LOCUS       NM_001109484             677 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus myosin light chain 6 (Myl6), mRNA.
ACCESSION   NM_001109484 NM_001100983 XM_001065562
VERSION     NM_001109484.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 677)
  AUTHORS   Zanivan,S., Maione,F., Hein,M.Y., Hernandez-Fernaud,J.R.,
            Ostasiewicz,P., Giraudo,E. and Mann,M.
  TITLE     SILAC-based proteomics of human primary endothelial cell
            morphogenesis unveils tumor angiogenic markers
  JOURNAL   Mol Cell Proteomics 12 (12), 3599-3611 (2013)
   PUBMED   23979707
REFERENCE   2  (bases 1 to 677)
  AUTHORS   Revenu,C., Ubelmann,F., Hurbain,I., El-Marjou,F., Dingli,F.,
            Loew,D., Delacour,D., Gilet,J., Brot-Laroche,E., Rivero,F.,
            Louvard,D. and Robine,S.
  TITLE     A new role for the architecture of microvillar actin bundles in
            apical retention of membrane proteins
  JOURNAL   Mol Biol Cell 23 (2), 324-336 (2012)
   PUBMED   22114352
REFERENCE   3  (bases 1 to 677)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   4  (bases 1 to 677)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   5  (bases 1 to 677)
  AUTHORS   Kesimer,M., Scull,M., Brighton,B., DeMaria,G., Burns,K., O'Neal,W.,
            Pickles,R.J. and Sheehan,J.K.
  TITLE     Characterization of exosome-like vesicles released from human
            tracheobronchial ciliated epithelium: a possible role in innate
            defense
  JOURNAL   FASEB J 23 (6), 1858-1868 (2009)
   PUBMED   19190083
REFERENCE   6  (bases 1 to 677)
  AUTHORS   Fu,Z.Y., Xie,B.T., Ma,Y.T. and Gong,Z.X.
  TITLE     Preparation of monoclonal antibodies against human ventricular
            myosin light chain 1 (HVMLC1) for functional studies
  JOURNAL   Acta Biochim Biophys Sin (Shanghai) 38 (9), 625-632 (2006)
   PUBMED   16953301
REFERENCE   7  (bases 1 to 677)
  AUTHORS   Florea,L., Di Francesco,V., Miller,J., Turner,R., Yao,A.,
            Harris,M., Walenz,B., Mobarry,C., Merkulov,G.V., Charlab,R.,
            Dew,I., Deng,Z., Istrail,S., Li,P. and Sutton,G.
  TITLE     Gene and alternative splicing annotation with AIR
  JOURNAL   Genome Res 15 (1), 54-66 (2005)
   PUBMED   15632090
REFERENCE   8  (bases 1 to 677)
  AUTHORS   Iwai,N., Shimoike,H. and Kinoshita,M.
  TITLE     Genes up-regulated in hypertrophied ventricle
  JOURNAL   Biochem Biophys Res Commun 209 (2), 527-534 (1995)
   PUBMED   7733921
REFERENCE   9  (bases 1 to 677)
  AUTHORS   Hailstones,D.L. and Gunning,P.W.
  TITLE     Characterization of human myosin light chains 1sa and 3nm:
            implications for isoform evolution and function
  JOURNAL   Mol Cell Biol 10 (3), 1095-1104 (1990)
   PUBMED   2304459
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474104.2.
            
            On or before Aug 31, 2021 this sequence version replaced
            NM_001100983.2, XM_001065562.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5756307,
                              SAMEA5760383 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..677
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q11"
     gene            1..677
                     /gene="Myl6"
                     /gene_synonym="LC17; MLC-3; Myl6l"
                     /note="myosin light chain 6"
                     /db_xref="GeneID:685867"
                     /db_xref="RGD:1589019"
     exon            1..71
                     /gene="Myl6"
                     /gene_synonym="LC17; MLC-3; Myl6l"
                     /inference="alignment:Splign:2.1.0"
     CDS             69..524
                     /gene="Myl6"
                     /gene_synonym="LC17; MLC-3; Myl6l"
                     /note="myosin, light chain 6, alkali, smooth muscle and
                     non-muscle; myosin, light polypeptide 6, alkali, smooth
                     muscle and non-muscle-like; non-muscle myosin alkali light
                     chain; myosin light chain 3; myosin light chain alkali 3;
                     smooth muscle and nonmuscle myosin light chain alkali 6;
                     myosin light chain A3; 17 kDa myosin light chain"
                     /codon_start=1
                     /product="myosin light polypeptide 6"
                     /protein_id="NP_001102954.1"
                     /db_xref="GeneID:685867"
                     /db_xref="RGD:1589019"
                     /translation="MCDFTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPT
                     NAEVLKVLGNPKSDEMNVKVLDFEHFLPMLQTVAKNKDQGTYEDYVEGLRVFDKEGNG
                     TVMGAEIRHVLVTLGEKMTEEEVEMLVAGHEDSNGCINYEELVRMVLNG"
     exon            72..99
                     /gene="Myl6"
                     /gene_synonym="LC17; MLC-3; Myl6l"
                     /inference="alignment:Splign:2.1.0"
     exon            100..243
                     /gene="Myl6"
                     /gene_synonym="LC17; MLC-3; Myl6l"
                     /inference="alignment:Splign:2.1.0"
     exon            244..417
                     /gene="Myl6"
                     /gene_synonym="LC17; MLC-3; Myl6l"
                     /inference="alignment:Splign:2.1.0"
     exon            418..495
                     /gene="Myl6"
                     /gene_synonym="LC17; MLC-3; Myl6l"
                     /inference="alignment:Splign:2.1.0"
     exon            496..677
                     /gene="Myl6"
                     /gene_synonym="LC17; MLC-3; Myl6l"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggttggggtt gggtcccgag tcggagccat tacagccggc aaaggtcccg catagctcag
       61 cagccaagat gtgtgacttc accgaggacc agaccgcaga attcaaggag gctttccagc
      121 tgtttgaccg aacaggcgat ggcaagatcc tgtacagcca gtgtggggat gtgatgcggg
      181 ccctgggcca gaaccctacc aacgccgagg tgctcaaggt cctggggaac cccaagagcg
      241 atgagatgaa tgtgaaggtg ctggactttg agcacttcct gcccatgctg cagactgtgg
      301 ccaagaacaa ggaccaagga acctacgagg attatgttga aggccttcgt gtgtttgaca
      361 aagaagggaa tggcactgtc atgggtgctg aaatccgtca tgtcctagtc acactggggg
      421 agaagatgac agaggaagaa gtcgagatgc tagtggcggg gcatgaggac agcaacggtt
      481 gcattaacta tgaagagctt gtccggatgg tgctgaatgg ctgaggacat ttacgtgtct
      541 cgagcctgct ccttgcccag tgtgagattc ctgtgtggcc ccagaggctc cctaatcaca
      601 gcaccttgcc tgtctggttt cttttggatg atgtttgcct tcaccaaata aaacttgctc
      661 tctgtgctct cttttgg
//
