LOCUS       NM_001399360            2744 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus myeloid-derived growth factor (Mydgf), mRNA.
ACCESSION   NM_001399360 XM_039084328
VERSION     NM_001399360.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2744)
  AUTHORS   Gualberto Cavalcanti,N., MeloVilar,K., Branco Pinto Duarte,A.L.,
            Jesus Barreto de Melo Rego,M., Cristiny Pereira,M., da Rocha
            Pitta,I., Diniz Lopes Marques,C. and Galdino da Rocha Pitta,M.
  TITLE     IL-27 in patients with Chikungunya fever: A possible chronicity
            biomarker?
  JOURNAL   Acta Trop 196, 48-51 (2019)
   PUBMED   31075222
REFERENCE   2  (bases 1 to 2744)
  AUTHORS   Urazova,O.I., Churina,E.G., Hasanova,R.R., Novitskiy,V.V. and
            Poletika,V.S.
  TITLE     Association between polymorphisms of cytokine genes and secretion
            of IL-12p70, IL-18, and IL-27 by dendritic cells in patients with
            pulmonary tuberculosis
  JOURNAL   Tuberculosis (Edinb) 115, 56-62 (2019)
   PUBMED   30948177
REFERENCE   3  (bases 1 to 2744)
  AUTHORS   Bortnov,V., Annis,D.S., Fogerty,F.J., Barretto,K.T., Turton,K.B.
            and Mosher,D.F.
  TITLE     Myeloid-derived growth factor is a resident endoplasmic reticulum
            protein
  JOURNAL   J Biol Chem 293 (34), 13166-13175 (2018)
   PUBMED   29954947
REFERENCE   4  (bases 1 to 2744)
  AUTHORS   Chairakaki,A.D., Saridaki,M.I., Pyrillou,K., Mouratis,M.A.,
            Koltsida,O., Walton,R.P., Bartlett,N.W., Stavropoulos,A., Boon,L.,
            Rovina,N., Papadopoulos,N.G., Johnston,S.L. and Andreakos,E.
  TITLE     Plasmacytoid dendritic cells drive acute asthma exacerbations
  JOURNAL   J Allergy Clin Immunol 142 (2), 542-556 (2018)
   PUBMED   29054692
REFERENCE   5  (bases 1 to 2744)
  AUTHORS   Aladegbami,B., Barron,L., Bao,J., Colasanti,J., Erwin,C.R.,
            Warner,B.W. and Guo,J.
  TITLE     Epithelial cell specific Raptor is required for initiation of type
            2 mucosal immunity in small intestine
  JOURNAL   Sci Rep 7 (1), 5580 (2017)
   PUBMED   28717211
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2744)
  AUTHORS   Zhu,C., Zhang,R., Liu,L., Rasool,S.T., Mu,Y., Sun,W., Hao,Q.,
            Liu,F., Zhu,Y. and Wu,J.
  TITLE     Hepatitis B virus enhances interleukin-27 expression both in vivo
            and in vitro
  JOURNAL   Clin Immunol 131 (1), 92-97 (2009)
   PUBMED   19081304
REFERENCE   7  (bases 1 to 2744)
  AUTHORS   Mchenga,S.S., Wang,D., Li,C., Shan,F. and Lu,C.
  TITLE     Inhibitory effect of recombinant IL-25 on the development of
            dextran sulfate sodium-induced experimental colitis in mice
  JOURNAL   Cell Mol Immunol 5 (6), 425-431 (2008)
   PUBMED   19118508
REFERENCE   8  (bases 1 to 2744)
  AUTHORS   Owyang,A.M., Zaph,C., Wilson,E.H., Guild,K.J., McClanahan,T.,
            Miller,H.R., Cua,D.J., Goldschmidt,M., Hunter,C.A., Kastelein,R.A.
            and Artis,D.
  TITLE     Interleukin 25 regulates type 2 cytokine-dependent immunity and
            limits chronic inflammation in the gastrointestinal tract
  JOURNAL   J Exp Med 203 (4), 843-849 (2006)
   PUBMED   16606667
REFERENCE   9  (bases 1 to 2744)
  AUTHORS   Wang,P., Mariman,E., Keijer,J., Bouwman,F., Noben,J.P., Robben,J.
            and Renes,J.
  TITLE     Profiling of the secreted proteins during 3T3-L1 adipocyte
            differentiation leads to the identification of novel adipokines
  JOURNAL   Cell Mol Life Sci 61 (18), 2405-2417 (2004)
   PUBMED   15378209
REFERENCE   10 (bases 1 to 2744)
  AUTHORS   Larousserie,F., Pflanz,S., Coulomb-L'Hermine,A., Brousse,N.,
            Kastelein,R. and Devergne,O.
  TITLE     Expression of IL-27 in human Th1-associated granulomatous diseases
  JOURNAL   J Pathol 202 (2), 164-171 (2004)
   PUBMED   14743498
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On Jan 6, 2022 this sequence version replaced XM_039084328.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643297.30667.1,
                                           SRR26643285.33556.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760476,
                                           SAMN12840108 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-172               JAXUCZ010000009.1  1095797-1095968     c
            173-223             JAXUCZ010000009.1  1094703-1094753     c
            224-285             JAXUCZ010000009.1  1091129-1091190     c
            286-367             JAXUCZ010000009.1  1090337-1090418     c
            368-440             JAXUCZ010000009.1  1089811-1089883     c
            441-2744            JAXUCZ010000009.1  1086825-1089128     c
FEATURES             Location/Qualifiers
     source          1..2744
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q11"
     gene            1..2744
                     /gene="Mydgf"
                     /note="myeloid-derived growth factor"
                     /db_xref="GeneID:501282"
                     /db_xref="RGD:1589603"
     exon            1..172
                     /gene="Mydgf"
                     /inference="alignment:Splign:2.1.0"
     CDS             20..520
                     /gene="Mydgf"
                     /codon_start=1
                     /product="myeloid-derived growth factor precursor"
                     /protein_id="NP_001386289.1"
                     /db_xref="GeneID:501282"
                     /db_xref="RGD:1589603"
                     /translation="MAAPSSGFWTALVLAAAALKLAAAVSEPTTVPFDVRPGGVVHSF
                     SQDIGPGGKFTCTFTYASQGGTNEQWQMSLGTSEDSQHFTCTVWRPQGKSYLYFTQFK
                     AELQGAEIEYAMAYSKAAFERESDVPLKSEEFEVTKTAVSHRPGAFKAELSKLVIVAK
                     AAHSEL"
     exon            173..223
                     /gene="Mydgf"
                     /inference="alignment:Splign:2.1.0"
     exon            224..285
                     /gene="Mydgf"
                     /inference="alignment:Splign:2.1.0"
     exon            286..367
                     /gene="Mydgf"
                     /inference="alignment:Splign:2.1.0"
     exon            368..440
                     /gene="Mydgf"
                     /inference="alignment:Splign:2.1.0"
     exon            441..2744
                     /gene="Mydgf"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcattgcccc ggaagcaaga tggcggcccc cagcagtggc ttctggactg cgctggttct
       61 ggcggccgcg gcgctaaagt tggcggccgc tgtgtctgag cccaccaccg tgccatttga
      121 cgtgaggccc ggaggtgtcg tgcattcctt ctcccaggac ataggacccg ggggcaagtt
      181 tacatgcaca ttcacttacg cttcccaagg agggaccaac gagcagtggc agatgagcct
      241 gggcacaagc gaagacagtc agcactttac ctgtaccgtc tggaggcccc aggggaaatc
      301 ctacctctac ttcacacagt tcaaggctga gttgcagggt gctgagatcg agtacgccat
      361 ggcctactcc aaagctgcat ttgagagaga gagtgatgtc cccctgaaaa gcgaggagtt
      421 tgaagtgacc aagacagcag tgtctcacag gcctggggcc ttcaaagctg agctctccaa
      481 gctggtgata gtagccaagg cggcacactc ggagctgtga ccctcacctg tcatgagcct
      541 tcacgtcctc tttcctgagg cacactggcc tggactgctt gtctagggca ctggttcctt
      601 tgggagctgg cattgccctg tacaggtgac actgtgtcac tcttcagaac tctctgagcc
      661 ccgtcgccca tctcaccagg gaaggtgcag gacatgtgcg ggtaggatgg aaggacatcc
      721 tggctttcct aaggcaagac gtggtgtggt ttctcctctg agccctccca gcaccacttc
      781 ctaaccccac acagggcacc tccactcaga aggatgggaa aagatagaac aaataaataa
      841 ataagtaacc accttagcag aggctctctg gggtgaggac tccggcatga cttctcacca
      901 tcttccacag tagcatagca ggtgcaggca cgtggcctct cctaatgact ggcacatagg
      961 tgctagcaca gtgggtccca aggcagccag tgactttgca ccctcaagga tgggtcactc
     1021 tcctgagaca ccatgttgcc ttgaatccac actgtgttct cgatctagca ggacaaagcc
     1081 aatgtcccca cagattctgg cttcaggtgg gtttttaaag tcggatggaa gcaacatgta
     1141 tttagatttt tcttatgctg tgtctgtgtg gtggtggggg ggtgagaagg ggaggaggag
     1201 tttgagttag tgagtgctgt gaatttgtgc tatttgtgtg ctcatggaaa taagaagagg
     1261 gcattgcatc tcctggccct agagttacaa gtggttgtga actgtctgtg ggtgctggga
     1321 attgaacttc agtcctctgc aaaagcagcc agtgctttta acagcttagc cacctttata
     1381 gccctataag aaaaaataaa acaggggttg gggattcagc tcagtggtag agcgcttgcc
     1441 tagcaaatgc aaggccctgg gttcagtccc cagctctgaa aaaaaaaaaa taataaaaaa
     1501 aaaaataaag caaaggcctg gagagatggc tcagtggtta agagcactga ttgctcttgc
     1561 caaggacctg agttcaattc cctgcaacct catcgcggct cacaaccata tgtaatgcca
     1621 atgccctctt ctggtgtgtc tgaaaatagc aacagtgtac tcatataaat aaaaaaatct
     1681 ttaaaaaaaa aatctagcaa aacacctgaa gccaaggaac cctaaagttc ctaaagtggc
     1741 cttaaagtgt ccaagccttt cagacggacc ttggggccct ccagctacac ctttgggcct
     1801 gacatctcac tggacatcca gtgaggcact gggactacca gacaggtctg taccttacaa
     1861 ggatctgcag gggtgctgca ccttttcaca taacgtttgt gcgtgcatgt atgtgtgtgt
     1921 gtgtgtgtgt gtgtgtgtga tcccacagca agagccaagt accctttttg ttccccgttc
     1981 agccattagg taaaggcaaa ggcatcgctg tgagttggag gctagcctgg actacataca
     2041 gagttccagg actacataat gggactatac cacaagaaag ggaatctggc cattaagaca
     2101 agaggatatt tcacatagct tatacccttg gaaggacaac catcagtggt gccttagggg
     2161 cctgaggttc cagggactct gaaacatgga tttaggccca agccctcaag ctcctacgta
     2221 agaaagagca cagcacggat gaagtgaggc caggctatgt ggctgctcct gtgtgccttt
     2281 cagagtctcc agttattact caggatacag agtaggtaga actgagtgcc aggacatatt
     2341 agccctttaa tgtgtttctg ggcgggaaac gttgggaatg aaccaagcac tttaagtatg
     2401 ggagggcagt gatgctgcag agccacaccc agatcctcag atcatcttac tgaaggccac
     2461 agccaccggc ctgtgatact gacctaaaga gatggagtgg gacctggtgg gggagccaac
     2521 ccccatcctg ttatccctgg gctgggcaga tcaatcttgg ctgtgggtgc ttgagagcca
     2581 tggaacatag gacgacatgt gggacttgac tctccttcct ttctgtggta cccaggatca
     2641 gatagactta ggtcaccagg ctgggagtgg agtaccttgg tggcagagcc tctgtagtgt
     2701 tcatgaggcc caatgacaca aagtaataaa gtgtgctccc ggtg
//
