LOCUS       NM_001109097            1242 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus myozenin 1 (Myoz1), mRNA.
ACCESSION   NM_001109097 XM_001064588 XM_573691
VERSION     NM_001109097.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1242)
  AUTHORS   Shenkman BS and Lomonosova YN.
  TITLE     Expression of calsarcin isoforms and myosin phenotype stabilization
            in transitional unloaded muscle
  JOURNAL   Dokl Biochem Biophys 459, 214-216 (2014)
   PUBMED   25559982
  REMARK    GeneRIF: Results suggest that under weightlessness conditions, in
            some muscle fibers with a large proportion of fast MHC isoforms,
            the increased expression of calsarcin--2 can prevent the
            compensatory enhancement of the calcineurin pathway
REFERENCE   2  (bases 1 to 1242)
  AUTHORS   Frey N, Frank D, Lippl S, Kuhn C, Kogler H, Barrientos T, Rohr C,
            Will R, Muller OJ, Weiler H, Bassel-Duby R, Katus HA and Olson EN.
  TITLE     Calsarcin-2 deficiency increases exercise capacity in mice through
            calcineurin/NFAT activation
  JOURNAL   J Clin Invest 118 (11), 3598-3608 (2008)
   PUBMED   18846255
REFERENCE   3  (bases 1 to 1242)
  AUTHORS   Faulkner G, Pallavicini A, Comelli A, Salamon M, Bortoletto G,
            Ievolella C, Trevisan S, Kojic' S, Dalla Vecchia F, Laveder P,
            Valle G and Lanfranchi G.
  TITLE     FATZ, a filamin-, actinin-, and telethonin-binding protein of the
            Z-disc of skeletal muscle
  JOURNAL   J Biol Chem 275 (52), 41234-41242 (2000)
   PUBMED   10984498
REFERENCE   4  (bases 1 to 1242)
  AUTHORS   Frey N, Richardson JA and Olson EN.
  TITLE     Calsarcins, a novel family of sarcomeric calcineurin-binding
            proteins
  JOURNAL   Proc Natl Acad Sci U S A 97 (26), 14632-14637 (2000)
   PUBMED   11114196
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474061.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_573691.2, XM_001064588.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ215918.1, FQ215077.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1242
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p16"
     gene            1..1242
                     /gene="Myoz1"
                     /gene_synonym="RGD1561064"
                     /note="myozenin 1"
                     /db_xref="GeneID:498440"
                     /db_xref="RGD:1561064"
     exon            1..64
                     /gene="Myoz1"
                     /gene_synonym="RGD1561064"
                     /inference="alignment:Splign:2.1.0"
     exon            65..155
                     /gene="Myoz1"
                     /gene_synonym="RGD1561064"
                     /inference="alignment:Splign:2.1.0"
     CDS             83..973
                     /gene="Myoz1"
                     /gene_synonym="RGD1561064"
                     /codon_start=1
                     /product="myozenin-1"
                     /protein_id="NP_001102567.1"
                     /db_xref="GeneID:498440"
                     /db_xref="RGD:1561064"
                     /translation="MPLSGTPAPNKRRKSSKLIMELTGGGRESSGLNLGKKISVPRDV
                     MLEELSLLTNRGSKMFKLRQMRVEKFIYENHPDVFSDSSMDHFQKFLPTVGGQLESAG
                     QGFSYGKGSSGGQAGASGSAGQYGSDRHQQGSGFGAGGAGGPGGQAGGGAAPGTVGVG
                     EPGSGDQAGGDGKHVTVFKTYISPWDRAMGVDPQQKVELGIDLLAYGAKAELPKYKSF
                     NRTAMPYGGYEKASKRMTFQMPKFDLGPLLSEPLVLYNQNLSNRPSFNRTPIPWLSSG
                     EHVDYSVDIGIPLDGETEEL"
     exon            156..334
                     /gene="Myoz1"
                     /gene_synonym="RGD1561064"
                     /inference="alignment:Splign:2.1.0"
     exon            335..575
                     /gene="Myoz1"
                     /gene_synonym="RGD1561064"
                     /inference="alignment:Splign:2.1.0"
     exon            576..741
                     /gene="Myoz1"
                     /gene_synonym="RGD1561064"
                     /inference="alignment:Splign:2.1.0"
     exon            742..1242
                     /gene="Myoz1"
                     /gene_synonym="RGD1561064"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acagcagctc agtcatccaa agctgctgga ccccagggag agctgaccac caactgagag
       61 gctggtcaaa tccccctcca ccatgccgct ctcgggaacc ccggccccta acaagaggag
      121 gaagtcaagc aaactgatta tggagctcac tggaggcggt cgggagagtt cgggcctgaa
      181 cctgggcaag aagatcagtg tcccgaggga tgtgatgttg gaggagttgt cgctccttac
      241 caaccgaggc tccaagatgt tcaagctgcg gcagatgcgg gtggagaaat ttatctatga
      301 aaaccacccc gatgttttct ctgacagctc aatggatcac ttccagaagt ttcttcccac
      361 agtgggagga cagctggagt cagctggtca gggcttctcc tatggcaagg gcagcagcgg
      421 aggccaggct ggggccagtg gctctgctgg acagtatggc tctgaccgcc atcagcaggg
      481 ctctgggttt ggagctgggg gtgcaggtgg tcctgggggc caggctggcg gaggagcagc
      541 tcccggcaca gtaggggttg gagagccagg atcaggtgac caggcaggtg gagatgggaa
      601 acacgtcact gtgttcaaga catatatttc cccgtgggat cgggccatgg gggtcgaccc
      661 tcagcaaaaa gtggaacttg gcattgacct gctggcatat ggcgccaaag ctgaactccc
      721 caagtataag tcctttaaca ggacggcaat gccctatggt ggatatgaga aggcctccaa
      781 acgaatgacc ttccagatgc ccaagtttga cctggggcct ctgctgagtg aacccttggt
      841 cctctacaac cagaacctct ccaacaggcc ttctttcaat cgaaccccta ttccctggtt
      901 gagctctggg gagcatgtag actacagcgt ggatatcggc atacccttgg atggagagac
      961 agaggagctg tgaagtgtct cctcctgtcg tatgcatcat ttcccctttc tggttccaat
     1021 ttgagagggg acgctggaca ggatgcccca actgttactc cagtatcctt gtggcaatgg
     1081 agggtagagg gtgggagcct ttccaccctt caagttccca ctccagagca cccctcctga
     1141 ccagctaaga gctcccatcc tgctgttcca tatggaatct gctcttttat ggaattttct
     1201 ctgccactgg taacagtcaa taaactctaa ggaaatgaac tc
//
