcc atgcccgctt atcacgggta ctggaccatc cccacagcct
      781 cttagtggag acagtggtgg tagcccgggc tctgaggggc cgtggctttg gccgccgcct
      841 catggagggc ttggaggcct ttgcccgagc ccggggtttc caacggctgc acctcaccac
      901 tcatgatcag ctatatttct acgcccatct gggctaccaa ctgggtgagc ctgtgcaggg
      961 tttggccttt accaaccgtc ggctgcccac caatgtccta cgtgccttct ctaagccacc
     1021 ctgtccccaa ccaccctgca aggcgcctgt cctagctgcc caagctatcc caaggagctc
     1081 caagggaccc ccattgccac cacctcctcc tctgcctctg accacctcac cccctccttc
     1141 acccgagccc cttcctcaaa gcccgttaga gacacgatat cgagatctga aggggtgccc
     1201 tatattctgg atggaaaaag acatctgatg gccctgtctc tctgggacac tggattgccc
     1261 agaacagagc cagcctcagc ccacaggcca tatacttcag cccctccccc taggggacaa
     1321 ccttagcctg tgtatctttt ctgggtacca gtgggccagg aggtggactt ggagctttgg
     1381 ctcagagctg tcagtttggc taaaataaag gcttccatta ggta
//
