LOCUS       NM_001100690            6443 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus myosin heavy chain 14 (Myh14), mRNA.
ACCESSION   NM_001100690 XM_001080622 XM_218617
VERSION     NM_001100690.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6443)
  AUTHORS   Billington,N., Wang,A., Mao,J., Adelstein,R.S. and Sellers,J.R.
  TITLE     Characterization of three full-length human nonmuscle myosin II
            paralogs
  JOURNAL   J Biol Chem 288 (46), 33398-33410 (2013)
   PUBMED   24072716
REFERENCE   2  (bases 1 to 6443)
  AUTHORS   Revenu,C., Ubelmann,F., Hurbain,I., El-Marjou,F., Dingli,F.,
            Loew,D., Delacour,D., Gilet,J., Brot-Laroche,E., Rivero,F.,
            Louvard,D. and Robine,S.
  TITLE     A new role for the architecture of microvillar actin bundles in
            apical retention of membrane proteins
  JOURNAL   Mol Biol Cell 23 (2), 324-336 (2012)
   PUBMED   22114352
REFERENCE   3  (bases 1 to 6443)
  AUTHORS   Choi,B.O., Kang,S.H., Hyun,Y.S., Kanwal,S., Park,S.W., Koo,H.,
            Kim,S.B., Choi,Y.C., Yoo,J.H., Kim,J.W., Park,K.D., Choi,K.G.,
            Kim,S.J., Zuchner,S. and Chung,K.W.
  TITLE     A complex phenotype of peripheral neuropathy, myopathy, hoarseness,
            and hearing loss is linked to an autosomal dominant mutation in
            MYH14
  JOURNAL   Hum Mutat 32 (6), 669-677 (2011)
   PUBMED   21480433
REFERENCE   4  (bases 1 to 6443)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   5  (bases 1 to 6443)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   6  (bases 1 to 6443)
  AUTHORS   Kim,K.Y., Kovacs,M., Kawamoto,S., Sellers,J.R. and Adelstein,R.S.
  TITLE     Disease-associated mutations and alternative splicing alter the
            enzymatic and motile activity of nonmuscle myosins II-B and II-C
  JOURNAL   J Biol Chem 280 (24), 22769-22775 (2005)
   PUBMED   15845534
REFERENCE   7  (bases 1 to 6443)
  AUTHORS   Turney,S.G. and Bridgman,P.C.
  TITLE     Laminin stimulates and guides axonal outgrowth via growth cone
            myosin II activity
  JOURNAL   Nat Neurosci 8 (6), 717-719 (2005)
   PUBMED   15880105
REFERENCE   8  (bases 1 to 6443)
  AUTHORS   Bao,J., Jana,S.S. and Adelstein,R.S.
  TITLE     Vertebrate nonmuscle myosin II isoforms rescue small interfering
            RNA-induced defects in COS-7 cell cytokinesis
  JOURNAL   J Biol Chem 280 (20), 19594-19599 (2005)
   PUBMED   15774463
  REMARK    Erratum:[J Biol Chem. 2006 Apr 14;281(15):10652]
REFERENCE   9  (bases 1 to 6443)
  AUTHORS   Donaudy,F., Snoeckx,R., Pfister,M., Zenner,H.P., Blin,N., Di
            Stazio,M., Ferrara,A., Lanzara,C., Ficarella,R., Declau,F.,
            Pusch,C.M., Nurnberg,P., Melchionda,S., Zelante,L., Ballana,E.,
            Estivill,X., Van Camp,G., Gasparini,P. and Savoia,A.
  TITLE     Nonmuscle myosin heavy-chain gene MYH14 is expressed in cochlea and
            mutated in patients affected by autosomal dominant hearing
            impairment (DFNA4)
  JOURNAL   Am J Hum Genet 74 (4), 770-776 (2004)
   PUBMED   15015131
REFERENCE   10 (bases 1 to 6443)
  AUTHORS   Golomb,E., Ma,X., Jana,S.S., Preston,Y.A., Kawamoto,S.,
            Shoham,N.G., Goldin,E., Conti,M.A., Sellers,J.R. and Adelstein,R.S.
  TITLE     Identification and characterization of nonmuscle myosin II-C, a new
            member of the myosin II family
  JOURNAL   J Biol Chem 279 (4), 2800-2808 (2004)
   PUBMED   14594953
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On or before Dec 12, 2007 this sequence version replaced
            XM_218617.4, XM_001080622.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643299.2273.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760386,
                                           SAMEA5760393 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-38                JAXUCZ010000001.1  104295307-104295344 c
            39-434              JAXUCZ010000001.1  104289705-104290100 c
            435-591             JAXUCZ010000001.1  104284583-104284739 c
            592-619             JAXUCZ010000001.1  104282021-104282048 c
            620-722             JAXUCZ010000001.1  104281725-104281827 c
            723-746             JAXUCZ010000001.1  104281185-104281208 c
            747-839             JAXUCZ010000001.1  104279177-104279269 c
            840-903             JAXUCZ010000001.1  104278794-104278857 c
            904-1002            JAXUCZ010000001.1  104277494-104277592 c
            1003-1143           JAXUCZ010000001.1  104276344-104276484 c
            1144-1239           JAXUCZ010000001.1  104269048-104269143 c
            1240-1358           JAXUCZ010000001.1  104266200-104266318 c
            1359-1511           JAXUCZ010000001.1  104264350-104264502 c
            1512-1685           JAXUCZ010000001.1  104264084-104264257 c
            1686-1859           JAXUCZ010000001.1  104263419-104263592 c
            1860-1974           JAXUCZ010000001.1  104262885-104262999 c
            1975-2162           JAXUCZ010000001.1  104258734-104258921 c
            2163-2284           JAXUCZ010000001.1  104257865-104257986 c
            2285-2354           JAXUCZ010000001.1  104257345-104257414 c
            2355-2515           JAXUCZ010000001.1  104256789-104256949 c
            2516-2624           JAXUCZ010000001.1  104256018-104256126 c
            2625-2756           JAXUCZ010000001.1  104255157-104255288 c
            2757-2963           JAXUCZ010000001.1  104254399-104254605 c
            2964-3101           JAXUCZ010000001.1  104253811-104253948 c
            3102-3225           JAXUCZ010000001.1  104253374-104253497 c
            3226-3397           JAXUCZ010000001.1  104253051-104253222 c
            3398-3610           JAXUCZ010000001.1  104251920-104252132 c
            3611-3755           JAXUCZ010000001.1  104250259-104250403 c
            3756-3962           JAXUCZ010000001.1  104249888-104250094 c
            3963-4067           JAXUCZ010000001.1  104249228-104249332 c
            4068-4220           JAXUCZ010000001.1  104248994-104249146 c
            4221-4469           JAXUCZ010000001.1  104247889-104248137 c
            4470-4682           JAXUCZ010000001.1  104246686-104246898 c
            4683-4895           JAXUCZ010000001.1  104242891-104243103 c
            4896-5057           JAXUCZ010000001.1  104242094-104242255 c
            5058-5186           JAXUCZ010000001.1  104241139-104241267 c
            5187-5275           JAXUCZ010000001.1  104240531-104240619 c
            5276-5399           JAXUCZ010000001.1  104240317-104240440 c
            5400-5608           JAXUCZ010000001.1  104238455-104238663 c
            5609-5717           JAXUCZ010000001.1  104235388-104235496 c
            5718-5890           JAXUCZ010000001.1  104233615-104233787 c
            5891-6443           JAXUCZ010000001.1  104232778-104233330 c
FEATURES             Location/Qualifiers
     source          1..6443
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..6443
                     /gene="Myh14"
                     /note="myosin heavy chain 14"
                     /db_xref="GeneID:308572"
                     /db_xref="RGD:1306821"
     exon            1..38
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            39..434
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     CDS             42..6044
                     /gene="Myh14"
                     /EC_number="5.6.1.8"
                     /note="myosin, heavy polypeptide 14; myosin, heavy chain
                     14, non-muscle"
                     /codon_start=1
                     /product="myosin-14"
                     /protein_id="NP_001094160.1"
                     /db_xref="GeneID:308572"
                     /db_xref="RGD:1306821"
                     /translation="MATVTLSVPGRKVASRPGPVPEAAQPFLFAPRTPNVGGPGGPQV
                     EWTARRMVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK
                     AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRG
                     KKRHEVPPHIYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSP
                     KGRKEPGVPASVSTMSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDI
                     AGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPYSHYRFL
                     TNGPSSSPGQERELFQETLESLRVLGLLPEEITAMLRTVSAVLQFGNIVLKKERNTDQ
                     ATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKA
                     TYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQ
                     LFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPK
                     ATDKSFVEKVAQEQGSHPKFQRPRNLRDQADFSVLHYAGKVDYKANEWLMKNMDPLND
                     NVAALLHQSTDRLTAEIWKDVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESL
                     SRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRI
                     LFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQ
                     LEEERDLKVTDIIVSFQAAARGYLARRAFQRRQQQQSALRVMQRNCAAYLKLRNWQWW
                     RLFIKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLA
                     EQLRAEAELCSEAEETRARLAARKQELELVVTELEARVGEEEECSRQLQSEKKRLQQH
                     IQELETHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERRLLEERLA
                     EFSSQAAEEEEKVKSLNKLRVKYEATIADMEDRLKKEEKGRQELEKLKRRLDGESSEL
                     QEQMMEQKQRAEELLIQLGRKEEELQSALVRAEEEGGARAQLLKSLREAQAGLAEAQE
                     DLEAERVARAKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTL
                     EEEARTHEVAMQELRQRHSQALVELTEQLEQARRGKSVWEKTRLSLEAEVSELKTELS
                     SLQTSRQEGEQKRRRLESQLQEVQGRSSDSERARAEAAEKLQRAQVELESVSTALSEA
                     ESKAIRLSKELSSAESQLHDTQELLQEETRAKLALGSRVRALEAEAAGLREQMEEEVV
                     ARERAGRELQTTQAQLSEWRRRQEEEAAVLEAGEEARRRAAREAETLAQRLAEKTEAV
                     ERLERARRRLQQELDDATVDLGQQKQLLSTLEKKQRKFDQLLAEEKAAVLRAVEDRER
                     VEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKNVHELE
                     RARRVAEQAASDLRTQVTELEDELTAAEDAKLRLEVTVQALKAQHERDLQGRDDAGEE
                     RRRQLAKQLRDAEVERDEERKQRALAMAARKKLELELEELKAQTSAAGQGKEEAVKQL
                     KKMQAQMKELWREVEETRSSREEMFTLSRESEKRLKGLEAEVLRLQEELAASDRARRQ
                     AQQDRDEMAEEVASGNLSKAATLEEKRQLEGRLGQLEEELEEEQNNSELLKDHYRKLV
                     LQVETLTTELSAERSFSAKAESGRQQLERQIQELRARLGEEDAGARARQKMLIAALES
                     KLAQAEEQLEQESRERILSGKLVRRAEKRLKEVVLQVDEERRVADQLRDQLEKSNLRL
                     KQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTT
                     RTVRQVFRLEEGVASDEEEAEGAEPGSAPTQEPEAPPPAAPQ"
     exon            435..591
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            592..619
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            620..722
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            723..746
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            747..839
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            840..903
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            904..1002
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            1003..1143
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            1144..1239
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            1240..1358
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            1359..1511
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            1512..1685
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            1686..1859
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            1860..1974
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            1975..2162
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            2163..2284
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            2285..2354
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            2355..2515
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            2516..2624
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            2625..2756
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            2757..2963
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            2964..3101
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            3102..3225
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            3226..3397
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            3398..3610
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            3611..3755
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            3756..3962
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            3963..4067
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            4068..4220
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            4221..4469
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            4470..4682
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            4683..4895
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            4896..5057
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            5058..5186
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            5187..5275
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            5276..5399
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            5400..5608
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            5609..5717
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            5718..5890
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
     exon            5891..6443
                     /gene="Myh14"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgtccaggc cgaggcctct ggaccgccct gggcgccgac catggccaca gtgaccttgt
       61 ccgtgcctgg gaggaaggtg gcctccaggc caggcccggt gcctgaggca gcccagccat
      121 tcctgttcgc gccccggacg ccaaatgtag gtggccctgg agggccacag gtggagtgga
      181 cagcacggcg catggtgtgg gtgccctcgg aactgcatgg gttcgaggca gcagccctgc
      241 gggatgaagg ggaggaggag gcagaagtgg agctggcgga gagtgggcgg cgcctgcggc
      301 tgcccaggga ccagatccag cgcatgaacc cacccaagtt cagcaaggca gaagatatgg
      361 ctgagctcac ctgcctcaac gaggcctcgg tcctgcacaa tctgcgagag cgctactact
      421 ctgggctcat ttatacctac tctggcctct tctgtgtggt cattaacccg tacaagcagc
      481 tgcctatcta cacggaggcc attgttgaaa tgtaccgggg caagaagcgc cacgaggtgc
      541 cacctcacat ctatgccgtg accgagggcg cgtaccgcag catgcttcag gatcgtgagg
      601 atcagtccat tctctgcacg ggagagtctg gagctgggaa gacggagaac accaagaagg
      661 tcatccagta cctggcccat gtggcatcat ctccaaaggg caggaaggaa cctggtgtcc
      721 ctgcctccgt cagcaccatg tcttatgggg agctagagcg gcagcttctt caagccaacc
      781 ccatcctaga agccttcggc aatgccaaaa cggtgaagaa cgacaactct tcccgatttg
      841 gcaaattcat ccgcatcaac tttgatattg ctggctacat cgtgggagca aacatcgaga
      901 cctatctgct ggagaagtcc cgggccatca gacaggccaa ggacgaatgc agcttccata
      961 tcttctacca gctgctaggg ggcgctgggg agcagctaaa agctgacctc cttctggagc
     1021 cctactccca ttaccgcttc ctgaccaacg ggccctcatc atcccccggc caggagcggg
     1081 agttattcca ggagaccctg gagtccctgc gagtgctggg cctcctccca gaagagatca
     1141 ctgccatgct gcgcacagtc tcagctgtcc tccagtttgg caacattgtc ctgaagaaag
     1201 agcggaacac ggatcaagcc accatgcctg acaacacagc tgcccagaag ctttgccgcc
     1261 tcttgggact tggagtgact gacttctcca gagcccttct cacgccccgc atcaaagtcg
     1321 gccgagatta cgtccagaaa gcacagacca aagagcaggc tgactttgcg ctggaggctc
     1381 tggccaaagc tacctatgag cgcctgttcc gctggctggt tctgcggctc aaccgtgccc
     1441 tggacagaag cccacgtcag ggcgcctcct tcctgggcat cctggacatc gcaggctttg
     1501 agatcttcca gctgaactcc ttcgagcagc tgtgcatcaa ctacaccaat gagaagctgc
     1561 agcagctgtt caaccacacc atgttcgtgc tggagcagga ggagtaccag cgagaaggca
     1621 tcccctggac cttcctggac tttgggttgg acctgcagcc ttgtatcgac ctcattgagc
     1681 ggccggccaa ccctccaggt ctcctggccc tgctggacga ggagtgctgg ttccccaagg
     1741 ccactgacaa gtcttttgtg gagaaggttg cccaggagca gggcagccac cccaagttcc
     1801 agcgtcctag gaacctacga gatcaagcgg acttcagcgt cctgcactac gcaggcaagg
     1861 ttgactacaa agccaatgag tggttgatga agaacatgga tccattgaat gacaatgtgg
     1921 ccgccttgct tcaccagagc acagatcgtc tcacagctga gatctggaag gatgtggagg
     1981 gcatcgtggg gctggagcaa gtgagcagcc ttggagatgg ccccccggga ggccgccccc
     2041 gccgtggaat gttccggacc gtggggcagc tctacaaaga atccctgagc cgcctcatgg
     2101 ccacgctcag caacaccaac cctagttttg tccgctgcat cgttcccaat catgagaaga
     2161 gggctgggaa actggagccg cgcctggtgc tggaccagct ccgttgtaat ggtgtcctcg
     2221 agggtatccg catctgtcgc caaggtttcc ccaaccgcat cctctttcag gagttccggc
     2281 agcgctatga aatcctcacc ccgaacgcca ttcccaaggg cttcatggac ggcaaacagg
     2341 cctgtgagaa gatgatccag gccctggagc tagaccccaa cttgtaccgt gttggccaaa
     2401 gcaagatctt cttccgggca ggggtcctag ctcaactgga ggaggagcga gatctcaagg
     2461 tcaccgacat catagtatct tttcaggcag cggcacgggg ctacctggcc cgtagggctt
     2521 tccagaggag gcagcagcag cagagtgctc tgagggtgat gcagagaaac tgtgccgcct
     2581 acctcaagct gaggaactgg cagtggtgga gactgttcat caaggtgaag cccctgctgc
     2641 aggtgacacg gcaggatgag gtgctgcagg cgcgagccca ggagctacag aaagttcagg
     2701 agctgcagca gcagagcgcc cgtgaagtgg gggaactgca gggtcgagtg gcacagctag
     2761 aggaggagcg tgcgcgcctg gctgagcagc tgcgagcgga agcggagctg tgctctgagg
     2821 cggaggagac acgggcacga ttggctgccc ggaagcagga gctggagctg gtggtgacag
     2881 agctggaggc acgagtgggc gaggaagaag agtgcagccg gcagctacag agcgagaaga
     2941 agaggctgca gcagcacatc caggagctgg agacccacct agaagcagag gagggtgccc
     3001 ggcagaaact gcagctggag aaagtgacca cagaggccaa gatgaagaag tttgaggagg
     3061 atctgctgct cctggaagac cagaattcca agctgagcaa ggagcggagg ctgctggagg
     3121 agcgcctggc tgagttctcc tcacaggcag cagaagagga agagaaagtc aaaagcctta
     3181 acaagctgag ggtcaaatat gaagccacaa tcgcagacat ggaagaccga ctgaagaaag
     3241 aggagaaagg ccgccaggaa ctagagaagc tgaagcgacg gctggatggg gagagctcag
     3301 agcttcagga acagatgatg gagcagaagc agagggcaga ggagctgctc atacagctgg
     3361 gccgcaagga ggaagagctg cagtcggccc tggtcagggc agaggaggag ggtggtgccc
     3421 gtgctcagct gctcaagtct ctgcgagagg cacaggctgg ccttgctgag gcccaggagg
     3481 acctggaagc tgagcgggta gccagggcca aggcggagaa gcagcgccgg gacctgggcg
     3541 aggagttgga ggcgctccgc ggggagctag aggacacgct ggattccacc aacgcccagc
     3601 aggagctgcg gtccaagagg gagcaggagg tgacagagct gaaaaagact ttggaagagg
     3661 aggcccggac tcacgaggtg gccatgcagg agctgagaca gaggcatagc caggccctgg
     3721 tggagctgac agagcagttg gagcaagcac ggaggggcaa aagtgtgtgg gagaagaccc
     3781 ggctctccct ggaggctgag gtgtctgaac ttaagacgga gctgagcagc ctgcagacct
     3841 caagacagga gggtgagcag aagaggcgac gcctggagtc ccagctacag gaggtccagg
     3901 gccgatccag cgattccgag agggctcggg ctgaggctgc tgagaagcta cagagagccc
     3961 aggtggaact tgagagcgtg tccacagccc taagtgaggc tgagtccaag gccatcaggc
     4021 tgagcaagga gctgagcagt gcagagtccc agctgcacga cacccaggaa ctgctgcagg
     4081 aggagaccag ggcaaagctg gctttggggt cccgtgtgcg tgccctggag gccgaggcag
     4141 ccgggcttcg ggagcagatg gaagaggagg tggttgccag ggaacgggct ggccgagagc
     4201 tgcagaccac acaggcccag ctctctgaat ggcggcgacg ccaggaagaa gaggctgccg
     4261 tgctggaggc tggggaggag gctcggcgcc gtgcagcccg ggaggcagag accctggccc
     4321 agcgcctggc agaaaagact gaggctgtag aaagactgga gcgagcccgg cggcggctgc
     4381 agcaggagct ggacgacgcc actgtggacc tggggcagca gaaacagctc ctgagcacac
     4441 tggagaagaa gcagcgaaag tttgaccagc tcctggcaga ggagaaggct gcagtgctac
     4501 gggctgtgga agatcgtgaa cgggtagagg ctgaaggccg ggagcgagag gcccgggccc
     4561 tgtcgctgac acgggccctg gaagaggagc aggaggcacg ggaggagctg gagaggcaga
     4621 accgtgctct gcgggctgag ctggaggcac tgctaagcag caaggatgat gttggcaaga
     4681 atgtgcacga gctcgagcga gcccgcaggg tggctgaaca ggcagccagt gacctgcgga
     4741 cacaggtgac agaactggag gatgagctga ctgccgcgga ggatgccaaa ctgcgcctgg
     4801 aggtgactgt gcaggccctg aaggctcaac atgaacgcga cctgcagggc cgtgatgatg
     4861 ctggcgagga gaggcggagg cagctggcca agcagctgag agacgcagag gtagagcgcg
     4921 atgaggaacg gaagcagagg gcactggcca tggctgcccg caagaagctg gagttggaac
     4981 tggaggagtt gaaggcacag acatctgctg ctgggcaggg caaggaagag gcagtgaagc
     5041 agctgaagaa gatgcaggcc cagatgaagg agctgtggcg ggaggtggag gagacgcgta
     5101 gctcccgcga ggagatgttt accctgagca gggaaagtga gaagaggctc aaggggttgg
     5161 aagctgaggt gctgcggctg caggaggaac tggctgcctc agaccgagcc cggaggcagg
     5221 cacagcagga cagagatgag atggcagagg aggtggccag tggcaacctt agcaaggcag
     5281 ccaccctgga ggagaaacgg cagctggagg ggcgactggg ccagttggaa gaggagctgg
     5341 aggaagagca gaataactcg gagctgctca aggaccacta ccgaaagctg gtgctacagg
     5401 tagagaccct caccacagag ctgtctgctg aacgcagttt ctcagccaag gctgagagtg
     5461 gaaggcagca gctggagcgg cagatccagg aactgcgggc ccgcctgggt gaagaggatg
     5521 ctggagccag agccaggcag aaaatgctga tcgccgctct tgagtctaaa ctggcccagg
     5581 cagaggagca gctggagcag gagagcagag agcgcatcct ctctggcaag ctggtacgca
     5641 gagccgagaa gcggctgaag gaggtggttc ttcaggtgga tgaagagcgc agggtggctg
     5701 accagctccg ggaccagctg gagaaaagca acctccggct gaagcagctc aagagacagc
     5761 tggaggaggc agaggaggaa gcatctcggg cacaggctgg ccggaggcgt ctgcagcggg
     5821 agctggagga cgtcactgag tctgcagaat ccatgaaccg ggaggtgacc acgctgagga
     5881 acaggctccg gcgtggcccg cttactttca ccacgcgaac tgtgcgccag gtgttccggc
     5941 tggaagaggg cgtggcttcc gacgaggaag aggctgaggg ggcagagcct ggttctgcac
     6001 caacccagga gcctgaggct ccgccccctg ccgctcccca gtgatccagt ctgtccgaga
     6061 tgccccaagg acagagccct ttctggtgtc cctcctggtt tgcactttga aatgacactg
     6121 tcctctggca ctttctggca tcgatgaacc ctactgggac cccaggaccc ctgctcactg
     6181 gggactccaa atcaaggccc caaaccaagg agctgggtgg gagggaggca aggatggtcg
     6241 ctcatgttag agaaacaaaa ttgaacatgg atgtcaagga tgtccagtct gctcctgttt
     6301 tcagcaggcc tgtcccctgg agaggacagg agggtgcttc caccccctgt cttgctctct
     6361 ttggggggag gggtgctcat aggatagcgc tcatggtccc tcatgctcca gacactaaag
     6421 aaataaactg gctggaccct tca
//
