LOCUS       NM_001013205            2945 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus myelin expression factor 2 (Myef2), mRNA.
ACCESSION   NM_001013205 XM_001054154 XM_001081059
VERSION     NM_001013205.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2945)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   2  (bases 1 to 2945)
  AUTHORS   Haas,S., Steplewski,A., Siracusa,L.D., Amini,S. and Khalili,K.
  TITLE     Identification of a sequence-specific single-stranded DNA binding
            protein that suppresses transcription of the mouse myelin basic
            protein gene
  JOURNAL   J Biol Chem 270 (21), 12503-12510 (1995)
   PUBMED   7539003
REFERENCE   3  (bases 1 to 2945)
  AUTHORS   McDermott,J.C., Cardoso,M.C., Yu,Y.T., Andres,V., Leifer,D.,
            Krainc,D., Lipton,S.A. and Nadal-Ginard,B.
  TITLE     hMEF2C gene encodes skeletal muscle- and brain-specific
            transcription factors
  JOURNAL   Mol Cell Biol 13 (4), 2564-2577 (1993)
   PUBMED   8455629
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Feb 28, 2022 this sequence version replaced NM_001013205.2.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760389
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, expression,
                                         longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-212               JAXUCZ010000003.1  132827312-132827523 c
            213-421             JAXUCZ010000003.1  132820665-132820873 c
            422-474             JAXUCZ010000003.1  132819416-132819468 c
            475-482             JAXUCZ010000003.1  132818015-132818022 c
            483-576             JAXUCZ010000003.1  132817820-132817913 c
            577-768             JAXUCZ010000003.1  132813824-132814015 c
            769-922             JAXUCZ010000003.1  132813016-132813169 c
            923-972             JAXUCZ010000003.1  132812547-132812596 c
            973-1036            JAXUCZ010000003.1  132812363-132812426 c
            1037-1138           JAXUCZ010000003.1  132803493-132803594 c
            1139-1189           JAXUCZ010000003.1  132802030-132802080 c
            1190-1258           JAXUCZ010000003.1  132801683-132801751 c
            1259-1357           JAXUCZ010000003.1  132801284-132801382 c
            1358-1429           JAXUCZ010000003.1  132800936-132801007 c
            1430-1638           JAXUCZ010000003.1  132799287-132799495 c
            1639-1690           JAXUCZ010000003.1  132799088-132799139 c
            1691-2945           JAXUCZ010000003.1  132791694-132792948 c
FEATURES             Location/Qualifiers
     source          1..2945
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q36"
     gene            1..2945
                     /gene="Myef2"
                     /note="myelin expression factor 2"
                     /db_xref="GeneID:679712"
                     /db_xref="RGD:1306547"
     exon            1..212
                     /gene="Myef2"
                     /inference="alignment:Splign:2.1.0"
     CDS             79..1854
                     /gene="Myef2"
                     /note="myelin basic protein expression factor 2,
                     repressor"
                     /codon_start=1
                     /product="myelin expression factor 2"
                     /protein_id="NP_001013223.2"
                     /db_xref="GeneID:679712"
                     /db_xref="RGD:1306547"
                     /translation="MADADKPEAAAGDDGPQQQPAEPRRDPHPGEPEKPPRSSANGVK
                     MENDESVKEEKSDLKEKSTGNKKANRFHPYSKDKNSGTGEKKGPNRNRVFISNIPYDM
                     KWQAIKDLMREKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGR
                     PLNIKEDPDGENARRALQRTGTSFQGSHASDVGSGLVNLPPSIVNNPNIPPEVINNLQ
                     AGRLGSTIFVANLDFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIE
                     AVQAISMFNGQFLFDRPMHVKMDDKSVPHEDYRSHDSKTSQLPRGLGGIGMGLGPGGQ
                     PISASQLNITGVMGNLGPSGMGMDGPGFGGVNRIGGGVGFGGLEAMNSMAGFGGVGRM
                     GELYRGAMTSSMERDFGRGDIGLSRGFGDSFGRLGSAMIGGFAGRIGASNMGPVGTGI
                     SGSMSGMSTVTGGMGMGLDRMSSSFDRMGPGIGAILERSIDVDRGFLSGPMGSGMRDR
                     LGSKGNQIFVRNLPFDLTWQKLKEKFSQCGHVMFAEIKMENGKSKGCGTVRFESPESA
                     EKACRIMNGIKISGREIDVRLDRNA"
     exon            213..421
                     /gene="Myef2"
                     /inference="alignment:Splign:2.1.0"
     exon            422..474
                     /gene="Myef2"
                     /inference="alignment:Splign:2.1.0"
     exon            475..482
                     /gene="Myef2"
                     /inference="alignment:Splign:2.1.0"
     exon            483..576
                     /gene="Myef2"
                     /inference="alignment:Splign:2.1.0"
     exon            577..768
                     /gene="Myef2"
                     /inference="alignment:Splign:2.1.0"
     exon            769..922
                     /gene="Myef2"
                     /inference="alignment:Splign:2.1.0"
     exon            923..972
                     /gene="Myef2"
                     /inference="alignment:Splign:2.1.0"
     exon            973..1036
                     /gene="Myef2"
                     /inference="alignment:Splign:2.1.0"
     exon            1037..1138
                     /gene="Myef2"
                     /inference="alignment:Splign:2.1.0"
     exon            1139..1189
                     /gene="Myef2"
                     /inference="alignment:Splign:2.1.0"
     exon            1190..1258
                     /gene="Myef2"
                     /inference="alignment:Splign:2.1.0"
     exon            1259..1357
                     /gene="Myef2"
                     /inference="alignment:Splign:2.1.0"
     exon            1358..1429
                     /gene="Myef2"
                     /inference="alignment:Splign:2.1.0"
     exon            1430..1638
                     /gene="Myef2"
                     /inference="alignment:Splign:2.1.0"
     exon            1639..1690
                     /gene="Myef2"
                     /inference="alignment:Splign:2.1.0"
     exon            1691..2945
                     /gene="Myef2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atccgttacc gctccgccgg ccgtcgccat tgtagcgctc ggagccctaa gcgcggccga
       61 ggcggagccc gcggcgggat ggccgatgcc gacaagcccg aggcggccgc gggtgacgac
      121 ggcccgcagc agcaaccggc tgagccgcgg cgagacccgc accccggcga gccggagaaa
      181 ccgccgcgca gcagcgccaa cggcgttaaa atggagaatg atgaatcagt gaaggaagaa
      241 aaatctgatt taaaagaaaa gtctacagga aataagaagg ccaatcggtt tcatccttat
      301 tcaaaagata agaattcggg cactggagaa aagaaaggtc caaatcggaa cagagtgttc
      361 attagcaaca tcccctatga catgaaatgg caggctatta aagatttgat gagagaaaaa
      421 gttggtgagg ttacatacgt ggagctcttt aaggatgcgg aaggaaaatc aaggggttgt
      481 ggcgtggttg aattcaaaga tgaagaattt gtaaagaaag cattagaaac tatgaacaaa
      541 tatgacctta gtggaagacc tctgaatatt aaagaggatc ccgatggaga aaatgctcgc
      601 cgtgcactgc agcgaacagg aacatcattt caaggatcac atgcctctga tgtaggatct
      661 gggctggtga atttaccacc ttccattgtg aataatccaa acattcctcc tgaggttatc
      721 aacaacttgc aggctggtag acttggttcc acaatttttg ttgctaatct tgacttcaaa
      781 gttggttgga aaaaactaaa ggaagtgttc agcatagctg gaactgtgaa gcgagctgat
      841 attaaagaag acaaggacgg caagagcaga ggcatgggca cggtcacttt tgagcaggca
      901 atcgaagcag tccaagcaat ttccatgttc aatgggcagt ttttatttga tagacctatg
      961 catgtgaaaa tggatgacaa atctgtccct catgaagact accgttcaca tgatagtaag
     1021 acatcacaat taccacgtgg tcttggaggc attggaatgg gactgggtcc aggtggacag
     1081 ccaattagtg ccagccagct gaacataact ggtgtaatgg gaaatttagg tccaagtggt
     1141 atgggaatgg atggtccggg ttttggagga gtgaatagaa ttggaggagg cgttgggttt
     1201 ggtggtctgg aagcaatgaa tagcatggca ggctttggtg gagttggccg aatgggagag
     1261 ttgtaccgcg gtgcaatgac tagtagcatg gagcgagatt tcggacgtgg tgatattgga
     1321 ttgagtcgag gctttggcga ctcctttggt agacttggca gtgcaatgat tggagggttt
     1381 gcaggaagaa taggagcttc taacatgggt ccagtaggaa ctggaataag tggcagcatg
     1441 agcggcatga gcaccgtgac gggaggcatg ggaatgggcc tggaccgcat gagctccagc
     1501 ttcgacagga tggggccagg catcggagcc atactggaaa ggagcattga cgtggaccga
     1561 gggtttttat cgggtcccat gggaagtgga atgagagaca gattaggctc caagggcaac
     1621 cagatatttg ttagaaatct tccttttgac ttgacttggc agaaattaaa agagaaattc
     1681 agccaatgtg gtcatgtaat gtttgcagaa ataaagatgg agaatggcaa gtcaaaaggc
     1741 tgtgggacag tcaggtttga atccccagag tcagctgaaa aggcctgcag aataatgaac
     1801 ggcatcaaga tcagtggcag ggaaatcgat gtgcgcttgg accgtaatgc ataatttcaa
     1861 gcatggttgg aacattccct catctgttta ttgactccta gtaaaagtca ttttttagta
     1921 atgttgtatg cttacaaatg ctgtaaaaaa tgaactttta aaactcccac cagcttttaa
     1981 cagtataatg ttgaaaaaca tactgtgatt ttcgttctct caagtttgag tttctagaaa
     2041 cagcacgtct gatcattcag tttcaatgga tggacatacc atttgtaatg aaataagcca
     2101 ttttgttatt ttcagtagta gagtttgttt gttctagttt ctccaacatt attttaagtt
     2161 aacagatact tttttttttc ttttaaaatc tctgctttgt atttaattgt taaagaaagg
     2221 gctcagacaa attagggtgt gattttggtt tggtttaaat tacttttctc tgcttataaa
     2281 ggatagtaat taagtgttac actctaaagt tgaagatttt ttttttaatt tgacctaaat
     2341 gaagacatga atttttttgc ccctctatca ttccagttgt tccacataac attattaaaa
     2401 atatcaaatt ccacagcccc ttactctgtt atttccaatg attccaagtt catatagtac
     2461 tgataaagta gcaagtccta agtatgacac taggcagacc acccccaact ttcggtctag
     2521 tttccagccg ttaaaatgaa ccgctaagaa cagaagaaag attgaaatgt tgagagagat
     2581 ggttatataa gtgagtccct tgctgttcac ttctatagga gcagatgcat tcgtaaatgc
     2641 agtcttaata aaccagggaa gaccaaggca tagcatatca aacacattgg atcccacgat
     2701 gttagatata gccatgtctc ctttacctgc agaagaatag catgttgtta aaatgtgcac
     2761 atcaacacta tattttatta ataatcttca taagaaaaac actggatact tttgttggtt
     2821 agttttagaa aactgttgtt agagcaagag tcttattgaa tttgtatttc cttgggttag
     2881 tattttaaag tcttaacatt tatttaataa ttgtctttat ttattaaacc atttttaata
     2941 aggta
//
