LOCUS       NM_001271066            7093 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus myosin IXb (Myo9b), transcript variant 1, mRNA.
ACCESSION   NM_001271066
VERSION     NM_001271066.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 7093)
  AUTHORS   Kong,R., Yi,F., Wen,P., Liu,J., Chen,X., Ren,J., Li,X., Shang,Y.,
            Nie,Y., Wu,K., Fan,D., Zhu,L., Feng,W. and Wu,J.Y.
  TITLE     Myo9b is a key player in SLIT/ROBO-mediated lung tumor suppression
  JOURNAL   J Clin Invest 125 (12), 4407-4420 (2015)
   PUBMED   26529257
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7093)
  AUTHORS   Long,H., Zhu,X., Yang,P., Gao,Q., Chen,Y. and Ma,L.
  TITLE     Myo9b and RICS modulate dendritic morphology of cortical neurons
  JOURNAL   Cereb Cortex 23 (1), 71-79 (2013)
   PUBMED   22250289
  REMARK    GeneRIF: data demonstrate that Myo9b and RICS repress RhoA/Rock
            signaling and modulate dendritic morphogenesis in cortical neurons
REFERENCE   3  (bases 1 to 7093)
  AUTHORS   Hanley,P.J., Xu,Y., Kronlage,M., Grobe,K., Schon,P., Song,J.,
            Sorokin,L., Schwab,A. and Bahler,M.
  TITLE     Motorized RhoGAP myosin IXb (Myo9b) controls cell shape and
            motility
  JOURNAL   Proc Natl Acad Sci U S A 107 (27), 12145-12150 (2010)
   PUBMED   20566876
REFERENCE   4  (bases 1 to 7093)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   5  (bases 1 to 7093)
  AUTHORS   Struchholz,S., Elfrink,K., Pieper,U., Kalhammer,G., Honnert,U.,
            Grutzner,A., Linke,W.A., Liao,W. and Bahler,M.
  TITLE     Functional role of the extended loop 2 in the myosin 9b head for
            binding F-actin
  JOURNAL   J Biol Chem 284 (6), 3663-3671 (2009)
   PUBMED   19059909
  REMARK    GeneRIF: the extended loop 2 in Myo9b binds F-actin and influences
            the binding of the conventional stereo-specific actin-binding site.
REFERENCE   6  (bases 1 to 7093)
  AUTHORS   Inoue,A., Saito,J., Ikebe,R. and Ikebe,M.
  TITLE     Myosin IXb is a single-headed minus-end-directed processive motor
  JOURNAL   Nat Cell Biol 4 (4), 302-306 (2002)
   PUBMED   11901422
REFERENCE   7  (bases 1 to 7093)
  AUTHORS   Post,P.L., Bokoch,G.M. and Mooseker,M.S.
  TITLE     Human myosin-IXb is a mechanochemically active motor and a GAP for
            rho
  JOURNAL   J Cell Sci 111 (Pt 7), 941-950 (1998)
   PUBMED   9490638
REFERENCE   8  (bases 1 to 7093)
  AUTHORS   Muller,R.T., Honnert,U., Reinhard,J. and Bahler,M.
  TITLE     The rat myosin myr 5 is a GTPase-activating protein for Rho in
            vivo: essential role of arginine 1695
  JOURNAL   Mol Biol Cell 8 (10), 2039-2053 (1997)
   PUBMED   9348541
REFERENCE   9  (bases 1 to 7093)
  AUTHORS   Wirth,J.A., Jensen,K.A., Post,P.L., Bement,W.M. and Mooseker,M.S.
  TITLE     Human myosin-IXb, an unconventional myosin with a chimerin-like
            rho/rac GTPase-activating protein domain in its tail
  JOURNAL   J Cell Sci 109 (Pt 3), 653-661 (1996)
   PUBMED   8907710
REFERENCE   10 (bases 1 to 7093)
  AUTHORS   Reinhard,J., Scheel,A.A., Diekmann,D., Hall,A., Ruppert,C. and
            Bahler,M.
  TITLE     A novel type of myosin implicated in signalling by rho family
            GTPases
  JOURNAL   EMBO J 14 (4), 697-704 (1995)
   PUBMED   7882973
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000275.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by
            NM_001271066.3.
            
            On Feb 10, 2021 this sequence version replaced NM_001271066.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments. Note that the sequence AJ888904.1
            is chimeric. Only the Myo9b sequence region was propagated into
            this RefSeq record.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMD00132261, SAMD00132263
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-89                JACYVU010000275.1  1294781-1294869
            90-985              JACYVU010000275.1  1312000-1312895
            986-1080            JACYVU010000275.1  1333424-1333518
            1081-1143           JACYVU010000275.1  1340137-1340199
            1144-1243           JACYVU010000275.1  1341165-1341264
            1244-1344           JACYVU010000275.1  1341527-1341627
            1345-1474           JACYVU010000275.1  1342249-1342378
            1475-1564           JACYVU010000275.1  1344636-1344725
            1565-1681           JACYVU010000275.1  1346604-1346720
            1682-1816           JACYVU010000275.1  1347295-1347429
            1817-1938           JACYVU010000275.1  1349651-1349772
            1939-2080           JACYVU010000275.1  1351929-1352070
            2081-2285           JACYVU010000275.1  1352412-1352616
            2286-2367           JACYVU010000275.1  1353113-1353194
            2368-2457           JACYVU010000275.1  1354214-1354303
            2458-2472           JACYVU010000275.1  1354539-1354553
            2473-2586           JACYVU010000275.1  1356076-1356189
            2587-2626           JACYVU010000275.1  1357916-1357955
            2627-2749           JACYVU010000275.1  1359664-1359786
            2750-2830           JACYVU010000275.1  1360442-1360522
            2831-2941           JACYVU010000275.1  1360932-1361042
            2942-3064           JACYVU010000275.1  1362216-1362338
            3065-3381           JACYVU010000275.1  1363760-1364076
            3382-4215           JACYVU010000275.1  1364471-1365304
            4216-4270           JACYVU010000275.1  1366089-1366143
            4271-4392           JACYVU010000275.1  1366851-1366972
            4393-4520           JACYVU010000275.1  1370244-1370371
            4521-4696           JACYVU010000275.1  1370533-1370708
            4697-4795           JACYVU010000275.1  1372268-1372366
            4796-4969           JACYVU010000275.1  1372486-1372659
            4970-5008           JACYVU010000275.1  1373052-1373090
            5009-5120           JACYVU010000275.1  1373299-1373410
            5121-5194           JACYVU010000275.1  1373827-1373900
            5195-5387           JACYVU010000275.1  1374292-1374484
            5388-5516           JACYVU010000275.1  1374563-1374691
            5517-5622           JACYVU010000275.1  1374872-1374977
            5623-5754           JACYVU010000275.1  1375053-1375184
            5755-5878           JACYVU010000275.1  1376899-1377022
            5879-5926           JACYVU010000275.1  1377360-1377407
            5927-6060           JACYVU010000275.1  1377674-1377807
            6061-6192           JACYVU010000275.1  1378026-1378157
            6193-7093           JACYVU010000275.1  1378547-1379447
FEATURES             Location/Qualifiers
     source          1..7093
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16p14"
     gene            1..7093
                     /gene="Myo9b"
                     /note="myosin IXb"
                     /db_xref="GeneID:25486"
                     /db_xref="RGD:3146"
     exon            1..89
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            90..985
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     CDS             146..6196
                     /gene="Myo9b"
                     /note="isoform 1 is encoded by transcript variant 1;
                     unconventional myosin-9b; Unconventional myosin from rat
                     3; myr 5; unconventional myosin-IXb"
                     /codon_start=1
                     /product="unconventional myosin-IXb isoform 1"
                     /protein_id="NP_001257995.1"
                     /db_xref="GeneID:25486"
                     /db_xref="RGD:3146"
                     /translation="MSAHEAGSSGRRRPATFHLHIYPQLPSAGSQTSCRVTATKDSTT
                     SDVIRDVVASLHLDGSKHYVLVEVKESGGEEWVLDASDSPVHRVLLWPRRAQKEHPRE
                     DGYYFLLQERNADGSIQYLHVQLLAQPTAACRLVERGLLPRPQADFDDLCNLPELNEA
                     NLLQSLKLRFVQQKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQQLGKLEPHVFAL
                     ADVAYYTMLRKHVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGYASGVERTILGAG
                     PVLEAFGNAKTAHNNNSSRFGKFIQVNYLESGIVRGAVVEKYLLEKSRLVSQEKDERN
                     YHVFYYLLLGVSEEERQEFQLKQPQDYFYLNQHNLNIEDGEDLKHDFERLQQAMEMVG
                     FLPATKKQIFSVLSAILYLGNVTYKKRATGRDEGLEVGPPEVLDTLSQLLKVKRETLV
                     EVLTKRKTITVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALLNKKDME
                     EAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFTQHIFKLEQEEYQGEGIS
                     WHNIDYTDNVGCIHLISKKPTGLFYLLDEESNFPHATSHTLLAKFKQQHEDNKYFLGT
                     PVLEPAFIIQHFAGRVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRQLIGMDPVAV
                     FRWAVLRAAIRAMAVLREAGRLRAERAEKAEAGVSSPVTRSHVEELPRGANTPSEKLY
                     RCAGLDFSFERSEELDVNAFEDIMAFYESRKVRERSDLHNQIIKSLKGLPWQGEDPRR
                     LLQSLSRLQKPRTFFLKSKGIKQKQIIPKNLLDSKSLRLIISMTLHDRTTKSLLHLHK
                     KKKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGM
                     LETVRIRRSGYSAKYTFQDFTEQFQVLLPKDVQPCREAIAALLEKLQVDRQNYQIGKT
                     KVFLKETERQALQERLHGEVLRRILLLQSWFRMVLERRHFVQMKHAALTIQACWRSYR
                     VRRTLERTRAAVYLQAAWRGYLQRQAYHHQRHSIIRLQSLCRGHLQRRSFSQMMLEKQ
                     KAEQARETAGAEMSEGEPSPVAAGEQPSEHPVEDPESLGVETETWMNSKSPNGLSPKK
                     EIPSPEMETPAQKTVPAESHEKVPSSREKRESRRQRGLEHVERQNKHIQSCREENSTL
                     REPSRKASLETGESFPEDTKEPREDGLETWTETAAPSCPKQVPIVGDPPRSPSPLQRP
                     ASLDLDSRVSPVLPSSSLESPQDEDKGENSTKVQDKPESPSGSTQIQRYQHPDTERLA
                     TAVEIWRGKKLASAMLSQSLDLSEKPRTAGAALTPTEERRISFSTSDVSKLSPVKTST
                     EVDGDLSAKKPAGHKKKSEDPSAGPDAGLPTGSQGDSKSAFKRLFLHKAKDKKPSLEG
                     VEETEGSGGQAAQEAPARKTLDVPSSQQHRHTTGEKPLKGKKNRNRKVGQITVSEKWR
                     ESVFRKITNANELKFLDEFLLNKVNDLRSQKTPIESLFIEATERFRSNIKTMYSVPNG
                     KIHVGYKDLMENYQIVVSNLAAERGEKDTNLVLNVFQSLLDEFTRSYNKTDFEPVKGK
                     AQKKKRKQERAVQEHNGHVFASYQVNIPQSCEQCLSYIWLMDKALLCSVCKMTCHKKC
                     VHKIQSYCSYTGRRKSELGAEPGHFGVCVDSLTSDKASVPIVLEKLLEHVEMHGLYTE
                     GLYRKSGAANRTRELRQALQTDPATVKLEDFPIHAITGVLKQWLRELPEPLMTFAQYG
                     DFLRAVELPEKQEQLAAIYAVLDHLPEANHTSLERLIFHLVKVALLEDVNRMSPGALA
                     IIFAPCLLRCPDNSDPLTSMKDVLKITTCVEMLIKEQMRKYKVKMEEINHLEAAESIA
                     FRRLSLLRQNAPWPLKLGFSSPYEGVRTKSPRTPVVQDLEELGALPEEAAGGDEDREK
                     EILMERIQSIKEEKEDITYRLPELDPRGSDEENLDSETSASTESLLEERAVRGAAEGH
                     "
     exon            986..1080
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            1081..1143
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            1144..1243
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            1244..1344
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            1345..1474
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            1475..1564
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            1565..1681
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            1682..1816
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            1817..1938
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            1939..2080
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            2081..2285
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            2286..2367
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            2368..2457
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            2458..2472
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            2473..2586
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            2587..2626
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            2627..2749
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            2750..2830
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            2831..2941
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            2942..3064
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            3065..3381
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            3382..4215
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            4216..4270
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            4271..4392
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            4393..4520
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            4521..4696
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            4697..4795
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            4796..4969
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            4970..5008
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            5009..5120
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            5121..5194
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            5195..5387
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            5388..5516
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            5517..5622
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            5623..5754
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            5755..5878
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            5879..5926
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            5927..6060
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            6061..6192
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
     exon            6193..7093
                     /gene="Myo9b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagggcgagg ctggtcgctc cgggcggggg ggccgcgagc agcgggcggg ccggccggag
       61 accggcggcg cgcagcggtc caagtccagt tgcaggaggt gcgcggcccg ccgatgaggc
      121 atgctgaggc caggaggtgg gcaggatgag tgctcacgag gctggcagct caggccgaag
      181 gcggccggcc accttccacc tgcacatcta ccctcagctg cccagtgctg ggagccagac
      241 ctcatgccgt gtaaccgcca ccaaggacag cacaacaagc gatgtcatcc gagacgtggt
      301 ggccagtcta cacctggacg gctcgaagca ctatgtgctg gtggaggtga aggagtcggg
      361 tggggaggag tgggtgctgg atgccagcga ctcgcctgtg caccgagtgc tgctgtggcc
      421 tcggcgagcg cagaaggagc accctcggga ggacggctac tacttcctgc tgcaggagcg
      481 caacgctgac ggcagcattc agtacctgca cgtgcagctg ctggctcagc ccacagccgc
      541 atgtcgcctg gtggagcgag ggctgctgcc aaggcctcaa gcggacttcg acgacctgtg
      601 caacctgccg gagctgaacg aggccaacct gctgcagagc ctgaagctgc gcttcgtgca
      661 gcagaagatc tacacgtacg cgggcagcat cctggtggcc atcaacccct tcaagttcct
      721 gcccatttac aaccccaagt atgtgaagat gtacgagaac cagcagctgg gaaagctgga
      781 gccgcacgtg ttcgctctgg ccgatgtagc ctactacacc atgctgcgca agcacgtgaa
      841 ccagtgcatc gtcatctctg gtgagagcgg gtccggcaag acgcaaagca ccaacttcct
      901 catccactgc ctcacagcgc tcagccagaa gggctacgcc agcggcgtcg agaggaccat
      961 cctgggtgca gggcctgtgc tggaggcttt tgggaacgcc aagacagccc acaacaacaa
     1021 ctccagccgc ttcgggaagt tcatccaagt caactacctg gagagtggca tcgtgagggg
     1081 agctgttgtg gaaaaatacc ttcttgaaaa gtctcgcctg gtttcccagg agaaggatga
     1141 gcggaactac catgtgtttt attatctgct gctgggcgtc agtgaggaag agcgtcagga
     1201 atttcagctg aagcagcctc aagactattt ctacctcaac cagcataact tgaatattga
     1261 agatggagaa gacctcaaac atgactttga aaggcttcag caggccatgg agatggtggg
     1321 cttcctacct gccacgaaga agcagatctt ctctgtcctc tcagccatcc tgtatcttgg
     1381 caatgtcacc tataagaaga gagccacagg ccgggatgaa ggcctggagg tcgggccccc
     1441 ggaggtattg gacacactat cccagctcct gaaggtaaag cgggagaccc tggtggaggt
     1501 cctaaccaag agaaaaacaa tcacggtcaa tgacaaactc atcctgcctt acagcctcag
     1561 tgaggctatc actgcacgag actccatggc taagtctctg tacagcgccc tgtttgactg
     1621 gattgtgctg aggatcaacc acgccctcct caacaagaag gacatggaag aggctgtttc
     1681 ttgcttgtcc attggcgtcc tggacatatt cggatttgag gactttgaac ggaacagctt
     1741 cgagcagttt tgcatcaact acgccaacga gcagttgcag tactacttca cccagcacat
     1801 cttcaagctg gagcaggagg agtaccaggg tgagggtatc tcgtggcaca acattgacta
     1861 caccgacaac gtgggctgta tccacctcat cagcaagaag cccactggcc tcttctacct
     1921 gctggacgag gaaagcaact ttccccatgc cacaagccac actctgctgg ccaaattcaa
     1981 gcagcagcat gaggacaaca agtacttcct gggcacacca gtcctggagc ccgccttcat
     2041 catccagcac ttcgcaggca gagtaaagta ccagatcaag gacttccggg agaagaacat
     2101 ggactacatg cggcctgaca tcgtggcact gctaaggggc agtgacagct cctatgtgcg
     2161 ccaactcatc ggcatggacc cggtagctgt gttccgctgg gctgtattac gggcagccat
     2221 cagggccatg gctgtgctgc gggaggctgg gcgcctgcgt gcagagagag cagagaaagc
     2281 agaagcaggt gtaagtagtc ctgtcactcg aagtcacgtg gaagagctgc caagaggagc
     2341 caacacccct tcagagaaac tgtaccgctg cgcagggcta gacttctcct ttgagcgctc
     2401 tgaggagctg gatgttaacg cttttgagga catcatggct ttctatgaga gcaggaaggt
     2461 gagggagcgg agcgatttgc ataaccaaat catcaagagc ctcaaaggac tgccatggca
     2521 gggcgaggac ccgcggaggc ttctccagtc cctcagtcgg ctccagaagc cccgcacctt
     2581 cttcctgaag agtaaaggta tcaaacaaaa gcagatcatt cccaagaacc tgctggactc
     2641 taagtccctg aggctcatca tcagcatgac gctgcatgac cgaactacca agtcactgct
     2701 gcacctgcac aagaagaaga agccgcccag catcagtgca cagttccaga catctcttaa
     2761 caagctgttg gaggcgctgg gcaaggctga gcccttcttc atccgctgca ttcgctccaa
     2821 tgccgagaag aaggagctct gctttgatga tgagctggtg cttcagcaac tgcgctacac
     2881 aggcatgctg gagaccgtgc gcatccggcg ctctggctac agcgccaagt acaccttcca
     2941 ggacttcacg gagcagttcc aggtgctgct gcccaaggat gtccagccct gtagggaggc
     3001 cattgctgcc ctgttggaga agctgcaggt ggacaggcag aactaccaga tcgggaagac
     3061 gaaggtcttc ctgaaggaga cagagcggca ggccctgcag gagaggctgc atggtgaggt
     3121 cttacgcagg atcctgctgc tgcagagttg gttccggatg gtgctggaac gcaggcactt
     3181 tgtgcagatg aagcatgctg ccctgaccat ccaggcctgc tggcggtctt atcgtgtgcg
     3241 ccgtacactg gagaggacgc gggcagctgt gtatcttcag gctgcctgga gaggctacct
     3301 gcagagacag gcctaccacc accagaggca tagcatcatc cgcctgcaga gcctctgccg
     3361 tggccaccta cagcgcagga gcttcagcca gatgatgtta gagaagcaga aggcagagca
     3421 agccagggag actgcaggag cagagatgtc agagggagag cccagccctg tggccgctgg
     3481 ggagcagccg tctgagcacc ctgtggagga ccctgagagc ctgggtgtgg agactgagac
     3541 ctggatgaac agcaagtccc caaatggctt gtcacctaag aaggagatcc ccagcccgga
     3601 gatggagacc ccagcccaaa aaacagtgcc agctgaaagt catgagaaag tccccagtag
     3661 ccgggagaag cgagagtcac ggcggcagcg agggttggag catgttgaac gacagaacaa
     3721 acacatccaa tcctgcaggg aggagaatag caccctccga gaaccttcca gaaaggcaag
     3781 cctggaaaca ggggagagct tccctgagga cacaaaggag cccagagaag atggacttga
     3841 gacatggact gagaccgcag ccccctcttg tccaaagcag gtgccgattg tgggagatcc
     3901 gcctaggagt cccagtccct tgcagaggcc cgccagcctg gacctagaca gcagggttag
     3961 cccagtgctc cccagcagct ccctggaatc cccccaggat gaggacaagg gtgagaacag
     4021 caccaaggtt caggacaagc ccgagagtcc cagtggctcc acccagatcc aacggtacca
     4081 acacccggac acagagcggc tagccactgc tgtggagata tggcgaggca agaagctcgc
     4141 cagtgccatg ctgagccaat ccctggacct gagtgagaag ccccggactg caggggcagc
     4201 cctgactccc acagaggaga ggcgcatctc cttctccacc agtgatgtct ccaagctgtc
     4261 cccggtcaag acttcaactg aagtcgatgg ggatctgagc gccaagaagc cagccggcca
     4321 taagaagaag tcagaagacc catctgctgg tcccgatgca ggcctgccca caggctccca
     4381 gggtgactct aaatctgcct ttaagcgact cttcctgcac aaagccaagg ataagaagcc
     4441 cagcctggag ggtgtggagg agacagaggg cagtggaggg caggctgcac aggaggcccc
     4501 ggccaggaag actctagatg taccttctag ccagcagcac cgccacacca caggcgagaa
     4561 gcctctaaaa gggaagaaga accgaaatcg taaggtcgga cagatcacag tgtccgagaa
     4621 gtggcgagag tcggtgttcc gtaagatcac taatgccaac gagctcaagt ttctggatga
     4681 gttcctgctc aacaaggtga atgaccttcg ctcacagaag acacccatcg agagcttgtt
     4741 cattgaggcc actgagcgtt tcaggagcaa tatcaagacc atgtattctg tgcctaacgg
     4801 gaagatccat gtaggctaca aggacttgat ggagaactac cagatcgttg tcagtaacct
     4861 ggctgccgag cgtggggaga aggacaccaa cctggtcctc aatgtcttcc agtcactgct
     4921 ggatgaattc actcgcagct acaacaagac tgactttgag ccggtcaagg gcaaagccca
     4981 gaagaagaag aggaagcagg agcgtgctgt ccaggaacac aatggacatg tgtttgccag
     5041 ctaccaagtg aacatcccgc agtcgtgtga gcagtgtctg tcctacatct ggctcatgga
     5101 caaggccctg ctatgcagtg tgtgcaagat gacctgccac aagaaatgtg tgcacaagat
     5161 tcagagctat tgctcctaca ctggacggag gaagagtgag ctgggtgccg aaccaggcca
     5221 cttcggcgtg tgtgtagaca gcctgaccag tgacaaggcc tccgtgccca ttgtgctgga
     5281 gaagcttctg gaacatgtag agatgcatgg cctgtatacc gagggtcttt accgcaagtc
     5341 aggcgctgcc aaccggacac gggaattacg ccaggctctg cagacagacc ctgctacagt
     5401 taagctggag gacttcccca tccacgccat caccggggtc ctgaagcaat ggctgcggga
     5461 gctgcctgag ccactcatga cttttgccca gtatggagac ttcctcaggg ctgttgagct
     5521 tccagagaag caggagcagc tggctgccat ctatgcagtc ctggaccacc tgcctgaagc
     5581 caaccacacc tccctggaga ggctcatctt ccaccttgtc aaagtggccc tgcttgaaga
     5641 tgtgaaccgc atgtctccgg gagctctagc tatcatcttc gcgccctgcc tgcttcgctg
     5701 ccctgacaac tccgaccccc tgaccagcat gaaggacgta ctaaagatta ccacgtgtgt
     5761 ggagatgctc atcaaggaac agatgaggaa atacaaggtg aagatggagg agatcaacca
     5821 cctggaggca gctgagagca ttgcgttccg caggctctcc ctgctgaggc agaatgcccc
     5881 gtggcctctc aaactggggt tttcgtctcc ctatgagggg gtccggacca aaagccccag
     5941 gaccccagtg gtccaagact tggaggagct gggggctctc cccgaggagg cggcaggtgg
     6001 tgacgaggac cgggaaaagg agattctcat ggagaggatt cagtccatca aagaagagaa
     6061 ggaggacatc acatatcgac tgccggagct ggacccacgg ggttctgacg aggagaacct
     6121 tgactcagag acatcagcca gcactgagag cctgctggag gagagggccg tgcggggggc
     6181 cgcagaaggt cactgacctg ccatcgcagg gtacactagg acccctggac caccatgatg
     6241 ccatacttcc tggggccaaa cgcaggtatt cagacccccc tacctactgc ctgccctcca
     6301 gctccagcca agccaatggc tgaggaccat gactggccat ctgcgtgttc taaaatcccc
     6361 gaactggcat cccagctgtg gagccggcct tcactctctg agaaggatct agaatgaaaa
     6421 gttcccagag ggatgctgtg gccagctctg tgtgttgtgg aggctgggga ctgctggcca
     6481 ggaccatcag agccccaacc tgcacagcag ttcccccccc ccccctttgt acttttcagt
     6541 aactgtttct ctttttgtgg tttacataac ttttaagttc ataacagcct taatggagga
     6601 ccaaactttt tgtacgtgtg tctgagcttt gatattaact gtccaccgct gtaacctgga
     6661 catgggcagg actagcctgc aaagtggata tgtgggccac acctggcgac tgcactccac
     6721 agccatggag agcaagcaag caagcgaacg agcggactca caagacacct cttacccttg
     6781 aatacctccc agcagcggtc atctggccag agaaccttcc agagattgtg ggagctgtcc
     6841 acagggtcac agctgaaggc aggacagaat gggaagtccc tgcatcgcag ggatgctcta
     6901 cccactgcct gtgggctgca aggagccagg gatcggagct gtagggacaa gcagtgcatg
     6961 tcccgaattt cctctgcagc ccccgtgtca gcctgggttc ttaagaggct ggctctcttc
     7021 tcaggcccta cccagtcctg gacacaagga agccccaccg gaggtgtgaa ataaaagtgc
     7081 ttgacaagtg ttg
//
