LOCUS       NM_001134843            3292 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus myosin IG (Myo1g), mRNA.
ACCESSION   NM_001134843 XM_573653
VERSION     NM_001134843.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3292)
  AUTHORS   Gerard,A., Patino-Lopez,G., Beemiller,P., Nambiar,R., Ben-Aissa,K.,
            Liu,Y., Totah,F.J., Tyska,M.J., Shaw,S. and Krummel,M.F.
  TITLE     Detection of rare antigen-presenting cells through T cell-intrinsic
            meandering motility, mediated by Myo1g
  JOURNAL   Cell 158 (3), 492-505 (2014)
   PUBMED   25083865
REFERENCE   2  (bases 1 to 3292)
  AUTHORS   Maravillas-Montero,J.L., Lopez-Ortega,O., Patino-Lopez,G. and
            Santos-Argumedo,L.
  TITLE     Myosin 1g regulates cytoskeleton plasticity, cell migration,
            exocytosis, and endocytosis in B lymphocytes
  JOURNAL   Eur J Immunol 44 (3), 877-886 (2014)
   PUBMED   24310084
REFERENCE   3  (bases 1 to 3292)
  AUTHORS   Dart,A.E., Tollis,S., Bright,M.D., Frankel,G. and Endres,R.G.
  TITLE     The motor protein myosin 1G functions in FcgammaR-mediated
            phagocytosis
  JOURNAL   J Cell Sci 125 (Pt 24), 6020-6029 (2012)
   PUBMED   23038771
REFERENCE   4  (bases 1 to 3292)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   5  (bases 1 to 3292)
  AUTHORS   Olety,B., Walte,M., Honnert,U., Schillers,H. and Bahler,M.
  TITLE     Myosin 1G (Myo1G) is a haematopoietic specific myosin that
            localises to the plasma membrane and regulates cell elasticity
  JOURNAL   FEBS Lett 584 (3), 493-499 (2010)
   PUBMED   19968988
REFERENCE   6  (bases 1 to 3292)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000014.1.
            
            On Sep 9, 2008 this sequence version replaced XM_573653.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA5760383, SAMEA5760386
                              [ECO:0000350]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-215               JAXUCZ010000014.1  85615546-85615760   c
            216-424             JAXUCZ010000014.1  85613855-85614063   c
            425-518             JAXUCZ010000014.1  85613610-85613703   c
            519-684             JAXUCZ010000014.1  85612708-85612873   c
            685-738             JAXUCZ010000014.1  85612431-85612484   c
            739-840             JAXUCZ010000014.1  85611938-85612039   c
            841-957             JAXUCZ010000014.1  85611594-85611710   c
            958-1182            JAXUCZ010000014.1  85610938-85611162   c
            1183-1328           JAXUCZ010000014.1  85610705-85610850   c
            1329-1443           JAXUCZ010000014.1  85609843-85609957   c
            1444-1614           JAXUCZ010000014.1  85609506-85609676   c
            1615-1685           JAXUCZ010000014.1  85609216-85609286   c
            1686-1760           JAXUCZ010000014.1  85606795-85606869   c
            1761-1893           JAXUCZ010000014.1  85606346-85606478   c
            1894-2060           JAXUCZ010000014.1  85605675-85605841   c
            2061-2268           JAXUCZ010000014.1  85605085-85605292   c
            2269-2492           JAXUCZ010000014.1  85604236-85604459   c
            2493-2637           JAXUCZ010000014.1  85603593-85603737   c
            2638-2742           JAXUCZ010000014.1  85602289-85602393   c
            2743-2856           JAXUCZ010000014.1  85601962-85602075   c
            2857-3011           JAXUCZ010000014.1  85600973-85601127   c
            3012-3292           JAXUCZ010000014.1  85600619-85600899   c
FEATURES             Location/Qualifiers
     source          1..3292
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14q21"
     gene            1..3292
                     /gene="Myo1g"
                     /note="myosin IG"
                     /db_xref="GeneID:289785"
                     /db_xref="RGD:1306016"
     exon            1..215
                     /gene="Myo1g"
                     /inference="alignment:Splign:2.1.0"
     CDS             121..3168
                     /gene="Myo1g"
                     /note="myosin-Ig"
                     /codon_start=1
                     /product="unconventional myosin-Ig"
                     /protein_id="NP_001128315.1"
                     /db_xref="GeneID:289785"
                     /db_xref="RGD:1306016"
                     /translation="MEDEEGPEYGKPDFVLLDQLTMEEFMKNLQLRFEKGRIYTYIGE
                     VLVSVNPYQELPLYGPEAIAKYQGRELYERPPHLYAVANAAYKAMKRRSRDTCIVISG
                     ESGAGKTEASKHIMQYIAAVTNPSQRAEVERVKDVLLKSTCVLEAFGNARTNRNHNSS
                     RFGKYMDINFDFKGDPVGGHIHSYLLEKSRVLKQHVGERNFHAFYQLLRGSEDQELQE
                     LHLERNPAVYNFTRQGAGLNMGALGSDEKSHQGVMEAMKIIGFSPEEVESIHRILAAI
                     LHLGNIEFVETEENGPQKGGLEVADEALVGYVAKLTATPSDLVLRTLLARTVASGGRE
                     VIEKSHTVAEASYARDACAKAMYQRLFEWVVNKINSIMEPRDRDPRRDGKDTVIGVLD
                     IYGFEVFPVNSFEQFCINYCNEKLQQLFIQLILKQEQEEYEREGITWQSIEYFNNATI
                     VELVEQPRRGILAVLDEACSTAGPITDRIFLQTLDTHHRHHPHYSSRQLCPTDKTMEF
                     GRDFQIKHYAGDVTYSVEGFIDKNRDSLFQDFKRLLYNSMDPTLRAMWPDGQQDITEV
                     TKRPLTAGTLFKNSMIALVENLASKEPFYVRCIKPNEDKVPGRLDEAHCRHQVEYLGL
                     LENVRVRRAGFASRQPYPRFLLRYKMTCEYTWPNHLLGSDREAVSALLEQHGLQGDVA
                     FGHSKLFIRSPRTLVTLEQSRAHLIPIIVLLLQKAWRGTLARWRCRRLRAIYTIMGWF
                     RRHKVRAHLIELQRRFQAARQPPLYGRDLVWPTPPAVLQPFQDTCHILFSRWRARQLV
                     KNIPPSDMTQIKAKVAAMGALQGLRQDWGCQRAWARDYLSSDTDNPTASHLFAEQLKA
                     LREKDGFGTVLFSSHVRKVNRFRKRRDRALLLTDRHLYKLEPGRQYRVMRAVPLDAVT
                     GLSVTSGRDQLVVLHAQGHDDLVVCLHRSQPPLDNRIGELVGMLVSHCQGEGRTLEIR
                     VSDCIPLSQRGARRLISVEPRPEQTEPDFQCSRSTFTLLWPSH"
     exon            216..424
                     /gene="Myo1g"
                     /inference="alignment:Splign:2.1.0"
     exon            425..518
                     /gene="Myo1g"
                     /inference="alignment:Splign:2.1.0"
     exon            519..684
                     /gene="Myo1g"
                     /inference="alignment:Splign:2.1.0"
     exon            685..738
                     /gene="Myo1g"
                     /inference="alignment:Splign:2.1.0"
     exon            739..840
                     /gene="Myo1g"
                     /inference="alignment:Splign:2.1.0"
     exon            841..957
                     /gene="Myo1g"
                     /inference="alignment:Splign:2.1.0"
     exon            958..1182
                     /gene="Myo1g"
                     /inference="alignment:Splign:2.1.0"
     exon            1183..1328
                     /gene="Myo1g"
                     /inference="alignment:Splign:2.1.0"
     exon            1329..1443
                     /gene="Myo1g"
                     /inference="alignment:Splign:2.1.0"
     exon            1444..1614
                     /gene="Myo1g"
                     /inference="alignment:Splign:2.1.0"
     exon            1615..1685
                     /gene="Myo1g"
                     /inference="alignment:Splign:2.1.0"
     exon            1686..1760
                     /gene="Myo1g"
                     /inference="alignment:Splign:2.1.0"
     exon            1761..1893
                     /gene="Myo1g"
                     /inference="alignment:Splign:2.1.0"
     exon            1894..2060
                     /gene="Myo1g"
                     /inference="alignment:Splign:2.1.0"
     exon            2061..2268
                     /gene="Myo1g"
                     /inference="alignment:Splign:2.1.0"
     exon            2269..2492
                     /gene="Myo1g"
                     /inference="alignment:Splign:2.1.0"
     exon            2493..2637
                     /gene="Myo1g"
                     /inference="alignment:Splign:2.1.0"
     exon            2638..2742
                     /gene="Myo1g"
                     /inference="alignment:Splign:2.1.0"
     exon            2743..2856
                     /gene="Myo1g"
                     /inference="alignment:Splign:2.1.0"
     exon            2857..3011
                     /gene="Myo1g"
                     /inference="alignment:Splign:2.1.0"
     exon            3012..3292
                     /gene="Myo1g"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttcctacttt actacagttc tgcaggagtt aggcagtgct gggcctcccc tttctgtctt
       61 ccccttgacc tctgtacaga aagctctggc gtcctggtct ggaggcttcc agtgggcagg
      121 atggaggatg aagaaggtcc tgagtatggg aaaccagact ttgtgctttt ggaccaacta
      181 acaatggagg agtttatgaa gaacctacag ctcaggtttg agaagggccg tatctatacc
      241 tacattggcg aggtgctggt atctgtgaac ccctaccagg aactgccatt gtatgggcca
      301 gaggccattg ccaagtacca gggccgtgag ctctatgagc gaccacctca tctttacgcc
      361 gtggccaatg ctgcttacaa ggcaatgaag cgcagatcca gggacacctg cattgtcatc
      421 tcaggggaga gtggagcagg gaagacggaa gccagcaagc acatcatgca gtacattgct
      481 gctgtcacca acccaagcca gagggctgag gtagagaggg tgaaggacgt tcttctcaag
      541 tctacctgtg tgctggaagc ctttggcaat gcccgcacca accgcaacca caactccagc
      601 cgctttggca agtacatgga catcaacttc gacttcaagg gggatcctgt tggaggacac
      661 atccacagct acctgctaga gaagtctagg gttctcaagc agcatgtggg ggagaggaac
      721 ttccatgctt tctaccagtt gcttcggggc agcgaggacc aagagctgca agagctgcat
      781 ctggagagaa atcccgctgt gtataatttc acgcgtcagg gagctgggct caacatgggt
      841 gccttgggta gtgatgagaa gagccaccaa ggagtgatgg aggccatgaa gattatcggc
      901 ttcagtcccg aggaggtaga atccatccat cgtatcctag ccgccatatt gcacctggga
      961 aacatcgaat ttgtggagac agaggaaaat ggaccacaga aaggaggcct ggaagtggca
     1021 gacgaggccc tggtaggata tgtggccaag ctgacagcca cccccagcga cctcgttctg
     1081 cgaaccctgc tggctcgtac agtggcttca gggggccgag aggtcattga gaagagccac
     1141 actgtggctg aggccagcta tgcccgggac gcctgtgcaa aggcaatgta ccagcgactg
     1201 tttgagtggg ttgtgaacaa gatcaacagc atcatggaac cccgggaccg ggaccctcgg
     1261 cgtgatggca aggacactgt cattggggtg ctggacatct acggctttga agtattccct
     1321 gtcaacagct ttgagcagtt ctgtatcaac tactgcaatg agaagctcca gcagctcttt
     1381 atccagctga ttctgaagca agagcaggag gagtatgagc gagaaggcat cacctggcag
     1441 agcatcgagt acttcaacaa cgccaccatt gtggaacttg tagagcagcc ccgccgaggc
     1501 atcctggctg tactagatga agcctgcagc acggcaggcc ccatcactga ccggatcttc
     1561 ctgcagaccc tggacacaca ccaccgccac cacccacact attccagccg ccagctttgc
     1621 cctacggaca agaccatgga gtttggccga gacttccaga tcaaacacta tgcaggggat
     1681 gtcacgtact ctgtggaagg cttcattgac aagaatagag actctctctt ccaggacttc
     1741 aaacggctgc tgtacaatag catggatccc accttgcgag ccatgtggcc agacgggcaa
     1801 caggacatca cagaagtgac caagcgcccc ctgacagccg gcacactctt taagaattcc
     1861 atgattgccc tggtggagaa cttggcctcc aaggagccct tctatgtccg ctgcataaaa
     1921 cccaacgaag acaaggtacc cggacgactc gatgaagccc actgtcgtca ccaggtcgag
     1981 tacctgggat tactggagaa tgtgagggtc cgcagggctg gctttgcttc ccggcagccc
     2041 taccctcggt tcctgctcag gtacaagatg acctgtgagt acacatggcc caaccacctg
     2101 ctgggctctg acagggaggc ggtgagcgcc cttctggagc agcatgggct acaaggggat
     2161 gtggcctttg gtcacagcaa gctgttcatc cgatccccaa ggacgctggt cactctggag
     2221 cagagccgag ctcacctgat tcctatcatt gtgttactgc tgcagaaggc ttggcggggc
     2281 accctggcca ggtggcgctg caggcgactg agggccatct acaccatcat gggctggttc
     2341 cggaggcaca aagtacgcgc tcacctgatt gaactacagc gacggttcca ggctgcacgg
     2401 cagcccccac tctatggccg tgaccttgtg tggccaacac cacccgctgt gctgcagccg
     2461 ttccaggata cttgccatat tctcttcagc aggtggcggg cacggcagtt agtgaagaac
     2521 atccctcctt cagacatgac ccagatcaag gccaaggtgg ctgctatggg ggccttgcaa
     2581 ggattgaggc aggactgggg ctgccagagg gcctgggccc gagactacct gtcctctgac
     2641 actgacaacc ccacagcttc ccatctgttc gctgagcagc taaaggcact tcgggagaag
     2701 gatggcttcg gaaccgtgct tttctccagc cacgtgcgca aggtgaatcg attccgcaag
     2761 cgccgggacc gggcccttct gctcacagac cggcatctct acaagctgga acctggacga
     2821 cagtaccggg tgatgcgggc tgtgcctctg gatgcggtga cagggctgag tgtgaccagt
     2881 ggacgggacc agctggtggt gctacacgcc caaggccatg atgatcttgt agtgtgtcta
     2941 caccgttccc agccacccct agacaatcga attggggagc tggtgggcat gctggtttca
     3001 cactgccagg gggagggacg aaccctggag atccgtgtct ctgactgtat cccactgagc
     3061 cagcgtggtg cccggcgcct catttccgta gagcccaggc cagagcagac tgagccagat
     3121 ttccaatgca gccgcagtac ctttaccctc ctctggccaa gccactgagc aagctcaagc
     3181 cagcctagcc tggtctccgc acagttctag acacctggtc ttgaccgtac taaaggctag
     3241 gatttgtcca cctttatata gaatgccaca aaataaagat gctatatttg ta
//
