LOCUS       NM_012604               6035 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Rattus norvegicus myosin heavy chain 3 (Myh3), mRNA.
ACCESSION   NM_012604
VERSION     NM_012604.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6035)
  AUTHORS   Gong,C., Wu,J., Li,H., Luo,C., Ji,G., Guan,X., Liu,J. and Wang,M.
  TITLE     METTL3 achieves lipopolysaccharide-induced myocardial injury via
            m6A-dependent stabilization of Myh3 mRNA
  JOURNAL   Biochim Biophys Acta Mol Cell Res 1870 (7), 119503 (2023)
   PUBMED   37245538
  REMARK    GeneRIF: METTL3 achieves lipopolysaccharide-induced myocardial
            injury via m[6]A-dependent stabilization of Myh3 mRNA.
REFERENCE   2  (bases 1 to 6035)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   3  (bases 1 to 6035)
  AUTHORS   Tajsharghi,H., Kimber,E., Kroksmark,A.K., Jerre,R., Tulinius,M. and
            Oldfors,A.
  TITLE     Embryonic myosin heavy-chain mutations cause distal arthrogryposis
            and developmental myosin myopathy that persists postnatally
  JOURNAL   Arch Neurol 65 (8), 1083-1090 (2008)
   PUBMED   18695058
  REMARK    Erratum:[Arch Neurol. 2008 Dec;65(12):1654]
REFERENCE   4  (bases 1 to 6035)
  AUTHORS   Lechner,B.E., Lim,J.H., Mercado,M.L. and Fallon,J.R.
  TITLE     Developmental regulation of biglycan expression in muscle and
            tendon
  JOURNAL   Muscle Nerve 34 (3), 347-355 (2006)
   PUBMED   16810681
REFERENCE   5  (bases 1 to 6035)
  AUTHORS   Toydemir,R.M., Rutherford,A., Whitby,F.G., Jorde,L.B., Carey,J.C.
            and Bamshad,M.J.
  TITLE     Mutations in embryonic myosin heavy chain (MYH3) cause
            Freeman-Sheldon syndrome and Sheldon-Hall syndrome
  JOURNAL   Nat Genet 38 (5), 561-565 (2006)
   PUBMED   16642020
REFERENCE   6  (bases 1 to 6035)
  AUTHORS   Deng,A.Y. and Rapp,J.P.
  TITLE     Locus for the inducible, but not a constitutive, nitric oxide
            synthase cosegregates with blood pressure in the Dahl
            salt-sensitive rat
  JOURNAL   J Clin Invest 95 (5), 2170-2177 (1995)
   PUBMED   7537756
REFERENCE   7  (bases 1 to 6035)
  AUTHORS   Smith,T.H. and Miller,J.B.
  TITLE     Distinct myogenic programs of embryonic and fetal mouse muscle
            cells: expression of the perinatal myosin heavy chain isoform in
            vitro
  JOURNAL   Dev Biol 149 (1), 16-26 (1992)
   PUBMED   1728586
REFERENCE   8  (bases 1 to 6035)
  AUTHORS   Strehler,E.E., Strehler-Page,M.A., Perriard,J.C., Periasamy,M. and
            Nadal-Ginard,B.
  TITLE     Complete nucleotide and encoded amino acid sequence of a mammalian
            myosin heavy chain gene. Evidence against intron-dependent
            evolution of the rod
  JOURNAL   J Mol Biol 190 (3), 291-317 (1986)
   PUBMED   3783701
REFERENCE   9  (bases 1 to 6035)
  AUTHORS   Periasamy,M., Wydro,R.M., Strehler-Page,M.A., Strehler,E.E. and
            Nadal-Ginard,B.
  TITLE     Characterization of cDNA and genomic sequences corresponding to an
            embryonic myosin heavy chain
  JOURNAL   J Biol Chem 260 (29), 15856-15862 (1985)
   PUBMED   2999140
REFERENCE   10 (bases 1 to 6035)
  AUTHORS   Strehler,E.E., Mahdavi,V., Periasamy,M. and Nadal-Ginard,B.
  TITLE     Intron positions are conserved in the 5' end region of myosin
            heavy-chain genes
  JOURNAL   J Biol Chem 260 (1), 468-471 (1985)
   PUBMED   2981212
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from X04267.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760384,
                              SAMEA5760386 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..6035
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q24"
     gene            1..6035
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /note="myosin heavy chain 3"
                     /db_xref="GeneID:24583"
                     /db_xref="RGD:3138"
     exon            1..24
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            25..82
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            83..294
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     CDS             91..5913
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /note="myosin heavy chain, fast skeletal muscle,
                     embryonic; myosin heavy polypeptide 3; myosin, heavy
                     polypeptide 3, skeletal muscle, embryonic; myosin, heavy
                     chain 3, skeletal muscle, embryonic"
                     /codon_start=1
                     /product="myosin-3"
                     /protein_id="NP_036736.1"
                     /db_xref="GeneID:24583"
                     /db_xref="RGD:3138"
                     /translation="MSSDTEMEVFGIAAPFLRKSEKERIEAQNQPFDAKTYCFVVDSK
                     EEYAKGKIKSSQDGKVTVETEDNRTLVVKPEDVYAMNPPKFDKIEDMAMLTHLNEPAV
                     LYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYTPEVVDGYRGKKRQEAPPHIFSISD
                     NAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLAKKKDSKMKGTLE
                     DQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTF
                     QLKAERSYHIFYQILSNKKPELIELLLITTNPYDYPFISQGEILVASIDDREELLATD
                     SAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKTAYLMGLN
                     SSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQQLDT
                     KLPRQHFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIE
                     WTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQK
                     PKVVKGKAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHLYAT
                     FATTDADGGKKKVAKKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPNETKTP
                     GAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIPEGQFIDSK
                     KACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDERLAKLITRTQAVCRGFLM
                     RVEFQKMMQRRESIFCIQYNIRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEE
                     FQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKF
                     QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHAT
                     ENKVKNLTEELAGLDETIAKLTREKKALQEAHQQTLDDLQAEEDKVNSLSKLKSKLEQ
                     QVDDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEY
                     SQLQSKVEDEQTLSLQLQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEE
                     LSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEATVATLRKKHADSAAEL
                     AEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSVESVSKSKANLEKICRTLEDQLSEARG
                     KNEETQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQIEELKRQL
                     EEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYET
                     DAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERA
                     NSLAAALDKKQRNFDKVLAEWKTKCEESQAELEAALKESRSLSTELFKLKNAYEEALD
                     QLETVKRENKNLEQEIADLTEQIAENGKSIHELEKSRKQMELEKADIQMALEEAEAAL
                     EHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQGALDAEVRSRN
                     EAIRLKKKMEGDLNEIEIQLSHANRQAAETIKHLRSVQGQLKDTQLHLDDALRGQEDL
                     KEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIH
                     TKKKLETDLTQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMK
                     KNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKRNTESVKGLR
                     KYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANVHLTKFRKA
                     QHELEEAEERADIAESQVNKLRAKTRDFTSSRMVVHESEE"
     exon            295..438
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            439..595
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            596..623
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            624..732
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            733..825
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            826..889
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            890..988
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            989..1092
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            1093..1231
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            1232..1350
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            1351..1500
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            1501..1671
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            1672..1978
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            1979..2049
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            2050..2137
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            2138..2255
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            2256..2379
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            2380..2516
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            2517..2772
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            2773..3015
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            3016..3192
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            3193..3338
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            3339..3429
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            3430..3819
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            3820..3946
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            3947..4065
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            4066..4262
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            4263..4446
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            4447..4612
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            4613..4737
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            4738..5046
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            5047..5250
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            5251..5376
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            5377..5547
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            5548..5652
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            5653..5748
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            5749..5886
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     exon            5887..6035
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      6035
                     /gene="Myh3"
                     /gene_synonym="Myhse; RNMHCG"
ORIGIN      
        1 tgcttcactc tgccacagtc agaggtccca taggtccaca gctgctgctg ctgctctctg
       61 ctgtcctgcc ggtgtgactc agccaacact atgagtagcg acaccgagat ggaagtgttt
      121 ggcatagctg cccctttcct ccgaaagtcg gaaaaggaga ggatcgaagc tcagaaccag
      181 ccctttgatg ccaaaaccta ttgctttgtg gttgactcaa aggaagaata tgccaagggg
      241 aaaattaaga gtagccagga tgggaaagtc acggtggaga cagaagacaa caggaccctg
      301 gtggttaaac cagaggacgt gtatgccatg aaccctccca agtttgacaa gatcgaggac
      361 atggccatgc tgacccacct gaacgagcct gctgtgctgt acaacctcaa ggaccgatac
      421 acgtcctgga tgatctacac ctattcaggc ctcttctgtg tcaccgtcaa cccctacaag
      481 tggttgccgg tgtacacccc tgaggtggtg gatggctacc gaggcaaaaa gcgccaggag
      541 gccccgcccc acatcttctc catctctgac aacgcctacc agttcatgct gacggatcgt
      601 gagaaccagt ccatcctgat caccggagaa tccggggccg ggaagacggt gaacaccaag
      661 cgtgtcatcc agtactttgc aacaattgca gccactgggg accttgccaa gaagaaggac
      721 tccaaaatga aggggaccct ggaagatcaa atcatcagcg ccaaccccct gctggaggcc
      781 tttgggaatg ccaagaccgt gaggaatgac aactcttccc gctttggcaa gttcatccgc
      841 atccatttcg gcaccactgg gaagctggcc tctgcagata ttgaaactta tctgctggaa
      901 aagtccagag tcaccttcca gctgaaggct gagagaagct atcacatctt ctaccagatt
      961 ctttccaaca agaagccgga actgatcgag ttgctgctga ttacgaccaa cccttacgac
     1021 tacccattca tcagccaggg tgaaatcctg gtggccagca tcgatgatcg tgaggaactg
     1081 ttggctacag acagtgccat tgacatcctg ggcttcaccc cggaggagaa atctggactc
     1141 tataaactga caggggctgt gatgcattat gggaacatga agttcaagca gaagcagcga
     1201 gaggagcaag ctgagccaga tggcaccgaa gtggctgaca aaacagccta cttgatgggc
     1261 ctgaactctt cagacctcct caaagccttg tgctttccca gagtgaaagt tgggaatgag
     1321 tacgttacaa aaggccaaac tgtggaccag gttcaccatg ctgtgaatgc tctctccaag
     1381 tccgtttatg agaagctgtt cttgtggatg gtcactcgta ttaaccagca gctggacaca
     1441 aagctaccaa gacaacactt cattggggtt ttggacattg cgggttttga aatttttgag
     1501 tataacagcc tggagcagct gtgcatcaac ttcaccaacg agaaactgca acagtttttc
     1561 aaccaccaca tgttcgtgct ggagcaggag gagtacaaga aggaaggcat cgagtggacc
     1621 ttcatcgact tcgggatgga cctggcggcc tgcatcgagc tcatcgagaa gccgatgggc
     1681 atcttctcca tcctggaaga ggagtgcatg ttccccaagg cgacagacac ctccttcaag
     1741 aacaagctgt atgaccagca ccttggaaaa tccaacaact tccagaagcc taaggtggtc
     1801 aaaggcaagg ccgaggccca cttctccctc atccactatg cgggcaccgt ggactacagt
     1861 gtctcgggct ggctggagaa gaacaaggac cccctgaatg agaccgtggt ggggctgtac
     1921 cagaagtctt ccaacagact cctggcccat ctctatgcca ccttcgctac gacagatgct
     1981 gacggtggga agaagaaagt cgctaagaag aaaggctctt ccttccaaac agtgtctgcg
     2041 ctgttcaggg aaaacttgaa caagctgatg tccaatttaa gaaccactca cccacacttt
     2101 gtgcgctgta taatacccaa tgaaaccaag accccagggg ccatggaaca cagcctggtc
     2161 ctgcaccagc tgaggtgtaa cggggtgcta gaaggcatcc gcatctgcag gaaggggttc
     2221 cccaacagga ttctgtatgg agactttaaa cagagatacc gagtgctgaa cgccagtgcc
     2281 atcccggagg gccagttcat tgacagcaag aaagcttgcg agaagctctt ggcttccatt
     2341 gacatcgacc acacacagta caaatttgga cacaccaagg tgttctttaa ggctggcttg
     2401 ctgggaaccc tggaggagat gcgggatgag cgtctggcca aactgatcac tcggacacaa
     2461 gccgtgtgca gagggttcct catgcgtgtg gaattccaga agatgatgca gaggagggaa
     2521 tccatcttct gcatccagta caacatccgc gccttcatga acgtcaagca ctggccctgg
     2581 atgaaactct tcttcaagat caagcccctg ctgaagagcg ccgagacgga gaaggagatg
     2641 gccaccatga aggaggagtt ccagaagacc aaggacgagc tcgccaagtc ggaggcaaag
     2701 aggaaggagc tggaggagaa gctggtcact ctggtacaag agaagaacga cctgcagctc
     2761 caagtacagg cggagagtga gaatttgctg gatgccgagg agcgatgcga ccagctgatc
     2821 aaagccaagt tccagctgga ggccaaaatt aaagaggtga ccgaaagagc tgaggatgag
     2881 gaggagatca acgccgagct cacggccaag aagaggaagc tggaggacga gtgctcggag
     2941 ctgaagaagg acatcgatga ccttgagctg acactggcca aggttgagaa ggagaagcac
     3001 gccacggaga acaaggtaaa aaaccttacc gaagaactgg caggcctgga tgaaactatt
     3061 gcaaagctaa cacgggagaa gaaggccctc caagaggccc accagcagac cctggacgac
     3121 ctccaggctg aggaagacaa ggtcaattct ctgagcaagc tcaagagcaa gctggagcag
     3181 caagtggatg atttggagag ctccctcgaa caagagaaga agctgcgtgt ggacctggaa
     3241 aggaacaaga ggaagctgga gggagacctg aagcttgccc aagagtccat attagatctg
     3301 gagaacgaca agcaacagct ggacgagagg ctcaagaaga aggactttga atatagccag
     3361 ctgcagagca aggtggaaga tgagcagacg ctgagcctcc aacttcagaa gaaaatcaaa
     3421 gagttacagg cccgcattga ggagctggag gaagagatag aggcggagag ggccacccgg
     3481 gccaagacag agaagcagcg cagcgactac gcccgcgagc tggaggagct gagtgaacgt
     3541 ctggaggagg cgggcggtgt cacctctacc cagattgagc tgaacaagaa gcgtgaggct
     3601 gagttcttga agctgcgcag ggacctggag gaggccaccc tgcagcacga ggccaccgtg
     3661 gccacgctgc ggaagaagca cgcggacagc gcggcggagc tggcagagca gatcgacaac
     3721 ctgcagcgcg tcaagcagaa gctggagaag gagaagagcg agttcaagct ggagatcgac
     3781 gacctctcca gcagtgtgga gagtgtgtcc aaatccaagg ccaacctgga gaagatatgc
     3841 cgaactctag aggatcagtt aagcgaggcc aggggcaaga acgaggagac gcagagaagc
     3901 ctaagtgagc tgaccacaca gaagtcccgg ctgcagacag aagcgggtga gctgagtcgt
     3961 caactggaag aaaaggaaag catagtatct cagctttcca ggagcaagca agcctttacc
     4021 caacagatag aggagctcaa gaggcaactg gaggaagaga acaaggccaa gaatgcgctg
     4081 gcccacgccc tgcagtcctc ccgccacgac tgtgacctgc ttcgggaaca gtacgaggag
     4141 gagcaggaag gcaaagccga gctgcagagg gcgctgtcca aggccaacag cgaggtggcc
     4201 caatggagga ccaaatatga gacggatgcc atccagcgca cggaggagct ggaggaggcc
     4261 aaaaaaaagc ttgctcagcg ccttcaggat tcggaggagc aggtcgaggc tgtgaatgca
     4321 aaatgcgctt ccttggaaaa gaccaagcag aggctgcaag gggaggtgga ggacttgatg
     4381 gtggatgtgg agagagccaa ctctctggct gccgctctgg acaagaagca gaggaacttt
     4441 gacaaggtgt tagccgagtg gaagacgaag tgtgaggaga gccaagcaga gctggaggcg
     4501 gctctcaagg aatcccggtc cttgagcact gagctcttca aactgaaaaa cgcctatgaa
     4561 gaagccttgg atcaactcga aactgtgaag cgagagaata agaacttaga acaagagata
     4621 gcagatctca ccgaacaaat tgctgagaac ggtaaaagca tccacgagct agagaaatcc
     4681 agaaagcaga tggagctgga gaaggctgat atccagatgg cgctggagga agcagaggca
     4741 gctctggagc acgaagaagc caagatcctc aggatccagc ttgaactgac gcaggtgaaa
     4801 tcagagatcg atagaaagat cgcagagaag gatgaagaga tcgagcagct gaagaggaac
     4861 taccagagga cagtggagac catgcagggc gccctggatg ctgaggtgcg cagcaggaat
     4921 gaggcgatcc ggctgaagaa gaagatggag ggcgacctca atgagattga gatccagctg
     4981 agccatgcca accgccaggc cgcagagacc atcaagcacc tccggagtgt ccagggacag
     5041 ctgaaggaca cccagctgca cctggatgac gctctccgag gccaggagga cctgaaggag
     5101 cagctggcga tcgtggagcg cagagccaac ctgctgcagg ctgaggtgga ggagctgcgg
     5161 gccactctgg agcagacgga gagggcccgg aagctggcag agcaggagct gctggactcc
     5221 aacgagaggg ttcagctgct gcacacccag aacaccagcc tcatccacac caagaagaag
     5281 ttggagactg acctcacaca gctccagagt gaggtggagg atgccagcag ggacgcaagg
     5341 aacgccgagg agaaggccaa aaaggccatc actgatgccg ccatgatggc ggaggagcta
     5401 aagaaggagc aggacaccag cgcccatctg gagcggatga agaagaacct ggagcagacg
     5461 gtgaaggacc tgcagcaccg tctggacgag gctgagcagc tggcactgaa gggcggcaag
     5521 aagcagatcc agaaactgga gacgaggatc agagagctag agtttgagct ggaaggggaa
     5581 cagaagagga acacagagtc tgtgaagggc ctgaggaagt atgagcggcg tgtcaaggag
     5641 ctcacctacc agagtgagga ggacaggaag aatgtgctga gattgcagga tctggtggat
     5701 aaacttcaag tgaaagtcaa gtcctacaag aggcaggctg aggaggctga tgaacaagcc
     5761 aatgttcatc tcaccaagtt ccggaaagcc cagcatgagc tagaggaggc cgaggaacgt
     5821 gcggatattg cagaatcgca agtcaataaa ctgcgggcta aaacccggga cttcacctct
     5881 agccggatgg tggtccatga aagtgaggag tgagcatgtc ctcctggtga ggggcagaag
     5941 atatgcagaa tgtatgtttt cgtggctcct gaccatcctg cttaatttcc acgtaacccc
     6001 tttccacatg caataaaatt tgccttgttt caagt
//
