LOCUS       NM_001163736            3841 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus myosin XIX (Myo19), mRNA.
ACCESSION   NM_001163736 XM_001081070 XM_573168
VERSION     NM_001163736.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3841)
  AUTHORS   Hawthorne,J.L., Mehta,P.R., Singh,P.P., Wong,N.Q. and Quintero,O.A.
  TITLE     Positively charged residues within the MYO19 MyMOMA domain are
            essential for proper localization of MYO19 to the mitochondrial
            outer membrane
  JOURNAL   Cytoskeleton (Hoboken) 73 (6), 286-299 (2016)
   PUBMED   27126804
REFERENCE   2  (bases 1 to 3841)
  AUTHORS   Rohn,J.L., Patel,J.V., Neumann,B., Bulkescher,J., Mchedlishvili,N.,
            McMullan,R.C., Quintero,O.A., Ellenberg,J. and Baum,B.
  TITLE     Myo19 ensures symmetric partitioning of mitochondria and coupling
            of mitochondrial segregation to cell division
  JOURNAL   Curr Biol 24 (21), 2598-2605 (2014)
   PUBMED   25447992
REFERENCE   3  (bases 1 to 3841)
  AUTHORS   Lu,Z., Ma,X.N., Zhang,H.M., Ji,H.H., Ding,H., Zhang,J., Luo,D.,
            Sun,Y. and Li,X.D.
  TITLE     Mouse myosin-19 is a plus-end-directed, high-duty ratio molecular
            motor
  JOURNAL   J Biol Chem 289 (26), 18535-18548 (2014)
   PUBMED   24825904
REFERENCE   4  (bases 1 to 3841)
  AUTHORS   Adikes,R.C., Unrath,W.C., Yengo,C.M. and Quintero,O.A.
  TITLE     Biochemical and bioinformatic analysis of the myosin-XIX motor
            domain
  JOURNAL   Cytoskeleton (Hoboken) 70 (5), 281-295 (2013)
   PUBMED   23568824
REFERENCE   5  (bases 1 to 3841)
  AUTHORS   Quintero,O.A., DiVito,M.M., Adikes,R.C., Kortan,M.B., Case,L.B.,
            Lier,A.J., Panaretos,N.S., Slater,S.Q., Rengarajan,M., Feliu,M. and
            Cheney,R.E.
  TITLE     Human Myo19 is a novel myosin that associates with mitochondria
  JOURNAL   Curr Biol 19 (23), 2008-2013 (2009)
   PUBMED   19932026
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On or before Aug 1, 2009 this sequence version replaced
            XM_573168.2, XM_001081070.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643293.64942.1,
                                           SRR26643290.36442.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-58                JAXUCZ010000010.1  70250582-70250639
            59-186              JAXUCZ010000010.1  70251261-70251388
            187-330             JAXUCZ010000010.1  70252696-70252839
            331-469             JAXUCZ010000010.1  70255066-70255204
            470-618             JAXUCZ010000010.1  70255522-70255670
            619-732             JAXUCZ010000010.1  70257966-70258079
            733-865             JAXUCZ010000010.1  70261805-70261937
            866-935             JAXUCZ010000010.1  70263057-70263126
            936-1038            JAXUCZ010000010.1  70263571-70263673
            1039-1135           JAXUCZ010000010.1  70264235-70264331
            1136-1212           JAXUCZ010000010.1  70264445-70264521
            1213-1303           JAXUCZ010000010.1  70266149-70266239
            1304-1475           JAXUCZ010000010.1  70266589-70266760
            1476-1549           JAXUCZ010000010.1  70268438-70268511
            1550-1671           JAXUCZ010000010.1  70269254-70269375
            1672-1785           JAXUCZ010000010.1  70269530-70269643
            1786-1962           JAXUCZ010000010.1  70269898-70270074
            1963-2115           JAXUCZ010000010.1  70270402-70270554
            2116-2223           JAXUCZ010000010.1  70271454-70271561
            2224-2294           JAXUCZ010000010.1  70272395-70272465
            2295-2398           JAXUCZ010000010.1  70274616-70274719
            2399-2565           JAXUCZ010000010.1  70275787-70275953
            2566-2695           JAXUCZ010000010.1  70276062-70276191
            2696-2781           JAXUCZ010000010.1  70277062-70277147
            2782-3081           JAXUCZ010000010.1  70277942-70278241
            3082-3841           JAXUCZ010000010.1  70279108-70279867
FEATURES             Location/Qualifiers
     source          1..3841
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q26"
     gene            1..3841
                     /gene="Myo19"
                     /gene_synonym="RGD1559961"
                     /note="myosin XIX"
                     /db_xref="GeneID:497974"
                     /db_xref="RGD:1559961"
     exon            1..58
                     /gene="Myo19"
                     /gene_synonym="RGD1559961"
                     /inference="alignment:Splign:2.1.0"
     exon            59..186
                     /gene="Myo19"
                     /gene_synonym="RGD1559961"
                     /inference="alignment:Splign:2.1.0"
     exon            187..330
                     /gene="Myo19"
                     /gene_synonym="RGD1559961"
                     /inference="alignment:Splign:2.1.0"
     CDS             319..3213
                     /gene="Myo19"
                     /gene_synonym="RGD1559961"
                     /codon_start=1
                     /product="unconventional myosin-XIX"
                     /protein_id="NP_001157208.1"
                     /db_xref="GeneID:497974"
                     /db_xref="RGD:1559961"
                     /translation="MHQQVNGHSLGSDTQGRTSLKGDLREFLGGEVPLHQLDDLTKVN
                     PVTLETVLRCLQARYTEDIFYTNAGCTLVALNPFKHIPQLYAPELMQEYHAAPQPQKL
                     KPHIFTVGEQTYRNVKSLIEPINQSIVVSGESGAGKTWTSRCLMKFYAVVAASPTSCE
                     NHKMAERIEERILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQTY
                     LLEKTRVACQAASERNFHIFYQICKGATKEERLQWCLPEGTAFSWLPNPESSLEEDCF
                     EVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNVHFVDSEDEAQPCQLMDGTKGSVRTS
                     ALLLQLPDNMLLESMQIRTIKAGKQQQVFQKPCSRAECDTRRDCLAKLIYARLFDWLV
                     SVINSSICADFSSWTAFIGLLDVYGFESFPDNSLEQLCINYANEKLQQHFVAHYLRAQ
                     QEEYEVEGLEWSFVNYQDNQTCLDLLEGSPISICSLINEECRLNRPSSAAQLQTRIES
                     TLAGRPCLGHNKLSREPSFVVMHFAGPVRYCTAGLVEKNKDPVPPELTGLLQQSQDPL
                     LMMLFPANPEEKTQEELSGQSRAPALTVVSKFKASLEQLLQVLHKTTPHYIRCIKPNS
                     QSQPQTFLQEEVLNQLEACGLVETIHISAAGFPIRVSHQNFMERYKLLTRLRPRTSSG
                     LRSLCPAKGSSEQPLCAKEATLQPLLQDILHALPALIQTATTPSDPAKTAQIPLYCGR
                     TKIFMTDSMLELLECGRAQMLEQCARCIQCGWRRHRLQKQEKQRRAAVIIQAAFRSWL
                     TRKHIRRLHIAATVIKHAWHKWRIRMACLASKELDGMEEKLMPQAPGTLRSSLSPAHT
                     RFLGAIIHLWPLGLVLANSADGMRGFQRKLVAHACLRLPASGPSNKVQTPQQDQAGIT
                     SIRALPQGSIKFHCRKSPLQYADICPDPSASNVTGFNQILLLERHRPVQV"
     exon            331..469
                     /gene="Myo19"
                     /gene_synonym="RGD1559961"
                     /inference="alignment:Splign:2.1.0"
     exon            470..618
                     /gene="Myo19"
                     /gene_synonym="RGD1559961"
                     /inference="alignment:Splign:2.1.0"
     exon            619..732
                     /gene="Myo19"
                     /gene_synonym="RGD1559961"
                     /inference="alignment:Splign:2.1.0"
     exon            733..865
                     /gene="Myo19"
                     /gene_synonym="RGD1559961"
                     /inference="alignment:Splign:2.1.0"
     exon            866..935
                     /gene="Myo19"
                     /gene_synonym="RGD1559961"
                     /inference="alignment:Splign:2.1.0"
     exon            936..1038
                     /gene="Myo19"
                     /gene_synonym="RGD1559961"
                     /inference="alignment:Splign:2.1.0"
     exon            1039..1135
                     /gene="Myo19"
                     /gene_synonym="RGD1559961"
                     /inference="alignment:Splign:2.1.0"
     exon            1136..1212
                     /gene="Myo19"
                     /gene_synonym="RGD1559961"
                     /inference="alignment:Splign:2.1.0"
     exon            1213..1303
                     /gene="Myo19"
                     /gene_synonym="RGD1559961"
                     /inference="alignment:Splign:2.1.0"
     exon            1304..1475
                     /gene="Myo19"
                     /gene_synonym="RGD1559961"
                     /inference="alignment:Splign:2.1.0"
     exon            1476..1549
                     /gene="Myo19"
                     /gene_synonym="RGD1559961"
                     /inference="alignment:Splign:2.1.0"
     exon            1550..1671
                     /gene="Myo19"
                     /gene_synonym="RGD1559961"
                     /inference="alignment:Splign:2.1.0"
     exon            1672..1785
                     /gene="Myo19"
                     /gene_synonym="RGD1559961"
                     /inference="alignment:Splign:2.1.0"
     exon            1786..1962
                     /gene="Myo19"
                     /gene_synonym="RGD1559961"
                     /inference="alignment:Splign:2.1.0"
     exon            1963..2115
                     /gene="Myo19"
                     /gene_synonym="RGD1559961"
                     /inference="alignment:Splign:2.1.0"
     exon            2116..2223
                     /gene="Myo19"
                     /gene_synonym="RGD1559961"
                     /inference="alignment:Splign:2.1.0"
     exon            2224..2294
                     /gene="Myo19"
                     /gene_synonym="RGD1559961"
                     /inference="alignment:Splign:2.1.0"
     exon            2295..2398
                     /gene="Myo19"
                     /gene_synonym="RGD1559961"
                     /inference="alignment:Splign:2.1.0"
     exon            2399..2565
                     /gene="Myo19"
                     /gene_synonym="RGD1559961"
                     /inference="alignment:Splign:2.1.0"
     exon            2566..2695
                     /gene="Myo19"
                     /gene_synonym="RGD1559961"
                     /inference="alignment:Splign:2.1.0"
     exon            2696..2781
                     /gene="Myo19"
                     /gene_synonym="RGD1559961"
                     /inference="alignment:Splign:2.1.0"
     exon            2782..3081
                     /gene="Myo19"
                     /gene_synonym="RGD1559961"
                     /inference="alignment:Splign:2.1.0"
     exon            3082..3841
                     /gene="Myo19"
                     /gene_synonym="RGD1559961"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcctttcca atcggtctgg gccgggacta cacgctgggc gccggggccg tgggaccgaa
       61 attcttggtg gtaaactcga gaggagggag caggagaact ggagaaaact gctctgattc
      121 gatttgactt caaccaggag ttgacgctgc aaagtaataa ccagcattta ctcagctctc
      181 tcgcaggttt cgagatgact tgtgggcgat tcccacacac ctgagtcttc tgctggagtg
      241 atggcctcat gaccaggttg acagacagta ctgccagtgt ctgtgacaca gaactctggc
      301 tgaccacact gaagcacgat gcaccagcag gtgaatggcc acagtttagg ctctgatacc
      361 caaggcagga catccctcaa gggcgaccta agggagttcc tgggtgggga ggtcccactg
      421 caccagctgg atgacctcac caaggtgaat cccgtgacac tggaaacagt cctgaggtgc
      481 ctgcaggccc ggtacacaga agacatattc tataccaatg ctggctgtac cttggtagct
      541 ctgaacccct ttaagcacat ccctcaactc tatgcaccag aactgatgca agagtaccat
      601 gctgcacctc agcctcagaa attaaaaccc cacatcttca cagtgggtga gcagacctac
      661 aggaatgtca agagcttgat tgagccgatc aaccaatcca ttgtggtcag tggagagagc
      721 ggagcaggaa agacatggac atcccgatgc ctgatgaagt tctatgctgt ggtggctgcc
      781 tcacctactt cctgtgagaa ccacaagatg gcagagcgga ttgaagagcg gatcctgaac
      841 tccaaccctg tcatggaagc ttttgggaac gcatgcacac tgaggaataa caacagcagt
      901 cgctttggga agttcatcca gctccagctg aacagagccc aacagatgac aggagctgca
      961 gtccagacct acctcctaga gaaaacccgt gtggcctgtc aggccgccag tgagaggaac
     1021 ttccacatct tctaccagat ttgcaaagga gccaccaagg aagaaaggct ccagtggtgc
     1081 ctccctgagg gaactgcctt ctcctggcta cccaatccag aaagcagtct ggaagaggat
     1141 tgtttcgagg tgaccagaga ggccatgctc catctgggca tcgacacccc cacccagaac
     1201 aacatcttta aggtcctagc tggactactg caccttggca atgtccactt cgttgactca
     1261 gaggatgaag cccagccctg ccaactgatg gatggtacca agggctctgt caggacctca
     1321 gccttgctgc tgcagctccc agacaacatg ctgctggaga gcatgcagat tcgaaccatc
     1381 aaggcaggca agcagcagca ggtgttccag aagccctgct ccagagctga gtgtgacaca
     1441 cgcagagact gtctggccaa actgatctat gcacggctat tcgactggct ggtatctgtg
     1501 atcaacagca gcatctgtgc agacttcagc tcatggactg ccttcatagg tctgctagat
     1561 gtgtacgggt ttgagtcatt tcctgacaac agtctggaac agttgtgcat caattatgcc
     1621 aatgagaagc tacagcagca cttcgtggct cactacctca gggcccagca ggaggaatat
     1681 gaagttgagg gcctggagtg gtcatttgtc aactaccagg acaaccagac ctgtttagat
     1741 ctcctcgaag ggagccccat cagcatctgt tccctcataa atgaggaatg ccgccttaac
     1801 cgtccgagca gtgcagcaca actacagaca cgcattgaga gcacgctggc aggcaggccc
     1861 tgcctgggcc ataacaagct cagccgggag cccagctttg tggtgatgca tttcgcagga
     1921 cctgtacggt actgcacagc gggcctagtg gaaaagaaca aggaccctgt tccccctgag
     1981 ctgactgggc tcctgcagca atcccaagac cccctgctca tgatgctgtt tcctgctaac
     2041 cctgaagaga agacccagga ggagctgtct ggccagagca gggctcctgc attgactgtg
     2101 gtgtccaagt tcaaggcctc actggaacag ctcctgcagg tcctgcataa aacaaccccc
     2161 cactacattc gctgcatcaa gcccaacagc cagagtcagc cgcagacttt cctccaggaa
     2221 gaggtcctga accagttaga ggcctgtggt cttgtggaga ccatccacat cagtgctgct
     2281 ggctttccca tccgggtctc tcaccagaac ttcatggaaa gatataaatt gctaacaaga
     2341 ctccgacctc gtacatcctc tggcctcagg agcctgtgtc ctgccaaagg gtcctctgag
     2401 cagcctctgt gtgccaagga ggccacactg cagcctctac tacaggacat tctccatgct
     2461 ctgccagctt taattcagac agcaaccact cccagtgacc cagctaagac tgcacaaatc
     2521 ccactatact gtggcaggac aaagattttc atgactgact ccatgctaga gcttctggaa
     2581 tgtgggcgtg cccagatgct agagcagtgt gcccgctgca tccagtgtgg ctggaggcga
     2641 caccggctcc aaaagcagga gaagcagagg cgggcggccg tgatcattca ggcagctttt
     2701 cggtcctggt taactcggaa acacatcaga aggttacaca tagctgccac agtcatcaag
     2761 cacgcatggc ataagtggag aatcagaatg gcctgtcttg cctctaaaga actggatggt
     2821 atggaggaaa aactcatgcc tcaggctccc ggtaccctgc gttcctcgct gtccccagca
     2881 cacactaggt tcctgggagc aataatccac ctctggcccc tgggactggt gctagccaac
     2941 tcagctgatg gcatgcgtgg ctttcagagg aaactggtag cccatgcctg ccttcggctt
     3001 cccgcaagcg gccccagcaa caaagtccag acaccacaac aagatcaggc tggtatcaca
     3061 tccatcagag cactgcccca gggctcaata aagttccact gcaggaagtc tccacttcag
     3121 tatgctgaca tctgccctga cccttcagcc tctaatgtta ctggctttaa tcagattctg
     3181 ctgctagaaa gacacaggcc agtccaagtg tgactcttct acccccacct gcctgagtga
     3241 tctttactgc tttgtttcca caagcccttt tcctgccagc tgccttgcca aagacatctg
     3301 atcccacaca caagtgccaa gctattccca cagcaactcc aactgactcc aactgcacgt
     3361 gcaagcagat tccagcctaa gccagggctt catggccaaa gtgccaccct ccagggctat
     3421 ggcctcagca ctggcaggat ctgggggtgc tgggtaccaa gccaggatta gggccacaac
     3481 atcccagctt actgtcttta ggctcagact catcagatgt aactgtccat ccagaatgtc
     3541 actacagcaa gatggacact gggccatcca caagcacttt aaagggccaa gtcaccctaa
     3601 aattggctct agaattttgg ctgggggaaa acttgcatat aattcattaa gggaagaata
     3661 atatttaata aactgattta tttaatgtta ccaaggacaa tgaacaatac agggtcaaga
     3721 gaaccacacc ttaaatttct taacactatc agttttcgat tcaaatggat acacttggta
     3781 tttatgatgt aactctgaac tgtacaagaa ataaaattta gacccaccat ctaaatataa
     3841 a
//
