LOCUS       NM_001354115            6748 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus myoferlin (Myof), mRNA.
ACCESSION   NM_001354115 XM_006231326
VERSION     NM_001354115.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6748)
  AUTHORS   Demonbreun,A.R., Rossi,A.E., Alvarez,M.G., Swanson,K.E.,
            Deveaux,H.K., Earley,J.U., Hadhazy,M., Vohra,R., Walter,G.A.,
            Pytel,P. and McNally,E.M.
  TITLE     Dysferlin and myoferlin regulate transverse tubule formation and
            glycerol sensitivity
  JOURNAL   Am J Pathol 184 (1), 248-259 (2014)
   PUBMED   24177035
REFERENCE   2  (bases 1 to 6748)
  AUTHORS   Stamer,W.D., Hoffman,E.A., Luther,J.M., Hachey,D.L. and Schey,K.L.
  TITLE     Protein profile of exosomes from trabecular meshwork cells
  JOURNAL   J Proteomics 74 (6), 796-804 (2011)
   PUBMED   21362503
REFERENCE   3  (bases 1 to 6748)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   4  (bases 1 to 6748)
  AUTHORS   Fujimoto,M., Oshima,K., Shinkawa,T., Wang,B.B., Inouye,S.,
            Hayashida,N., Takii,R. and Nakai,A.
  TITLE     Analysis of HSF4 binding regions reveals its necessity for gene
            regulation during development and heat shock response in mouse
            lenses
  JOURNAL   J Biol Chem 283 (44), 29961-29970 (2008)
   PUBMED   18755693
REFERENCE   5  (bases 1 to 6748)
  AUTHORS   Bernatchez,P.N., Acevedo,L., Fernandez-Hernando,C., Murata,T.,
            Chalouni,C., Kim,J., Erdjument-Bromage,H., Shah,V., Gratton,J.P.,
            McNally,E.M., Tempst,P. and Sessa,W.C.
  TITLE     Myoferlin regulates vascular endothelial growth factor receptor-2
            stability and function
  JOURNAL   J Biol Chem 282 (42), 30745-30753 (2007)
   PUBMED   17702744
REFERENCE   6  (bases 1 to 6748)
  AUTHORS   Davis,D.B., Doherty,K.R., Delmonte,A.J. and McNally,E.M.
  TITLE     Calcium-sensitive phospholipid binding properties of normal and
            mutant ferlin C2 domains
  JOURNAL   J Biol Chem 277 (25), 22883-22888 (2002)
   PUBMED   11959863
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Aug 5, 2017 this sequence version replaced XM_006231326.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760386, SAMEA5760393
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-174               JAXUCZ010000001.1  245234595-245234768 c
            175-230             JAXUCZ010000001.1  245212162-245212217 c
            231-322             JAXUCZ010000001.1  245210577-245210668 c
            323-431             JAXUCZ010000001.1  245191216-245191324 c
            432-519             JAXUCZ010000001.1  245187880-245187967 c
            520-686             JAXUCZ010000001.1  245180389-245180555 c
            687-815             JAXUCZ010000001.1  245179740-245179868 c
            816-878             JAXUCZ010000001.1  245177055-245177117 c
            879-929             JAXUCZ010000001.1  245176930-245176980 c
            930-960             JAXUCZ010000001.1  245175311-245175341 c
            961-1076            JAXUCZ010000001.1  245174746-245174861 c
            1077-1203           JAXUCZ010000001.1  245173930-245174056 c
            1204-1307           JAXUCZ010000001.1  245170786-245170889 c
            1308-1376           JAXUCZ010000001.1  245167393-245167461 c
            1377-1420           JAXUCZ010000001.1  245167076-245167119 c
            1421-1503           JAXUCZ010000001.1  245164558-245164640 c
            1504-1628           JAXUCZ010000001.1  245160548-245160672 c
            1629-1745           JAXUCZ010000001.1  245159287-245159403 c
            1746-1923           JAXUCZ010000001.1  245153116-245153293 c
            1924-2048           JAXUCZ010000001.1  245151711-245151835 c
            2049-2155           JAXUCZ010000001.1  245148483-245148589 c
            2156-2348           JAXUCZ010000001.1  245146262-245146454 c
            2349-2504           JAXUCZ010000001.1  245144796-245144951 c
            2505-2636           JAXUCZ010000001.1  245141346-245141477 c
            2637-2800           JAXUCZ010000001.1  245139556-245139719 c
            2801-2915           JAXUCZ010000001.1  245135448-245135562 c
            2916-3021           JAXUCZ010000001.1  245133005-245133110 c
            3022-3167           JAXUCZ010000001.1  245131623-245131768 c
            3168-3341           JAXUCZ010000001.1  245129295-245129468 c
            3342-3450           JAXUCZ010000001.1  245128710-245128818 c
            3451-3528           JAXUCZ010000001.1  245127015-245127092 c
            3529-3710           JAXUCZ010000001.1  245124931-245125112 c
            3711-3869           JAXUCZ010000001.1  245124694-245124852 c
            3870-3968           JAXUCZ010000001.1  245124480-245124578 c
            3969-4130           JAXUCZ010000001.1  245123499-245123660 c
            4131-4296           JAXUCZ010000001.1  245121177-245121342 c
            4297-4373           JAXUCZ010000001.1  245118181-245118257 c
            4374-4385           JAXUCZ010000001.1  245114426-245114437 c
            4386-4484           JAXUCZ010000001.1  245111974-245112072 c
            4485-4610           JAXUCZ010000001.1  245110361-245110486 c
            4611-4766           JAXUCZ010000001.1  245108719-245108874 c
            4767-4858           JAXUCZ010000001.1  245108102-245108193 c
            4859-5029           JAXUCZ010000001.1  245103631-245103801 c
            5030-5178           JAXUCZ010000001.1  245102867-245103015 c
            5179-5318           JAXUCZ010000001.1  245100522-245100661 c
            5319-5407           JAXUCZ010000001.1  245098467-245098555 c
            5408-5503           JAXUCZ010000001.1  245098285-245098380 c
            5504-5645           JAXUCZ010000001.1  245094911-245095052 c
            5646-5745           JAXUCZ010000001.1  245092485-245092584 c
            5746-5936           JAXUCZ010000001.1  245090882-245091072 c
            5937-6046           JAXUCZ010000001.1  245089020-245089129 c
            6047-6194           JAXUCZ010000001.1  245088470-245088617 c
            6195-6748           JAXUCZ010000001.1  245086109-245086662 c
FEATURES             Location/Qualifiers
     source          1..6748
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q53"
     gene            1..6748
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /note="myoferlin"
                     /db_xref="GeneID:309499"
                     /db_xref="RGD:1564216"
     exon            1..174
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     CDS             87..6233
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /note="fer-1-like 3, myoferlin"
                     /codon_start=1
                     /product="myoferlin"
                     /protein_id="NP_001341044.1"
                     /db_xref="GeneID:309499"
                     /db_xref="RGD:1564216"
                     /translation="MLRVIVESATNIPKTKFGKPDPIVSVIFKDEKKKTKKVDNELNP
                     VWNEILEFDLRGIPLDSSSSLVIVVKDFETIGQNKLIGTATVSLKDLIGDQNRSLPYK
                     QISLLNEKGQDTGATIDLVIGYTPPSAPYPNDPSGTSVTGVGEEEEEDQGDEDRVDGM
                     VRGPGPKGPSGTMSEAQLARRITKGKSSRRMLSNKPQDFQIRVRVIEGRQLCGNNIRP
                     VVKVHVCGQTHRTRIKRGNNPFFDELFFYNVHITPSELMDEIISIRVYNSHSLRADSL
                     MGEFKIDVGFVYDEPGHAVMRKWLLLNDPEDTSSGAKGYMKVSMFVLGTGDEPPSEKR
                     DRDNDSDDVESNLLLPAGIALRWVTFLLKIYRAEDIPQMDDAFSQTVKEIFGGNADKK
                     NLVDPFVEVSFAGKKVCTNIIERNANPEWNQVVNLQIKFPSMCEKIKLTVYDWDRLTK
                     NDVVGTTYLYLSKIAASGGEVEANTGETEVGFVPTFGPCYLNLYGSPREYTGFPDPYD
                     ELNSGKGEGVAYRGRILVELNTFLEKKPPEKKLEPISNDDLLVVEKYQRRRKYSLSAV
                     FHSATMLQDVGEAIQFEVSIGNYGNKFDATCKPLASTTQYSRAVFDGNYYYYLPWART
                     KPVVTLTSYWEDISHRLDAVNTLLVMAERLQSNIEAVKSGIQGKIPTNQLAELWLKLI
                     DEVIEDTRYTLPVTEGKANVTVLDTQIRKLRLRFLSQIHEAALRMRSEATDVKSTLLE
                     IEEWLDKLMQLTEEPQNSMPDIIIWMIRGEKRLAYARIPAHQVLYSTSGGNASGKYCG
                     KTQTILLKYPQEKNNGPKVPVELRVNIWLGLSAVEKKFNSFAEGTFTVFAEMYENQAL
                     VFGKWGTSGLVGRHKFSDVTGKIKLKREFFLPPKGWEWEGDWVVDPERSLLTEADAGH
                     TEFTDEVYQNETRYPGGEWKQAEDTYTDANGDKAASPNEMTCPPGWEWEDDAWTYDIN
                     RAVDEKGWEYGITIPPDNKPKSWVAAEKMYHTHRRRRLVRKRKKDLTQTASSTARAME
                     ELEDREGWEYASLIGWKFHWKQRSSDTFRRRRWRRKMAPSETHGAAAIFKLEGALGAD
                     TTEDGDEKSLEKQKHSATTVFGANTPIVSCNFDRVYIYHLRCYIYQARNLMALDKDSF
                     SDPYAHVSFLHRSKTTEIIHSTLNPTWDQTIIFDDVEIFGEPQTVLQNPPKVIIELFD
                     SDQVGKDEFLGRSICSPLVKLNSETDTTPKLLWHPVMNGDKACGDVLVTAELILRNKD
                     GSNLPILPSQRAPNLYMVPQGIRPVVQLTAIEILAWGLRNMKNYQMASITSPSLVVEC
                     GGERVESVVIKSLKKTPNFPSSVLFMKVFLPKEELYMPPLVIKVIDHRQFGRKPVVGQ
                     CTIDHLDRFRCDPYAGKEDIVPQLKASLMSAPPCRDVIIEIEDTKPLLASKLSEKEEE
                     IVDWWSKFYASSGEHEKCGQYIQKGYSKLKIYDCELEDVADFEGLTDFSDTFKLYRGK
                     SDENEDPSVVGEFKGSFRIYPLPDDPSVPAPPRQFRELPDSVPQECTVRIYIVQGLQL
                     QPQDNNGLCDPYIKITLGKKVIEDRDHYIPNTINPVFGRMYELSCYLPQEKDLKISVY
                     DYDTFTRDEKVGETTIDLENRFLSRFGSHCGIPEQYCVSGVNTWRDQLRPTQLLQNVA
                     RFKGFPPPVLSEDGSRIQYGGRDYHLDEFEANKILHQHLGAPEERLALHILRTQGLVP
                     EHVETRTLHSTFQPNISQGKLQMWVDVFPKSLGPPGPPFNITPRKAKTYYLRVIIWNT
                     RDVILDEKSITGEDMSDIYVKGWISGSEENKQKTDVHYRSLDGEGNFNWRFVFPFDYL
                     PAEQLCIVAKKEHFWSIDQTEFRVPPRLIIQIWDNDKFSLDDYLGFLELDLHRTIIPA
                     KTSEKCSLDMIPDLKAMDPLKAKTASLFEQKSMKGWWPCYADKDGSRVMAGKVEMTLE
                     VLNEREADERPAGKGRSEPNMNPKLDPPNRPETSFLWFTNPCKTMRFIVWRRFKWVII
                     GLLLLLILLLFVAVLLYSLPNYLSMKIVRPNA"
     exon            175..230
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            231..322
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            323..431
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            432..519
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            520..686
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            687..815
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            816..878
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            879..929
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            930..960
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            961..1076
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            1077..1203
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            1204..1307
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            1308..1376
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            1377..1420
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            1421..1503
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            1504..1628
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            1629..1745
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            1746..1923
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            1924..2048
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            2049..2155
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            2156..2348
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            2349..2504
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            2505..2636
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            2637..2800
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            2801..2915
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            2916..3021
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            3022..3167
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            3168..3341
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            3342..3450
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            3451..3528
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            3529..3710
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            3711..3869
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            3870..3968
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            3969..4130
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            4131..4296
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            4297..4373
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            4374..4385
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            4386..4484
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            4485..4610
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            4611..4766
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            4767..4858
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            4859..5029
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            5030..5178
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            5179..5318
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            5319..5407
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            5408..5503
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            5504..5645
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            5646..5745
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            5746..5936
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            5937..6046
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            6047..6194
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
     exon            6195..6748
                     /gene="Myof"
                     /gene_synonym="Fer1l3; RGD1564216"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagacatcct cctcccaggg cggagggccc agcgccagca ccgcgtctag tccgctcttg
       61 gctgcaactt gctttctcca agagccatgc ttcgagtgat tgtggaatct gctactaaca
      121 tccctaaaac gaaatttggg aaaccggatc ctatcgtttc tgtcattttt aaggatgaga
      181 aaaagaaaac aaagaaagtt gataatgaac tcaaccctgt ctggaatgag attttggaat
      241 ttgacttgag ggggatacca ctggactctt catcttccct ggtgattgtt gtcaaagatt
      301 ttgagacgat tggacaaaat aaattaattg gcacagcaac tgtgtccctg aaggacctga
      361 tcggggacca gaacagatct ctgccctaca aacagatctc cctgctaaac gagaagggac
      421 aagacacggg ggccaccatt gacctggtga ttggctatac cccaccttca gctccatatc
      481 caaatgatcc gagtgggacc agtgtgacag gcgtgggaga agaagaggaa gaagaccagg
      541 gggatgaaga cagggtagat ggcatggtca gaggccctgg acccaagggg ccatctggga
      601 caatgtcaga agctcagctt gctcggagga tcaccaaagg gaagagcagc cggaggatgc
      661 tgtccaacaa gccacaggat ttccagatcc gtgtcagagt gattgaaggc cgtcagttat
      721 gcggcaacaa cataaggcct gtggtgaaag ttcacgtctg tggtcagaca caccgcacga
      781 gaatcaagag agggaacaat ccattttttg atgagttatt tttctacaat gtgcacatca
      841 caccctctga actcatggat gagatcatca gcatccgggt ttataattcc cactctctga
      901 gggcagatag tctgatgggg gaatttaaga ttgatgttgg atttgtttac gatgaacctg
      961 gccatgctgt catgaggaaa tggctccttc tcaatgaccc agaagacacc agctcaggtg
     1021 caaaggggta catgaaagtc agcatgtttg tcctgggaac cggagacgaa cccccatctg
     1081 agaaacgaga ccgggacaat gacagtgatg acgtcgagag caacttgtta cttccagctg
     1141 gcattgccct ccggtgggta accttcttgc tgaagatcta ccgagctgag gacatccccc
     1201 agatggatga tgccttctca cagacagtga aggaaatatt tggtggcaat gctgataaaa
     1261 aaaatctcgt ggaccctttc gtagaggtct cctttgctgg gaaaaaggtg tgtacaaata
     1321 ttattgagag aaatgcaaac cccgaatgga atcaagttgt caatcttcag atcaagtttc
     1381 cttccatgtg tgaaaaaata aaactaacag tgtatgactg ggaccggctt accaaaaatg
     1441 atgtagttgg gacgacatac ctgtacctct ctaaaattgc tgcctctggg ggagaagtgg
     1501 aagcaaatac aggagagact gaggtgggtt tcgtcccaac atttggacct tgttatttga
     1561 acctttatgg aagccccaga gagtacacag gatttccaga tccctacgat gagctgaatt
     1621 caggaaaggg agaaggggtg gcctacagag gcaggatctt ggttgaactg aacacgttcc
     1681 ttgaaaagaa accaccagaa aagaagcttg agcccatttc aaatgatgac cttctggttg
     1741 ttgagaaata ccagcgacgg cggaagtaca gcctgtcggc cgtgttccat tcagccacca
     1801 tgttgcaaga tgttggcgag gccattcagt ttgaagtcag cattgggaac tatggcaaca
     1861 agtttgatgc aacctgtaaa cctctggcat caacaactca atacagccgt gcagtatttg
     1921 atgggaacta ctattactat ttaccttggg cccgcacaaa gcctgttgtc accctgactt
     1981 cctactggga ggatattagt catcgcctgg atgcagtgaa cactctccta gtcatggcag
     2041 aacggctgca atcaaacatc gaggctgtaa aatcaggaat ccaaggtaaa attcccacaa
     2101 accagttggc agagctgtgg ctgaagctaa tagacgaagt tatagaagac acaagataca
     2161 ccttgcctgt cactgaagga aaagccaacg tcacagttct ggatactcag atccgaaagt
     2221 tgcggctgag gtttctctcg cagatacacg aggcggctct gaggatgaga tctgaagcca
     2281 cggatgtgaa atccaccttg ctggagatcg aggagtggct tgataaatta atgcaactta
     2341 ctgaagagcc tcagaacagt atgcccgaca tcatcatctg gatgatccgc ggggagaaaa
     2401 gactggctta tgcacggatt cctgcccacc aagtcttata ctccaccagt ggtgggaacg
     2461 cctccggaaa atactgtggg aaaacccaaa ccatccttct gaagtatcca caagaaaaga
     2521 acaatgggcc caaagtgcct gtggaattgc gagtgaacat ctggctgggt ttaagcgccg
     2581 tggaaaagaa gttcaatagc ttcgctgaag gcacattcac cgtctttgct gaaatgtatg
     2641 aaaaccaagc cctcgtgttt gggaagtggg gcacctctgg actggtggga cgccataaat
     2701 tctctgatgt cacaggaaaa ataaaactca aaagagaatt ctttttacct cccaaaggct
     2761 gggaatggga aggagactgg gtagttgacc ctgaacgaag cctcctgact gaggctgatg
     2821 caggtcacac agagttcact gatgaagtgt accagaacga gactcgctat cctggaggcg
     2881 agtggaagca ggcagaggac acctataccg atgcgaatgg agataaagca gcatcaccca
     2941 atgagatgac ttgccctccg ggttgggagt gggaagatga cgcatggaca tatgacataa
     3001 atcgagcagt ggacgagaaa ggctgggagt atggaattac cattcctcct gacaataagc
     3061 ccaaatcctg ggtcgcagca gagaagatgt atcacactca caggcggcgg agactggtcc
     3121 gaaagcgcaa gaaagatttg acacagacgg cttccagcac tgcgagggcc atggaagaac
     3181 ttgaagaccg ggagggctgg gaatacgcct cgttaattgg ctggaaattc cactggaaac
     3241 agcgcagttc agataccttt cgccgcaggc gctggaggag aaaaatggct ccttcagaga
     3301 cacatggcgc agcggccatc tttaaacttg aaggtgccct tggggcagac accacagagg
     3361 atggagatga aaagagccta gagaagcaga agcacagtgc caccactgtg tttggagcaa
     3421 acacacccat tgtttcctgt aatttcgaca gagtctacat ctaccaccta cgctgctaca
     3481 tttatcaagc ccggaacctc atggctttgg acaaagacag cttttcagac ccgtatgctc
     3541 atgtctcctt cctccatcga agcaaaacca ctgagatcat tcactccacc ctgaatccca
     3601 cctgggacca aaccattata tttgatgacg ttgaaatctt tggggagccc caaacagttc
     3661 tgcagaaccc gcccaaagtc atcatcgaac tttttgacag tgaccaagtg ggcaaagatg
     3721 agtttttagg tcgaagcatt tgctctcctc tggtgaaact gaactcagaa acagacacca
     3781 cacctaagct tctctggcac ccagttatga atggagataa ggcctgtggg gatgtccttg
     3841 taacagcaga actgattctg aggaacaagg acggctccaa ccttcccatc ctcccctctc
     3901 aaagagcacc aaacttatac atggtccctc aagggatcag acctgtggtt cagctcaccg
     3961 ctattgagat cctagcttgg ggcttaagaa atatgaaaaa ctaccagatg gcttccatca
     4021 cctcgcccag cctcgtggtg gagtgcggag gagagagagt agaatcggtg gtgatcaaaa
     4081 gcctcaagaa gacacccaac ttcccaagtt ctgttctctt catgaaagtg ttcttgccca
     4141 aggaagaatt gtacatgcca ccactggtga tcaaggtcat tgatcacagg cagttcgggc
     4201 ggaagcctgt ggtcggccaa tgcaccattg accacctgga ccgctttcgg tgtgatccat
     4261 atgcaggaaa ggaggacatt gtaccgcaac taaaagcttc ccttatgtct gcacccccat
     4321 gccgggatgt cattattgaa atagaagaca ccaaaccatt gctggcttct aagctgtcag
     4381 aaaaggagga agaaatcgtt gactggtgga gtaaatttta tgcttcctcg ggggagcatg
     4441 aaaaatgtgg acagtatatt cagaaaggct attccaaact caagatctat gactgtgaac
     4501 tggaggacgt agctgacttt gaaggcctga cagatttctc agataccttc aagttgtaca
     4561 gaggcaagtc cgatgagaat gaagatccgt ccgtggtagg agagtttaaa ggctccttcc
     4621 gaatctaccc cttgccggat gaccccagtg tgccggcccc tcccaggcag tttcgggaac
     4681 tgcctgacag tgtcccgcag gaatgcacgg ttaggattta cattgttcaa ggcttacagc
     4741 tccagcccca ggacaacaat ggcctgtgtg atccttacat aaaaataacc ctgggcaaaa
     4801 aagtaattga agacagagac cattacattc ccaacactat caacccagtg ttcggcagaa
     4861 tgtatgaact gagctgctac ttacctcaag agaaagacct gaagatctct gtctatgact
     4921 acgacacctt cacccgagat gagaaggtgg gagagacaac cattgacctg gagaaccgct
     4981 tcctgtcccg gttcgggtct cactgcggca tccctgagca gtactgtgtt tctggagtga
     5041 acacctggcg agatcagctg agaccgacac agttgcttca aaacgtagcc agattcaaag
     5101 gcttcccgcc accagtcctt tctgaagatg gaagcaggat ccaatatgga ggaagagact
     5161 atcatctgga tgagtttgag gccaacaaaa tcctgcacca gcaccttgga gcccctgaag
     5221 agcgtcttgc cctccatatt ctcaggactc agggcctggt ccctgagcac gtggagacaa
     5281 ggactttgca cagcaccttc cagcccaata tttcccaggg aaaacttcag atgtgggtgg
     5341 atgtcttccc caagagtcta ggaccaccag gtcccccttt caacatcact cccaggaaag
     5401 ccaagacgta ctatctgcgt gtcatcatct ggaataccag ggacgttatc ttggatgaga
     5461 agagcatcac tggggaggac atgagcgaca tctacgtcaa aggctggatt tccggcagcg
     5521 aagaaaacaa acagaaaaca gatgtccact acaggtcctt ggatggcgaa ggcaatttta
     5581 actggagatt tgttttccca tttgactacc tccccgctga gcagctctgt atcgtcgcta
     5641 aaaaagagca tttctggagt attgatcaaa cagaattccg agtgccccct cggctgatca
     5701 ttcagatatg ggacaatgac aagttttccc tggacgacta cttgggtttt ctggaactcg
     5761 acttgcatcg tacgatcatc ccagccaaga cctcggagaa atgcagtttg gacatgattc
     5821 cagacctcaa agccatggac cctcttaagg ctaagactgc ttctctcttt gaacagaagt
     5881 ccatgaaagg ctggtggcca tgctacgcag acaaagatgg ctcccgcgtg atggctggga
     5941 aagtggagat gacactggag gtcctcaacg agagggaggc cgacgagagg ccagccggga
     6001 aagggcggag tgaacccaac atgaacccca agcttgaccc accaaaccga ccggaaacct
     6061 ccttcctctg gttcacgaac ccttgcaaga ccatgcgctt catcgtgtgg cgccggttca
     6121 agtgggtgat catcggcctg cttctgctgc tcatcctgct gctgttcgtg gctgtgctcc
     6181 tgtactcgct gccgaactat ttatccatga agattgtgag gccaaatgca tgataaaagc
     6241 aaagccttca gtcacccagc gacggagaac tctcgcctca catacgtctg tgtgacgttc
     6301 gagacagtct caggcgactc caccaaggca caccagctcc tagaggggct gaatcccaga
     6361 aagtcagaca gcaggcaaca tttttatcat gttatctctt gaaatattaa aaaagcatta
     6421 ttttctaaac ttgtaagcat atttgcagag tatttctaag gtggctggtt ccattttttt
     6481 tttttaagaa aaatctttta atgtgctctg cattctatga gtcaagtttg ggaagtcggt
     6541 gaaatgactt tgaagtgtct tgtaccttaa tgtcatatat cctatttgta atcaaaagaa
     6601 aagactgcat taaaaaaaga cagggctcat agttagagta gctcttaccg gtgcctgtaa
     6661 ccattgttac ggtattttgt atggacagat gtcatgagac tctttgcaac ttgagtgtaa
     6721 ataaaactat ctcaaacttg tacacaca
//
