LOCUS       NM_001169141            4513 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus myomesin 2 (Myom2), mRNA.
ACCESSION   NM_001169141 XM_001074764 XM_240481
VERSION     NM_001169141.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4513)
  AUTHORS   Ji,M., Su,L., Liu,L., Zhuang,M., Xiao,J., Guan,Y., Zhu,S., Ma,L.
            and Pu,H.
  TITLE     CaMKII regulates the proteins TPM1 and MYOM2 and promotes
            diacetylmorphine-induced abnormal cardiac rhythms
  JOURNAL   Sci Rep 13 (1), 5827 (2023)
   PUBMED   37037889
  REMARK    GeneRIF: CaMKII regulates the proteins TPM1 and MYOM2 and promotes
            diacetylmorphine-induced abnormal cardiac rhythms.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4513)
  AUTHORS   Rozanski,A., Takano,A.P., Kato,P.N., Soares,A.G., Lellis-Santos,C.,
            Campos,J.C., Ferreira,J.C., Barreto-Chaves,M.L. and Moriscot,A.S.
  TITLE     M-protein is down-regulated in cardiac hypertrophy driven by
            thyroid hormone in rats
  JOURNAL   Mol Endocrinol 27 (12), 2055-2065 (2013)
   PUBMED   24176915
  REMARK    GeneRIF: the M-protein expression is strongly and rapidly repressed
            by triiodothyronine in cardiomyocytes.
REFERENCE   3  (bases 1 to 4513)
  AUTHORS   Zhao,X., Leon,I.R., Bak,S., Mogensen,M., Wrzesinski,K., Hojlund,K.
            and Jensen,O.N.
  TITLE     Phosphoproteome analysis of functional mitochondria isolated from
            resting human muscle reveals extensive phosphorylation of inner
            membrane protein complexes and enzymes
  JOURNAL   Mol Cell Proteomics 10 (1), M110.000299 (2011)
   PUBMED   20833797
REFERENCE   4  (bases 1 to 4513)
  AUTHORS   Gokhin,D.S., Lewis,R.A., McKeown,C.R., Nowak,R.B., Kim,N.E.,
            Littlefield,R.S., Lieber,R.L. and Fowler,V.M.
  TITLE     Tropomodulin isoforms regulate thin filament pointed-end capping
            and skeletal muscle physiology
  JOURNAL   J Cell Biol 189 (1), 95-109 (2010)
   PUBMED   20368620
REFERENCE   5  (bases 1 to 4513)
  AUTHORS   Beqqali,A., Monshouwer-Kloots,J., Monteiro,R., Welling,M.,
            Bakkers,J., Ehler,E., Verkleij,A., Mummery,C. and Passier,R.
  TITLE     CHAP is a newly identified Z-disc protein essential for heart and
            skeletal muscle function
  JOURNAL   J Cell Sci 123 (Pt 7), 1141-1150 (2010)
   PUBMED   20215401
REFERENCE   6  (bases 1 to 4513)
  AUTHORS   Hornemann,T., Kempa,S., Himmel,M., Hayess,K., Furst,D.O. and
            Wallimann,T.
  TITLE     Muscle-type creatine kinase interacts with central domains of the
            M-band proteins myomesin and M-protein
  JOURNAL   J Mol Biol 332 (4), 877-887 (2003)
   PUBMED   12972258
REFERENCE   7  (bases 1 to 4513)
  AUTHORS   Porter,J.D., Merriam,A.P., Gong,B., Kasturi,S., Zhou,X.,
            Hauser,K.F., Andrade,F.H. and Cheng,G.
  TITLE     Postnatal suppression of myomesin, muscle creatine kinase and the
            M-line in rat extraocular muscle
  JOURNAL   J Exp Biol 206 (Pt 17), 3101-3112 (2003)
   PUBMED   12878677
REFERENCE   8  (bases 1 to 4513)
  AUTHORS   Schiaffino,S. and Reggiani,C.
  TITLE     Molecular diversity of myofibrillar proteins: gene regulation and
            functional significance
  JOURNAL   Physiol Rev 76 (2), 371-423 (1996)
   PUBMED   8618961
  REMARK    Review article
REFERENCE   9  (bases 1 to 4513)
  AUTHORS   Vinkemeier,U., Obermann,W., Weber,K. and Furst,D.O.
  TITLE     The globular head domain of titin extends into the center of the
            sarcomeric M band. cDNA cloning, epitope mapping and immunoelectron
            microscopy of two titin-associated proteins
  JOURNAL   J Cell Sci 106 (Pt 1), 319-330 (1993)
   PUBMED   7505783
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000016.1.
            
            On or before Dec 17, 2009 this sequence version replaced
            XM_240481.4, XM_001074764.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643296.35917.1,
                                           SRR26643289.38900.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-107               JAXUCZ010000016.1  81292317-81292423   c
            108-225             JAXUCZ010000016.1  81288480-81288597   c
            226-381             JAXUCZ010000016.1  81286964-81287119   c
            382-520             JAXUCZ010000016.1  81283207-81283345   c
            521-678             JAXUCZ010000016.1  81282919-81283076   c
            679-771             JAXUCZ010000016.1  81281922-81282014   c
            772-860             JAXUCZ010000016.1  81274894-81274982   c
            861-911             JAXUCZ010000016.1  81274752-81274802   c
            912-1076            JAXUCZ010000016.1  81271407-81271571   c
            1077-1238           JAXUCZ010000016.1  81271100-81271261   c
            1239-1380           JAXUCZ010000016.1  81268520-81268661   c
            1381-1580           JAXUCZ010000016.1  81266850-81267049   c
            1581-1634           JAXUCZ010000016.1  81266173-81266226   c
            1635-1762           JAXUCZ010000016.1  81258530-81258657   c
            1763-1946           JAXUCZ010000016.1  81257229-81257412   c
            1947-2121           JAXUCZ010000016.1  81253839-81254013   c
            2122-2243           JAXUCZ010000016.1  81252232-81252353   c
            2244-2431           JAXUCZ010000016.1  81249721-81249908   c
            2432-2558           JAXUCZ010000016.1  81247858-81247984   c
            2559-2737           JAXUCZ010000016.1  81247432-81247610   c
            2738-2852           JAXUCZ010000016.1  81245909-81246023   c
            2853-3009           JAXUCZ010000016.1  81244931-81245087   c
            3010-3116           JAXUCZ010000016.1  81244738-81244844   c
            3117-3161           JAXUCZ010000016.1  81242215-81242259   c
            3162-3298           JAXUCZ010000016.1  81241693-81241829   c
            3299-3443           JAXUCZ010000016.1  81238393-81238537   c
            3444-3503           JAXUCZ010000016.1  81238210-81238269   c
            3504-3571           JAXUCZ010000016.1  81236883-81236950   c
            3572-3688           JAXUCZ010000016.1  81233785-81233901   c
            3689-3776           JAXUCZ010000016.1  81233527-81233614   c
            3777-3815           JAXUCZ010000016.1  81232820-81232858   c
            3816-3921           JAXUCZ010000016.1  81230967-81231072   c
            3922-4085           JAXUCZ010000016.1  81227312-81227475   c
            4086-4122           JAXUCZ010000016.1  81227053-81227089   c
            4123-4145           JAXUCZ010000016.1  81225359-81225381   c
            4146-4201           JAXUCZ010000016.1  81224829-81224884   c
            4202-4513           JAXUCZ010000016.1  81222939-81223250   c
FEATURES             Location/Qualifiers
     source          1..4513
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16q12.5"
     gene            1..4513
                     /gene="Myom2"
                     /note="myomesin 2"
                     /db_xref="GeneID:306616"
                     /db_xref="RGD:631437"
     exon            1..107
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            108..225
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     CDS             119..4513
                     /gene="Myom2"
                     /codon_start=1
                     /product="myomesin-2"
                     /protein_id="NP_001162612.1"
                     /db_xref="GeneID:306616"
                     /db_xref="RGD:631437"
                     /translation="MSLVVVPFYQKRHKHFDQSYRNIQTRYLLDRYASKKQASSQSSS
                     QRSLTERSSSKRASSQSSAEGMTCRLCAKRMSASEEEEVENENRYRSLAASYGEAKRQ
                     RFLSELAQLEENVQLARTQARNKLDKYFLEQTVADNLALERSSFEDRLSRAPEILVRL
                     RSHTIWERMSVRLCFTVQGFPTPVVQWYKDGSLICQAGEPGKYRIESRYGVHTLEINR
                     ADFEDTATYSAVATNPHGQVSTNAAVVVRRYRGDEEPYHSVGLPIGLPLSSVIPYTHF
                     DVQFLEKFGVTFRREGETVTLKCTLLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFG
                     EGQASLSFSHLNKDDEGLYTLRIVSRGGVSDHSAFMFVRDADPLVTGAPGAPMDLQCH
                     DANRDYVIVTWKPPNTTTESPVIGYFIDKCEVGTNNWVQCNDAPVKICKYPVTGLFEG
                     RSYVFRVRAVNNAGISRPSRISDAVAALDPVDLRRLQAIHLEGEKEIVIYQDDLEGDV
                     QIPGPPTNVQASEVSRNYVVLSWDPPSPRGKEPLMYFIEKSAVGSGSWQRVNAQTAVR
                     SPRYAVFDLAEGKSYVFRVLSANKHGLSDPSEITPPIQAQDMIVVPSAPGRVLASRNT
                     KTSVVVQWDRPKHEEDLLGYYVDCCVAGTNMWEPCNHKPIGYNRFVVHGLTTGEQYIF
                     RVKAVNAVGTSENSQESEVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGS
                     AIIGYYLDKREVHHKNWHEINSSPVKERILTVEGLTEGSLYEFKIAATNLAGIGQPSD
                     PSEHFKCEAWTAPEPGPAYDLTFCEVRDTSLVILWKAPVYSGSSPVSGYFVDFKEEDS
                     GEWKTTSEAATPNRYLKVCDLHQGKTYVFRVRAVNASGPGKPSDTSEPVLVEARPGTK
                     EISAGVDEEGNIYLGFDCQEMTDASQFTWCKAYEEIADEERFEVHTEGDHSKLYFKNP
                     DKIDIGTYSVSVSDTDGVSSSFVLDEEELERLMALSNEIKNPTIPLKSELAYEIFDKG
                     QVRFWLQAEHLSPDANFRFIINDREVSDSETHRIKCDRSTGMIEMVMDRFTIENEGTY
                     TVQIQDGKAKNQSSLVLIGDAFRAVLEEAEFQRKEFLRKQGPHFAEYLHWDVTEECEV
                     RLICKVANTKRETVFKWLKDDVLYETETPPPDLEKGICELLIPKLSKKDHGEYKATLK
                     DDRGQDVSVLEVAGKVYEDMILAMSRVCGASASPLKVLCTPEGIRLQCFMKYFTEEMK
                     VSWYHKEAKISSSEHMRIGGSEEMAWLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLS
                     GQAFDEAYAEFQQLKAAAFAEKNRGKVIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVV
                     WFKNDKDIELSEHFSVKVEQSKYVSLTIKGVTAEDSGKYSINVKNKYGGEKIDVTVSV
                     YKHGEKIPDISAPQQAKPKLIPASTSAD"
     exon            226..381
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            382..520
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            521..678
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            679..771
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            772..860
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            861..911
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            912..1076
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            1077..1238
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            1239..1380
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            1381..1580
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            1581..1634
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            1635..1762
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            1763..1946
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            1947..2121
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            2122..2243
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            2244..2431
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            2432..2558
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            2559..2737
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            2738..2852
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            2853..3009
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            3010..3116
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            3117..3161
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            3162..3298
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            3299..3443
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            3444..3503
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            3504..3571
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            3572..3688
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            3689..3776
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            3777..3815
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            3816..3921
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            3922..4085
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            4086..4122
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            4123..4145
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            4146..4201
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
     exon            4202..4513
                     /gene="Myom2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggctgcgag ccttcaggcc ttggggtctc tggaaccaaa gcctctttgt ctcccgaact
       61 ccaggggaac ctgatctttg aagaagaggt actcctcatc tttctgggaa tatccaagat
      121 gtccctggtt gtagtgcctt tctaccagaa aagacacaag cactttgacc agtcatatcg
      181 aaacatccaa accaggtacc tcctggaccg atatgcatcg aaaaagcaag cgtccagtca
      241 atcatcatcc cagaggtctc ttacggagag gtcctcttcg aagagagctt ccagtcagag
      301 ctccgctgag ggcatgacct gtaggctctg tgcaaagcgg atgagcgcat cagaagagga
      361 ggaagttgaa aatgaaaaca ggtaccggtc tctagcggct tcttacggag aagccaaaag
      421 gcagcgtttc ctcagtgagc tggcccagct ggaggagaac gtacaattgg cacggacaca
      481 ggctcggaac aagctggaca agtacttcct ggagcagacg gtggcagaca atctggcttt
      541 ggagagaagc tcatttgaag accggctgag cagggcccct gagatcctgg tgaggttaag
      601 gtcccacacc atctgggagc ggatgtctgt gaggctctgt ttcactgtac aaggattccc
      661 cactcctgtg gtgcaatggt acaaagacgg cagtctgatc tgccaggcag gggagccagg
      721 caagtaccgg attgagagca ggtacggagt gcacactctg gagatcaaca gggccgactt
      781 tgaggacaca gcgacctatt cagcagtagc aacgaatccc catggacaag tgtctaccaa
      841 tgctgcggtg gtggtgagaa ggtaccgagg agatgaggag ccctaccact cagtaggact
      901 cccaattgga ttgcctctct catctgtgat cccgtacaca cattttgatg tccagttttt
      961 ggagaaattc ggggtcacct tcagaagaga gggcgagacg gtcacactca agtgcacatt
     1021 attggtgaca ccagatctga agagggtaca gcctcgagcc gagtggtacc gggatgatgt
     1081 gctgctgaaa gagtccaagt ggaccaagat gttcttcgga gaaggccagg cctcactgtc
     1141 cttcagccac ctgaacaagg atgatgaggg gctttacacc ttgaggatcg tgtcccgggg
     1201 tggagtcagt gaccacagcg ctttcatgtt tgtcagagat gctgacccgc tggtcacagg
     1261 ggctcctggg gcacccatgg acctgcagtg ccatgatgcc aaccgagact atgttatcgt
     1321 gacttggaaa ccacccaaca ccactactga gagccccgtc attggctact tcattgacaa
     1381 atgtgaggtg ggaactaaca actgggttca gtgcaatgac gcaccggtaa agatctgcaa
     1441 gtaccccgtc accggacttt tcgaaggaag atcgtacgtg ttccgcgtga gggctgtcaa
     1501 taacgccggc ataagcaggc cttccaggat ctccgatgct gtggctgccc ttgaccctgt
     1561 ggacctcaga aggttgcaag cgattcattt ggaaggagag aaagaaatcg tcatctacca
     1621 ggatgacctt gaaggtgatg ttcagattcc aggacctccc accaatgtcc aggcttcaga
     1681 ggtcagcaga aactacgttg tcctcagctg ggatcctcct tctccccgtg gcaaggagcc
     1741 cttaatgtac ttcattgaga agtcggcagt tgggagtggc agctggcaga gggtcaatgc
     1801 ccagacagca gtgagatctc ctcggtatgc tgtctttgac ttggcggaag ggaagtccta
     1861 tgtgttccgg gttttgtcag ccaataagca tggcctgagt gacccatcag agataacacc
     1921 acctattcag gctcaggaca tgattgtggt tccctctgca cctggccggg tgcttgcttc
     1981 caggaataca aagacatctg tcgtggtcca gtgggacaga ccaaagcatg aagaagacct
     2041 gctgggctac tatgtggact gctgtgtggc gggaacaaac atgtgggaac catgtaacca
     2101 taaacccatt ggatataaca ggttcgtggt acacggctta accaccggtg agcagtacat
     2161 cttccgggtt aaggctgtga atgccgtggg gaccagcgag aactcccagg agtcagaggt
     2221 catcaaggtc caggcagccc tcactgtccc ctctcatccc tacgggatta cccttctcaa
     2281 ctgtgacggt cactccatga ccctgggctg gaaagtgccc aagttcagcg gcggctctgc
     2341 catcataggt tactacctgg acaagcggga agtgcatcat aagaactggc acgagatcaa
     2401 ctcttcgcct gtcaaagaga ggatcttaac ggtggaaggt ttgactgaag gctccttgta
     2461 tgagttcaaa atcgctgcta ccaacctggc tgggatcggg cagccatcgg atcccagtga
     2521 gcacttcaag tgtgaggcct ggacagcccc agaacctggt cccgcctatg acttgacgtt
     2581 ctgtgaggtc cgagacacat ctctggtcat actgtggaaa gccccggtgt actccggcag
     2641 cagtcctgtt tctggatatt ttgtggattt taaggaagag gattctgggg agtggaagac
     2701 caccagcgag gcagcaactc caaatcgcta cttaaaggtc tgtgacctgc atcaaggtaa
     2761 gacctatgta ttcagagttc gagcagtgaa tgccagtgga ccagggaagc cgtcagacac
     2821 atcggagcct gtgctcgtgg aggcccggcc aggcacaaag gagatcagtg ctggtgtgga
     2881 tgaggagggc aacatctacc ttgggtttga ctgccaggaa atgacagacg cctcgcagtt
     2941 cacctggtgc aaggcctatg aggagatcgc cgatgaggag cggttcgagg ttcacacaga
     3001 gggtgatcac tcaaagctgt acttcaagaa tccagataaa atagacatag ggacatattc
     3061 tgtatctgta agtgacacgg atggtgtgtc ttccagcttc gttttggatg aggaagaact
     3121 tgagcgtttg atggcgttga gcaatgagat aaagaatccc acaattcctc tgaaatcaga
     3181 attagcatat gagattttcg ataagggcca ggtccgattc tggctccagg cagagcacct
     3241 ctcacctgat gccaacttcc ggttcattat taatgacaga gaagtttctg acagtgagac
     3301 acacagaatt aaatgcgaca gatcgacagg catgattgag atggtcatgg atcggtttac
     3361 tattgaaaac gaagggacct acactgtgca gattcaagat ggaaaagcca agaatcagtc
     3421 ttcgctggtg ctcattggag atgcattcag ggctgtccta gaagaggctg aatttcaaag
     3481 gaaggaattt ctacggaaac aaggccctca ttttgctgag tatttgcact gggatgttac
     3541 tgaagagtgt gaagttcggc ttatctgtaa ggttgcaaac accaagaggg aaaccgtttt
     3601 caaatggctc aaggatgatg tcctttacga aaccgagaca ccaccgccgg acctggagaa
     3661 ggggatctgt gagctgctta tacccaagtt gtctaagaag gaccatggcg agtacaaagc
     3721 aaccttgaaa gatgacagag gtcaagatgt atctgtcttg gaagtagctg gcaaagtgta
     3781 cgaggacatg atcttggcaa tgagccgagt gtgtggagcc tctgcctcac ccctgaaggt
     3841 tctctgcact ccagagggca tccggcttca gtgcttcatg aagtatttca cagaggaaat
     3901 gaaggtcagc tggtaccaca aagaggctaa gatctcatcc agtgagcaca tgcggatcgg
     3961 aggaagcgag gagatggcct ggctgcagat ctgtgagccc acagagaagg acaaggggaa
     4021 atacactttc gagatcttcg atggcaaaga caaccaccaa cgctcactgg acctctctgg
     4081 gcaagccttc gatgaagcat atgccgagtt ccagcagctc aaggctgctg catttgctga
     4141 gaagaatcgt ggcaaggtga ttggcggttt gcccgacgtg gtgaccataa tggaaggcaa
     4201 gaccttgaac ctcacctgca cagtatttgg aaacccggac cctgaggtgg tctggtttaa
     4261 gaacgacaag gacattgagc taagcgagca cttctcggtg aaggtggagc agtccaagta
     4321 cgtcagcctg accattaagg gggtgactgc tgaggactcg ggcaagtaca gcatcaacgt
     4381 gaagaacaaa tacggaggag agaagatcga tgtcaccgtc agcgtgtaca aacacgggga
     4441 gaagatcccc gacatctcag ctccccagca ggccaaaccc aagcttatcc cagcttccac
     4501 ctcagctgat taa
//
