LOCUS       NM_001135839             938 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus N(alpha)-acetyltransferase 10, NatA catalytic
            subunit (Naa10), mRNA.
ACCESSION   NM_001135839 XM_343842
VERSION     NM_001135839.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 938)
  AUTHORS   Xu,K. and Zhang,Y.
  TITLE     Down-regulation of NAA10 mediates the neuroprotection induced by
            sevoflurane preconditioning via regulating ERK1/2 phosphorylation
  JOURNAL   Neurosci Lett 755, 135897 (2021)
   PUBMED   33872734
  REMARK    GeneRIF: Down-regulation of NAA10 mediates the neuroprotection
            induced by sevoflurane preconditioning via regulating ERK1/2
            phosphorylation.
REFERENCE   2  (bases 1 to 938)
  AUTHORS   Seo,J.H., Park,J.H., Lee,E.J., Vo,T.T., Choi,H., Kim,J.Y.,
            Jang,J.K., Wee,H.J., Lee,H.S., Jang,S.H., Park,Z.Y., Jeong,J.,
            Lee,K.J., Seok,S.H., Park,J.Y., Lee,B.J., Lee,M.N., Oh,G.T. and
            Kim,K.W.
  TITLE     ARD1-mediated Hsp70 acetylation balances stress-induced protein
            refolding and degradation
  JOURNAL   Nat Commun 7, 12882 (2016)
   PUBMED   27708256
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 938)
  AUTHORS   Rong,Z., Ouyang,Z., Magin,R.S., Marmorstein,R. and Yu,H.
  TITLE     Opposing Functions of the N-terminal Acetyltransferases Naa50 and
            NatA in Sister-chromatid Cohesion
  JOURNAL   J Biol Chem 291 (36), 19079-19091 (2016)
   PUBMED   27422821
REFERENCE   4  (bases 1 to 938)
  AUTHORS   Myklebust,L.M., Van Damme,P., Stove,S.I., Dorfel,M.J., Abboud,A.,
            Kalvik,T.V., Grauffel,C., Jonckheere,V., Wu,Y., Swensen,J.,
            Kaasa,H., Liszczak,G., Marmorstein,R., Reuter,N., Lyon,G.J.,
            Gevaert,K. and Arnesen,T.
  TITLE     Biochemical and cellular analysis of Ogden syndrome reveals
            downstream Nt-acetylation defects
  JOURNAL   Hum Mol Genet 24 (7), 1956-1976 (2015)
   PUBMED   25489052
REFERENCE   5  (bases 1 to 938)
  AUTHORS   Aksnes,H., Van Damme,P., Goris,M., Starheim,K.K., Marie,M.,
            Stove,S.I., Hoel,C., Kalvik,T.V., Hole,K., Glomnes,N., Furnes,C.,
            Ljostveit,S., Ziegler,M., Niere,M., Gevaert,K. and Arnesen,T.
  TITLE     An organellar nalpha-acetyltransferase, naa60, acetylates cytosolic
            N termini of transmembrane proteins and maintains Golgi integrity
  JOURNAL   Cell Rep 10 (8), 1362-1374 (2015)
   PUBMED   25732826
REFERENCE   6  (bases 1 to 938)
  AUTHORS   Yoon,H., Kim,H.L., Chun,Y.S., Shin,D.H., Lee,K.H., Shin,C.S.,
            Lee,D.Y., Kim,H.H., Lee,Z.H., Ryoo,H.M., Lee,M.N., Oh,G.T. and
            Park,J.W.
  TITLE     NAA10 controls osteoblast differentiation and bone formation as a
            feedback regulator of Runx2
  JOURNAL   Nat Commun 5, 5176 (2014)
   PUBMED   25376646
  REMARK    GeneRIF: NAA10 acts as a guard ensuring balanced osteogenesis by
            fine-tuning Runx2 signalling in a feedback manner.
            Publication Status: Online-Only
REFERENCE   7  (bases 1 to 938)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   8  (bases 1 to 938)
  AUTHORS   Arnesen,T., Gromyko,D., Kagabo,D., Betts,M.J., Starheim,K.K.,
            Varhaug,J.E., Anderson,D. and Lillehaug,J.R.
  TITLE     A novel human NatA Nalpha-terminal acetyltransferase complex:
            hNaa16p-hNaa10p (hNat2-hArd1)
  JOURNAL   BMC Biochem 10, 15 (2009)
   PUBMED   19480662
  REMARK    Publication Status: Online-Only
REFERENCE   9  (bases 1 to 938)
  AUTHORS   Arnesen,T., Anderson,D., Baldersheim,C., Lanotte,M., Varhaug,J.E.
            and Lillehaug,J.R.
  TITLE     Identification and characterization of the human ARD1-NATH protein
            acetyltransferase complex
  JOURNAL   Biochem J 386 (Pt 3), 433-443 (2005)
   PUBMED   15496142
REFERENCE   10 (bases 1 to 938)
  AUTHORS   Sugiura,N., Adams,S.M. and Corriveau,R.A.
  TITLE     An evolutionarily conserved N-terminal acetyltransferase complex
            associated with neuronal development
  JOURNAL   J Biol Chem 278 (41), 40113-40120 (2003)
   PUBMED   12888564
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000021.1.
            
            On Oct 15, 2008 this sequence version replaced XM_343842.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643292.66467.1,
                                           SRR26643291.44786.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-164               JAXUCZ010000021.1  156812411-156812574 c
            165-263             JAXUCZ010000021.1  156811935-156812033 c
            264-322             JAXUCZ010000021.1  156811490-156811548 c
            323-368             JAXUCZ010000021.1  156810567-156810612 c
            369-484             JAXUCZ010000021.1  156810358-156810473 c
            485-529             JAXUCZ010000021.1  156810059-156810103 c
            530-614             JAXUCZ010000021.1  156808396-156808480 c
            615-938             JAXUCZ010000021.1  156807378-156807701 c
FEATURES             Location/Qualifiers
     source          1..938
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq37"
     gene            1..938
                     /gene="Naa10"
                     /gene_synonym="Ard1; Ard1a; RGD1565315"
                     /note="N(alpha)-acetyltransferase 10, NatA catalytic
                     subunit"
                     /db_xref="GeneID:363518"
                     /db_xref="RGD:1565315"
     exon            1..164
                     /gene="Naa10"
                     /gene_synonym="Ard1; Ard1a; RGD1565315"
                     /inference="alignment:Splign:2.1.0"
     CDS             144..851
                     /gene="Naa10"
                     /gene_synonym="Ard1; Ard1a; RGD1565315"
                     /EC_number="2.3.1.88"
                     /note="N-acetyltransferase ARD1 homolog;
                     alpha-N-acetyltransferase 1A"
                     /codon_start=1
                     /product="N-alpha-acetyltransferase 10"
                     /protein_id="NP_001129311.1"
                     /db_xref="GeneID:363518"
                     /db_xref="RGD:1565315"
                     /translation="MNIRNARPEDLMNMQHCNLLCLPENYQMKYYFYHGLSWPQLSYI
                     AEDENGKIVGYVLAKMEEDPDDVPHGHITSLAVKRSHRRLGLAQKLMDQASRAMIENF
                     NAKYVSLHVRKSNRAALHLYSNTLNFQISEVEPKYYADGEDAYAMKRDLTQMADELRR
                     HLELKEKGRHMVLSAMENKAENKGNVLLSSGEACREEKGLTAEDSGGDSKDLSEVSET
                     TESTDVKDSSEASDSAS"
     exon            165..263
                     /gene="Naa10"
                     /gene_synonym="Ard1; Ard1a; RGD1565315"
                     /inference="alignment:Splign:2.1.0"
     exon            264..322
                     /gene="Naa10"
                     /gene_synonym="Ard1; Ard1a; RGD1565315"
                     /inference="alignment:Splign:2.1.0"
     exon            323..368
                     /gene="Naa10"
                     /gene_synonym="Ard1; Ard1a; RGD1565315"
                     /inference="alignment:Splign:2.1.0"
     exon            369..484
                     /gene="Naa10"
                     /gene_synonym="Ard1; Ard1a; RGD1565315"
                     /inference="alignment:Splign:2.1.0"
     exon            485..529
                     /gene="Naa10"
                     /gene_synonym="Ard1; Ard1a; RGD1565315"
                     /inference="alignment:Splign:2.1.0"
     exon            530..614
                     /gene="Naa10"
                     /gene_synonym="Ard1; Ard1a; RGD1565315"
                     /inference="alignment:Splign:2.1.0"
     exon            615..938
                     /gene="Naa10"
                     /gene_synonym="Ard1; Ard1a; RGD1565315"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcggcccacc tcttccgctg ctgccccagg tttctggccc cagtcccagc cccggctcct
       61 atcgtcccta ccctgtttct gagtggccgc cgagcgcacg cgttcacgat ccacagggac
      121 ccacgagctc cgccgccgcc gtgatgaaca tccgcaatgc taggcccgag gacctgatga
      181 acatgcagca ctgcaacctt ctgtgcctgc ctgagaacta ccagatgaag tattatttct
      241 atcatggcct ctcttggccc cagctttctt acattgctga ggatgagaat gggaagattg
      301 tgggatacgt cttggctaaa atggaagagg acccagacga tgtgccccat ggacatatca
      361 cctcactggc tgtgaaacgt tcccaccggc gccttggcct ggctcagaag ctgatggacc
      421 aggcctctcg agccatgata gaaaacttca atgccaaata tgtctcccta catgtcagga
      481 agagtaaccg ggctgcccta catctctatt ccaacaccct caactttcag atcagcgaag
      541 tggagcccaa atactatgca gatggggaag atgcatatgc aatgaagcgg gacctcacgc
      601 agatggctga tgagctgagg cggcacctgg agctgaagga aaagggcagg cacatggtgc
      661 tgtcggccat ggagaacaag gcggagaaca aaggcaacgt gcttctgagc tcaggagagg
      721 cctgtcgtga ggagaagggc ctgactgctg aggatagtgg tggggacagc aaggacctca
      781 gtgaggtcag tgagaccaca gaaagcacag atgtcaaaga cagctcagag gcctctgatt
      841 ctgcctccta gaacctgccc tacctggtcc caacctcacc ccatgtgctt tttacaataa
      901 atgtcaccca gtggccttgg gaaatttgtg aatgtgca
//
