LOCUS       NM_001106055           15421 bp    mRNA    linear   ROD 14-JAN-2025
DEFINITION  Rattus norvegicus MYC binding protein 2 (Mycbp2), mRNA.
ACCESSION   NM_001106055 XM_001076799 XM_214245
VERSION     NM_001106055.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 15421)
  AUTHORS   AlAbdi,L., Desbois,M., Rusnac,D.V., Sulaiman,R.A., Rosenfeld,J.A.,
            Lalani,S., Murdock,D.R., Burrage,L.C., Billie Au,P.Y., Towner,S.,
            Wilson,W.G., Wong,L., Brunet,T., Strobl-Wildemann,G., Burton,J.E.,
            Hoganson,G., McWalter,K., Begtrup,A., Zarate,Y.A.,
            Christensen,E.L., Opperman,K.J., Giles,A.C., Helaby,R., Kania,A.,
            Zheng,N., Grill,B. and Alkuraya,F.S.
  CONSRTM   Undiagnosed Diseases Network
  TITLE     Loss-of-function variants in MYCBP2 cause neurobehavioural
            phenotypes and corpus callosum defects
  JOURNAL   Brain 146 (4), 1373-1387 (2023)
   PUBMED   36200388
REFERENCE   2  (bases 1 to 15421)
  AUTHORS   Wang,G., Miao,C., Mo,L., Kahlert,U.D., Wu,J., Ou,M., Huang,R.,
            Feng,R., Pang,W. and Shi,W.
  TITLE     MYCBP2 expression correlated with inflammatory cell infiltration
            and prognosis immunotherapy in thyroid cancer patients
  JOURNAL   Front Immunol 13, 1048503 (2022)
   PUBMED   36582246
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 15421)
  AUTHORS   Liang,J., Zhou,W., Sakre,N., DeVecchio,J., Ferrandon,S., Ting,A.H.,
            Bao,S., Bissett,I., Church,J. and Kalady,M.F.
  TITLE     Epigenetically regulated miR-1247 functions as a novel tumour
            suppressor via MYCBP2 in methylator colon cancers
  JOURNAL   Br J Cancer 119 (10), 1267-1277 (2018)
   PUBMED   30318507
REFERENCE   4  (bases 1 to 15421)
  AUTHORS   Pao,K.C., Wood,N.T., Knebel,A., Rafie,K., Stanley,M., Mabbitt,P.D.,
            Sundaramoorthy,R., Hofmann,K., van Aalten,D.M.F. and Virdee,S.
  TITLE     Activity-based E3 ligase profiling uncovers an E3 ligase with
            esterification activity
  JOURNAL   Nature 556 (7701), 381-385 (2018)
   PUBMED   29643511
REFERENCE   5  (bases 1 to 15421)
  AUTHORS   Bento,C.F., Ashkenazi,A., Jimenez-Sanchez,M. and Rubinsztein,D.C.
  TITLE     The Parkinson's disease-associated genes ATP13A2 and SYT11 regulate
            autophagy via a common pathway
  JOURNAL   Nat Commun 7, 11803 (2016)
   PUBMED   27278822
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 15421)
  AUTHORS   Lewcock,J.W., Genoud,N., Lettieri,K. and Pfaff,S.L.
  TITLE     The ubiquitin ligase Phr1 regulates axon outgrowth through
            modulation of microtubule dynamics
  JOURNAL   Neuron 56 (4), 604-620 (2007)
   PUBMED   18031680
REFERENCE   7  (bases 1 to 15421)
  AUTHORS   Bloom,A.J., Miller,B.R., Sanes,J.R. and DiAntonio,A.
  TITLE     The requirement for Phr1 in CNS axon tract formation reveals the
            corticostriatal boundary as a choice point for cortical axons
  JOURNAL   Genes Dev 21 (20), 2593-2606 (2007)
   PUBMED   17901218
REFERENCE   8  (bases 1 to 15421)
  AUTHORS   Etournay,R., El-Amraoui,A., Bahloul,A., Blanchard,S., Roux,I.,
            Pezeron,G., Michalski,N., Daviet,L., Hardelin,J.P., Legrain,P. and
            Petit,C.
  TITLE     PHR1, an integral membrane protein of the inner ear sensory cells,
            directly interacts with myosin 1c and myosin VIIa
  JOURNAL   J Cell Sci 118 (Pt 13), 2891-2899 (2005)
   PUBMED   15976448
REFERENCE   9  (bases 1 to 15421)
  AUTHORS   Murthy,V., Han,S., Beauchamp,R.L., Smith,N., Haddad,L.A., Ito,N.
            and Ramesh,V.
  TITLE     Pam and its ortholog highwire interact with and may negatively
            regulate the TSC1.TSC2 complex
  JOURNAL   J Biol Chem 279 (2), 1351-1358 (2004)
   PUBMED   14559897
  REMARK    GeneRIF: Pam, through its interaction with tuberin, could regulate
            the ubiquitination and proteasomal degradation of the
            tuberin-hamartin complex particularly in the CNS [Mycbp2]
REFERENCE   10 (bases 1 to 15421)
  AUTHORS   Scholich,K., Pierre,S. and Patel,T.B.
  TITLE     Protein associated with Myc (PAM) is a potent inhibitor of adenylyl
            cyclases
  JOURNAL   J Biol Chem 276 (50), 47583-47589 (2001)
   PUBMED   11590159
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000015.1.
            
            On Oct 27, 2010 this sequence version replaced NM_001106055.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760386
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on computational evidence
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-650               JAXUCZ010000015.1  86589477-86590126   c
            651-726             JAXUCZ010000015.1  86563862-86563937   c
            727-942             JAXUCZ010000015.1  86554122-86554337   c
            943-1096            JAXUCZ010000015.1  86546984-86547137   c
            1097-1293           JAXUCZ010000015.1  86541764-86541960   c
            1294-1536           JAXUCZ010000015.1  86540154-86540396   c
            1537-1608           JAXUCZ010000015.1  86539873-86539944   c
            1609-1705           JAXUCZ010000015.1  86538192-86538288   c
            1706-1779           JAXUCZ010000015.1  86534227-86534300   c
            1780-1918           JAXUCZ010000015.1  86533121-86533259   c
            1919-1995           JAXUCZ010000015.1  86531680-86531756   c
            1996-2200           JAXUCZ010000015.1  86530735-86530939   c
            2201-2365           JAXUCZ010000015.1  86529422-86529586   c
            2366-2524           JAXUCZ010000015.1  86527058-86527216   c
            2525-2729           JAXUCZ010000015.1  86524406-86524610   c
            2730-2875           JAXUCZ010000015.1  86518512-86518657   c
            2876-2977           JAXUCZ010000015.1  86517920-86518021   c
            2978-3085           JAXUCZ010000015.1  86511362-86511469   c
            3086-3205           JAXUCZ010000015.1  86503976-86504095   c
            3206-3287           JAXUCZ010000015.1  86501326-86501407   c
            3288-3405           JAXUCZ010000015.1  86493923-86494040   c
            3406-3610           JAXUCZ010000015.1  86489675-86489879   c
            3611-3764           JAXUCZ010000015.1  86489085-86489238   c
            3765-3937           JAXUCZ010000015.1  86482322-86482494   c
            3938-4063           JAXUCZ010000015.1  86481576-86481701   c
            4064-4191           JAXUCZ010000015.1  86481367-86481494   c
            4192-4283           JAXUCZ010000015.1  86477947-86478038   c
            4284-4418           JAXUCZ010000015.1  86475625-86475759   c
            4419-4502           JAXUCZ010000015.1  86474026-86474109   c
            4503-4599           JAXUCZ010000015.1  86471999-86472095   c
            4600-4792           JAXUCZ010000015.1  86468420-86468612   c
            4793-5067           JAXUCZ010000015.1  86467971-86468245   c
            5068-5280           JAXUCZ010000015.1  86465234-86465446   c
            5281-5472           JAXUCZ010000015.1  86461112-86461303   c
            5473-5679           JAXUCZ010000015.1  86458917-86459123   c
            5680-5811           JAXUCZ010000015.1  86457734-86457865   c
            5812-5990           JAXUCZ010000015.1  86455772-86455950   c
            5991-6133           JAXUCZ010000015.1  86454045-86454187   c
            6134-6234           JAXUCZ010000015.1  86452437-86452537   c
            6235-6453           JAXUCZ010000015.1  86451606-86451824   c
            6454-6679           JAXUCZ010000015.1  86449009-86449234   c
            6680-6798           JAXUCZ010000015.1  86448094-86448212   c
            6799-6886           JAXUCZ010000015.1  86447448-86447535   c
            6887-6936           JAXUCZ010000015.1  86446323-86446372   c
            6937-7109           JAXUCZ010000015.1  86442391-86442563   c
            7110-7254           JAXUCZ010000015.1  86441327-86441471   c
            7255-7473           JAXUCZ010000015.1  86438680-86438898   c
            7474-7529           JAXUCZ010000015.1  86435831-86435886   c
            7530-7645           JAXUCZ010000015.1  86429874-86429989   c
            7646-7743           JAXUCZ010000015.1  86426992-86427089   c
            7744-7860           JAXUCZ010000015.1  86426206-86426322   c
            7861-8001           JAXUCZ010000015.1  86423608-86423748   c
            8002-8076           JAXUCZ010000015.1  86418420-86418494   c
            8077-8301           JAXUCZ010000015.1  86415929-86416153   c
            8302-8434           JAXUCZ010000015.1  86414964-86415096   c
            8435-8557           JAXUCZ010000015.1  86413725-86413847   c
            8558-8713           JAXUCZ010000015.1  86411058-86411213   c
            8714-10357          JAXUCZ010000015.1  86397268-86398911   c
            10358-10527         JAXUCZ010000015.1  86396006-86396175   c
            10528-10772         JAXUCZ010000015.1  86395210-86395454   c
            10773-10940         JAXUCZ010000015.1  86392959-86393126   c
            10941-11098         JAXUCZ010000015.1  86382976-86383133   c
            11099-11295         JAXUCZ010000015.1  86382096-86382292   c
            11296-11445         JAXUCZ010000015.1  86381177-86381326   c
            11446-11606         JAXUCZ010000015.1  86379620-86379780   c
            11607-11763         JAXUCZ010000015.1  86378497-86378653   c
            11764-11988         JAXUCZ010000015.1  86378101-86378325   c
            11989-12054         JAXUCZ010000015.1  86376142-86376207   c
            12055-12294         JAXUCZ010000015.1  86374615-86374854   c
            12295-12384         JAXUCZ010000015.1  86374098-86374187   c
            12385-12465         JAXUCZ010000015.1  86371972-86372052   c
            12466-12732         JAXUCZ010000015.1  86370472-86370738   c
            12733-13016         JAXUCZ010000015.1  86369729-86370012   c
            13017-13113         JAXUCZ010000015.1  86367191-86367287   c
            13114-13233         JAXUCZ010000015.1  86366385-86366504   c
            13234-13335         JAXUCZ010000015.1  86364779-86364880   c
            13336-13464         JAXUCZ010000015.1  86363978-86364106   c
            13465-13597         JAXUCZ010000015.1  86363530-86363662   c
            13598-13701         JAXUCZ010000015.1  86361989-86362092   c
            13702-13890         JAXUCZ010000015.1  86361421-86361609   c
            13891-13998         JAXUCZ010000015.1  86360653-86360760   c
            13999-14208         JAXUCZ010000015.1  86358944-86359153   c
            14209-14316         JAXUCZ010000015.1  86356800-86356907   c
            14317-14482         JAXUCZ010000015.1  86355585-86355750   c
            14483-15421         JAXUCZ010000015.1  86352061-86352999   c
FEATURES             Location/Qualifiers
     source          1..15421
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15q21"
     gene            1..15421
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /note="MYC binding protein 2"
                     /db_xref="GeneID:290447"
                     /db_xref="RGD:1312048"
     exon            1..650
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     CDS             349..14598
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /note="protein associated with Myc; pam, highwire, rpm 1;
                     probable E3 ubiquitin-protein ligase MYCBP2; probable E3
                     ubiquitin-protein ligase MYCBP2-like; MYC binding protein
                     2, E3 ubiquitin protein ligase"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase MYCBP2"
                     /protein_id="NP_001099525.2"
                     /db_xref="GeneID:290447"
                     /db_xref="RGD:1312048"
                     /translation="MMMCAATASPAAASSGPGGDGFFAAATISSSPAPGALFMPVPDG
                     SVAASGLGLGLPATDSRGQYQLLLSGRALADRYRRIYTTALSDRDQAGSSTGYPASRN
                     KKILNKKKLKRKQKSKSKVKTRSKSENLENTVIIPDIKLHSNPSAFNIYCNVRHCVLE
                     WQKKEASLAAASRNSVQSGESDSDEEEESRELPIKLPKIIEVGLCEVFELIKETRFSH
                     PSLCLRSLQALLNVLQGQQPEGLQSEPPEVLESLFQLLLEITVRSTGVNDSTGQSLTA
                     LSCACLFSLVASWGETGRTLQAISAILTNNGSHACQTIQVPTILNSLQRSVQAVLVGK
                     IQVQDWFSNGIKKAALMHKWPLKEISVDEDDQCLLQNDGFFLYLLCKDGLYKIGSGYS
                     GTVRGHIYNSTSRIRNRKEKKSWLGYAQGYLLYRDVNNHSMTAIRISPETLEQDGTVM
                     LPDCHTEGQNILFTDGEYINQIAASRDDGFVVRIFATSTEPVLQQELQLKLARKCLHA
                     CGISLFDLEKDLHIISTGFDEESAILGAGREFALMKTANGKIYYTGKYQSLGIKQGGP
                     SAGKWVELPITKSPKIVHFSVGHDGSHALLVAEDGSVFFTGSASKGEDGESAKSRRQS
                     KPYKPKKIIKMEGKIVVCTACNNGSSSVISKDGELYMFGKDAIYSDSSSLVSDLKGHF
                     VTQVAMGKAHTCVLMKNGEVWTFGVNNKGQCGRDTGAMNQGGKGFGVENMATAMDEDL
                     EEELDEKDEKSMMCPPGMHKWKLEQCMVCTVCGDCTGYGASCVSSGRPDRVPGGICGC
                     GSGESGCAVCGCCKACARELDGQEARQRGILDAVKEMIPLDLLLAVPVPGVNIEEHLQ
                     LRQEEKRQRVIRRHRLEDGRGPLVFAGPIFMNHREQALARLRSHPAQLKHKRDKHKDA
                     SGERGEKDASKVTTYPPGSVRFDCEVRAVQVSCGFHHSVVLMENGDVYTFGYGQHGQL
                     GHGDVNSRGCPTLVQALPGPSTQVTAGSNHTAVLVMDGQVFTFGSFSKGQLGRPILDV
                     PYWNAKPAPMPNIGSKYGRKATWIGASGDQTFLRIDEALINSHVLATSEIFASKHIIG
                     LVPASISEPPPFKCLLINKVDGSCKTFNDSEQEDLQGFGVCLDPVYDVLWRFRPSTRE
                     LWCYNAVVADARLPSATDMQSSCCILSPELALPTGSRALTTRSHAALHILGCLDTLAA
                     MQDLKMGIASIEEETQAVMKVYSKEDYSIVNRFESHGGGWGYSAHSVEAIRFSADTDI
                     LLGGLGLFGGRGEYTAKIKLFELGPDGGDHETDGDLLAETDVLAYDCAAREKYAMMFD
                     EPVLLQAGWWYVAWARVSGPSSDCGSHGQASITTDDGVIFQFKSSKKSNNGTDVNAGQ
                     IPQLLYRLPTCDGSTSKGKQQTSEPVHILKRSFARTVSVECFESLLSILHWSWTTLVL
                     GVEELRGLKGFQFTATLLDLERLRFVGTCCLRLLRVYTCEIYPVSAVGKAVVEETSKL
                     AECIGKTRTLLRKILSEGVDHCMVKLDNDPQGYLSQPLSLLESVLQECHNTFTACFHS
                     FYPTPALQWACLCDLLNCLDQEANFKTSSSRLLAAVMSALCHTSVKLTSLFPIAYDGE
                     VLLRSIVKQVSTENESTLVHRFPLLVGHMEKLSQSEENISGMTSFREVLEKMLVIVVL
                     PVRNSLRRESELFSSHLVSNTCGLLASIVSELTASALGSEVDGLNSLHSVKASANRFT
                     KTSQGRSWNTGNGSPDAICFAVDKPGIVVVGFSVYGGGGIHEYELEVLVDDSEHSGDS
                     THSHRWTSLELVKGTYTTDDSPSDIAEIRLDKVVPLKENVKYAVRLRNYGSRTANGDG
                     GMTTVQCPDGVTFTFSTCSLSSNGTNQTRGQIPQILYYRSEFDGDLQSQLVSKANEED
                     KNCSRALSVVSTVVRAAKDLLHRALAVDADDIPELLSSSSLFSMLLPLIIAYIGPVAA
                     AIPKVAVEVFGLVQQLLPSVAVLNQKYAPPAFNPNQSTDSTTGNQPEQGLSACTTSNH
                     YAVIESEHPYKPACVMHYKVTFPECVRWMTIEFDPQCGTAQSEDVLRLLTPVRTIQNA
                     GYGAKVTSAHENLNSWIELKKYSGSSGWPTMVLVLPGNEALFSLETASDYVKDDKASF
                     YGFKCFAIGYEFSPGPDEGVIQLEKELANLGGVCAAALMKKDLALPIGNELEEDLEIL
                     EEAALQVCKTHSGILGKGLALSHSPTILEALEGNLPLQIQSNEQSFLDDFIACVPGSS
                     GGRLARWLQPDSYADPQKTSLILNKDDIRCGWPTTITVQTKDQYGDVVHVPNMKVEVK
                     AVPVSQKKTSLQQEQVKKSQRVPGSPAAAAAASCTTDMTFGGLASPKLDVSYEPMIVK
                     EARYIAITMMKVYENYSFEELRFASPTPKRPSENMLIRVNNDGTYCANWTPGAIGLYT
                     VHVTIDGIEIDAGLEVKVKDPPKGMIPPGTQLVKPKADPQPNKIRKFVAKDSAGLRIR
                     SHPSLQSEQIGIVKVNGTITFIDEIHNDDGVWLRLNEETIRKYVPNMNGYTEAWCLSF
                     NQHLGKSLLVPVDNIFNASQGVRDLDVLSWTSKAFFPQEPKTTTDDFFKDVNTCCPQE
                     AAVRERDHPFLRGGPGMYKVVKTGPSGHNIRSCPNLRGIPIGMLVLGNKVKAVGEVTS
                     AEGTWVQLDKNSMVEFCESDEGEAWSLARDRGGNQYLRHEDEQVLLDQNSQTPPPSPF
                     SVQAFSKGASCSAQGFDYGLGNNKGDQLSAILNSIQSRPNLPAPSIFDQAAKPPSSLV
                     HSPFVFGQPLSFQQRQLQSDRGTVSTSSRPVSTSAKSELPSKNSRSVKPDGRVSRTTA
                     DQKKPRGTEGLSASESLMLKSDAAKLRSDSHSRSLSPNHNTLQTLKSDGRVSSSFRAE
                     SPGPGSRSSSPKPKTLPTPRSSPSGASSPRSSSPQDKNLPQKSTAPAKTKLDPPRERS
                     KSDSYTLDPDTLRKKKMPLTEPLRGRSTSPKPKPVPKDPKGSPGSENRAPSPHVVQEN
                     LHSEVVEVCTSSTLKTNGVTDSTCDDSNDFKSVDEGSNKVHFSIGKAPLKDEQEMRAS
                     PKISRKCANRHTRPKKEKSNFLFKGDGAKSLEPAKQAMSPSVAECARAVFASFLWHEG
                     IVHDAMACSSFLKFNPELSKEHAPIRSSLNSQPPTEEKEIKLKNRHSLEISSALNMFN
                     ISPHGPDISKMGSINKNKVLSMLKEPPLHEKCEDGKSEATFEMSMHHSVKSRSPLPLT
                     LQHLVAFWEDISLATIKAASQNMIFPSPGSCAVLKKKECEKENKKTKKEKKKKEKTEI
                     RPRGNLFGEMAQLAVGGPEKDTICELCGESHPYPVTYHMRQAHPGCGRYAGGQGYNSI
                     GHFCGGWAGNCGDGGMGGSTWYLVCDRCREKYLREKQAAAREKVKQSRRKPMQVKTPR
                     ALPTMEAHQVIKANALFLLSLSSAAEPSILCYHPAKPFQSQLPIVKEGVSEALPVKMP
                     CLYLQTLARHHHENFVGYQDDNLFQDEMRYLRSTSVPAPYISVTPDASPNVFEEPESN
                     MKSMPPSLETSPITDTDLAKRTVFQRSYSVVASEYDKQHSILPARVKAIPRRRVNSGD
                     TVGSSLLRHPSPELSRLISAHSSLSKGERNFQWPVLAFVIQHHDLEGLEIAMKQALRK
                     SACRVFAMEAFNWLLCNVIQTTSLHDILWHFVAALTPSPVEAEEDEDEDNKSSKENAE
                     QEKDTRVCEHPLSDIVIAGEAAHPLPHTFHRLLQTISDLMMSLPSGSSLQQMALRCWS
                     LKFKQSDHQFLHQSNVFHHINNILSKSDDGDSEESFSISIQSGFEAMNQELCIVMCLK
                     DLTSIVDIKTSSRPAMIGSLTDGSTETFWESGDEDKNKTKTITINCVKGINARYVSVH
                     VDNSRDLGNKVTSMTFLTGKAVEDLCRIKQVDLDSRHIGWVTSELPGGDNHIIKIELK
                     GPENTLRVRQVKVLGWKDGESTKIAGQISASVAQQRSCEAETLRVFRLITSQVFGKLI
                     SGDAEPTPEQEEKALLSSPEGEEKATSDADLKEHMVGIIFSRSKLTNLQKQVCAHIVQ
                     AIRMEATRVREEWEHAISSKENANSQPSDEDASSDAYCFELLSMVLALSGSNVGRQYL
                     AQQLTLLQDLCSLLHTASPRVQRQVTSLLRRVLPEVTPNRLASIIGVKSLPPADISDI
                     IHSTEKGDWNKLGILDMFLGCIAKALTVQLKAKGTTITGTAGTTVGKGVTTVTLPMIF
                     NSSYLRRGESHWWMKGSTPTQISEIIIKLIKDMAAGHLSEAWSRVTKNAIAETIIALT
                     KMEEEFRSPVRCIATTRLWLALASLCVLDQDHVDRLSSGRWMGKDGQQKQMPMCDNHD
                     DGETAAIILCNICGNLCTDCDRFLHLHRRTKTHQRQVFKEEEEAIKVDLHEGCGRTKL
                     FWLMALADSKTMKAMVEFREHTGKPTTSSSEACRFCGSRSGTELSAVGSVCSDADCQE
                     YAKIACSKTHPCGHPCGGVRNEEHCLPCLHGCDKNATTLKQDADDMCMICFTEALSAA
                     PAIQLDCSHVFHLQCCRRVLENRWLGPRITFGFISCPICKNKINHIVLKDLLDPIKEL
                     YEDVRRKALMRLEYEGLHKSEAITTPGVRFYNDPAGYAMNRYAYYVCYKCRKAYFGGE
                     ARCDAEAGQGDDYDPRELICGACSDVSRAQMCPKHGTDFLEYKCRYCCSVAVFFCFGT
                     THFCNACHDDFQRMTSIPKEELPHCPAGPKGKQLEGTECPLHVVHPPTGEEFALGCGV
                     CRNAHTF"
     exon            651..726
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            727..942
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            943..1096
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1097..1293
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1294..1536
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1537..1608
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1609..1705
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1706..1779
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1780..1918
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1919..1995
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1996..2200
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            2201..2365
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            2366..2524
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            2525..2729
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            2730..2875
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            2876..2977
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            2978..3085
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            3086..3205
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            3206..3287
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            3288..3405
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            3406..3610
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            3611..3764
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            3765..3937
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            3938..4063
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            4064..4191
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            4192..4283
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            4284..4418
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            4419..4502
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            4503..4599
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            4600..4792
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            4793..5067
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            5068..5280
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            5281..5472
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            5473..5679
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            5680..5811
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            5812..5990
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            5991..6133
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            6134..6234
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            6235..6453
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            6454..6679
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            6680..6798
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            6799..6886
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            6887..6936
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            6937..7109
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            7110..7254
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            7255..7473
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            7474..7529
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            7530..7645
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            7646..7743
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            7744..7860
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            7861..8001
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            8002..8076
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            8077..8301
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            8302..8434
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            8435..8557
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            8558..8713
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            8714..10357
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            10358..10527
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            10528..10772
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            10773..10940
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            10941..11098
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            11099..11295
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            11296..11445
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            11446..11606
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            11607..11763
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            11764..11988
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            11989..12054
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            12055..12294
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            12295..12384
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            12385..12465
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            12466..12732
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            12733..13016
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            13017..13113
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            13114..13233
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            13234..13335
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            13336..13464
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            13465..13597
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            13598..13701
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            13702..13890
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            13891..13998
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            13999..14208
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            14209..14316
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            14317..14482
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
     exon            14483..15421
                     /gene="Mycbp2"
                     /gene_synonym="Pam; Phr1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgtgcggag cggcgcgcat gctcagtgag gccggccgcc tcccattgcg ggcaactccg
       61 gcggtggcag cagcggcggc ggcggcggcg gcggcggcgg cggcggcggc accgcctcct
      121 cctcacactc cgcgggtggc ggggttagat gagtggcccc aacagcggcg agggcggcgt
      181 ggggaggagg aggagaaggc ggcggcggcg gagaaggtcg ctgtctttgt agtgtccctg
      241 ctgcgggcgc ccgaggccgc cgctacagcc gtcgtcgttg gccgagtctg tgagggcgcg
      301 cgcgtgcctg cccgcccggc ccgcggggac gaggcggcgg cggcgaggat gatgatgtgc
      361 gcggcgactg cctcccccgc cgccgcctcc tccgggcccg gcggggacgg cttctttgca
      421 gccgccacca tctcttcctc cccggcaccg ggggcgctgt tcatgccggt tcctgacggt
      481 tcggtggccg cttcgggact ggggctgggg ctgcctgcca cggactcccg gggtcagtat
      541 cagctgctgc tgtcaggccg ggccttggcg gatcgctacc ggaggattta caccactgcg
      601 ctcagtgaca gggaccaggc cggcagcagc actgggtacc cggcctccag gaataagaaa
      661 attttaaata agaagaaatt gaagcgaaaa cagaaaagca aatcaaaagt gaagacaaga
      721 agcaagtctg aaaacttgga gaatacagta attatccccg atatcaaact acatagcaat
      781 ccctcagcct tcaacattta ctgtaatgta cggcattgcg ttttggagtg gcagaaaaag
      841 gaagcatcac tggcagctgc atcgaggaac tctgtacaga gtggagaatc agacagtgat
      901 gaggaagagg agtccagaga gctccccatc aagcttccaa agattattga ggttgggctt
      961 tgtgaagtct ttgaattgat caaggagact cggttttctc atccatccct gtgtctaagg
     1021 agcctccaag ccctgctgaa tgtgcttcaa ggccagcagc cagaaggcct tcaatcagag
     1081 ccaccagagg tcctagagtc tctcttccag ctcctattgg agattacagt tcggagtact
     1141 ggggtgaatg acagcacagg gcagtccctc acagcactct cctgtgcttg cctctttagc
     1201 ctggtggcct cctggggaga aacaggaagg acacttcagg ccatctctgc tatcctaacc
     1261 aacaatggta gtcatgcttg ccaaacgatt caggtgccaa caatactaaa ttcactacag
     1321 agaagtgtac aggcagtgtt ggttggaaag attcaagtcc aggactggtt tagcaatggc
     1381 attaagaaag cagctttaat gcacaagtgg ccattaaagg aaatatctgt tgatgaagat
     1441 gaccagtgtc tgcttcagaa tgatggattt tttctttatt tgttatgcaa ggatggatta
     1501 tacaaaatag gctctggata cagtggaaca gttaggggtc atatatataa ttctacatct
     1561 cgtatcagaa acagaaaaga aaagaagtct tggttaggat atgcccaggg ttacttgtta
     1621 tatcgggatg tgaataacca cagtatgaca gccataagaa taagccccga aacgctggag
     1681 caagacggca ctgtaatgtt accagattgc cacactgaag gtcaaaatat tttatttact
     1741 gatggagagt atattaacca gatagctgct tcaagagatg atggctttgt tgtcaggata
     1801 tttgccacaa gcactgagcc tgtgctgcaa caagaactcc agctgaagct ggccaggaag
     1861 tgcttacatg cctgcggcat atctctgttt gatctggaga aggatttgca tataataagc
     1921 acagggtttg atgaagagtc agccatcctt ggtgcaggcc gagagtttgc gctaatgaaa
     1981 acagcgaatg gaaagattta ttacactggc aagtaccaga gtcttggaat caaacaaggt
     2041 ggtccttcag caggaaaatg ggttgaatta ccaattacca agtctccaaa gatagtgcat
     2101 ttctctgtgg gacatgacgg ctcgcatgcc cttttagttg cagaggatgg aagtgtgttc
     2161 ttcacaggat ctgccagcaa aggagaggat ggagagtcag ctaagagcag acggcagtcc
     2221 aaaccctata aacctaaaaa gattataaaa atggaaggga agatcgtggt gtgcacagcc
     2281 tgcaataacg ggagcagctc tgtgatctct aaggatggag aattgtacat gttcggaaaa
     2341 gatgccattt attctgatag ttcaagttta gtatctgatt tgaaaggcca ttttgtaact
     2401 caggtagcaa tgggcaaagc tcacacatgt gttttaatga agaatggaga ggtttggaca
     2461 tttggtgtaa ataataaagg acagtgtgga cgagacactg gtgctatgaa ccaaggaggg
     2521 aaagggtttg gagttgaaaa tatggcaaca gcaatggatg aagacctgga ggaagaacta
     2581 gatgagaaag atgagaagtc catgatgtgc cctccaggca tgcacaagtg gaagctggag
     2641 cagtgcatgg tgtgcaccgt gtgtggagac tgcacaggct atggtgccag ctgcgttagc
     2701 agtggtcgcc ctgatagagt tcctggaggg atctgtggat gtggttcagg agagtccggc
     2761 tgtgctgtgt gtggatgttg caaggcatgt gcaagggagt tggatggtca agaggcaaga
     2821 caaagaggga ttcttgatgc agtgaaagaa atgatacctt tagacctcct tttagctgtc
     2881 cctgtacctg gggttaatat tgaagaacat cttcaattaa gacaagaaga aaaacggcaa
     2941 cgtgtcatta gaagacacag attagaagat ggaagaggcc cccttgtatt tgctggtcct
     3001 atttttatga accaccgaga acaggctcta gccagactca gatcccatcc agctcagcta
     3061 aagcataaac gggacaagca caaagatgca agcggagaaa gaggggaaaa ggacgcaagc
     3121 aaagtcacaa cctacccgcc cggctctgtg aggtttgact gcgaggtccg ggcagtccag
     3181 gtcagctgtg gattccacca ctcagtggtt ctcatggaga atggagacgt ctatacattt
     3241 ggatatgggc agcatggcca gctgggacat ggggatgtca attccagggg atgccccacc
     3301 cttgttcaag ccttgccagg ccctagcaca caagtcactg ccggcagcaa ccacacggca
     3361 gtccttgtaa tggatggaca ggtcttcaca tttggaagtt tttctaaagg acagctgggg
     3421 cgccctattt tggatgtacc atattggaat gcaaaaccag ctcccatgcc taacattgga
     3481 tcaaaatatg gacggaaggc cacttggatt ggtgcaagtg gggaccagac tttcttacga
     3541 atcgatgaag cgctgataaa ttctcatgta cttgcaacat cagaaatttt tgctagcaaa
     3601 cacataatag gcttggtgcc tgcttctata tcagaacccc caccgtttaa atgtcttctg
     3661 ataaataaag tggatggaag ttgtaaaact ttcaatgact ctgaacaaga agatctgcaa
     3721 ggatttggtg tatgtcttga tccggtgtat gatgtgcttt ggaggtttcg accaagcacc
     3781 agagagctct ggtgctacaa tgcagtggtc gctgatgcca gacttccctc tgccacagac
     3841 atgcagtcca gttgttgtat tctaagtcct gagcttgctc tgccaacggg atcgagggct
     3901 ctgaccaccc gatctcatgc agccttgcat atcctgggtt gtcttgacac tttggcggcc
     3961 atgcaggact taaagatggg cattgcaagt atagaggagg agacccaagc agtgatgaaa
     4021 gtctattcca aggaagacta cagtatagtc aacaggtttg aaagtcatgg aggaggctgg
     4081 ggttactctg ctcactcagt agaagccata cgttttagtg ctgacactga cattttactt
     4141 ggtggtcttg gtctgtttgg aggaagagga gaatatactg ctaaaattaa gctgtttgag
     4201 ttgggtcctg atggaggaga tcatgaaaca gatggagacc tcctcgcaga gactgacgtg
     4261 ctggcttacg actgtgctgc tagagaaaaa tatgcaatga tgtttgatga gccagttctg
     4321 ctgcaagctg gatggtggta tgtggcatgg gctcgagtgt caggtcccag cagtgactgc
     4381 ggctctcacg gacaggcttc cattaccaca gatgacgggg tgatcttcca attcaagagt
     4441 tcaaagaagt caaataatgg caccgatgta aatgctggtc agatacctca gctgctctac
     4501 agactcccaa cctgtgatgg cagtacttca aaaggcaaac agcagacaag tgagcctgta
     4561 cacattttaa agagatcttt tgcaagaact gtctccgtgg agtgctttga gtcactgttg
     4621 agcattcttc actggagctg gacgacctta gtcttaggag tcgaagagct tagagggctg
     4681 aaggggttcc agttcactgc cacactcctt gatttagagc gactacgctt cgtggggacc
     4741 tgctgtctgc ggttattgcg tgtctacacc tgtgaaatat accccgtatc agctgtagga
     4801 aaagcagttg tagaagaaac tagcaaatta gctgagtgca ttggaaaaac aagaactttg
     4861 ttaagaaaga ttttatcaga aggagttgat cattgcatgg tgaagttgga taatgaccct
     4921 caggggtacc tcagccagcc cttgagtcta ctagagtccg tccttcagga gtgccataac
     4981 accttcactg cctgcttcca ctcattctac ccgacccctg cgctacagtg ggcctgcctc
     5041 tgtgatctgc tcaactgtct ggatcaggaa gcaaacttta agacatctag tagccggctc
     5101 ctggcagctg ttatgtccgc tctgtgtcac acatctgtga agctgacttc tctcttccct
     5161 attgcatatg atggcgaagt gttgctgcga tcaatagtta agcaagtcag cacagagaat
     5221 gagtcaacac tagttcatcg ttttcctctt ttagtgggac atatggaaaa gctcagccag
     5281 agtgaagaga acatctcggg gatgacgagc ttccgtgaag tgctggagaa gatgctggtc
     5341 attgttgtgc ttccggtgag aaatagcctt cggagggaga gtgagctgtt ttcctcacac
     5401 ctggtctcca acacctgcgg actcctggcc agtattgtca gtgagctgac tgcatcggcc
     5461 ctagggtctg aggttgatgg acttaattct cttcactctg taaaagccag tgctaaccga
     5521 ttcacaaaaa caagtcaggg aaggagctgg aacactggaa atggttcccc tgatgcaatc
     5581 tgttttgcag tagacaaacc tgggattgtc gttgtgggct tctctgtcta tggaggagga
     5641 ggtatacatg agtacgagtt ggaggtgctg gttgatgata gtgagcattc aggagattca
     5701 actcattctc acagatggac atccctagag ttagttaaag gaacttatac aaccgacgat
     5761 tcacccagtg acatagctga aatcagactt gacaaagttg ttcctttaaa ggaaaacgtt
     5821 aagtatgctg tgcgtctgag gaactacgga agccgcacag ccaatggcga tggaggaatg
     5881 accaccgtcc agtgccctga tggagtgact tttaccttca gcacgtgcag cttgagcagt
     5941 aatggcacca accaaaccag aggccaaatt ccccagatac tgtactatag gagtgaattt
     6001 gatggagatt tacagtccca gcttgtaagt aaagccaacg aggaagataa aaactgtagc
     6061 agagcactct ctgtggtaag cactgttgtc cgggctgcca aggacctgtt gcacagagct
     6121 cttgctgtgg atgctgatga cattccagaa ctgcttagct cctccagtct gttctccatg
     6181 ctgcttcccc ttattatagc ctacatagga ccagtagccg ctgctattcc caaggttgct
     6241 gtggaagtct ttggccttgt ccagcagctg cttccctcag ttgccgttct gaaccagaag
     6301 tatgcacccc ctgcattcaa tcccaatcag tcaacggata gcaccacagg caaccagccc
     6361 gagcaaggcc tctcggcgtg caccacttcc aatcactatg ccgtcatcga gagtgagcac
     6421 ccgtacaagc ctgcctgtgt gatgcactac aaggtgacgt tcccagagtg tgtcaggtgg
     6481 atgacaatcg agtttgaccc tcagtgtggc accgcgcagt cggaggacgt cctccgcttg
     6541 ctcacccctg tcagaaccat tcagaacgca gggtatggag caaaagtgac atctgctcat
     6601 gaaaacctca actcgtggat agagttaaag aaatactcag ggtcctctgg gtggcctact
     6661 atggttttag tgttgccagg aaatgaagcc cttttctcac tggaaactgc ctcagattat
     6721 gtgaaagatg acaaagcctc cttctatgga ttcaagtgtt tcgcaatcgg atatgaattc
     6781 agccctgggc ctgatgaggg agtcattcag ctggaaaaag aactagccaa tctcggtggg
     6841 gtttgtgccg cagccctgat gaagaaggac ctagcactgc ctattggtaa cgagctggag
     6901 gaggaccttg agattctgga agaggcagcg ttgcaggtgt gcaaaactca ctctggcatt
     6961 cttggcaagg gtttggctct ttctcactca cccaccatcc tagaggcact tgaaggaaac
     7021 ttgccacttc agatccaaag caatgagcag tcctttctgg atgacttcat tgcttgtgtt
     7081 ccaggatcaa gtgggggaag gcttgcaaga tggcttcagc ccgattccta tgctgatcct
     7141 cagaaaacat cattgatcct gaataaggat gatatccgct gtggctggcc caccaccata
     7201 actgttcaaa caaaagacca atatggcgat gtggttcatg ttcccaacat gaaggtggaa
     7261 gtgaaagctg tacctgtttc tcagaaaaaa acctctttgc aacaagagca agttaagaaa
     7321 tcccaaagag ttcctggcag tcctgcagca gcagcagctg catcttgcac caccgacatg
     7381 actttcggtg ggttggcgtc accaaagctg gatgtctcct atgaacccat gatagtcaag
     7441 gaggcacgct atatcgccat aacaatgatg aaggtatatg aaaactactc atttgaagaa
     7501 ctgcgttttg cctcaccaac tcctaaaagg cccagtgaaa acatgctcat tcgtgtcaat
     7561 aatgatggaa cttactgtgc aaattggacg ccaggggcta ttgggctcta cactgttcat
     7621 gtgaccattg atggcattga aatagatgct ggccttgaag taaaagtgaa agacccacca
     7681 aaagggatga ttccaccagg aactcagctc gtcaagccaa aggctgaccc tcaaccaaat
     7741 aagattcgaa aatttgtggc caaggacagt gctggtctcc gcatccggag ccacccttcc
     7801 cttcagagtg aacagattgg aatagtgaaa gttaatggaa ctatcacttt tattgatgag
     7861 atccacaatg atgatggtgt gtggttgaga ctgaacgagg agacaataag gaagtatgtt
     7921 cctaacatga atggctacac cgaagcctgg tgcctctctt tcaatcagca tcttggcaag
     7981 agccttctgg tccctgttga caatatcttt aatgctagcc aaggagtcag ggatttggac
     8041 gtattgtcat ggacttccaa agcttttttc ccccaggaac ctaaaacgac tactgatgac
     8101 tttttcaaag atgtgaacac ctgctgccca caggaagcag cagtgcgaga acgagaccac
     8161 ccgttcttga gaggtgggcc aggcatgtac aaggtagtga agacggggcc ttcaggccac
     8221 aacatcagaa gctgccctaa ccttagaggt atcccaattg gaatgttagt tctgggaaac
     8281 aaagtcaaag cagtgggaga ggtgaccagt gctgaaggca cgtgggtgca gctggataag
     8341 aacagcatgg tagaattctg tgagagcgat gaaggagagg cgtggtcctt agctagagac
     8401 agaggcggaa accagtacct ccggcatgaa gatgaacaag ttcttctgga tcagaattct
     8461 caaactcctc ctccaagccc gttctcagta caagctttca gtaaaggggc aagttgcagt
     8521 gcccaaggat ttgactatgg cctggggaat aacaaaggtg atcaactgag tgccatattg
     8581 aactctattc aatcacggcc caatctccca gctccttcca tctttgatca agctgcaaaa
     8641 cctccctcct ccctagtcca cagcccattt gtgttcggac agcccctttc cttccagcag
     8701 cgtcagcttc agagtgacag aggaactgtc tcaacatctt caagaccagt gtctacatca
     8761 gcaaagtcag agctgccctc caagaacagc agatcagtta aacctgatgg gcgtgtgagc
     8821 cggactactg ctgaccagaa gaagccacgg ggcacagaag gcttatctgc tagtgaatcc
     8881 ctcatgttaa aatctgatgc tgcaaagttg aggtcagact cccatagtag gtcactgtcc
     8941 cctaaccata acactttgca gacactgaag tctgatggaa gggtatcttc tagcttcagg
     9001 gctgaatccc caggaccagg ctctaggtca tcctctccta agcccaagac tctgccgact
     9061 cccaggtcta gcccatctgg tgctagctct ccacgctcct cctcaccgca ggataaaaat
     9121 ctacctcaga aaagcacagc tcctgctaag acaaaacttg acccacctcg ggagcgttcc
     9181 aagtcagact catatacact tgatccagat acgctccgta agaagaaaat gccccttaca
     9241 gaaccattaa gggggcgatc cacatcacca aaaccaaaac cagtaccaaa ggatcctaaa
     9301 ggctcccccg ggtctgaaaa cagagcccct tctccccatg tggtccagga aaaccttcac
     9361 agtgaggtag tagaagtctg tacttcaagt actttaaaga caaatggtgt cacagacagc
     9421 acctgtgatg acagcaatga ttttaagagt gtggatgaag gttcaaataa agtgcacttc
     9481 agcataggaa aagcaccact gaaagatgaa caggaaatga gagcatcacc caaaataagt
     9541 cggaaatgtg ctaatagaca caccaggccc aaaaaagaaa agtctaactt tcttttcaaa
     9601 ggagatggag ccaaatcttt agagccagcc aagcaagcca tgtccccgtc cgtggctgag
     9661 tgtgcccgag ctgtctttgc ctcttttctg tggcatgaag gcatagtaca tgatgcaatg
     9721 gcctgctctt ccttcctgaa gtttaatcct gaactttcca aagaacatgc tcccataaga
     9781 agtagtttga atagccagcc acccacagag gaaaaggaaa tcaagttaaa aaatagacat
     9841 tcgttggaaa tatcatctgc cctaaatatg ttcaacattt cacctcacgg accagacata
     9901 tccaagatgg gaagtatcaa caaaaataag gtcctgtcta tgcttaagga gccacctcta
     9961 catgagaagt gtgaagacgg aaaatcggaa gccacttttg aaatgtccat gcatcactca
    10021 gtgaagtcta ggtctccgct ccccttaaca ttacaacact tagtggcctt ctgggaggac
    10081 atctctttgg ctacaatcaa agctgcttcc cagaatatga tttttccaag tccaggttcc
    10141 tgtgcagtcc ttaaaaagaa agaatgtgag aaagagaata aaaaaacgaa aaaggaaaaa
    10201 aagaaaaaag aaaagacaga aattcggcca aggggcaatt tgtttggtga aatggcccag
    10261 ctggcagtag gagggccaga gaaagatacc atctgtgagc tatgtgggga atcccaccca
    10321 tacccagtga cctatcacat gagacaagct cacccaggtt gtggccgata tgctggtgga
    10381 caaggataca atagcattgg gcatttttgt ggaggatggg ctggtaactg tggtgatggg
    10441 ggaatgggag gaagcacttg gtacctcgta tgtgatcgct gtagagaaaa atacctccgt
    10501 gaaaaacagg ctgctgcaag ggaaaaggtc aaacaatcga gaagaaagcc aatgcaagta
    10561 aagacgcccc gtgccttgcc caccatggaa gcacaccagg tgatcaaggc caatgccctc
    10621 ttcctgctgt ccctgagcag tgcggccgag cccagcatct tgtgctacca ccctgcaaag
    10681 ccattccagt ctcagctgcc cattgtgaag gaaggcgttt ctgaggccct tcctgttaaa
    10741 atgccctgtc tctacttgca gacattagct aggcaccacc atgaaaattt tgtgggctat
    10801 caagatgaca acctattcca ggatgaaatg agatatctgc gttcaacgtc tgtccctgcc
    10861 ccgtacatct cagtaactcc tgatgcaagt cccaatgtct ttgaagagcc ggagagcaat
    10921 atgaagtcga tgccaccaag tttggaaacg agcccgataa ctgacaccga cctggctaag
    10981 agaactgtct tccagaggtc atactcagtt gtcgcttcgg aatatgataa acaacactcc
    11041 attttacctg cacgagttaa agccatccct agaaggagag tgaacagtgg agacacggtt
    11101 gggtcttctc tcttgcgaca tccgtcaccg gagctttccc ggcttatatc agcccacagc
    11161 tctctctcca aaggagagcg aaacttccag tggccagtct tagctttcgt catacagcat
    11221 catgatttag aagggctgga aatcgcaatg aagcaggcct taaggaagtc ggcttgccgt
    11281 gtgtttgcta tggaggcatt caactggctt ctctgtaatg tcatccaaac aacgtctctg
    11341 catgacattc tctggcactt tgtggcagca ctgactcctt ctcctgtaga ggcagaggaa
    11401 gacgaggatg aagataataa atccagtaaa gaaaatgcag agcaagagaa ggacacaagg
    11461 gtgtgtgagc acccgctgtc agacatcgtg attgcaggcg aggctgctca ccctttgcca
    11521 cacacctttc accgcttact tcagaccatc tccgacctca tgatgtcgct ccctagtggc
    11581 agttccttgc agcaaatggc cctaagatgc tggagcctta agttcaagca gtctgaccac
    11641 cagttcctcc atcagagcaa tgtcttccat catatcaaca acatcttgtc gaagtcagac
    11701 gacggagaca gtgaggagag cttcagcatc agtatccagt ctggctttga agccatgaac
    11761 caggagttat gcatagttat gtgcttaaag gacttgacca gtatcgttga cataaaaaca
    11821 tcaagtcgac ctgccatgat tggcagtttg acagatggct ccacagaaac cttttgggaa
    11881 tcaggagatg aagataaaaa taaaactaaa accatcacta tcaactgtgt gaagggaatt
    11941 aatgcccgtt atgtatctgt tcatgtggac aattcccggg atcttgggaa taaagttacc
    12001 tcgatgacct tcctgactgg taaagcagta gaagatttgt gcagaataaa gcaggtcgac
    12061 ttggattcca ggcacattgg ctgggtaaca agtgaactcc ctggagggga taatcacatc
    12121 atcaaaattg agttaaaggg cccagaaaat acattaagag ttcgacaagt aaaagtcctg
    12181 ggttggaaag acggtgaaag cacaaagatt gctggccaga tctcagccag tgtggctcag
    12241 cagaggagct gcgaggccga gaccctgcgg gtgttcagac tcatcacctc tcaggtgttt
    12301 gggaagctca tctctgggga tgctgaacct acaccagagc aagaggaaaa ggcgctcctg
    12361 tcatcaccgg aaggagagga aaaagcaaca tctgacgctg acctgaagga acatatggtt
    12421 ggaatcatat tcagcaggag caaactgact aacttacaaa agcaggtttg tgctcacatt
    12481 gtccaagcta ttcgcatgga agccacacgg gtccgtgagg agtgggagca tgccatatcc
    12541 agcaaggaga acgccaattc ccagcccagc gatgaggacg cctcctcgga tgcctactgc
    12601 ttcgagctgc tctccatggt cttggcgctg agtggctcca acgtgggcag gcagtacctg
    12661 gcgcagcagc tgaccctgct tcaggacctc tgctccttgc tccacacagc ctcgccgagg
    12721 gtccagagac aggtgacctc cttactaaga cgcgttttgc ctgaagtgac tcctaaccgt
    12781 ctggccagta tcataggagt gaagtccctc cccccagctg acatcagtga catcattcac
    12841 tcaactgaga agggagactg gaataagctg ggaatcttgg acatgtttct gggatgtatt
    12901 gccaaggctc tcactgtcca gctcaaagcc aaagggacca ccatcacagg gacagctggc
    12961 accactgtgg gcaaaggagt tacaacagtc accctgccaa tgattttcaa ctccagctac
    13021 ctccgacgcg gcgaaagtca ttggtggatg aaaggctcca ctcccactca gatctcagag
    13081 atcatcatca agctgatcaa ggatatggcc gcaggtcacc tgtcagaagc ctggtcccga
    13141 gtgacaaaaa atgctattgc agagaccatc attgccctga ccaagatgga ggaagagttc
    13201 aggtccccag tgaggtgtat tgccacaacc agactctggc ttgccctggc gtcactgtgt
    13261 gttcttgatc aggaccatgt ggatcgcctc tcctcgggca ggtggatggg aaaggacggg
    13321 cagcagaagc aaatgcctat gtgtgataac catgatgacg gggagactgc ggctatcatc
    13381 ttatgcaaca tctgtgggaa tctgtgcact gactgtgaca gattcctgca tctgcatcga
    13441 cggacgaaaa ctcaccaaag acaggtcttc aaagaagaag aagaagctat aaaggttgac
    13501 cttcatgaag gctgtggtag aacaaaactg ttttggttga tggcattagc agattctaaa
    13561 acaatgaagg caatggtgga attccgagaa cacacaggca aacccaccac aagcagctca
    13621 gaagcatgcc gcttctgtgg gtccaggagt ggaacggagt tatctgctgt tggcagtgtt
    13681 tgttctgatg cagactgcca ggagtacgcg aagatcgcct gcagtaagac acatccttgt
    13741 ggacatccat gcggaggtgt cagaaatgaa gaacactgtt tgccctgtct gcatggctgt
    13801 gataagaacg ctaccacatt gaaacaagat gcggacgaca tgtgcatgat ctgcttcact
    13861 gaggcgctct ctgcagcacc cgccattcag ttggactgca gtcatgtatt ccacttacaa
    13921 tgctgtcggc gagtgttgga aaacaggtgg cttggtccaa ggataacgtt tggattcata
    13981 tcgtgtccca tttgcaagaa caaaataaat catatagtat taaaagacct gcttgatcca
    14041 ataaaagagc tctatgaaga tgtcagaaga aaagccttaa tgagattgga gtacgaaggg
    14101 ctgcataaga gtgaagcgat cacgacgccg ggcgtcaggt tttacaatga tccagccggc
    14161 tatgccatga acagatacgc atattatgtt tgctacaaat gcagaaaggc atattttggt
    14221 ggtgaagctc gctgtgatgc tgaggctgga caaggagacg actacgaccc cagagagctc
    14281 atctgtggag cctgttctga tgtgtctagg gctcagatgt gtcccaaaca tggaacagac
    14341 tttctagaat acaaatgtcg ctactgctgt tcagtggctg tcttcttctg ttttggaaca
    14401 acacatttct gcaatgcttg tcatgatgat tttcaaagaa tgaccagcat tcctaaggaa
    14461 gagctcccac actgtcctgc aggtcccaaa ggcaaacagc tagaaggaac tgaatgtcca
    14521 ctccatgttg ttcatccgcc cacgggggaa gagtttgctc ttggttgtgg agtgtgcaga
    14581 aatgctcaca cgttttagaa ctttcagatc ctttgtctac aaagaggata gttgccttca
    14641 tcccctggga ggatgcagtg aaacttaaac tctgctcagg ataagaacgg gaccatttta
    14701 cattctgaaa acgaaccatt tccagtgcag gagtgatgcc aaatactgtg tacataattc
    14761 ttgctacgaa cgtttcccca ttgttttggt ttatcatctt tgaaccaaga catcaaactt
    14821 gtgaggtgtt tgcatgtggc cattaccgtc actggcctgt ggagcattgg acatttatag
    14881 ataattgata taaaaggatc tccatactca tggactaaga atgatgctgg ctttcaagca
    14941 aaaaaagaaa aataatcact gtttattgta tactgccttt ttgtaatcct gtacaattgc
    15001 atcacgggtg ggtataaaaa gaggaatatt ctggtttctt tcctagactg ttatttaaaa
    15061 aaaaaaattg tgttagtaag gcctataatt gtaataagta tcagactgta tataaagcta
    15121 tcagtgtttg tcctgtatga gaattactaa atgacacagc agtctcattt aaacctgtag
    15181 gttacgtttg agcctgaagc tctaatgcag tgcaatactg ggtgtgcctc actaccttgc
    15241 agctgtcagc atattggaat gtacgtcagt aaaccactgt gctctacaca gtgagagcgt
    15301 cttatgcttg tgtgacgtgg tgttttcaaa gacaatgtaa acaacttatg aagcctaaag
    15361 cccacttata acacactcat aacttccctg tttagggaaa taaaaatacc agtaaagcac
    15421 a
//
