LOCUS       NM_013194               7208 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus myosin, heavy chain 9 (Myh9), transcript variant
            2, mRNA.
ACCESSION   NM_013194
VERSION     NM_013194.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 7208)
  AUTHORS   Ismail,T.M., Gross,S.R., Lancaster,T., Rudland,P.S. and
            Barraclough,R.
  TITLE     The Role of the C-Terminal Lysine of S100P in S100P-Induced Cell
            Migration and Metastasis
  JOURNAL   Biomolecules 11 (10), 1471 (2021)
   PUBMED   34680103
  REMARK    GeneRIF: The Role of the C-Terminal Lysine of S100P in
            S100P-Induced Cell Migration and Metastasis.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7208)
  AUTHORS   Wang,G., Wang,T., Hu,Y., Wang,J., Wang,Y., Zhang,Y., Li,F., Liu,W.,
            Sun,Y., Yu,B. and Kou,J.
  TITLE     NMMHC IIA triggers neuronal autophagic cell death by promoting
            F-actin-dependent ATG9A trafficking in cerebral
            ischemia/reperfusion
  JOURNAL   Cell Death Dis 11 (6), 428 (2020)
   PUBMED   32513915
  REMARK    GeneRIF: NMMHC IIA triggers neuronal autophagic cell death by
            promoting F-actin-dependent ATG9A trafficking in cerebral
            ischemia/reperfusion.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 7208)
  AUTHORS   Kang,J.S., Lee,S.J., Lee,J.H., Kim,J.H., Son,S.S., Cha,S.K.,
            Lee,E.S., Chung,C.H. and Lee,E.Y.
  TITLE     Angiotensin II-mediated MYH9 downregulation causes structural and
            functional podocyte injury in diabetic kidney disease
  JOURNAL   Sci Rep 9 (1), 7679 (2019)
   PUBMED   31118506
  REMARK    GeneRIF: Angiotensin II-mediated MYH9 downregulation causes
            structural and functional podocyte injury in diabetic kidney
            disease.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 7208)
  AUTHORS   Miserey-Lenkei,S., Bousquet,H., Pylypenko,O., Bardin,S.,
            Dimitrov,A., Bressanelli,G., Bonifay,R., Fraisier,V., Guillou,C.,
            Bougeret,C., Houdusse,A., Echard,A. and Goud,B.
  TITLE     Coupling fission and exit of RAB6 vesicles at Golgi hotspots
            through kinesin-myosin interactions
  JOURNAL   Nat Commun 8 (1), 1254 (2017)
   PUBMED   29093437
  REMARK    GeneRIF: Results suggest that coupling between actin and
            microtubule cytoskeletons driven by Myosin II and KIF20A ensures
            the spatial coordination between RAB6-positive vesicles fission
            from Golgi/trans-Golgi network membranes and their exit along
            microtubules.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 7208)
  AUTHORS   Encarnacao,M., Espada,L., Escrevente,C., Mateus,D., Ramalho,J.,
            Michelet,X., Santarino,I., Hsu,V.W., Brenner,M.B., Barral,D.C. and
            Vieira,O.V.
  TITLE     A Rab3a-dependent complex essential for lysosome positioning and
            plasma membrane repair
  JOURNAL   J Cell Biol 213 (6), 631-640 (2016)
   PUBMED   27325790
REFERENCE   6  (bases 1 to 7208)
  AUTHORS   Maupin,P., Phillips,C.L., Adelstein,R.S. and Pollard,T.D.
  TITLE     Differential localization of myosin-II isozymes in human cultured
            cells and blood cells
  JOURNAL   J Cell Sci 107 (Pt 11), 3077-3090 (1994)
   PUBMED   7699007
REFERENCE   7  (bases 1 to 7208)
  AUTHORS   Murakami,N., Trenkner,E. and Elzinga,M.
  TITLE     Changes in expression of nonmuscle myosin heavy chain isoforms
            during muscle and nonmuscle tissue development
  JOURNAL   Dev Biol 157 (1), 19-27 (1993)
   PUBMED   8482409
REFERENCE   8  (bases 1 to 7208)
  AUTHORS   Toothaker,L.E., Gonzalez,D.A., Tung,N., Lemons,R.S., Le Beau,M.M.,
            Arnaout,M.A., Clayton,L.K. and Tenen,D.G.
  TITLE     Cellular myosin heavy chain in human leukocytes: isolation of 5'
            cDNA clones, characterization of the protein, chromosomal
            localization, and upregulation during myeloid differentiation
  JOURNAL   Blood 78 (7), 1826-1833 (1991)
   PUBMED   1912569
REFERENCE   9  (bases 1 to 7208)
  AUTHORS   Shull,M.M., Pugh,D.G. and Lingrel,J.B.
  TITLE     Characterization of the human Na,K-ATPase alpha 2 gene and
            identification of intragenic restriction fragment length
            polymorphisms
  JOURNAL   J Biol Chem 264 (29), 17532-17543 (1989)
   PUBMED   2477373
REFERENCE   10 (bases 1 to 7208)
  AUTHORS   Araki,W., Ohno,K., Matsunaga,K., Nakamura,H., Sugimoto,C. and
            Shimada,T.
  TITLE     [Two sisters with pseudoidiopathic hypoparathyroidism presenting
            extensive intracranial calcification]
  JOURNAL   Nihon Naika Gakkai Zasshi 78 (1), 81-82 (1989)
   PUBMED   2732579
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Apr 9, 2015 this sequence version replaced NM_013194.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. This RefSeq is similar to NM_001305877.1 from
            GeneID:100911597. This duplication of this locus may be the result
            of an assembly error. Proper placement of this gene is thought to
            be at GeneID:100911597.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U31463.1, SRR26643429.27918.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760386,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-354               JAXUCZ010000007.1  111276574-111276927 c
            355-511             JAXUCZ010000007.1  111271780-111271936 c
            512-539             JAXUCZ010000007.1  111260009-111260036 c
            540-633             JAXUCZ010000007.1  111259137-111259230 c
            634-726             JAXUCZ010000007.1  111255640-111255732 c
            727-790             JAXUCZ010000007.1  111255125-111255188 c
            791-889             JAXUCZ010000007.1  111254458-111254556 c
            890-1033            JAXUCZ010000007.1  111254038-111254181 c
            1034-1129           JAXUCZ010000007.1  111253178-111253273 c
            1130-1248           JAXUCZ010000007.1  111252112-111252230 c
            1249-1401           JAXUCZ010000007.1  111250805-111250957 c
            1402-1575           JAXUCZ010000007.1  111249828-111250001 c
            1576-1749           JAXUCZ010000007.1  111248440-111248613 c
            1750-1864           JAXUCZ010000007.1  111246741-111246855 c
            1865-2058           JAXUCZ010000007.1  111244855-111245048 c
            2059-2180           JAXUCZ010000007.1  111244630-111244751 c
            2181-2250           JAXUCZ010000007.1  111243376-111243445 c
            2251-2411           JAXUCZ010000007.1  111241181-111241341 c
            2412-2520           JAXUCZ010000007.1  111240377-111240485 c
            2521-2652           JAXUCZ010000007.1  111239318-111239449 c
            2653-2859           JAXUCZ010000007.1  111238637-111238843 c
            2860-2997           JAXUCZ010000007.1  111238070-111238207 c
            2998-3121           JAXUCZ010000007.1  111237440-111237563 c
            3122-3293           JAXUCZ010000007.1  111236828-111236999 c
            3294-3506           JAXUCZ010000007.1  111234960-111235172 c
            3507-3651           JAXUCZ010000007.1  111234329-111234473 c
            3652-3858           JAXUCZ010000007.1  111233101-111233307 c
            3859-3963           JAXUCZ010000007.1  111232835-111232939 c
            3964-4116           JAXUCZ010000007.1  111232520-111232672 c
            4117-4365           JAXUCZ010000007.1  111232111-111232359 c
            4366-4578           JAXUCZ010000007.1  111230815-111231027 c
            4579-4791           JAXUCZ010000007.1  111230497-111230709 c
            4792-4953           JAXUCZ010000007.1  111230082-111230243 c
            4954-5082           JAXUCZ010000007.1  111229045-111229173 c
            5083-5171           JAXUCZ010000007.1  111228058-111228146 c
            5172-5295           JAXUCZ010000007.1  111227857-111227980 c
            5296-5504           JAXUCZ010000007.1  111227351-111227559 c
            5505-5613           JAXUCZ010000007.1  111226794-111226902 c
            5614-5786           JAXUCZ010000007.1  111226538-111226710 c
            5787-7208           JAXUCZ010000007.1  111224291-111225712 c
FEATURES             Location/Qualifiers
     source          1..7208
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..7208
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /note="myosin, heavy chain 9"
                     /db_xref="GeneID:25745"
                     /db_xref="RGD:3140"
     exon            1..354
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     CDS             22..5904
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /note="nonmuscle myosin IIA; myosin, heavy chain 9,
                     non-muscle-like 1; myosin heavy chain 9-like 1"
                     /codon_start=1
                     /product="myosin-9"
                     /protein_id="NP_037326.2"
                     /db_xref="GeneID:25745"
                     /db_xref="RGD:3140"
                     /translation="MAQQAADKYLYVDKNFINNPLAQADWAAKKLVWVPSTKNGFEPA
                     SLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLK
                     ERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVDMYKGKKRHEMPPHIYAITDTAYRS
                     MMQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKSKKDQGELERQLLQANPIL
                     EAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHI
                     FYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIPGQQDKDMFQETMEAMRIMGIPED
                     EQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTP
                     RIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDKTKRQGASFIGI
                     LDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDL
                     QPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVVQEQGTHPKFQKPKQLKDKA
                     DFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRIIGLDQV
                     AGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGK
                     LDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKGFMDGKQAC
                     VLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKA
                     FAKRQQQLTAMKVLQRNCAAYLRLRNWQWWRLFTKVKPLLNSIRHEDELLAKEAELTK
                     VREKHLAAENRLTEMETMQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELE
                     EICHDLEARVEEEEERCQYLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAK
                     LKKLEEDQIIMEDQNCKLAKEKKLLEDRVAEFTTNLMEEEEKSKSLAKLKNKHEAMIT
                     DLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAA
                     LARVEEEAAQKNMALKKIRELETQISELQEDLESERACRNKAEKQKRDLGEELEALKT
                     ELEDTLDSTAAQQELRSKREQEVSILKKTLEDEAKTHEAQIQEMRQKHSQAVEELAEQ
                     LEQTKRVKATLEKAKQTLENERGELANEVKALLQGKGDSEHKRKKVEAQLQELQVKFS
                     EGERVRTELADKVSKLQVELDSVTGLLNQSDSKSSKLTKDFSALESQLQDTQELLQEE
                     NRQKLSLSTKLKQMEDEKNSFREQLEEEEEAKRNLEKQIATLHAQVTDMKKKMEDGVG
                     CLETAEEAKRRLQKDLEGLSQRLEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSV
                     SNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAE
                     LERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATE
                     DAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSIAMA
                     ARKKLEMDLKDLEAHIDTANKNREEAIKQLRKLQAQMKDCMRELDDTRASREEILAQA
                     KENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRR
                     LEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLE
                     RQNKELKAKLQEMESAVKSKYKASIAALEAKIAQLEEQLDNETKERQAASKQVRRAEK
                     KLKDVLLQVEDERRNAEQFKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQREL
                     EDATETADAMNREVSSLKNKLRRGDMPFVVTRRIVRKGTGDCSDEEVDGKADGADAKA
                     AE"
     exon            355..511
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            512..539
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            540..633
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            634..726
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            727..790
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            791..889
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            890..1033
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            1034..1129
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            1130..1248
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            1249..1401
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            1402..1575
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            1576..1749
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            1750..1864
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            1865..2058
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            2059..2180
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            2181..2250
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            2251..2411
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            2412..2520
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            2521..2652
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            2653..2859
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            2860..2997
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            2998..3121
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            3122..3293
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            3294..3506
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            3507..3651
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            3652..3858
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            3859..3963
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            3964..4116
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            4117..4365
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            4366..4578
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            4579..4791
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            4792..4953
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            4954..5082
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            5083..5171
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            5172..5295
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            5296..5504
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            5505..5613
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            5614..5786
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
     exon            5787..7208
                     /gene="Myh9"
                     /gene_synonym="Myh9l1; NMIIA"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aggtcctggc cataagtcac catggcccag caggctgcag acaagtacct ctatgtggat
       61 aaaaacttca tcaataaccc gctggcccag gccgactggg ctgccaagaa gctggtatgg
      121 gtgccttcca ccaagaatgg ctttgaacca gccagcctta aggaggaggt gggagaagag
      181 gccattgtgg agctggtgga gaatgggaag aaggtgaagg tgaacaagga tgatatccag
      241 aagatgaacc cacccaagtt ctccaaggtg gaggacatgg cagagctcac gtgcctcaac
      301 gaagcctcgg tgctgcacaa cctcaaggag cgatactact cagggctcat ctatacctat
      361 tcaggcctgt tctgtgtggt cattaatcct tataagaacc tgcctatcta ctcagaggag
      421 atcgtggaca tgtacaaggg caagaagagg cacgagatgc cgccccacat ctatgccatc
      481 acagacactg cctacaggag catgatgcag gaccgagaag atcagtccat cctttgcacg
      541 ggtgagtctg gagcaggcaa gacagagaac accaagaaag tcatccagta cctggcacat
      601 gtggcctcct cacacaagag caagaaggac cagggggagc tggagcgcca actgctgcag
      661 gccaacccta tcctagaggc ctttggaaac gccaagacgg tgaagaatga caactcttca
      721 cgatttggta aattcattcg tatcaacttt gatgtcaacg gctacatcgt tggggccaac
      781 attgagactt atcttctgga gaaatctcgt gctatccgcc aagccaagga ggaaagaacc
      841 ttccacattt tctattacct gctgtctggg gccggagagc acctgaagac tgatctcctg
      901 ttggagccat acaataaata ccgcttcctg tccaatgggc atgtcaccat cccagggcag
      961 caggacaagg acatgttcca ggagacaatg gaggccatga ggattatggg tatcccagag
     1021 gatgagcaga tgggcttgct gcgggtcatc tctggcgtcc ttcagcttgg caacattgtc
     1081 ttcaagaagg aacggaacac tgaccaggcg tccatgccag ataacacagc tgctcaaaag
     1141 gtgtcccacc tcctggggat caatgtgacc gacttcacca gaggcatcct taccccgcgc
     1201 atcaaggtgg gcagagacta tgtgcagaag gcacagacta aagagcaggc tgactttgcc
     1261 atcgaggctt tggccaaggc tacctacgag cggatgttcc gctggctggt gcttcgcatt
     1321 aacaaagctc tggacaagac caagaggcag ggcgcctcat ttatcgggat cctggacatc
     1381 gctggcttcg agatctttga tctgaactcc ttcgagcaac tttgcatcaa ctataccaac
     1441 gagaagctgc agcagctgtt caaccacacc atgttcatcc tggagcagga ggagtaccag
     1501 cgagagggca tcgagtggaa cttcatcgac tttggccttg acctgcagcc ttgcatcgac
     1561 ctcattgaga agccggcggg tcccccaggc atcctggccc tgttagatga ggaatgttgg
     1621 ttccctaaag ccactgacaa gagcttcgtg gagaaggtgg tgcaggagca gggcacccac
     1681 cccaagttcc agaagcccaa gcaactgaag gacaaggctg atttctgcat catccactat
     1741 gcaggcaagg tggactataa ggccgatgag tggctgatga agaacatgga ccctctgaac
     1801 gacaacattg ccaccctgct tcaccagtcc tcagacaagt ttgtctctga gctgtggaag
     1861 gatgtggatc gaatcattgg cttggaccag gtggctggaa tgtctgagac agcgctaccc
     1921 ggtgccttca agactcggaa gggcatgttc cgtactgtgg ggcagctgta caaggagcag
     1981 ctggccaagc tcatggccac actgaggaat accaatccca actttgtccg ctgcatcatt
     2041 cccaaccacg agaagaaggc cggcaaactg gacccacacc tggtgctgga ccagttacgc
     2101 tgcaatggcg tccttgaagg catccgaatc tgccgccagg gctttcccaa cagagtggtc
     2161 ttccaggagt tccggcagag gtatgagatc ctcacaccta actccattcc gaagggcttc
     2221 atggatggga agcaggcgtg tgtgctcatg atcaaagcct tggagcttga cagcaacctg
     2281 taccgcatcg gccagagcaa agtgttcttc cgggccggag tcctagctca cctggaggaa
     2341 gagcgggacc tgaagatcac tgatgtcatc attggcttcc aggcctgctg cagaggctac
     2401 ctggccagga aggcctttgc caagaggcag cagcagctga ctgccatgaa ggtcctacag
     2461 aggaactgtg ctgcatacct cagactccgc aactggcagt ggtggaggct cttcaccaag
     2521 gtcaagcccc tgctgaactc aataaggcat gaggatgagc ttttagccaa ggaggcggaa
     2581 ctgacaaaag ttcgagagaa gcatctggct gcagagaaca ggctgacaga gatggagact
     2641 atgcagtctc agctcatggc agagaagttg cagcttcagg agcagctgca ggcggaaaca
     2701 gagttgtgtg ccgaggctga ggagctccgg gcccgcctga cagcgaagaa gcaggagttg
     2761 gaggagatct gccatgacct ggaggccagg gtagaggagg aggaggagcg ctgccagtat
     2821 ctgcaggcag agaagaagaa gatgcagcag aacatccagg aactcgagga gcagctggag
     2881 gaggaggaga gtgcccggca gaagctgcag cttgagaagg tgaccactga ggccaagctg
     2941 aagaaactgg aggaggacca gatcatcatg gaggatcaaa actgcaaact ggccaaggag
     3001 aagaagctgc tggaagacag agtagctgaa tttactacaa acctcatgga agaggaggag
     3061 aagtccaaga gcctggccaa actcaagaac aagcacgagg cgatgatcac cgacctggaa
     3121 gagcgccttc gtagggagga gaagcaaagg caggagttgg agaagacccg ccgcaagcta
     3181 gagggagact ccacagacct cagcgaccag attgctgagc tccaggcgca gatcgcagag
     3241 ctcaagatgc agctggccaa gaaggaggag gaattgcagg ctgccttggc cagagtggaa
     3301 gaagaagctg ctcagaagaa catggccctg aagaagattc gagaactgga aactcagatc
     3361 tctgagctgc aggaagacct ggagtcggag cgagcctgca ggaacaaagc tgagaagcag
     3421 aaacgggatc ttggagaaga gctagaggct ctgaagacag agctggagga cactctggac
     3481 tccaccgctg cccagcagga actgaggtca aagcgtgagc aggaagtgag catcctgaag
     3541 aagactcttg aggatgaggc caagacccat gaggcccaga tccaggagat gaggcagaag
     3601 cactcgcagg ccgtggagga gctggccgag caattggagc agactaagcg ggtaaaagct
     3661 acccttgaga aggcgaagca gaccctggag aatgagcggg gagagctggc caatgaggtg
     3721 aaggccttgc tgcagggcaa gggcgactcg gagcacaagc gcaagaaggt ggaggcgcag
     3781 ctgcaagaac tgcaggtcaa gttcagcgag ggagagcgtg tacggaccga gctggctgac
     3841 aaggtctcca agctgcaggt tgaactggac agcgtgactg gtctccttaa ccagtcggac
     3901 agcaagtcca gcaagcttac aaaggacttc tctgcgctgg agtcccagct ccaggacaca
     3961 caggagctgc tccaggagga gaaccggcag aagctgagcc tcagcaccaa gctcaagcag
     4021 atggaggatg agaaaaactc cttcagagag cagctggagg aggaagagga ggccaagcgc
     4081 aacctggaga agcagatcgc caccctccat gcccaggtga ctgatatgaa gaagaagatg
     4141 gaggacggtg tagggtgcct ggagacagca gaggaggcaa agcggaggct tcagaaggac
     4201 ctggaaggcc tgagccagcg gcttgaggag aaggtggctg cctatgataa gctggagaag
     4261 accaagaccc ggcttcagca ggagctggat gacctgctgg tggacctgga ccaccagcgg
     4321 cagagcgtct ccaacctgga aaagaagcag aagaagtttg accagctcct agctgaggag
     4381 aagaccatct cagccaagta tgctgaggag cgagaccgag ctgaggctga ggcccgtgag
     4441 aaggagacaa aggcactgtc actggcccgg gcacttgagg aggccatgga gcagaaggca
     4501 gagctagaac ggctcaacaa gcagttccgc acggagatgg aggacctcat gagctccaag
     4561 gatgacgtgg gcaagagcgt ccatgagctg gagaagtcca agagggcatt ggagcagcag
     4621 gtcgaggaga tgaagaccca gctggaggag ctggaggatg agcttcaggc cactgaggat
     4681 gccaagctcc gtctggaggt gaacctgcag gccatgaagg cccagtttga gcgggatctg
     4741 cagggccggg atgaacagag cgaggagaag aagaagcagc tggtcagaca ggtgcgggag
     4801 atggaggcgg agctggagga tgagaggaag cagcggtcca ttgccatggc tgctcgcaag
     4861 aaactagaga tggatctgaa ggacctggag gctcacatag acacagccaa caagaaccgg
     4921 gaggaggcca tcaaacagct acggaagctt caggcccaga tgaaggactg catgcgggag
     4981 ctggacgaca cgcgagcctc ccgggaggag atcctggccc aggccaagga gaatgagaag
     5041 aagctcaaga gcatggaggc cgagatgatt cagctgcagg aggaactggc agccgccgag
     5101 cgtgctaaac gccaggccca acaggagcgg gatgagctgg ccgatgagat cgccaacagc
     5161 agtggcaaag gggccctagc attggaggag aagcggcgac tagaggcccg cattgcccag
     5221 ctggaggaag agctggagga ggagcagggc aacacagaac tgatcaacga ccggctgaag
     5281 aaggccaatc tgcagatcga ccaaataaac accgacctga acctggagcg cagccacgcc
     5341 cagaagaacg agaatgcgcg gcagcagctg gaacgccaga acaaggagct caaggccaag
     5401 ctgcaggaga tggagagtgc tgtcaagtcc aaatacaagg cctccatcgc tgccttggag
     5461 gccaagattg cacagctgga ggagcagctg gacaacgaga ccaaggagcg ccaggcagcc
     5521 tccaagcagg tgcgccgggc ggagaagaag ctgaaggatg tgctgctgca agtggaagac
     5581 gagcggagga acgcggagca gttcaaggac caggccgaca aggcatccac tcgcctgaag
     5641 cagcttaagc ggcagctaga ggaggccgag gaggaggccc agcgggccaa tgcctcccgc
     5701 cggaagctgc agcgtgagct ggaggatgcc acagagactg ccgatgctat gaaccgagag
     5761 gtcagctccc tgaagaacaa actgaggcgt ggggacatgc catttgttgt gacccgccga
     5821 attgtccgga aaggcactgg cgactgctca gacgaggagg tcgacggtaa agcagacggg
     5881 gctgatgcca aggcagccga gtagggactt ctgctaccca agacggatgg acagacggct
     5941 ccacctccct tccccagccc tccatacccc tgccttgaga ctgctctgcc catgcccctc
     6001 ttcctcccag gccttcctga gggcattggc ttcctctgct gcagccctgt cagtcttcct
     6061 tgcccttgag aatctgatac caaagagtcc aggctggatg acccgcaagg tcttgcccca
     6121 cttgcctgaa agcacggatg gcgggtgaga aggccggcca tgggagtggc cacaagagtt
     6181 ttctatgaat ctattttttt cttgagataa aggttttgat agctcaggcc ctctagaagt
     6241 gtcaccttac cctgcctttg ctgccagttc ctccccactc cttcctctgc tgttggcaat
     6301 cacacacggt aacctcacac ttgccctttg gccctcttcc ctgggccctt cctggtccag
     6361 aaggagcagt ccagggctta cgcctctgtg ctgggtgcag aacatggggc actctgggaa
     6421 cccccacccc tacccctacc ccctctgggc agcattggtg cctctgctcc tttcaactgt
     6481 aaaaatgtct caagtgcaat gcccctccct cccttgccca gggcagactg tcctggcact
     6541 ggggcaaacc agacagggca tcagggccac tctagaaagg ccagcagcct tccggtggct
     6601 tctcccagca ctctagggga ccaaatatat ttaatggtta agggacttgc agggcccggc
     6661 agccagaata tccaagggct gggcccgccg tgcgctcttg tgcctctcct aggactgggg
     6721 ccaagggtgg ctgagctgca ccacccactc tctatagctt caagtctgcc ttctacagat
     6781 gctttgagag aaaaccaagg ctttattttc ccttcttgta gtaagcgctc tagttgtggg
     6841 tcctcacagc cttgcccctg gagccacgct tagaagagag tagcctgccc tacaatggtc
     6901 tacactggtc gctgagtttc cctgtgctcc tcctcactgt gttataaatg ctgtgattag
     6961 agtccctatg gcaagaaggc tttttttttt ttttttttta aaggagaaac agtcaaatca
     7021 tgaagctaca tatgctagaa aagctctgaa ttcaggtccc agttgctgtc acaggagtga
     7081 gtgggacccg cacccctttt ttatataata caagtgcctt agcatgtgtt gcagctgtca
     7141 ccactacagt aagctggttt acagatgttt ccactgagcg tcacaataaa agagtaccat
     7201 gtcctgct
//
