LOCUS       NP_001005545             381 aa            linear   ROD 01-JUN-2024
DEFINITION  MYG1 exonuclease precursor [Rattus norvegicus].
ACCESSION   NP_001005545 XP_217056
VERSION     NP_001005545.1
DBSOURCE    REFSEQ: accession NM_001005545.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 381)
  AUTHORS   Philips,M.A., Kingo,K., Karelson,M., Ratsep,R., Aunin,E.,
            Reimann,E., Reemann,P., Porosaar,O., Vikesa,J., Nielsen,F.C.,
            Vasar,E., Silm,H. and Koks,S.
  TITLE     Promoter polymorphism -119C/G in MYG1 (C12orf10) gene is related to
            vitiligo susceptibility and Arg4Gln affects mitochondrial entrance
            of Myg1
  JOURNAL   BMC Med Genet 11, 56 (2010)
   PUBMED   20377893
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 381)
  AUTHORS   Philips,M.A., Abramov,U., Lillevali,K., Luuk,H., Kurrikoff,K.,
            Raud,S., Plaas,M., Innos,J., Puussaar,T., Koks,S. and Vasar,E.
  TITLE     Myg1-deficient mice display alterations in stress-induced responses
            and reduction of sex-dependent behavioural differences
  JOURNAL   Behav Brain Res 207 (1), 182-195 (2010)
   PUBMED   19818808
REFERENCE   3  (residues 1 to 381)
  AUTHORS   Philips,M.A., Vikesa,J., Luuk,H., Jonson,L., Lillevali,K.,
            Rehfeld,J.F., Vasar,E., Koks,S. and Nielsen,F.C.
  TITLE     Characterization of MYG1 gene and protein: subcellular distribution
            and function
  JOURNAL   Biol Cell 101 (6), 361-373 (2009)
   PUBMED   19014353
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC082112.1.
            
            On Oct 8, 2004 this sequence version replaced XP_217056.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC082112.1, FQ230067.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q36"
     Protein         1..381
                     /product="MYG1 exonuclease precursor"
                     /note="UPF0160 protein MYG1, mitochondrial; melanocyte
                     proliferating gene 1"
                     /calculated_mol_wt=37589
     transit_peptide 1..47
                     /note="Mitochondrion. /evidence=ECO:0000255; propagated
                     from UniProtKB/Swiss-Prot (Q641W2.1)"
                     /calculated_mol_wt=5318
     Region          46..366
                     /region_name="UPF0160"
                     /note="Uncharacterized protein family (UPF0160);
                     pfam03690"
                     /db_xref="CDD:461014"
     mat_peptide     48..381
                     /product="MYG1 exonuclease. /id=PRO_0000371227"
                     /note="propagated from UniProtKB/Swiss-Prot (Q641W2.1)"
                     /calculated_mol_wt=37589
     Site            267
                     /site_type="acetylation"
                     /note="N6-acetyllysine.
                     /evidence=ECO:0000250|UniProtKB:Q9HB07; propagated from
                     UniProtKB/Swiss-Prot (Q641W2.1)"
     Site            273
                     /site_type="acetylation"
                     /note="N6-acetyllysine.
                     /evidence=ECO:0000250|UniProtKB:Q9JK81; propagated from
                     UniProtKB/Swiss-Prot (Q641W2.1)"
     CDS             1..381
                     /gene="Myg1"
                     /gene_synonym="C12orf10"
                     /coded_by="NM_001005545.1:2..1147"
                     /db_xref="GeneID:300258"
                     /db_xref="RGD:1359237"
ORIGIN      
        1 mgrgflrgvl tllplrsvlq vqhcmlvsep dlppkrprnn lmapprigth ngtfhcdeal
       61 acallrllpe yrnaeivrtr dpeklalcdi vvdvggeynp qrhrydhhqr tftetmsslc
      121 pgkpwqtkls saglvylhfg hkllaqllgt seedsvvdti ydkmyenfve evdavdngis
      181 qwaegeprya ltttlsarvs rlnptwnqpd qdteagfrra mdlvqeeflq rlnfyqhswl
      241 paralveeal aqrfkvdssg eivelakggc pwkehlyhle selsptvait fviytdqagq
      301 wrvqcvpkep hsfqsrlplp epwrglrdea ldqvsgipgc ifvhasgfig ghhtregaln
      361 maratlaqrt apvplanavv q
//
