LOCUS       NM_001399315            1367 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus myomaker, myoblast fusion factor (Mymk), mRNA.
ACCESSION   NM_001399315 XM_039104728
VERSION     NM_001399315.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1367)
  AUTHORS   Leikina,E., Gamage,D.G., Prasad,V., Goykhberg,J., Crowe,M.,
            Diao,J., Kozlov,M.M., Chernomordik,L.V. and Millay,D.P.
  TITLE     Myomaker and Myomerger Work Independently to Control Distinct Steps
            of Membrane Remodeling during Myoblast Fusion
  JOURNAL   Dev Cell 46 (6), 767-780 (2018)
   PUBMED   30197239
REFERENCE   2  (bases 1 to 1367)
  AUTHORS   Gamage,D.G., Leikina,E., Quinn,M.E., Ratinov,A., Chernomordik,L.V.
            and Millay,D.P.
  TITLE     Insights into the localization and function of myomaker during
            myoblast fusion
  JOURNAL   J Biol Chem 292 (42), 17272-17289 (2017)
   PUBMED   28860190
REFERENCE   3  (bases 1 to 1367)
  AUTHORS   Di Gioia,S.A., Connors,S., Matsunami,N., Cannavino,J., Rose,M.F.,
            Gilette,N.M., Artoni,P., de Macena Sobreira,N.L., Chan,W.M.,
            Webb,B.D., Robson,C.D., Cheng,L., Van Ryzin,C.,
            Ramirez-Martinez,A., Mohassel,P., Leppert,M., Scholand,M.B.,
            Grunseich,C., Ferreira,C.R., Hartman,T., Hayes,I.M., Morgan,T.,
            Markie,D.M., Fagiolini,M., Swift,A., Chines,P.S.,
            Speck-Martins,C.E., Collins,F.S., Jabs,E.W., Bonnemann,C.G.,
            Olson,E.N., Carey,J.C., Robertson,S.P., Manoli,I. and Engle,E.C.
  CONSRTM   Moebius Syndrome Research Consortium
  TITLE     A defect in myoblast fusion underlies Carey-Fineman-Ziter syndrome
  JOURNAL   Nat Commun 8, 16077 (2017)
   PUBMED   28681861
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1367)
  AUTHORS   Bi,P., Ramirez-Martinez,A., Li,H., Cannavino,J., McAnally,J.R.,
            Shelton,J.M., Sanchez-Ortiz,E., Bassel-Duby,R. and Olson,E.N.
  TITLE     Control of muscle formation by the fusogenic micropeptide myomixer
  JOURNAL   Science 356 (6335), 323-327 (2017)
   PUBMED   28386024
REFERENCE   5  (bases 1 to 1367)
  AUTHORS   Goh,Q. and Millay,D.P.
  TITLE     Requirement of myomaker-mediated stem cell fusion for skeletal
            muscle hypertrophy
  JOURNAL   Elife 6, e20007 (2017)
   PUBMED   28186492
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1367)
  AUTHORS   Millay,D.P., Sutherland,L.B., Bassel-Duby,R. and Olson,E.N.
  TITLE     Myomaker is essential for muscle regeneration
  JOURNAL   Genes Dev 28 (15), 1641-1646 (2014)
   PUBMED   25085416
REFERENCE   7  (bases 1 to 1367)
  AUTHORS   Millay,D.P., O'Rourke,J.R., Sutherland,L.B., Bezprozvannaya,S.,
            Shelton,J.M., Bassel-Duby,R. and Olson,E.N.
  TITLE     Myomaker is a membrane activator of myoblast fusion and muscle
            formation
  JOURNAL   Nature 499 (7458), 301-305 (2013)
   PUBMED   23868259
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Jan 6, 2022 this sequence version replaced XM_039104728.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760386,
                              SAMEA5760475 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-279               JAXUCZ010000003.1  30795096-30795374   c
            280-394             JAXUCZ010000003.1  30790836-30790950   c
            395-543             JAXUCZ010000003.1  30789824-30789972   c
            544-660             JAXUCZ010000003.1  30787517-30787633   c
            661-1367            JAXUCZ010000003.1  30786443-30787149   c
FEATURES             Location/Qualifiers
     source          1..1367
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p12"
     gene            1..1367
                     /gene="Mymk"
                     /gene_synonym="RGD1306074; Tmem8c"
                     /note="myomaker, myoblast fusion factor"
                     /db_xref="GeneID:296601"
                     /db_xref="RGD:1306074"
     exon            1..279
                     /gene="Mymk"
                     /gene_synonym="RGD1306074; Tmem8c"
                     /inference="alignment:Splign:2.1.0"
     CDS             145..810
                     /gene="Mymk"
                     /gene_synonym="RGD1306074; Tmem8c"
                     /note="transmembrane protein 8C"
                     /codon_start=1
                     /product="protein myomaker"
                     /protein_id="NP_001386244.1"
                     /db_xref="GeneID:296601"
                     /db_xref="RGD:1306074"
                     /translation="MGTVVAKLLLPTLSSLAFLPTVSIATKRRFYMEAMIYLFTMFFV
                     AFSHACDGPGLSVLCFMRRDILEYFSIYGTALSMWVSLMALADFDEPQRSTFTMFGVL
                     TIAVRTYHDHWGYGVYSGPIGTATLIIAVKWLKKMKEKKGLYPDKSIYTQQIGPGLCF
                     GALALMLRFFFEEWDYTYVHSFYHCALAMSFVLLLPKVNKKAGNAGDPAKLTFSTLCC
                     TCV"
     exon            280..394
                     /gene="Mymk"
                     /gene_synonym="RGD1306074; Tmem8c"
                     /inference="alignment:Splign:2.1.0"
     exon            395..543
                     /gene="Mymk"
                     /gene_synonym="RGD1306074; Tmem8c"
                     /inference="alignment:Splign:2.1.0"
     exon            544..660
                     /gene="Mymk"
                     /gene_synonym="RGD1306074; Tmem8c"
                     /inference="alignment:Splign:2.1.0"
     exon            661..1367
                     /gene="Mymk"
                     /gene_synonym="RGD1306074; Tmem8c"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agagcactta agccctcctc gtgggcgctg ccacagctgc ggcaagggtt gctgaagaag
       61 agaagtgggc tctatttttc cctgccctgg agaccaagga ggccttcact accttctccc
      121 ctgccagtgc cttcttcctg gcccatgggg acagttgtag ccaaactgct cctgcctacc
      181 ctcagcagcc tggccttcct ccccacagtg agcattgcta ccaagcggcg tttttacatg
      241 gaggccatga tctatctctt caccatgttc tttgtggcgt tctcccatgc ctgcgacggg
      301 cctggcttgt ccgtgctatg cttcatgcgc cgtgatattc tggagtactt cagcatctat
      361 gggacagccc tgagcatgtg ggtctccctg atggcactgg ccgactttga tgaaccccag
      421 agatcaacct tcacgatgtt tggtgtcctt accattgccg tgcggactta ccatgaccac
      481 tggggctacg gggtgtactc tggtcccata ggcaccgcca ccctcatcat tgcagtaaag
      541 tggctgaaga agatgaaaga gaagaagggt ctgtaccctg acaagagcat ctacacccag
      601 cagataggtc ccggcctctg ctttggggcc ctggccctga tgcttcgctt cttctttgag
      661 gaatgggatt acacctacgt tcacagcttc taccactgcg ccctggccat gtccttcgtc
      721 ctgctgctgc ccaaggtcaa caagaaggct gggaacgcag gggaccccgc caagctgacc
      781 ttctccactc tctgctgcac ttgtgtctga cagtagcccc cctgctccag gcccctgcct
      841 tcctgtctgg cagccctgct gtctctcccg ggatacttcc tacactttcc cagtggaatg
      901 tccatgagga atggcctcct ctgcaccccg agagaccagc agggctgctg cagtcggcga
      961 agtgctgctt agggacccac gaattctgtg ttcaccagtt gcttcactct attcaggaaa
     1021 aaaaagagag agaactttat cccccaaggc tgcataacca taggtgtgcc ttgcagagcc
     1081 ctaggccagt cagtattggc cccaagtcac aacccagcag tgtacacaac agcagcatac
     1141 gggttatcta tttcccaggc cctgcctgcc aggattgtct gcctttccta ggaaactggg
     1201 attgcccttt ctacccctgc ccaggccctg aaagctccca gtttcgggag ctggacccag
     1261 tgagcccagt tccagtctgg acccaggctt ggtgcccctg cctgagtccc atcccttcag
     1321 cagtttttcg gtcgagccac tcacagtaaa ctcttgatca gtcacta
//
