LOCUS       NM_012983               5303 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus myosin ID (Myo1d), mRNA.
ACCESSION   NM_012983 XM_346403
VERSION     NM_012983.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5303)
  AUTHORS   Yamazaki,R., Ishibashi,T., Baba,H. and Yamaguchi,Y.
  TITLE     Unconventional myosin ID is expressed in myelinating
            oligodendrocytes
  JOURNAL   J Neurosci Res 92 (10), 1286-1294 (2014)
   PUBMED   24903835
  REMARK    GeneRIF: This study demonistrated that myosin ID is expressed in
            myelinating oligodendrocytes in rat nerve system.
REFERENCE   2  (bases 1 to 5303)
  AUTHORS   Benesh,A.E., Fleming,J.T., Chiang,C., Carter,B.D. and Tyska,M.J.
  TITLE     Expression and localization of myosin-1d in the developing nervous
            system
  JOURNAL   Brain Res 1440, 9-22 (2012)
   PUBMED   22284616
REFERENCE   3  (bases 1 to 5303)
  AUTHORS   Revenu,C., Ubelmann,F., Hurbain,I., El-Marjou,F., Dingli,F.,
            Loew,D., Delacour,D., Gilet,J., Brot-Laroche,E., Rivero,F.,
            Louvard,D. and Robine,S.
  TITLE     A new role for the architecture of microvillar actin bundles in
            apical retention of membrane proteins
  JOURNAL   Mol Biol Cell 23 (2), 324-336 (2012)
   PUBMED   22114352
REFERENCE   4  (bases 1 to 5303)
  AUTHORS   McConnell,R.E., Benesh,A.E., Mao,S., Tabb,D.L. and Tyska,M.J.
  TITLE     Proteomic analysis of the enterocyte brush border
  JOURNAL   Am J Physiol Gastrointest Liver Physiol 300 (5), G914-G926 (2011)
   PUBMED   21330445
REFERENCE   5  (bases 1 to 5303)
  AUTHORS   Benesh,A.E., Nambiar,R., McConnell,R.E., Mao,S., Tabb,D.L. and
            Tyska,M.J.
  TITLE     Differential localization and dynamics of class I myosins in the
            enterocyte microvillus
  JOURNAL   Mol Biol Cell 21 (6), 970-978 (2010)
   PUBMED   20089841
REFERENCE   6  (bases 1 to 5303)
  AUTHORS   Batters,C., Arthur,C.P., Lin,A., Porter,J., Geeves,M.A.,
            Milligan,R.A., Molloy,J.E. and Coluccio,L.M.
  TITLE     Myo1c is designed for the adaptation response in the inner ear
  JOURNAL   EMBO J 23 (7), 1433-1440 (2004)
   PUBMED   15014434
  REMARK    GeneRIF: Results support a model in which Myo1c possesses a
            strain-sensing ADP-release mechanism, which allows it to adapt to
            mechanical load.
REFERENCE   7  (bases 1 to 5303)
  AUTHORS   Kohler,D., Ruff,C., Meyhofer,E. and Bahler,M.
  TITLE     Different degrees of lever arm rotation control myosin step size
  JOURNAL   J Cell Biol 161 (2), 237-241 (2003)
   PUBMED   12719468
REFERENCE   8  (bases 1 to 5303)
  AUTHORS   Dumont,R.A., Zhao,Y.D., Holt,J.R., Bahler,M. and Gillespie,P.G.
  TITLE     Myosin-I isozymes in neonatal rodent auditory and vestibular
            epithelia
  JOURNAL   J Assoc Res Otolaryngol 3 (4), 375-389 (2002)
   PUBMED   12486594
  REMARK    GeneRIF: At apical surfaces of supporting cells surrounding hair
            cells in auditory epithelia of postnatal rats. In vestibular
            epithelia, in a ring within apical pole of hair cell. Prominent
            only immediately after birth.
REFERENCE   9  (bases 1 to 5303)
  AUTHORS   Huber,L.A., Fialka,I., Paiha,K., Hunziker,W., Sacks,D.B.,
            Bahler,M., Way,M., Gagescu,R. and Gruenberg,J.
  TITLE     Both calmodulin and the unconventional myosin Myr4 regulate
            membrane trafficking along the recycling pathway of MDCK cells
  JOURNAL   Traffic 1 (6), 494-503 (2000)
   PUBMED   11208135
REFERENCE   10 (bases 1 to 5303)
  AUTHORS   Bahler,M., Kroschewski,R., Stoffler,H.E. and Behrmann,T.
  TITLE     Rat myr 4 defines a novel subclass of myosin I: identification,
            distribution, localization, and mapping of calmodulin-binding sites
            with differential calcium sensitivity
  JOURNAL   J Cell Biol 126 (2), 375-389 (1994)
   PUBMED   8034741
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC087027.1.
            
            On Dec 26, 2004 this sequence version replaced NM_012983.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC087027.1, X71997.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..5303
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q26"
     gene            1..5303
                     /gene="Myo1d"
                     /gene_synonym="Myo1c; Myr2; Myr4"
                     /note="myosin ID"
                     /db_xref="GeneID:25485"
                     /db_xref="RGD:621321"
     exon            1..250
                     /gene="Myo1d"
                     /gene_synonym="Myo1c; Myr2; Myr4"
                     /inference="alignment:Splign:2.1.0"
     CDS             156..3176
                     /gene="Myo1d"
                     /gene_synonym="Myo1c; Myr2; Myr4"
                     /note="myosin1C; myosin-Id; myosin heavy chain myr 4;
                     myosin 1C; Unconventional myosin from rat 4 for myosin I
                     heavy chain; myosin IC"
                     /codon_start=1
                     /product="unconventional myosin-Id"
                     /protein_id="NP_037115.2"
                     /db_xref="GeneID:25485"
                     /db_xref="RGD:621321"
                     /translation="MAEQESLEFGKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGE
                     VVVSVNPYKVLNIYGRDTIEQYKGRELYERPPHLFAIADAAYKAMKRRSKDTCIMISG
                     ESGAGKTEASKYIMQYIAAITNPSQRAEIERVKNMLLKSNCVLEAFGNAKTNRNDNSS
                     RFGKYMDINFDFKGDPIGGHINNYLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLHS
                     LHLQKSLSSYNYIRVGAQLKSSINDAAEFKVVADAMKVIGFKPEEIQTVYKILAAILH
                     LGNLKFIVDGDTPLIENGKVVSVIAELLSTKADMVEKALLYRTVATGRDIIDKQHTEQ
                     EASYGRDAFAKAIYERLFCWIVTRINDIIEVKNYDTTVHGKNTVIGVLDIYGFEIFDN
                     NSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQREGIPWKHIDYFNNQIIVDLVEQQHK
                     GIIAILDDACMNVGKVTDGMFLEALNSKLGKHGHFSSRKTCASDKILEFDRDFRIRHY
                     AGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLKNMWPEGKLSITEVTKRPLTAAT
                     LFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRA
                     GFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVKKLIERCGFQDDVAYGKTKIFIR
                     TPRTLFTLEELRAQMLVRVVLFLQKVWRGTLARMRYKRTKAALTIIRYYRRYKVKSYI
                     HEVARRFHGVKNMRDYGKHVKWPTPPKVLRRFEEALQSIFNRWRASQLIKTIPASDLP
                     QVRAKVAAMEMLKGQRADLGLQRAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMN
                     VLFSCHVRKVNRFSKVEDRAIFVTDRHLYKMDPTKQYKVMKTIPLYNLTGLSVSNGKD
                     QLVVFHTKDNKDLIVCLFSKQPTHESRIGELVGVLVNHFKSEKRHLQVNVTNPVQCSL
                     HGKKCTVSVETRLNQPQPDFTKNRSGFILSVPGN"
     exon            251..459
                     /gene="Myo1d"
                     /gene_synonym="Myo1c; Myr2; Myr4"
                     /inference="alignment:Splign:2.1.0"
     exon            460..553
                     /gene="Myo1d"
                     /gene_synonym="Myo1c; Myr2; Myr4"
                     /inference="alignment:Splign:2.1.0"
     exon            554..719
                     /gene="Myo1d"
                     /gene_synonym="Myo1c; Myr2; Myr4"
                     /inference="alignment:Splign:2.1.0"
     exon            720..773
                     /gene="Myo1d"
                     /gene_synonym="Myo1c; Myr2; Myr4"
                     /inference="alignment:Splign:2.1.0"
     exon            774..869
                     /gene="Myo1d"
                     /gene_synonym="Myo1c; Myr2; Myr4"
                     /inference="alignment:Splign:2.1.0"
     exon            870..986
                     /gene="Myo1d"
                     /gene_synonym="Myo1c; Myr2; Myr4"
                     /inference="alignment:Splign:2.1.0"
     exon            987..1190
                     /gene="Myo1d"
                     /gene_synonym="Myo1c; Myr2; Myr4"
                     /inference="alignment:Splign:2.1.0"
     exon            1191..1336
                     /gene="Myo1d"
                     /gene_synonym="Myo1c; Myr2; Myr4"
                     /inference="alignment:Splign:2.1.0"
     exon            1337..1451
                     /gene="Myo1d"
                     /gene_synonym="Myo1c; Myr2; Myr4"
                     /inference="alignment:Splign:2.1.0"
     exon            1452..1622
                     /gene="Myo1d"
                     /gene_synonym="Myo1c; Myr2; Myr4"
                     /inference="alignment:Splign:2.1.0"
     exon            1623..1693
                     /gene="Myo1d"
                     /gene_synonym="Myo1c; Myr2; Myr4"
                     /inference="alignment:Splign:2.1.0"
     exon            1694..1768
                     /gene="Myo1d"
                     /gene_synonym="Myo1c; Myr2; Myr4"
                     /inference="alignment:Splign:2.1.0"
     exon            1769..1901
                     /gene="Myo1d"
                     /gene_synonym="Myo1c; Myr2; Myr4"
                     /inference="alignment:Splign:2.1.0"
     exon            1902..2068
                     /gene="Myo1d"
                     /gene_synonym="Myo1c; Myr2; Myr4"
                     /inference="alignment:Splign:2.1.0"
     exon            2069..2276
                     /gene="Myo1d"
                     /gene_synonym="Myo1c; Myr2; Myr4"
                     /inference="alignment:Splign:2.1.0"
     exon            2277..2500
                     /gene="Myo1d"
                     /gene_synonym="Myo1c; Myr2; Myr4"
                     /inference="alignment:Splign:2.1.0"
     exon            2501..2645
                     /gene="Myo1d"
                     /gene_synonym="Myo1c; Myr2; Myr4"
                     /inference="alignment:Splign:2.1.0"
     exon            2646..2750
                     /gene="Myo1d"
                     /gene_synonym="Myo1c; Myr2; Myr4"
                     /inference="alignment:Splign:2.1.0"
     exon            2751..2864
                     /gene="Myo1d"
                     /gene_synonym="Myo1c; Myr2; Myr4"
                     /inference="alignment:Splign:2.1.0"
     exon            2865..3019
                     /gene="Myo1d"
                     /gene_synonym="Myo1c; Myr2; Myr4"
                     /inference="alignment:Splign:2.1.0"
     exon            3020..5278
                     /gene="Myo1d"
                     /gene_synonym="Myo1c; Myr2; Myr4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cacccctcag ccaccgcggg aggagcggaa gccgccggcc tcgcccgttc agagctacgc
       61 gggccggagc tctgaggagt ggcggccgtc tatctccggc ccgaccccgt ccgagcaccc
      121 ccgccccagc ccgagtgccc acctgagccg gcgccatggc ggagcaggag agccttgagt
      181 ttggcaaggc ggacttcgtg ctgatggaca ccgtctccat gcccgagttc atggccaacc
      241 ttaggctcag atttgagaaa ggacgcatct atacattcat tggcgaggtg gtcgtttccg
      301 tgaacccata caaggtgctg aacatctatg gaagggacac aattgagcag tacaaaggtc
      361 gggagctgta cgagagacct cctcatctct tcgctattgc tgacgctgct tacaaggcta
      421 tgaagaggcg atcaaaagac acctgtatta tgatatcagg ggaaagtgga gctggtaaaa
      481 cagaggccag taagtacatc atgcagtata tcgccgccat caccaacccc agccagagag
      541 cagagataga aagagtgaag aatatgttgc tgaagtcaaa ctgtgttttg gaagcttttg
      601 gaaatgccaa aaccaatcgc aatgacaatt ccagcaggtt tgggaaatac atggatatca
      661 actttgactt caagggagac cccattgggg gacatattaa taactacttg ctggaaaagt
      721 ctcgtgtaat tgtgcaacag cccggagaac gaagcttcca ttctttctat cagctacttc
      781 agggaggttc cgagcagatg ctgcattctc tacatctgca gaaatcactc tcatcctaca
      841 actacatccg tgtgggggca caactgaagt cttccatcaa tgatgctgca gagttcaaag
      901 ttgtagctga tgccatgaaa gtaattggat tcaaacctga ggagattcaa acagtgtata
      961 aaattctggc tgctattctt cacttgggaa atttaaaatt tatagtagat ggtgacacgc
     1021 cacttattga gaatggcaaa gttgtatctg tcatagcaga attgctctca accaaggcag
     1081 acatggtgga gaaagccctg ctttaccgga cggtggccac aggccgtgac atcattgaca
     1141 aacagcacac ggaacaggag gctagctacg gcagagacgc ctttgccaag gcaatatatg
     1201 agcgcctctt ttgttggatt gttactcgca tcaatgacat catcgaggtc aagaactacg
     1261 acaccacagt acatgggaaa aacacagtta ttggcgtctt ggatatctat ggctttgaaa
     1321 tctttgacaa caacagcttc gagcagttct gcattaacta ctgcaatgag aagctgcagc
     1381 agctgttcat tcagctggtg ctgaagcagg agcaagagga gtaccagcgg gaaggaatcc
     1441 cctggaaaca cattgattac ttcaacaacc agatcattgt ggacctcgtg gagcagcagc
     1501 acaaaggcat cattgcaatc ctggatgacg cgtgtatgaa tgttggcaaa gtcactgatg
     1561 gaatgttcct cgaggccctt aacagtaaat tgggcaaaca tggtcatttt tccagccgaa
     1621 agacctgtgc ctcagacaaa atcctggagt ttgatcggga ctttcgaatc cggcattatg
     1681 caggtgatgt cgtgtattct gtcatcggtt tcattgacaa aaacaaagat actttatttc
     1741 aagacttcaa gcgcctcatg tataacagct caaatcctgt gctgaagaac atgtggccgg
     1801 aaggcaaact gagcattaca gaggtgacca agaggcctct gaccgccgcc accctgttta
     1861 agaattccat gattgcttta gtagacaacc ttgcttcaaa ggagccatac tatgtacgtt
     1921 gcatcaaacc caacgacaag aagtccccac agatttttga tgatgagcgc tgccgccatc
     1981 aggtagaata cctgggactc ctggaaaatg tgagagtgcg ccgggcaggg tttgccttcc
     2041 gccagaccta tgagaagttt cttcacagat acaagatgat ctctgagttc acctggccta
     2101 accacgacct tccttcagac aaggaggctg tcaagaaact catagagcga tgtggctttc
     2161 aggatgacgt agcatatggg aagaccaaaa ttttcattcg aacaccccgt acgctgttca
     2221 ctttggaaga actccgcgcc cagatgctcg tcagggttgt cctcttccta caaaaggtgt
     2281 ggcgtggcac cctggcccgc atgcggtaca agaggaccaa ggcagctctg acaataatca
     2341 ggtactaccg gcgctataaa gtgaagtcgt acatccacga ggtagccagg cgattccacg
     2401 gggtcaagaa catgagagac tacgggaagc acgtgaagtg gccaacccca cccaaagtcc
     2461 tgcggcgttt tgaggaggcc ctgcagtcga tttttaatag atggagagca tcccaactca
     2521 tcaagaccat acctgcatca gaccttcccc aggtcagggc aaaggttgca gccatggaga
     2581 tgttgaaagg tcaaagggca gaccttgggc tccagagggc ctgggaaggc aactatcttg
     2641 cttcaaagcc agatacacct cagacctcgg gcactttcgt cccagttgct aatgagctga
     2701 aacgcaagga caaatatatg aatgttctct tttcctgtca tgtccgaaag gtgaatcgat
     2761 ttagtaaggt agaagaccga gcaatttttg tcactgaccg tcacctgtat aaaatggacc
     2821 ccactaagca gtacaaggtg atgaagacca tcccactgta caatttgact ggcctgagtg
     2881 tgtccaatgg aaaggaccag cttgtagtgt tccacacaaa agacaacaaa gacctcatcg
     2941 tctgcctctt cagcaaacag ccgacccatg agagccggat tggagaactt gttggagtcc
     3001 tggtgaatca tttcaagagt gagaagcgcc accttcaagt gaacgtcacc aacccggtgc
     3061 agtgcagcct gcatgggaag aaatgcaccg tatccgtgga gacccggctt aaccagccac
     3121 agcctgactt caccaagaac cgctccggct tcatcctcag tgtgcccggg aattgactgc
     3181 tgcacaccgg aggcctggcc caggggagca agagcctggg cctggcacac agcaggccag
     3241 gtcctcggcc tcgccatccc cacatctgtt ccacctcgct caacatccca ggagctcggc
     3301 taatcgctgt ttgccctcta atgccactag aaatcagctt gcaagggcct ccgctgggca
     3361 ggactcctct gccttttctg tggccctgct catgacctgt cctacctggc tttctgcctc
     3421 tgccctgcct ctgctctctc aactttccat actccctgct caggaaacca aagaccctct
     3481 tcagcctgct gggctgacag ctagaccact tcccacccca agcgactgga tggctcctgt
     3541 agttggcagg agtgcagtgg ccactgctga ccccagcaga gggatgagag gcccggagcc
     3601 caggacgcag tttctggatc caaagccaca ttatcttaga ggtttggatc cagcatccgt
     3661 gggcagaggg attggccctg ctttgtgacc cctacctgat gcctccttcc acaacatgat
     3721 tgcagccctt agaacctagc tcagagcccc tcagcacaag ccccgccccc agcagccagc
     3781 caaagccact gggtgagcgg gtacatctgc ggagcccatc cctcagcctc gatcaaccag
     3841 gatccctcct tcccagagcc tgtccctggg agagcttttg ccaccaaggt tctagccctg
     3901 gactttctaa ccacttctct catggagaca ccctgctgct actccaagga ccagtttgct
     3961 taactcacag cccacatcca tggtcatctt aaccttcttt cctgcagatt gccaggttgc
     4021 taatctgctg tcccctctgc tgtaagcaca gtgtcaggac ctagtgagga ggtacaagga
     4081 gcaggccgtg cttggagtgc ccattccccc taaccctctg gctgcgcctc ctcctcactg
     4141 gagacccgga actctgagag agccaaagca cacaggaccc agcagtgtgg gttagacaaa
     4201 gctgcagcta agatcgggga gtcctggcac tgcaggccag gccagggtcc ccacctaagc
     4261 cacataatct gcctgccgga gcctggcccc cgagccccct cctgggaaag tgctgcccat
     4321 ttgccagtgt ctgcccagga ggaagggcat ctgcttcaga ggccttcctg agacccctgc
     4381 tcccagcctc agctggtaag gcctctgggt ggcacaggct tgctgtgggg aagcccaaca
     4441 cggaaagttt gcaagaggcg agaggtttgt aggaggcgag cgagccacag cgctttcaga
     4501 gccaggctca cattttcttc acttttgacc cgactctgct ccctaattct caccctgcca
     4561 ccctaaccca ccaagtgcct atgcgctacc tcctgtgcct tggcccgggc ctgagggagt
     4621 cacctggctg gccacggtgg ttccagcacc tggtctccta acccttttgc agagctgtgg
     4681 ggacagggac gtttacactg caggcagttt gcaacaaaac tcctgttgcc atgctgccct
     4741 cgagaggcgt tctcatcccc caagcctggt gagctgccag ttgtgcggac ctgacggagc
     4801 cacgtgactg gaaccacgtg actggaacca cgtgactgga acttcacctt cccaccccac
     4861 ttaccgcccc agcgtgttgc gttacactag acatgctaag tgtgttcata cacaccaaag
     4921 cagttatgcc aaaagagtcg cgggtcagaa gggatggctc ccctcccacc ctctgatgta
     4981 gtctgggacc cctggcccag gccagcacct cccactgagg gctgccctgt ccacgagcac
     5041 tttcttatgt cctaaaagtc agcgtgtggc cactgaagga cctggaatta gaggtgtgga
     5101 tgatcacagt aagagctcgg gagaggacac agtgattgta tgcatggagt aggggtctct
     5161 tgagttcatg aaatgcagtt tatggtttgg tgcatatatt cctattttcc attaaattaa
     5221 ctttatttct aaagcatatt ttgatttacc atcaagagca ataaagcatt aaatcttaaa
     5281 aaaaaaaaaa aaaaaaaaaa aaa
//
