LOCUS       XM_008766423            8061 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus myosin VI (Myo6), transcript variant
            X1, mRNA.
ACCESSION   XM_008766423
VERSION     XM_008766423.2
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051343.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_008766423.3.
            
            On Jan 21, 2021 this sequence version replaced XM_008766423.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8061
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..8061
                     /gene="Myo6"
                     /note="myosin VI; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 1 mRNA, 51 ESTs, 2 long
                     SRA reads, 2 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 12 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:315840"
                     /db_xref="RGD:1560646"
     CDS             243..4127
                     /gene="Myo6"
                     /codon_start=1
                     /product="unconventional myosin-VI isoform X1"
                     /protein_id="XP_008764645.1"
                     /db_xref="GeneID:315840"
                     /db_xref="RGD:1560646"
                     /translation="MEDGKPVWAPHPTDGFQMGNIVDIGPDSLTIEPLNQKGKTFLAL
                     INQVFPAEEDSKKDVEDNCSLMYLNEATLLHNVKVRYSKDRIYTYVANILIAVNPYFD
                     IPKIYSSDTIKSYQGKSLGTMPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTEN
                     TKFVLRYLTESYGTGQDIDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKS
                     SVVGGFVSHYLLEKSRICVQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNR
                     GCTRYFANKETDKQILQNRKSPEYVKAGSLKDPLLDDHGDFIRMCTAMKKIGLDDEEK
                     LDLFRVVAGVLHLGNIDFEEAGSTSGGCNLKNKSAPSLEYCAELLGLDQDDLRVSLTT
                     RVMLTTAGGTKGTVIKVPLKVEQANSARDALAKTVYSHLFDHVVDRVNQCFPFETSSY
                     FIGVLDIAGFEYFEHNSFEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHY
                     VDNQDCIDLIEVKLVGILDILDEENRLPQPSDQHFTSVVHQKHKDHFRLTIPRKSKLA
                     VHRNLRDDEGFIIRHFAGAVCYETTQFVEKNNDALHMSLESLICESRDKFIRALFESS
                     TNNNKDTKQKAGKLSFISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEG
                     AQILSQLQCSGMVSVLDLMQGGFPSRASFHELYNMYKKYMPEKLARLDPRLFCKALFK
                     ALGLNEVDYKFGLTKVFFRPGKFAEFDQIMKSDPDHLAELVKRVNLWLVCSRWKKVQW
                     CSLSVIKLKNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEV
                     VSALKDGKPEVNRQIKDLEISIDALMAKIKSTMMTREQIQKEYDALVKSSEDLLSALQ
                     KKKQQEEEAERLRRIQEEMEKERKRREEDEQRRRKEEEERRMKLEMEVKRKQEEEERK
                     KREDDEKRIQAEVEAQLARQREEESQQQAVLAQECRDRELALRIAQNESELISDEAQG
                     DTALRSSSSCPASSKTNGTRPQMTPEQMAKEMSDILSRGPAVQATKAAAGTKKHDLSK
                     WKYAELRDTINTSCDIELLAACREEFHRRLKVYHAWKSKNKKRNTETEQRAPKSVTDY
                     DFAPFLNNSPQQNPAAQLPARQQEIEMNRQQRFFRIPFIRPADQYKDPQNKKKGWWYA
                     HFDGPWIARQMELHPDKPPILLVAGKDDMEMCELNLEETGLTRKRGAEILPRQFEEIW
                     ERCGGIQYLQSAIESRQARPTYATAMLQNLLK"
ORIGIN      
        1 ctccgtcgca gtgacgtgcg cgcctggctg ggcactccgc tgggctctct ggccggcggg
       61 tggagaccga tccggtatct gtcccagcag gaagcgtatc ccggccgccg tcgtctccgg
      121 tgctcgctct cggccgcggc gtcgcgctcg cccttcgcgc ccgcagtccg gcagcctctc
      181 cacggccgcg acccctcgcg cacctgcctc gctcggggag atagtgggta acctccttca
      241 aaatggaaga tggaaagccc gtttgggcgc cccaccccac agatggattt caaatgggca
      301 atattgtgga tattggccct gacagcctaa caattgaacc tttgaaccaa aaaggcaaga
      361 catttttggc tctcataaac caagtattcc ctgcagaaga ggacagcaaa aaagatgtgg
      421 aagataactg ttcactgatg tacttaaatg aagccacact gctccacaat gtcaaagttc
      481 ggtacagtaa agacagaatc tacacgtatg tggccaacat tctgattgca gtgaatccat
      541 actttgatat acctaagata tattcttcag acacaataaa gtcctatcaa ggaaaatctc
      601 ttgggacaat gccacctcat gtctttgcca ttgctgataa ggcttttcga gacatgaagg
      661 tgctcaagat gagccagtct atcattgtgt ctggagaatc aggagctggc aaaacagaga
      721 atacaaagtt tgttctaaga tacttgacag aatcttatgg aacaggtcaa gatattgatg
      781 atagaatcgt tgaagctaat ccacttttag aagcgtttgg aaatgcaaag actgttcgta
      841 acaataatag cagtcgattt ggaaaatttg tagaaattca tttcaacgag aagagttcgg
      901 ttgttggagg atttgtttcc cattaccttc tagagaagtc taggatttgt gttcaaggca
      961 aagaggagcg gaattaccat attttttaca ggctgtgtgc tggggcttca gaagacatta
     1021 gggagaagct tcacttgagc tccccagata attttcggta tctaaatcgg ggctgcacta
     1081 ggtacttcgc caacaaagaa acggacaaac aaattttaca gaaccgaaaa agtcctgagt
     1141 atgttaaggc aggttccttg aaggatcctc tgttagatga ccatggagat tttatcagga
     1201 tgtgcacagc catgaaaaaa atcggtttgg atgatgaaga aaaacttgat ctatttcgag
     1261 tcgtggctgg tgtcctgcac cttggaaata ttgattttga ggaagccgga agcacttcag
     1321 gtggctgcaa tctgaagaac aaatccgccc cctcactgga gtactgtgct gaattgctgg
     1381 gtttggacca agatgacctt cgagtcagtt taaccactag agtcatgctc accacagcag
     1441 ggggcaccaa aggaactgtt ataaaggtcc ccctgaaggt ggaacaggca aacagtgctc
     1501 gagatgctct ggcgaagacg gtctatagcc atctctttga ccacgtggtg gacagggtga
     1561 atcagtgctt tccttttgaa acatcctctt attttattgg agtcctggat attgctggct
     1621 tcgagtactt tgagcacaac agctttgagc agttttgtat caactattgc aatgagaaac
     1681 ttcaacagtt ttttaatgaa aggatcctaa aggaggaaca agaactgtat cagaaagagg
     1741 gcctgggtgt taatgaagtc cattacgtgg acaatcagga ctgcatagat ttgattgaag
     1801 taaaattagt gggaatcctg gatattctgg atgaagaaaa tcgtcttccc cagccgagtg
     1861 accagcactt tacatccgtg gttcaccaga agcacaaaga ccatttccga ctcactattc
     1921 ccaggaaatc taagctggca gtccacagaa acctcagaga tgacgaaggc tttatcatca
     1981 ggcactttgc aggggctgtg tgctatgaga caacccagtt tgtggagaaa aataatgatg
     2041 cactacatat gtctcttgaa tccttgatat gtgagtccag ggacaagttt atacgggcgt
     2101 tgtttgagtc atccacaaat aacaacaaag atacgaaaca aaaggctgga aaacttagct
     2161 tcatcagcgt gggaaacaag ttcaagacac aattaaattt gcttctggat aaacttcgaa
     2221 gtactggagc cagcttcatc cgctgcatca aacccaactt aaagatgaca agtcaccact
     2281 tcgaaggcgc tcagattctg tctcaacttc agtgttcagg tatggtgtct gtgctggacc
     2341 tcatgcaagg gggtttccct tcaagagcct catttcatga actctataac atgtacaaga
     2401 agtacatgcc agaaaaactc gcacgattgg atccacggct attttgtaag gctcttttta
     2461 aagctttggg attaaatgaa gttgactaca agtttgggct gacaaaagta tttttcagac
     2521 ctggcaagtt tgcagaattt gatcagatta tgaagtctga tcctgatcac ttagcagagt
     2581 tggtgaagag agtcaatttg tggctagtct gtagtcgctg gaagaaagtt cagtggtgtt
     2641 cactgtcagt catcaaactg aaaaacaaaa taaaataccg agctgaagca tgcattaaaa
     2701 tgcagaagac catccggatg tggctttgca aaagaagaca caaaccacgc atcgacggcc
     2761 tggttaaggt gggcacactg aagaagcgac tcgataagtt caatgaagtc gtgagtgcgc
     2821 tgaaagacgg aaagccggag gtgaacagac agatcaaaga tcttgaaatt tctatcgatg
     2881 ctctgatggc caaaattaag tccaccatga tgacgaggga gcagatacag aaagagtatg
     2941 atgcactcgt taaaagctcg gaagatctcc tcagtgcgct gcagaaaaag aagcagcagg
     3001 aggaggaggc ggagaggctg aggcgcatcc aagaggagat ggaaaaggaa aggaagagac
     3061 gcgaagaaga cgaacagcgt cggcggaagg aggaggagga gaggcggatg aaacttgaga
     3121 tggaagtgaa gagaaaacaa gaagaagagg aaaggaagaa gcgggaagat gatgagaagc
     3181 gcatccaggc tgaggtggag gcacagctgg caagacagcg ggaagaggag tcccagcagc
     3241 aggcggtcct ggcacaggag tgcagggaca gggagttggc cctgcgcatc gcccagaacg
     3301 agtcggagct catcagtgat gaggctcagg gtgacacggc actccgaagc tcaagttcct
     3361 gcccagcaag ttctaaaact aatggaacca gaccccaaat gacaccggaa caaatggcca
     3421 aagaaatgtc agacattttg agtagaggtc ctgctgtaca agctaccaag gctgctgctg
     3481 gtaccaagaa acacgatctc agtaaatgga aatacgcaga acttcgcgat acaatcaaca
     3541 cttcctgtga cattgagctc ctggcagctt gcagagaaga atttcacagg agactaaaag
     3601 tgtatcatgc ttggaaatcc aagaacaaga agagaaatac tgaaacagag cagcgtgctc
     3661 ccaagtctgt tactgattat gattttgcac catttttgaa caattcacct cagcagaacc
     3721 ccgcggctca gctccctgcc aggcagcagg agattgagat gaaccgacag cagcgtttct
     3781 tccgcatccc cttcatccgc cccgcggacc agtacaaaga cccacagaac aagaagaagg
     3841 gctggtggta cgcccatttt gacggaccat ggattgcccg gcagatggag ctgcaccctg
     3901 acaagccgcc catccttctt gtagctggca aggacgacat ggagatgtgt gaattgaatc
     3961 tcgaggagac aggtctgact cgaaagcgtg gtgctgagat cttgcccaga cagtttgaag
     4021 agatctggga gcgctgtgga ggcatccagt acctgcagag cgccatcgag agcaggcagg
     4081 cccggcccac ctacgctaca gccatgctgc agaacctgct caagtagacc gaagggttcc
     4141 agcctagccc tgaccctcac aggcagggag gtgaccggaa ggttcgccac tcccttgctc
     4201 ctggtagaaa tgccttatgc aaagtgaaca gattttatta atcatggagt ttgttaattt
     4261 gttcaaggtt aattaaggtt gaggtagtgg attcaggacc taaagaagga aaagccctga
     4321 ttccagcagt gacccccacc cctgctctgt ttggtgtttt ctgcacccag acagacagct
     4381 gatacttctc gctctgcaca ctgaccacct tattgctgag tattctcaag gacaaggctt
     4441 tttttttttt aaattcaaaa catttgactt tttaaagaaa aggatgtcac agtgccttta
     4501 taacggagat aatgaaatct tagcttaatt ttgtgcaaga attaaagtac ttgaattgat
     4561 taaggcacag atgtgtttgg tctaaagaac tctattttgt ctgctttttc aaaagtccat
     4621 ggaaatagat ttccccttct tgcagtgtgc ttagtgccct tgatccccaa attctagaat
     4681 tctggaaaga gccttaatgt atagaatgtc ttatgtggag ggaggtgctg ggcgtttgca
     4741 gctcagacat gggatgcttc tctaccaagc tctgtgttgc tcttggaatc tcctcttcct
     4801 aatccacggt agagtaaagg aaatttggat ttttggaatg actagaggta ttgatataac
     4861 tttgtttcat tttggaaggg atgcagggtt gaggcggtgt tctatgactc tactggactg
     4921 aattccacta ttttttccac ttcatctcaa ctgcagtctc tccgtttgaa ccttgtccat
     4981 gttatttcac gtcacttaag ctggtgtact gcttcggaca gctctcttgc ccctgtccct
     5041 cctctgggta tccagtttgg cctttgagac atggtaatta gagagctgct ttgtaaactt
     5101 tgtaatccag aagcccttgc acttagacat agtttgtttc atgctgcagg aagcctttaa
     5161 aacactccct ttgtgttctg tttagtcctg atcagatgtc agcagctggg gctaatattt
     5221 acaactttaa tattaggaac ttagagacaa aaaatacatc aaggagttat gttgacaccc
     5281 aaaggagtct ttgtatttga gaataaaagt agaaagcaga actattcttc acactcccct
     5341 tggtttttaa ataccctgac ctttgaaatt tcaggatttt tattcctctt agctcagtta
     5401 ggaaaatact tcccagctga tgagattcat gctcagaagc ctcgggcact attgtcagaa
     5461 gcactccttt tgcagtgtca tagtactgaa gtacttactg ttatgacatc gtggaatgat
     5521 tgtttttgtt aagggaatta aatggctctg tctgtactaa tgattgaaaa tgtgaatgag
     5581 gttcttttct ggaggctgtt ttactgctta gatttactct cggttggtct tgtgatgggt
     5641 gacagaggcg cagtcaccga aataaacaac ctgttcctcc tcttccacgc tcacttttga
     5701 ttggtgtctt tatttgtgca ggatactgag taacctttat ttcctagtca aaatgaatgt
     5761 agtccttggg gaaaaaaatc cagtggccta atggattctt agtgacttct cagcttggca
     5821 ctgtttgctg aagcactttt atgtatcttc tagatcttcg aataagcact agatgaaaaa
     5881 ttcatcaaaa agtgggaatt atggtaataa cagatcttaa tattttaaag aatttatagg
     5941 aactaaacga cagcaaagca ttgttgaaag tctttgtggt tttcgactga taattctcag
     6001 tcatctccaa ccatttcctt cctaattgtg tcaccgagtt gtcctacagt gatctgtttc
     6061 agatagtctc ctgagttaat tttgccaagc gggagacctg ccctaattca ggcagccttt
     6121 gagcctcctg catctcacag caaccaggtc cttccgggga gacttcagaa catcatgttc
     6181 tggagcacag cagaaagagt gttccacagg gccttgagcc agcttctcta ccatgttttg
     6241 tgggttcaga tccaccaagg ctatgcaaga atttgaggca tccttatttt aatcagttta
     6301 aaccaatata ttatacaaga agaactaatt tctctaatgt ttatcagctc cagtttcttc
     6361 caccacagtg gttgtacgtt ttaatagaac acaacaacaa catcaacaac aacatcaaca
     6421 acaacatcat caacaacaac atgatggcaa gtgtttctgt gttaattcag ttgagacaca
     6481 gtggtcaaag ccagcagcac agttagatgt gtgttagtag agagataggc tctcagtgag
     6541 tacagggatt tctagaggcc tggtggttcc aaaaacttca gccccttcac tgtcatggag
     6601 accacctgtg cacaggtgtc tgagacgaag caaaataaac gaacactagc atgttaaagg
     6661 tgactaggga gccctgaacc cgactaggga gccttaaagg tgactagcga gggtctcacc
     6721 atggcatata aaaagtccag tgaccccttt ggttttacaa gaaaacctct taaggcaaaa
     6781 ctaggagttg cttgcaagat ttagataata gaaaccacag gcaaaataat aacaatagat
     6841 atttattaca tgtcatcttt attgattttt tttccatgct gggtattgaa cccagggctt
     6901 catacaggtg aggctctacc acggtgacac ctccctggct tttagttggc tatttttgga
     6961 agagagtttc actcacaggt tactaaaatg gttctcaggg gattcacata tgtagatctt
     7021 tgtctttcat ttttcttttc tttttatctt taaaatactt gatttagcag aatagttatt
     7081 gaactaatca gtcaattaat actgttaatg ataatcttac ttctttatat gaaaaaagtt
     7141 gtagcaagcc aggaaggtca tacagtttgc tcccagacca taaaaaagat gtaaatgcct
     7201 ttgctttagc cacggaggga aaacaatgtt tgtccgctta gcagatccct ggagacttac
     7261 aaagggttgt tcctggactt ttctgtttgt ccttaacacc ggtaaataaa tattgagttt
     7321 taattggttc cagaagatgc agtagcagtg gagggggaga gggcagagga catttcacag
     7381 tgaggagaag gatgaggtgt gggaagagtg ataagcatag ggcagagcag agccttagtg
     7441 gaagaaggga gatgctgcag cctccgaaga ctgcattcag tggggatgca ggcactcaga
     7501 caccctagac agccaacact ctcaggtcct ggctgagttt tgggatgtat ttgctacagc
     7561 ttaggggcag aaattaaggt tagtaaagtt gggtcgtgag tcacctggca tgtagacctt
     7621 agcaggtaag aatggtgcag ctgaactgga ggcacccagg aaagaccttg gcatctttga
     7681 tacgagccat gtgcaagggc cagtggagag tctgcctgtg tcagtgctgc accttttgat
     7741 aatttggtcc aattcaaatc agcgtcttct ttcccctctg tatgatgtaa ttttgattct
     7801 tggaagtatt ccaggagata attaggaaaa attaatgcac attgaaaact gcacaatctt
     7861 taatcttaat tttcatcgaa atggaaactc aacgtcaaat tacaaacaga cttattaaac
     7921 agccaccgtt cttctcactt ctggaagttt gtctatttgt aattgctaat ttttattcat
     7981 ttcctcaaaa gtgtgtgtct aatactttcc taaaatactg atgtactgga aactcaaata
     8041 aattgccgta tgtgtagaac a
//
