LOCUS       NP_068609                430 aa            linear   ROD 30-MAR-2024
DEFINITION  protein S-Myc [Rattus norvegicus].
ACCESSION   NP_068609
VERSION     NP_068609.2
DBSOURCE    REFSEQ: accession NM_021837.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 430)
  AUTHORS   Watson,J.D., Oster,S.K., Shago,M., Khosravi,F. and Penn,L.Z.
  TITLE     Identifying genes regulated in a Myc-dependent manner
  JOURNAL   J Biol Chem 277 (40), 36921-36930 (2002)
   PUBMED   12145275
  REMARK    GeneRIF: genes are idenetified that are regulated by Myc genes
REFERENCE   2  (residues 1 to 430)
  AUTHORS   Szpirer,C., Szpirer,J., Van Vooren,P., Tissir,F., Simon,J.S.,
            Koike,G., Jacob,H.J., Lander,E.S., Helou,K., Klinga-Levan,K. and
            Levan,G.
  TITLE     Gene-based anchoring of the rat genetic linkage and cytogenetic
            maps: new regional localizations, orientation of the linkage
            groups, and insights into mammalian chromosome evolution
  JOURNAL   Mamm Genome 9 (9), 721-734 (1998)
   PUBMED   9716657
REFERENCE   3  (residues 1 to 430)
  AUTHORS   Sugiyama,A., Kume,A., Nemoto,K., Lee,S.Y., Asami,Y., Nemoto,F.,
            Nishimura,S. and Kuchino,Y.
  TITLE     Isolation and characterization of s-myc, a member of the rat myc
            gene family
  JOURNAL   Proc Natl Acad Sci U S A 86 (23), 9144-9148 (1989)
   PUBMED   2594755
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000021.1.
            
            On Dec 7, 2020 this sequence version replaced NP_068609.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: SRR26643293.32382.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq12"
     Protein         1..430
                     /product="protein S-Myc"
                     /calculated_mol_wt=46928
     Region          10..331
                     /region_name="Myc_N"
                     /note="Myc amino-terminal region; pfam01056"
                     /db_xref="CDD:460045"
     Site            36
                     /site_type="phosphorylation"
                     /note="Phosphotyrosine, by Tyr-kinases.
                     /evidence=ECO:0000250; propagated from
                     UniProtKB/Swiss-Prot (P23999.1)"
     Region          302..326
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (P23999.1)"
     Region          344..430
                     /region_name="bHLHzip_N-Myc_like"
                     /note="basic Helix-Loop-Helix-zipper (bHLHzip) domain
                     found in N-Myc and similar proteins; cd11456"
                     /db_xref="CDD:381462"
     Site            order(344,348..349,352..353,355..357,359..360,364,
                     384..385)
                     /site_type="other"
                     /note="putative DNA binding site [nucleotide binding]"
                     /db_xref="CDD:381462"
     Site            order(363,366..367,369..370,373,386,389..390,393,395..397,
                     399..400,402..403,406,409..410,413..414,416..418,420..421,
                     423..430)
                     /site_type="other"
                     /note="putative tetramer interface [polypeptide binding]"
                     /db_xref="CDD:381462"
     Site            order(363,366..367,369..370,373,386,389..390,393,395..397,
                     399..400,402..403,406,409..410,413..414,416..417,420,
                     423..424,427..428,430)
                     /site_type="other"
                     /note="putative dimer interface [polypeptide binding]"
                     /db_xref="CDD:381462"
     Region          399..420
                     /region_name="Leucine-zipper"
                     /note="propagated from UniProtKB/Swiss-Prot (P23999.1)"
     CDS             1..430
                     /gene="Mycs"
                     /coded_by="NM_021837.2:1..1293"
                     /db_xref="GeneID:24581"
                     /db_xref="RGD:3133"
ORIGIN      
        1 mlscttstmp gmicknsdle fdslkpcfyp edddiyfggr nstppgediw kkfellptpr
       61 lspgralaed slepanwate mllpeadlws npaeeedifg lkglsgsssn pvvlqdcmws
      121 gfssrekpet vvseklpggc gslavgagtl vpgaaaaass agharsgtag vgrrkaawlt
      181 elshldsecv dsavifpank resmpvatip asagaaislg dhqglsssle dflsnsgyve
      241 eggeeiyvvm lgetqfsktv tklptaahse naaltpecaq sgelilkrsd liqeqhnyaa
      301 pplpyaedar plkkprsqdp lgplkcvlrp kaprlrsrsn sdledierrr nhnrmerqrr
      361 dimrssflnl rdlvpelvhn ekaakvvilk kateyihtlq tdeskllver eklyerkqql
      421 lekikqsavc
//
