LOCUS       NM_001005545            1207 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Rattus norvegicus MYG1 exonuclease (Myg1), mRNA.
ACCESSION   NM_001005545 XM_217056
VERSION     NM_001005545.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1207)
  AUTHORS   Philips,M.A., Kingo,K., Karelson,M., Ratsep,R., Aunin,E.,
            Reimann,E., Reemann,P., Porosaar,O., Vikesa,J., Nielsen,F.C.,
            Vasar,E., Silm,H. and Koks,S.
  TITLE     Promoter polymorphism -119C/G in MYG1 (C12orf10) gene is related to
            vitiligo susceptibility and Arg4Gln affects mitochondrial entrance
            of Myg1
  JOURNAL   BMC Med Genet 11, 56 (2010)
   PUBMED   20377893
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1207)
  AUTHORS   Philips,M.A., Abramov,U., Lillevali,K., Luuk,H., Kurrikoff,K.,
            Raud,S., Plaas,M., Innos,J., Puussaar,T., Koks,S. and Vasar,E.
  TITLE     Myg1-deficient mice display alterations in stress-induced responses
            and reduction of sex-dependent behavioural differences
  JOURNAL   Behav Brain Res 207 (1), 182-195 (2010)
   PUBMED   19818808
REFERENCE   3  (bases 1 to 1207)
  AUTHORS   Philips,M.A., Vikesa,J., Luuk,H., Jonson,L., Lillevali,K.,
            Rehfeld,J.F., Vasar,E., Koks,S. and Nielsen,F.C.
  TITLE     Characterization of MYG1 gene and protein: subcellular distribution
            and function
  JOURNAL   Biol Cell 101 (6), 361-373 (2009)
   PUBMED   19014353
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC082112.1.
            
            On Oct 8, 2004 this sequence version replaced XM_217056.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC082112.1, FQ230067.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1207
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q36"
     gene            1..1207
                     /gene="Myg1"
                     /gene_synonym="C12orf10"
                     /note="MYG1 exonuclease"
                     /db_xref="GeneID:300258"
                     /db_xref="RGD:1359237"
     exon            1..217
                     /gene="Myg1"
                     /gene_synonym="C12orf10"
                     /inference="alignment:Splign:2.1.0"
     CDS             2..1147
                     /gene="Myg1"
                     /gene_synonym="C12orf10"
                     /note="UPF0160 protein MYG1, mitochondrial; melanocyte
                     proliferating gene 1"
                     /codon_start=1
                     /product="MYG1 exonuclease precursor"
                     /protein_id="NP_001005545.1"
                     /db_xref="GeneID:300258"
                     /db_xref="RGD:1359237"
                     /translation="MGRGFLRGVLTLLPLRSVLQVQHCMLVSEPDLPPKRPRNNLMAP
                     PRIGTHNGTFHCDEALACALLRLLPEYRNAEIVRTRDPEKLALCDIVVDVGGEYNPQR
                     HRYDHHQRTFTETMSSLCPGKPWQTKLSSAGLVYLHFGHKLLAQLLGTSEEDSVVDTI
                     YDKMYENFVEEVDAVDNGISQWAEGEPRYALTTTLSARVSRLNPTWNQPDQDTEAGFR
                     RAMDLVQEEFLQRLNFYQHSWLPARALVEEALAQRFKVDSSGEIVELAKGGCPWKEHL
                     YHLESELSPTVAITFVIYTDQAGQWRVQCVPKEPHSFQSRLPLPEPWRGLRDEALDQV
                     SGIPGCIFVHASGFIGGHHTREGALNMARATLAQRTAPVPLANAVVQ"
     exon            218..330
                     /gene="Myg1"
                     /gene_synonym="C12orf10"
                     /inference="alignment:Splign:2.1.0"
     exon            331..490
                     /gene="Myg1"
                     /gene_synonym="C12orf10"
                     /inference="alignment:Splign:2.1.0"
     exon            491..643
                     /gene="Myg1"
                     /gene_synonym="C12orf10"
                     /inference="alignment:Splign:2.1.0"
     exon            644..766
                     /gene="Myg1"
                     /gene_synonym="C12orf10"
                     /inference="alignment:Splign:2.1.0"
     exon            767..948
                     /gene="Myg1"
                     /gene_synonym="C12orf10"
                     /inference="alignment:Splign:2.1.0"
     exon            949..1163
                     /gene="Myg1"
                     /gene_synonym="C12orf10"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tatgggtaga gggttcctgc gaggagtctt aacactgttg ccgctccggt cagttctcca
       61 agtccagcac tgcatgcttg tctcggagcc cgatctgccc cctaaaagac ctcgcaacaa
      121 cctcatggca ccgccccgaa tcgggacgca caacggcacc ttccactgcg atgaggctct
      181 ggcttgcgca ttgctccgcc tactgcccga gtacaggaat gcagagattg tgcggactcg
      241 ggatcctgaa aaactggctt tgtgtgacat cgtggtggat gtgggtggtg agtacaaccc
      301 tcagagacac cgttatgatc atcaccagag gacttttaca gaaaccatga gttccttgtg
      361 ccctgggaag ccatggcaga ccaagttgag cagtgcggga cttgtctatc tgcactttgg
      421 gcataagctc ctggcccagt tgctgggcac tagtgaagag gacagcgtgg tggacaccat
      481 ctatgacaag atgtacgaga actttgtgga agaggtggat gctgtggaca atgggatctc
      541 tcagtgggca gagggggagc ctcgctatgc actgaccact acactgagtg cccgggtttc
      601 tcgccttaat cccacctgga accagcctga ccaagacact gaggcaggat tcaggcgtgc
      661 gatggacctg gtgcaagagg agtttctgca aagactaaac ttctaccagc acagctggct
      721 gccagcccgg gccttggtag aggaggccct ggcccagaga ttcaaggtag actcaagtgg
      781 ggagatagtg gaacttgcaa agggcggatg cccttggaag gagcatctgt accacctaga
      841 atctgagctg tctcccacag tagccatcac ctttgttatc tacactgacc aggctggaca
      901 gtggcgagtc cagtgtgtgc ccaaggagcc tcactcattc caaagccggc tgcccctgcc
      961 cgagccatgg cggggacttc gggatgaggc cctggaccaa gtcagtggga tccctggttg
     1021 catcttcgtc catgccagtg gcttcattgg tgggcaccac actcgagagg gtgccctgaa
     1081 catggcccgt gccacccttg cccagcgcac agcacctgta cctcttgcaa atgctgtagt
     1141 ccaataaaac ttattcatct ctaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1201 aaaaaaa
//
