LOCUS       NM_013160               2303 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus MAX interactor 1, dimerization protein (Mxi1),
            mRNA.
ACCESSION   NM_013160 XM_346590 XM_347361
VERSION     NM_013160.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2303)
  AUTHORS   Cui,W., Dai,X., Marcho,C., Han,Z., Zhang,K., Tremblay,K.D. and
            Mager,J.
  TITLE     Towards Functional Annotation of the Preimplantation Transcriptome:
            An RNAi Screen in Mammalian Embryos
  JOURNAL   Sci Rep 6, 37396 (2016)
   PUBMED   27869233
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2303)
  AUTHORS   Dugast-Darzacq,C., Pirity,M., Blanck,J.K., Scherl,A. and
            Schreiber-Agus,N.
  TITLE     Mxi1-SRalpha: a novel Mxi1 isoform with enhanced transcriptional
            repression potential
  JOURNAL   Oncogene 23 (55), 8887-8899 (2004)
   PUBMED   15467743
REFERENCE   3  (bases 1 to 2303)
  AUTHORS   Kwitek,A.E., Gullings-Handley,J., Yu,J., Carlos,D.C., Orlebeke,K.,
            Nie,J., Eckert,J., Lemke,A., Andrae,J.W., Bromberg,S., Pasko,D.,
            Chen,D., Scheetz,T.E., Casavant,T.L., Soares,M.B., Sheffield,V.C.,
            Tonellato,P.J. and Jacob,H.J.
  TITLE     High-density rat radiation hybrid maps containing over 24,000
            SSLPs, genes, and ESTs provide a direct link to the rat genome
            sequence
  JOURNAL   Genome Res 14 (4), 750-757 (2004)
   PUBMED   15060019
REFERENCE   4  (bases 1 to 2303)
  AUTHORS   Manni,I., Tunici,P., Cirenei,N., Albarosa,R., Colombo,B.M., Roz,L.,
            Sacchi,A., Piaggio,G. and Finocchiaro,G.
  TITLE     Mxi1 inhibits the proliferation of U87 glioma cells through
            down-regulation of cyclin B1 gene expression
  JOURNAL   Br J Cancer 86 (3), 477-484 (2002)
   PUBMED   11875718
REFERENCE   5  (bases 1 to 2303)
  AUTHORS   Yin,X., Landay,M.F., Han,W., Levitan,E.S., Watkins,S.C.,
            Levenson,R.M., Farkas,D.L. and Prochownik,E.V.
  TITLE     Dynamic in vivo interactions among Myc network members
  JOURNAL   Oncogene 20 (34), 4650-4664 (2001)
   PUBMED   11498788
REFERENCE   6  (bases 1 to 2303)
  AUTHORS   Li,X.J., Wang,D.Y., Zhu,Y., Guo,R.J., Wang,X.D., Lubomir,K.,
            Mukai,K., Sasaki,H., Yoshida,H., Oka,T., Machinami,R., Shinmura,K.,
            Tanaka,M. and Sugimura,H.
  TITLE     Mxi1 mutations in human neurofibrosarcomas
  JOURNAL   Jpn J Cancer Res 90 (7), 740-746 (1999)
   PUBMED   10470286
REFERENCE   7  (bases 1 to 2303)
  AUTHORS   Wang,Y., Toury,R., Hauchecorne,M. and Balmain,N.
  TITLE     Expression and subcellular localization of the Myc superfamily
            proteins: c-Myc, Max, Mad1 and Mxi1 in the epiphyseal plate
            cartilage chondrocytes of growing rats
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 43 (2), 175-188 (1997)
   PUBMED   9130602
REFERENCE   8  (bases 1 to 2303)
  AUTHORS   Eagle,L.R., Yin,X., Brothman,A.R., Williams,B.J., Atkin,N.B. and
            Prochownik,E.V.
  TITLE     Mutation of the MXI1 gene in prostate cancer
  JOURNAL   Nat Genet 9 (3), 249-255 (1995)
   PUBMED   7773287
REFERENCE   9  (bases 1 to 2303)
  AUTHORS   Zervos,A.S., Gyuris,J. and Brent,R.
  TITLE     Mxi1, a protein that specifically interacts with Max to bind
            Myc-Max recognition sites
  JOURNAL   Cell 72 (2), 223-232 (1993)
   PUBMED   8425219
  REMARK    Erratum:[Cell. 1994 Oct 21;79(2):following 388.. PMID: 7954804]
REFERENCE   10 (bases 1 to 2303)
  AUTHORS   von Boehmer,H., Sprent,J. and Haas,W.
  TITLE     The influence of H-2 gene products on cell-mediated and humoral
            immune responses
  JOURNAL   Cold Spring Harb Symp Quant Biol 41 Pt 2, 539-545 (1977)
   PUBMED   70302
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC081824.1.
            
            On Mar 27, 2005 this sequence version replaced NM_013160.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC081824.1, AF003008.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2303
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q55"
     gene            1..2303
                     /gene="Mxi1"
                     /gene_synonym="MXI-WR"
                     /note="MAX interactor 1, dimerization protein"
                     /db_xref="GeneID:25701"
                     /db_xref="RGD:3128"
     exon            1..120
                     /gene="Mxi1"
                     /gene_synonym="MXI-WR"
                     /inference="alignment:Splign:2.1.0"
     CDS             48..734
                     /gene="Mxi1"
                     /gene_synonym="MXI-WR"
                     /note="Max interacting protein 1; Max interactor 1-like"
                     /codon_start=1
                     /product="max-interacting protein 1"
                     /protein_id="NP_037292.2"
                     /db_xref="GeneID:25701"
                     /db_xref="RGD:3128"
                     /translation="MERVRMINVQRLLEAAEFLERRERECEHGYASSFPSMPSPRLQH
                     SKPPRRLSRAQKHSSGSSNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTR
                     HTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKRRLEQLQGPQEMERIRMDS
                     IGSTISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDIDDHSSLQSIGSDEGYS
                     SASVKLSFTS"
     exon            121..253
                     /gene="Mxi1"
                     /gene_synonym="MXI-WR"
                     /inference="alignment:Splign:2.1.0"
     exon            254..283
                     /gene="Mxi1"
                     /gene_synonym="MXI-WR"
                     /inference="alignment:Splign:2.1.0"
     exon            284..398
                     /gene="Mxi1"
                     /gene_synonym="MXI-WR"
                     /inference="alignment:Splign:2.1.0"
     exon            399..570
                     /gene="Mxi1"
                     /gene_synonym="MXI-WR"
                     /inference="alignment:Splign:2.1.0"
     exon            571..2278
                     /gene="Mxi1"
                     /gene_synonym="MXI-WR"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gccgtctgtg gcgcctcctg tcggccgggg gcgggagcgc ggagcccatg gagcgggtgc
       61 ggatgatcaa cgtgcagcgc ctgctggagg ccgcggagtt tttggagcgc agggagcgag
      121 agtgtgaaca tggctacgct tcatcattcc cctccatgcc gagcccccgg ctacagcact
      181 caaagccccc acggaggttg agccgggcac agaaacacag cagtgggagc agcaacacca
      241 gcactgccaa cagatctaca cacaatgagt tggaaaagaa tcgacgagct cacctgcgcc
      301 tgtgtttaga acgcttaaaa gttctgatcc cgctgggccc agactgcacc aggcacacaa
      361 cacttggttt gctcaacaaa gccaaagcac acatcaagaa acttgaagaa gccgaaagga
      421 agagccagca ccagcttgag aacttggaac gagaacagag atttttaaag cggcgactgg
      481 aacagctgca gggtcctcag gagatggagc ggatacgaat ggacagcatt ggatcaacga
      541 tctcctcaga tcgctcggat tcagagcgag aggagattga agtggatgtg gaaagcacag
      601 agttctccca tggagaagtg gacaacatca gtaccaccag catcagcgac atcgatgacc
      661 acagcagcct gcagagtatt gggagtgacg agggctactc cagtgccagt gtcaaactct
      721 ccttcacgtc ctagaaccca gcatgacata acagtgcagg gcgaagtgct cactgggcca
      781 gttcaatacc gtctctcaaa ttgggttcat gacgcagtct cctctttaaa actaaaaact
      841 atacttgaac aaaagggtca gaagacctgt atttaagcaa atacttaaaa agtggggtag
      901 agcctccccg gtagaacaaa tactcctgta tttggaaaga atacagtttc taacagcagc
      961 agaaatgtgt gtggttatct tgagttgacg tggttgactt aagagacaat ggagactcca
     1021 ttctcctgtt gtagtttgct cactccgtgt tgagcagaca tttaaggata gggttatgaa
     1081 cccttcctga gcttcttggt cctagaaaca aaatcaaact tagagtaagg agaagacagg
     1141 ataatcaggc attaatcttg gatagctaaa gagctattaa aactcagcct ctgtgtatca
     1201 tgaagcctgt ggatgatcaa ttcttttaaa aaatgaattt ttaaaaagct catatcgtgc
     1261 tctacaaaag gagagactcc catgaagcct tttgaacgag atcatcatgc agctcagctt
     1321 tctgttggat tccatgctaa gccagctaac cttacctgca ttgatagcac tagagcaggc
     1381 aagcacccgc tcgccaccct tcggccacgt aggggcagcc catgcatgac agcctgaatc
     1441 acaggaggaa cagctccgtg tgcgagcctc ggtgtctgcg cggatctgag gagctgtgca
     1501 cgcagtgtag caggccaagg tctgagccac cacagcattt ttatttgaga ttttgataac
     1561 tgtttgtatg tgttgaaaac caaaatgaca tctttttaaa gcttgtccat aagtaaacat
     1621 agatgtcttt tatagtggaa taaaacacgt gggggaaatc atctattttg atgcagcatt
     1681 tgataatgat aaacacctca cgcctcactc ttttcagtgc gcaggacgga tgaggtctgg
     1741 gctgggtaga cgaaggcaat gctgtttttg ttttctttag gaccattccc ttttaccagc
     1801 ttttaaccgt ctgatacccg tggtaggcac actatcctag ttaacatagt tatgttccgc
     1861 acttgtctca tttaatgtaa agatctgcat tttctacagg cagtttcctc cccacaatcc
     1921 cactgtgcag gtgctactgt tgctctcaca aatacctgca gaaatgttat cttctgggtg
     1981 agacttccag cccgcactcc gtgtcatgtg ctccctcctt tcaaactcga aggtttccct
     2041 ctgggccact gctttgctcc gggaagcctt tctggatacc ttaccccaag ctgttcggac
     2101 tttgtattct ttaaataatt taactaccct taattactta aaaaaaaaag ctttatgatt
     2161 ttcataactt attgccgatt ttaatgggtt gttaatttca gtcctgtagt tttattttat
     2221 gtttagatag ggctgggcaa ggagaaagaa aataaaaaca accatattca gcagtgcaaa
     2281 aaaaaaaaaa aaaaaaaaaa aaa
//
