LOCUS       NM_001100885            1099 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus myosin light chain 9 (Myl9), mRNA.
ACCESSION   NM_001100885 XM_001067182 XM_006235401 XM_215905
VERSION     NM_001100885.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1099)
  AUTHORS   Lu,Z., Ma,X.N., Zhang,H.M., Ji,H.H., Ding,H., Zhang,J., Luo,D.,
            Sun,Y. and Li,X.D.
  TITLE     Mouse myosin-19 is a plus-end-directed, high-duty ratio molecular
            motor
  JOURNAL   J Biol Chem 289 (26), 18535-18548 (2014)
   PUBMED   24825904
REFERENCE   2  (bases 1 to 1099)
  AUTHORS   Frobel,J., Cadeddu,R.P., Hartwig,S., Bruns,I., Wilk,C.M.,
            Kundgen,A., Fischer,J.C., Schroeder,T., Steidl,U.G., Germing,U.,
            Lehr,S., Haas,R. and Czibere,A.
  TITLE     Platelet proteome analysis reveals integrin-dependent aggregation
            defects in patients with myelodysplastic syndromes
  JOURNAL   Mol Cell Proteomics 12 (5), 1272-1280 (2013)
   PUBMED   23382103
REFERENCE   3  (bases 1 to 1099)
  AUTHORS   Park,I., Han,C., Jin,S., Lee,B., Choi,H., Kwon,J.T., Kim,D.,
            Kim,J., Lifirsu,E., Park,W.J., Park,Z.Y., Kim,D.H. and Cho,C.
  TITLE     Myosin regulatory light chains are required to maintain the
            stability of myosin II and cellular integrity
  JOURNAL   Biochem J 434 (1), 171-180 (2011)
   PUBMED   21126233
REFERENCE   4  (bases 1 to 1099)
  AUTHORS   Shehadeh,L.A., Webster,K.A., Hare,J.M. and Vazquez-Padron,R.I.
  TITLE     Dynamic regulation of vascular myosin light chain (MYL9) with
            injury and aging
  JOURNAL   PLoS One 6 (10), e25855 (2011)
   PUBMED   22003410
  REMARK    GeneRIF: consistent upregulation of the myosin light chain protein
            (Myl9) with age and injury
REFERENCE   5  (bases 1 to 1099)
  AUTHORS   Szczesna-Cordary,D., Guzman,G., Zhao,J., Hernandez,O., Wei,J. and
            Diaz-Perez,Z.
  TITLE     The E22K mutation of myosin RLC that causes familial hypertrophic
            cardiomyopathy increases calcium sensitivity of force and ATPase in
            transgenic mice
  JOURNAL   J Cell Sci 118 (Pt 16), 3675-3683 (2005)
   PUBMED   16076902
REFERENCE   6  (bases 1 to 1099)
  AUTHORS   Iwai,N., Shimoike,H. and Kinoshita,M.
  TITLE     Genes up-regulated in hypertrophied ventricle
  JOURNAL   Biochem Biophys Res Commun 209 (2), 527-534 (1995)
   PUBMED   7733921
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            [WARNING] On May 7, 2024 this sequence was replaced by
            NM_001100885.3.
            
            On or before Dec 7, 2020 this sequence version replaced
            XM_006235401.2, NM_001100885.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ229855.1, BC158548.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-83                JAXUCZ010000003.1  165742047-165742129
            84-292              JAXUCZ010000003.1  165744784-165744992
            293-454             JAXUCZ010000003.1  165747179-165747340
            455-1099            JAXUCZ010000003.1  165747765-165748409
FEATURES             Location/Qualifiers
     source          1..1099
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q42"
     gene            1..1099
                     /gene="Myl9"
                     /note="myosin light chain 9"
                     /db_xref="GeneID:296313"
                     /db_xref="RGD:1311235"
     exon            1..83
                     /gene="Myl9"
                     /inference="alignment:Splign:2.1.0"
     exon            84..292
                     /gene="Myl9"
                     /inference="alignment:Splign:2.1.0"
     CDS             109..627
                     /gene="Myl9"
                     /note="myosin regulatory light chain 9; myosin, light
                     polypeptide 9, regulatory; myosin, light chain 9,
                     regulatory"
                     /codon_start=1
                     /product="myosin regulatory light polypeptide 9"
                     /protein_id="NP_001094355.2"
                     /db_xref="GeneID:296313"
                     /db_xref="RGD:1311235"
                     /translation="MSSKRAKAKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQN
                     RDGFIDKEDLHDMLASLGKNPTDEYLEGMMNEAPGPINFTMFLTMFGEKLNGTDPEDV
                     IRNAFACFDEEASGFIHEDHLRELLTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFT
                     RILKHGAKDKDD"
     exon            293..454
                     /gene="Myl9"
                     /inference="alignment:Splign:2.1.0"
     exon            455..1099
                     /gene="Myl9"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagctccgga gagcgggcga gctgctgcaa gccagctttc gaagcaccgc agcaacgcca
       61 aggacttttc ttctctgcag cagggaaccc ccaacaccca aagccaagat gtccagcaag
      121 agagccaagg ccaagaccac caagaagagg ccccagaggg ctacgtccaa tgtcttcgct
      181 atgtttgacc agtcccagat ccaggagttt aaggaggcct tcaacatgat tgatcagaac
      241 cgtgatggct tcattgacaa ggaggaccta catgacatgc tggcctccct ggggaagaac
      301 cccacggatg agtacctgga gggtatgatg aacgaggccc cgggacctat caacttcacc
      361 atgttcctca ctatgtttgg ggagaagctg aacggcacag accccgagga cgtgatccgc
      421 aatgcctttg cctgctttga tgaggaagcc tcagggttca tccacgagga ccacctgcgg
      481 gagctgctca ccaccatggg cgaccgattc acggatgagg aggtggacga gatgtaccgt
      541 gaggcgccca ttgataagaa gggcaacttc aactatgtgg agttcactcg catcctcaag
      601 cacggcgcca aggacaaaga cgactaggct cttcttagct gtcccaatgc ctacacccca
      661 tcccagtcac ctcctcaaca catacactct accctcccca tgaggagtta gggtcccggc
      721 tcccagggca ggaaatgagc cattaagacg cacagggtga ggcaggggtt ccaccacgga
      781 cccaggcact agaggaaggg ccacagtggg gaggtgagcc aagggtgggg ccagctagca
      841 ccaaagtgaa ggaagccact gaagatggcc accctcagcc atgccctccc attccagggc
      901 taccctgagg aagaaaacac ccatgttctg gtgttggaca ctaattccca gcatccccac
      961 aaaggtacac acccattcac catgtccctt cagaggatga cagtctgcac ttacacctat
     1021 ggagttgtcc cagcacaccc agaatgcata gagggacgct gcctgaggga caaattctct
     1081 aatacaaggc tgagcacca
//
