LOCUS       NP_001102085             922 aa            linear   ROD 03-APR-2024
DEFINITION  myelin transcription factor 1 [Rattus norvegicus].
ACCESSION   NP_001102085 XP_001055147 XP_342606
VERSION     NP_001102085.1
DBSOURCE    REFSEQ: accession NM_001108615.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 922)
  AUTHORS   Bahi,A. and Dreyer,J.L.
  TITLE     Viral-mediated overexpression of the Myelin Transcription Factor 1
            (MyT1) in the dentate gyrus attenuates anxiety- and ethanol-related
            behaviors in rats
  JOURNAL   Psychopharmacology (Berl) 234 (12), 1829-1840 (2017)
   PUBMED   28303373
  REMARK    GeneRIF: MyT1 overexpression produced anxiolytic-like effects and
            decreased ethanol intake.
REFERENCE   2  (residues 1 to 922)
  AUTHORS   Andrews,J.L., Newell,K.A., Matosin,N., Huang,X.F. and
            Fernandez-Enright,F.
  TITLE     Alterations of p75 neurotrophin receptor and Myelin transcription
            factor 1 in the hippocampus of perinatal phencyclidine treated rats
  JOURNAL   Prog Neuropsychopharmacol Biol Psychiatry 63, 91-97 (2015)
   PUBMED   26071990
  REMARK    GeneRIF: This study suggested that alterations of p75 neurotrophin
            receptor and Myelin transcription factor 1 in the hippocampus of
            perinatal phencyclidine treated rats
REFERENCE   3  (residues 1 to 922)
  AUTHORS   Wang,S., Zhang,J., Zhao,A., Hipkens,S., Magnuson,M.A. and Gu,G.
  TITLE     Loss of Myt1 function partially compromises endocrine islet cell
            differentiation and pancreatic physiological function in the mouse
  JOURNAL   Mech Dev 124 (11-12), 898-910 (2007)
   PUBMED   17928203
REFERENCE   4  (residues 1 to 922)
  AUTHORS   Aruga,J., Yoshikawa,F., Nozaki,Y., Sakaki,Y., Toyoda,A. and
            Furuichi,T.
  TITLE     An oligodendrocyte enhancer in a phylogenetically conserved intron
            region of the mammalian myelin gene Opalin
  JOURNAL   J Neurochem 102 (5), 1533-1547 (2007)
   PUBMED   17442045
REFERENCE   5  (residues 1 to 922)
  AUTHORS   Kim,J.G., Armstrong,R.C., v Agoston,D., Robinsky,A., Wiese,C.,
            Nagle,J. and Hudson,L.D.
  TITLE     Myelin transcription factor 1 (Myt1) of the oligodendrocyte
            lineage, along with a closely related CCHC zinc finger, is
            expressed in developing neurons in the mammalian central nervous
            system
  JOURNAL   J Neurosci Res 50 (2), 272-290 (1997)
   PUBMED   9373037
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474066.1.
            
            [WARNING] On Apr 9, 2024 this sequence was replaced by
            NP_001102085.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XP_342606.2, XP_001055147.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132276,
                              SAMD00132278 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..922
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q43"
     Protein         1..922
                     /product="myelin transcription factor 1"
                     /calculated_mol_wt=101411
     Region          238..264
                     /region_name="zf-C2HC"
                     /note="Zinc finger, C2HC type; pfam01530"
                     /db_xref="CDD:460240"
     Region          282..310
                     /region_name="zf-C2HC"
                     /note="Zinc finger, C2HC type; pfam01530"
                     /db_xref="CDD:460240"
     Region          357..588
                     /region_name="MYT1"
                     /note="Myelin transcription factor 1; pfam08474"
                     /db_xref="CDD:462489"
     Region          596..624
                     /region_name="zf-C2HC"
                     /note="Zinc finger, C2HC type; pfam01530"
                     /db_xref="CDD:460240"
     Region          640..668
                     /region_name="zf-C2HC"
                     /note="Zinc finger, C2HC type; pfam01530"
                     /db_xref="CDD:460240"
     Region          689..717
                     /region_name="zf-C2HC"
                     /note="Zinc finger, C2HC type; pfam01530"
                     /db_xref="CDD:460240"
     Region          742..770
                     /region_name="zf-C2HC"
                     /note="Zinc finger, C2HC type; pfam01530"
                     /db_xref="CDD:460240"
     Region          <799..>867
                     /region_name="COG4372"
                     /note="Uncharacterized protein, contains DUF3084 domain
                     [Function unknown]"
                     /db_xref="CDD:443500"
     CDS             1..922
                     /gene="Myt1"
                     /coded_by="NM_001108615.1:983..3751"
                     /db_xref="GeneID:362291"
                     /db_xref="RGD:1304899"
ORIGIN      
        1 mvansdegek dlfiqpedve evievtsers qepcpqslkd mvneesskqk gvlgheeeee
       61 eeeeeeeeee egeegeeeee eeeeedeede eedeeeeeee eeaasnvlfg ddtthtsvqk
      121 assefrgpel sspkpeysvi vevrsdddkd edshsqksav tdesemydmm trgnlglleq
      181 aialkaeqvr avcesgcppa eqghlgpgep gkmakpldvv rkscynkdps rvekreikcp
      241 tpgcdgtghv tglyphhrsl sgcphkdrip peilamhenv lkcptpgctg qghvnsnrnt
      301 hrslsgcpia aaeklakshe kqqlqtgdpp knnsnsdril rpmcfvkqle vppygsyrpn
      361 vapttpranl akelekfskv tfdyasfdaq vfgkrmlapk iqtsetspka fqcfdyshda
      421 eaahmaatai lnlstrcwem penlstkpqd lpskavdiev dengtldlsm hkhrkrentf
      481 psssscsssp gvkspdvsqr qsstsapsss mtspqssqas rqdewdrpld ytkpsrlree
      541 epeesepaah sfasseaddq evseenfeer kypgevtltn fklkflskdi kkelltcptp
      601 gcdgsghitg nyashrslsg cpladkslrn lmaahsadlk cptpgcdgsg hitgnyashr
      661 slsgcprakk sglkvaptkd dkedpelmkc pvpgcvglgh isgkyashrs asgcplaarr
      721 qkegalngss fswkslkneg ptcptpgcdg sghangsflt hrslsgcpra tfagkkgkls
      781 gdeilspkfk tsdvlendee ikqlnqeird lnesnlemea amvqlqsqis smeknlknie
      841 eenklieeqn ealflelsgl sqaliqslan irlphlepic eqnfdayvnt ltdmysnqdc
      901 yqnpenkgll etikqavrgi qv
//
