LOCUS       NM_001191584            5551 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus myomesin 1 (Myom1), mRNA.
ACCESSION   NM_001191584 XM_002730062
VERSION     NM_001191584.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5551)
  AUTHORS   Kravchenko,I.V., Furalyov,V.A., Chatziefthimiou,S., Wilmanns,M. and
            Popov,V.O.
  TITLE     Induction of insulin-like growth factor 1 splice forms by
            subfragments of myofibrillar proteins
  JOURNAL   Mol Cell Endocrinol 399, 69-77 (2015)
   PUBMED   25152160
REFERENCE   2  (bases 1 to 5551)
  AUTHORS   Pinotsis,N., Chatziefthimiou,S.D., Berkemeier,F., Beuron,F.,
            Mavridis,I.M., Konarev,P.V., Svergun,D.I., Morris,E., Rief,M. and
            Wilmanns,M.
  TITLE     Superhelical architecture of the myosin filament-linking protein
            myomesin with unusual elastic properties
  JOURNAL   PLoS Biol 10 (2), e1001261 (2012)
   PUBMED   22347812
REFERENCE   3  (bases 1 to 5551)
  AUTHORS   du Puy,L., Beqqali,A., van Tol,H.T., Monshouwer-Kloots,J.,
            Passier,R., Haagsman,H.P. and Roelen,B.A.
  TITLE     Sarcosin (Krp1) in skeletal muscle differentiation: gene expression
            profiling and knockdown experiments
  JOURNAL   Int J Dev Biol 56 (4), 301-309 (2012)
   PUBMED   22562206
REFERENCE   4  (bases 1 to 5551)
  AUTHORS   Gokhin,D.S., Lewis,R.A., McKeown,C.R., Nowak,R.B., Kim,N.E.,
            Littlefield,R.S., Lieber,R.L. and Fowler,V.M.
  TITLE     Tropomodulin isoforms regulate thin filament pointed-end capping
            and skeletal muscle physiology
  JOURNAL   J Cell Biol 189 (1), 95-109 (2010)
   PUBMED   20368620
REFERENCE   5  (bases 1 to 5551)
  AUTHORS   Beqqali,A., Monshouwer-Kloots,J., Monteiro,R., Welling,M.,
            Bakkers,J., Ehler,E., Verkleij,A., Mummery,C. and Passier,R.
  TITLE     CHAP is a newly identified Z-disc protein essential for heart and
            skeletal muscle function
  JOURNAL   J Cell Sci 123 (Pt 7), 1141-1150 (2010)
   PUBMED   20215401
REFERENCE   6  (bases 1 to 5551)
  AUTHORS   Hornemann,T., Kempa,S., Himmel,M., Hayess,K., Furst,D.O. and
            Wallimann,T.
  TITLE     Muscle-type creatine kinase interacts with central domains of the
            M-band proteins myomesin and M-protein
  JOURNAL   J Mol Biol 332 (4), 877-887 (2003)
   PUBMED   12972258
REFERENCE   7  (bases 1 to 5551)
  AUTHORS   Porter,J.D., Merriam,A.P., Gong,B., Kasturi,S., Zhou,X.,
            Hauser,K.F., Andrade,F.H. and Cheng,G.
  TITLE     Postnatal suppression of myomesin, muscle creatine kinase and the
            M-line in rat extraocular muscle
  JOURNAL   J Exp Biol 206 (Pt 17), 3101-3112 (2003)
   PUBMED   12878677
REFERENCE   8  (bases 1 to 5551)
  AUTHORS   Braun,A., Bordoy,R., Stanchi,F., Moser,M., Kostka,G. G, Ehler,E.,
            Brandau,O. and Fassler,R.
  TITLE     PINCH2 is a new five LIM domain protein, homologous to PINCHand
            localized to focal adhesions
  JOURNAL   Exp Cell Res 284 (2), 239-250 (2003)
   PUBMED   12651156
REFERENCE   9  (bases 1 to 5551)
  AUTHORS   Schiaffino,S. and Reggiani,C.
  TITLE     Molecular diversity of myofibrillar proteins: gene regulation and
            functional significance
  JOURNAL   Physiol Rev 76 (2), 371-423 (1996)
   PUBMED   8618961
  REMARK    Review article
REFERENCE   10 (bases 1 to 5551)
  AUTHORS   Vinkemeier,U., Obermann,W., Weber,K. and Furst,D.O.
  TITLE     The globular head domain of titin extends into the center of the
            sarcomeric M band. cDNA cloning, epitope mapping and immunoelectron
            microscopy of two titin-associated proteins
  JOURNAL   J Cell Sci 106 (Pt 1), 319-330 (1993)
   PUBMED   7505783
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            [WARNING] On Jul 25, 2024 this sequence was replaced by
            NM_001191584.2.
            
            On Jul 17, 2010 this sequence version replaced XM_002730062.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.50607.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06621351, SAMN09345238
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-320               JAXUCZ010000009.1  118367146-118367465
            321-461             JAXUCZ010000009.1  118380729-118380869
            462-783             JAXUCZ010000009.1  118382249-118382570
            784-941             JAXUCZ010000009.1  118383256-118383413
            942-1034            JAXUCZ010000009.1  118391016-118391108
            1035-1123           JAXUCZ010000009.1  118393340-118393428
            1124-1183           JAXUCZ010000009.1  118393534-118393593
            1184-1348           JAXUCZ010000009.1  118396799-118396963
            1349-1510           JAXUCZ010000009.1  118401344-118401505
            1511-1652           JAXUCZ010000009.1  118409806-118409947
            1653-1852           JAXUCZ010000009.1  118413283-118413482
            1853-1909           JAXUCZ010000009.1  118416111-118416167
            1910-2034           JAXUCZ010000009.1  118425240-118425364
            2035-2218           JAXUCZ010000009.1  118430662-118430845
            2219-2393           JAXUCZ010000009.1  118431160-118431334
            2394-2515           JAXUCZ010000009.1  118433567-118433688
            2516-2806           JAXUCZ010000009.1  118434930-118435220
            2807-3003           JAXUCZ010000009.1  118437068-118437264
            3004-3130           JAXUCZ010000009.1  118442573-118442699
            3131-3315           JAXUCZ010000009.1  118445013-118445197
            3316-3430           JAXUCZ010000009.1  118447869-118447983
            3431-3587           JAXUCZ010000009.1  118455050-118455206
            3588-3694           JAXUCZ010000009.1  118456059-118456165
            3695-3739           JAXUCZ010000009.1  118456276-118456320
            3740-3876           JAXUCZ010000009.1  118460490-118460626
            3877-4021           JAXUCZ010000009.1  118461113-118461257
            4022-4081           JAXUCZ010000009.1  118462866-118462925
            4082-4149           JAXUCZ010000009.1  118463178-118463245
            4150-4263           JAXUCZ010000009.1  118466902-118467015
            4264-4351           JAXUCZ010000009.1  118467846-118467933
            4352-4390           JAXUCZ010000009.1  118468843-118468881
            4391-4496           JAXUCZ010000009.1  118468977-118469082
            4497-4660           JAXUCZ010000009.1  118476622-118476785
            4661-4697           JAXUCZ010000009.1  118480152-118480188
            4698-4720           JAXUCZ010000009.1  118480575-118480597
            4721-4776           JAXUCZ010000009.1  118481815-118481870
            4777-5551           JAXUCZ010000009.1  118485180-118485954
FEATURES             Location/Qualifiers
     source          1..5551
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q38"
     gene            1..5551
                     /gene="Myom1"
                     /note="myomesin 1"
                     /db_xref="GeneID:316740"
                     /db_xref="RGD:631436"
     CDS             1..5070
                     /gene="Myom1"
                     /note="myomesin 1 (skelemin) 185kDa"
                     /codon_start=1
                     /product="myomesin-1"
                     /protein_id="NP_001178513.1"
                     /db_xref="GeneID:316740"
                     /db_xref="RGD:631436"
                     /translation="MSLPFYQRSHQHYDLSYRNKDLHTTMSHYQQEKKRSAVYTHGST
                     AYSSRSSAAHRQESEALRQASAASYQQQASKAYSLGTSSSQHYQGSEVSRKTASSYDY
                     GYSHGLTDSSLLLEDYSSRLSPQTKRAKRSLLSGEETGNLSGNYMVPIYSGRQVHISG
                     IRDSEEERIKEAAAYIAQRTLLESEEAIMASKQSTASKQSTASKQSIASKQSTASKQS
                     TASKQSTASKQATSTFQQEETFERKSRNISIREKAEELSLRKTLEETQAYHGKLNEDH
                     LLHAPEFIIKPRSHTVWEKENVKLHCSVAGWPEPRLTWYKNQVPINVHANPEKYIIES
                     RYGMHTLEISKCDFEDTAQYRASAMNVQGEVSAYASVVVKRYKGELDDSLLRGGVSMP
                     LSFAVTPYGYASKFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHVQPEVQWYRNG
                     APVSPSKWVQPHWSGDRATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAE
                     IEGAPAAPLDVVSLDANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDTWSQCNDTP
                     VKFARFPVTGLIEGRSYIFRVRAVNKTGIGLPSRVSEPVAALDPAEKARLKSRPSAPW
                     TGQIIVTEEEPTEGVIPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCDVG
                     TENWQRVNTELPVKSPRFALFDLVEGKSYRFRVRCSNSAGVGEPSESTEVTVVGDKLD
                     IPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIESSVVGSGQWEPCNNNPVKGSR
                     FTCHGLTTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVWPQLSDTPGG
                     LTDSGGAMSGASPPTSQKDALPSSKPNKPSPPSSPSNRGQKEVSKVNGSVQEELSPPS
                     MEVASKEQSKSGPPEKKKDPVAVPSPPYDITCLESFRDSMVLGWKQPDKTGGAEITGY
                     YVNYREVVGGVPGKWREANIKAVSDAAYKISELKENTVYQFQVSAMNIAGLGAPSAVS
                     ECFKCEEWTIAVPGPPHSLKLSEVRKNSLVLQWKPPVYSGRTPVTGYFVDLKEASAKD
                     DQWRGLNEAAIPNKYLRVQGLKEGISYVFRVRAINQAGVGKPSDLAGPVVAETRPGTK
                     EVVVNVDDDGVISLNFECDQMTPKSEFVWSKDYVPSEDSPRLEVESKGNKTKMVFKDL
                     GPDDLGTYSCDVTDTDGIASSYLIDEEEMKRLLALSQEHKFPTVPTKSELAVEILEKG
                     QVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTY
                     TFQIQDGKATGHSTLVLIGDVYKKLQKEAEFQRQEWIRKQGPHFAEYLSWEVTGECNV
                     LLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFSKKDAGFYEVILKD
                     DRGKDKSRLKLVDEAFQDLMTEVCRKIALSATDLKIQSTAEGIRLYSFVCYYLDDLKV
                     NWSHNGTGIKYTDRVKSGVTGEQIWLQINEPTQNDKGKYVMELFDGKTGHQKSVDLSG
                     QAFDEAFAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPTPEVSW
                     LKNEKPLTSDDHCSLKFEAGKTAFFTISGVSTADSGKYGLVVKNKYGSETSDFTVSVF
                     IPEEEARKGASEPPKGNQKSK"
     exon            1..320
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            321..461
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            462..783
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            784..941
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            942..1034
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            1035..1123
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            1124..1183
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            1184..1348
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            1349..1510
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            1511..1652
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            1653..1852
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            1853..1909
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            1910..2034
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            2035..2218
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            2219..2393
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            2394..2515
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            2516..2806
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            2807..3003
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            3004..3130
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            3131..3315
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            3316..3430
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            3431..3587
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            3588..3694
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            3695..3739
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            3740..3876
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            3877..4021
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            4022..4081
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            4082..4149
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            4150..4263
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            4264..4351
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            4352..4390
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            4391..4496
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            4497..4660
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            4661..4697
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            4698..4720
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            4721..4776
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
     exon            4777..5551
                     /gene="Myom1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgtctttgc ctttttatca gaggtcccac cagcactatg atctcagtta ccgtaacaag
       61 gacctccata ccaccatgag ccactaccaa caggagaaga agcgctctgc ggtctacacc
      121 catggctcca ctgcctacag cagccgttcc tccgcagcac accgccagga gtcagaggcc
      181 ttgaggcaag catcagccgc ctcctaccag cagcaggcct cgaaggccta cagtcttgga
      241 acatcgtcat cccagcatta tcaagggtct gaagtcagtc ggaagacagc ctcttcgtat
      301 gattacggct attcccatgg actcacagat tccagtctgc tattagaaga ttattcatcc
      361 aggttgagtc ctcaaaccaa gagagccaag cggagccttc tgtcgggaga ggagactgga
      421 aacctgtcag gcaactacat ggtgcctatt tactctggac ggcaagtgca catcagtgga
      481 atcagagact cagaagaaga aagaattaaa gaagctgctg cttacatagc tcagaggact
      541 cttcttgaga gtgaggaagc aatcatggcc tccaagcaga gcacagcctc caagcagagc
      601 acagcctcca aacagagcat agcctccaaa cagagcacag cctccaaaca gagcacagcc
      661 tccaaacaga gcacagcctc caagcaggcc acatccacct ttcaacaaga ggaaacattt
      721 gaaaggaagt caaggaacat ttcaattcga gaaaaggcag aagagctgtc gctgaggaaa
      781 actttagaag agacccaagc ataccacgga aaactaaatg aagaccatct ccttcacgct
      841 cccgaattta tcatcaaacc tcgttctcac acagtctggg agaaagagaa cgtgaagttg
      901 cactgctccg tagcaggctg gccagaaccc cgcctcacgt ggtataaaaa ccaggtgcct
      961 ataaatgtcc atgcaaaccc agaaaagtac atcattgaaa gtcgatatgg aatgcatact
     1021 cttgagatca gcaagtgtga cttcgaagac acggctcagt accgggcctc ggcgatgaat
     1081 gttcaaggag aggtctcagc atatgcctcg gtggtggtga agagatataa aggagaactg
     1141 gacgattctc tcctccgtgg tggggtttcc atgcctctca gctttgctgt gaccccttac
     1201 ggctatgcat ccaagtttga gatccacttt gatgacaagt ttgatgtgtc ttttgggaga
     1261 gaaggagaga ccatgagtct gggctgccgt gtggtcatca ctcctgaaat taaacacgtc
     1321 cagccagagg tccagtggta tagaaatgga gcacctgttt ctccctcaaa atgggtgcag
     1381 ccacactgga gtggagaccg ggcaacactc acattctctc acctcaacaa agaagatgaa
     1441 ggtctctaca caatccgtgt gcgaatggga gagtattatg aacagtacag tgcttacgtc
     1501 tttgttcgag atgctgatgc agagatcgaa ggagcccctg ctgcaccctt ggatgtggtg
     1561 tctttggatg ctaacaaaga ttacatcatc atctcttgga agcagccagc tgtggatgga
     1621 gggagcccta tcctgggata ctttattgat aagtgtgagg tgggcacaga cacctggtct
     1681 cagtgcaacg acacgcctgt gaagtttgct cggtttccag tcactggttt gatagaaggt
     1741 cgttcctaca tattccgagt ccgtgctgtg aataaaactg gaataggctt gccatctcga
     1801 gtttctgagc ccgtggctgc tctggaccca gctgagaaag ccagacttaa aagtcgtcct
     1861 tcagcaccct ggactggaca gatcattgtc actgaagagg aacctacaga gggtgtcatt
     1921 cctgggcccc ccacagacct ctctgtcacc gaggccaccc ggagttatgt agtgctgagc
     1981 tggaaacccc ctgggcagcg aggccatgaa ggcatcatgt actttgtaga aaagtgtgat
     2041 gtgggaacag aaaactggca gcgtgtcaac acagaactcc cagtgaagtc tcctcgcttt
     2101 gctctgtttg acctggtgga ggggaaatct taccgcttcc gtgtccgctg ctcaaattca
     2161 gcaggagttg gtgaaccctc agagtcaacc gaagtgaccg tcgtagggga caaacttgat
     2221 atccccaaag cccctggcaa aatcatccca agtagaaata cagatacctc agtggtggtt
     2281 tcttgggagg agtccaagga tgccaaagag ctggttgggt actacatcga gtccagtgtt
     2341 gttggctctg gccagtggga accctgcaac aacaacccag tgaagggctc acgatttact
     2401 tgccacggac tgacaactgg tcagagctat attttccggg tcagagcagt gaacgcagct
     2461 ggacttagtg aatactccca ggattcggaa gctattgaag tcaaagctgc tattggggga
     2521 ggagtgtctc cagatgtgtg gcctcaactg agtgatacgc ctggtggact aacagactcc
     2581 gggggggcca tgagtggagc ctccccgcca acctctcaga aagatgcttt gcccagtagc
     2641 aaacctaata aaccttcacc acccagtagc ccttccaacc ggggccagaa agaagtaagt
     2701 aaagtaaatg gatcagttca ggaggagctc agcccgccat ccatggaggt agcttctaag
     2761 gagcaaagta aatctgggcc cccggaaaag aagaaggatc cagtagcggt gccatctcca
     2821 ccctatgaca tcacttgtct tgaaagtttt cgagactcaa tggttcttgg atggaagcag
     2881 ccagataaga ccggtggggc agagattacg ggctattacg tgaactatcg tgaggtggtt
     2941 ggcggggtac caggaaaatg gagggaagcc aacatcaagg ctgtcagcga tgcagcctac
     3001 aagattagcg aattgaagga aaacacagtg taccagttcc aagtgtcagc aatgaacatc
     3061 gcagggctgg gagcgccctc tgcagtgagc gagtgcttca aatgtgaaga atggaccatt
     3121 gctgtcccgg gaccaccaca cagcctgaag ctcagtgaag tcaggaagaa ctccctggtt
     3181 ctgcagtgga agcctccggt ctactcaggc cggactccag tcacgggtta ctttgtggac
     3241 ctgaaggaag ccagtgccaa agatgaccaa tggcgaggac ttaatgaggc agccattcca
     3301 aacaagtacc tgagggtgca aggcctcaaa gagggtatca gctacgtgtt ccgtgtgcgg
     3361 gccatcaacc aggcgggtgt tgggaagcct tctgatctcg ctggacctgt tgtggctgaa
     3421 actcgtccag gtaccaaaga ggttgttgtg aatgtggatg atgatggagt catttccttg
     3481 aactttgaat gtgatcagat gactcccaag tcagaattcg tctggtccaa agattatgtc
     3541 ccttctgaag actctccacg attagaagtt gaaagcaaag gcaataagac aaaaatggtc
     3601 tttaaagacc tcgggccaga tgacttgggc acctattctt gtgatgtaac ggacactgac
     3661 gggatagcgt caagctactt gatagacgaa gaagagatga aacgtctgct cgccctcagc
     3721 caggagcaca agttcccgac tgtcccgact aagtcagagc tggcggttga aattttggag
     3781 aaaggtcagg tccggttttg gatgcaggct gagaagctgt ctggcaatgc caaagtcaac
     3841 tacatattta acgagaagga aatttttgag gggccgaaat acaagatgca catcgaccga
     3901 aacactggca tcatcgaaat gttcatggag aagctgcagg atgaggatga agggacgtac
     3961 acattccaga ttcaggatgg aaaagcaact ggccattcta cccttgttct cattggagac
     4021 gtttataaga agctacagaa agaagctgaa ttccagcgac aagaatggat caggaaacaa
     4081 ggcccacact tcgctgagta tttgagctgg gaagtgactg gcgaatgtaa tgtcctgttg
     4141 aagtgcaagg tggcaaatat taaaaaagag actcacatcg tttggtacaa agatgagcgg
     4201 gagatctcag tggacgagaa acatgacttt aaggacggca tttgtaccct gctcatcaca
     4261 gagttttcca agaaagatgc tggattttat gaagttatcc tgaaagatga ccggggaaaa
     4321 gataagagca gattgaaact cgtggacgaa gccttccaag acttgatgac tgaagtatgc
     4381 aggaagatag ctttatccgc cacagacctg aaaatccaga gcacagcaga gggcatccgg
     4441 ctgtactcct ttgtctgtta ctacctggat gacttgaaag ttaactggtc ccacaatggg
     4501 actgggatta agtacacaga cagagtcaag agtggggtca ccggggagca gatctggctg
     4561 cagatcaatg agcccactca gaatgataaa gggaaatacg taatggagct ctttgatggc
     4621 aagactggac accagaagtc ggtggatctc tctggacaag catttgatga agcctttgct
     4681 gaattccaga ggttaaaaca agctgccatt gccgagaaaa atcgggctcg ggtgctgggc
     4741 ggtctcccgg atgttgtcac cattcaggag ggcaaggcac tcaatctcac ctgcaatgtg
     4801 tggggtgacc caacccctga ggtgtcctgg ctgaaaaatg agaagccgct gacctccgac
     4861 gaccactgca gcctcaagtt tgaggctggg aagacagcct tcttcaccat ctcaggcgtg
     4921 agcacggcag actccggcaa gtacgggctg gtggtgaaga acaaatacgg ctcggagacc
     4981 agtgacttca ccgtcagtgt gttcatcccc gaggaggagg caaggaaggg agcatcagag
     5041 cccccaaagg gcaaccagaa gtccaagtga gcggagactg ggggagttat gaggagagcc
     5101 agggccagct ggccacccac cgcgctgctg ttgtgaaaat gattcggtta gagatgagga
     5161 gatcctcctg gtgtctccct gctttgtgct gacttaggag gaaaccatca aatctcttac
     5221 tcctataggc accaataaag gacaatttaa gggtttttaa tctacaattt ctgtagtaaa
     5281 aaaatacatt aggaaatgat ttcaaggaag aaggccagag aatgtcgtag tggtgctaaa
     5341 agagagcaga agcgaggccg agttggaagc tgatgaagta agttcttagg gattgtgtct
     5401 acatctggca ctctgtcaga acagaggcac actgctgtgg gcttgagtgt ggtgggtcac
     5461 tgttactgtg gtgatggtgc atttctgatg gcagccttgg gaactggcct cccccagtgt
     5521 gaataaagtc tttcccctca tgtctctcca a
//
