LOCUS       NM_001419868           11534 bp    mRNA    linear   ROD 12-JUN-2023
DEFINITION  Rattus norvegicus mucin 5AC, oligomeric mucus/gel-forming (Muc5ac),
            mRNA.
ACCESSION   NM_001419868
VERSION     NM_001419868.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 11534)
  AUTHORS   Xu K, Liu XN, Zhang HB, Zhu XP and Zhang XJ.
  TITLE     Tear film instability is associated with weakened colocalization
            between occludin and MUC5AC in scopolamine-induced dry eye disease
            (DED) rats
  JOURNAL   Int Ophthalmol 43 (2), 463-473 (2023)
   PUBMED   35908134
  REMARK    GeneRIF: Tear film instability is associated with weakened
            colocalization between occludin and MUC5AC in scopolamine-induced
            dry eye disease (DED) rats.
REFERENCE   2  (bases 1 to 11534)
  AUTHORS   Wu X, Yao C, Kong J, Tian Y, Fan Y, Zhang Z, Han J and Wu S.
  TITLE     Molecular mechanism underlying miR-130b-Sp1 transcriptional
            regulation in LPS-induced upregulation of MUC5AC in the bile duct
            epithelium
  JOURNAL   Mol Med Rep 23 (2) (2021)
   PUBMED   33300069
  REMARK    GeneRIF: Molecular mechanism underlying miR130bSp1 transcriptional
            regulation in LPSinduced upregulation of MUC5AC in the bile duct
            epithelium.
REFERENCE   3  (bases 1 to 11534)
  AUTHORS   Mendez A, Rojas DA, Ponce CA, Bustamante R, Beltran CJ, Toledo J,
            Garcia-Angulo VA, Henriquez M and Vargas SL.
  TITLE     Primary infection by Pneumocystis induces Notch-independent Clara
            cell mucin production in rat distal airways
  JOURNAL   PLoS One 14 (6), e0217684 (2019)
   PUBMED   31170201
  REMARK    GeneRIF: Frequency of distal airways Clara cells was maintained
            while mRNA levels for the mucin-encoding genes Muc5B and Muc5ac in
            lung homogenates increased 1.9 and 3.9 times at 60 days of
            Pneumocystis infection.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 11534)
  AUTHORS   Ferretti VA, Segal-Eiras A, Barbeito CG and Croce MV.
  TITLE     Temporal and spatial expression of Muc2 and Muc5ac mucins during
            rat respiratory and digestive tracts development
  JOURNAL   Res Vet Sci 104, 136-145 (2016)
   PUBMED   26850552
  REMARK    GeneRIF: Rat Muc2 was expressed in fetal intestinal goblet cells of
            surface epithelium of villi and developing Lieberkuhn crypts. In
            neonates and adults, Muc2 was expressed at luminal goblet cells of
            small and large intestine and at gastric mucous and glandular
            cells. Muc5ac protein was observed in embryonic gastric and lung
            samples; expression increased during development and postnatal and
            adult life.
REFERENCE   5  (bases 1 to 11534)
  AUTHORS   Kania N, Setiawan B, Widjadjanto E, Nurdiana N, Widodo MA and
            Kusuma HM.
  TITLE     Subchronic inhalation of coal dust particulate matter 10 induces
            bronchoalveolar hyperplasia and decreases MUC5AC expression in male
            Wistar rats
  JOURNAL   Exp Toxicol Pathol 66 (8), 383-389 (2014)
   PUBMED   24975055
  REMARK    GeneRIF: concluded that subchronic inhalation of coal dust
            particulate matter 10 induces a decrease in expression of MUC5AC in
            male rats.
REFERENCE   6  (bases 1 to 11534)
  AUTHORS   Yonezawa S, Horinouchi M, Osako M, Kubo M, Takao S, Arimura Y,
            Nagata K, Tanaka S, Sakoda K, Aikou T and Sato E.
  TITLE     Gene expression of gastric type mucin (MUC5AC) in pancreatic
            tumors: its relationship with the biological behavior of the tumor
  JOURNAL   Pathol Int 49 (1), 45-54 (1999)
   PUBMED   10227724
REFERENCE   7  (bases 1 to 11534)
  AUTHORS   Inatomi T, Tisdale AS, Zhan Q, Spurr-Michaud S and Gipson IK.
  TITLE     Cloning of rat Muc5AC mucin gene: comparison of its structure and
            tissue distribution to that of human and mouse homologues
  JOURNAL   Biochem Biophys Res Commun 236 (3), 789-797 (1997)
   PUBMED   9245735
REFERENCE   8  (bases 1 to 11534)
  AUTHORS   Guzman K, Bader T and Nettesheim P.
  TITLE     Regulation of MUC5 and MUC1 gene expression: correlation with
            airway mucous differentiation
  JOURNAL   Am J Physiol 270 (5 Pt 1), L846-L853 (1996)
   PUBMED   8967520
REFERENCE   9  (bases 1 to 11534)
  AUTHORS   Balague C, Audie JP, Porchet N and Real FX.
  TITLE     In situ hybridization shows distinct patterns of mucin gene
            expression in normal, benign, and malignant pancreas tissues
  JOURNAL   Gastroenterology 109 (3), 953-964 (1995)
   PUBMED   7657125
REFERENCE   10 (bases 1 to 11534)
  AUTHORS   Balague C, Gambus G, Carrato C, Porchet N, Aubert JP, Kim YS and
            Real FX.
  TITLE     Altered expression of MUC2, MUC4, and MUC5 mucin genes in pancreas
            tissues and cancer cell lines
  JOURNAL   Gastroenterology 106 (4), 1054-1061 (1994)
   PUBMED   8143972
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000044.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by
            NM_001419868.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: lack of evidence for use of
                                                upstream AUG
            inferred exon combination        :: based on alignments, homology
            RefSeq Select criteria           :: based on expression, longest
                                                protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-112               JACYVU010000044.1  23793593-23793704
            113-187             JACYVU010000044.1  23794342-23794416
            188-247             JACYVU010000044.1  23795153-23795212
            248-509             JACYVU010000044.1  23795542-23795803
            510-624             JACYVU010000044.1  23796051-23796165
            625-715             JACYVU010000044.1  23796551-23796641
            716-825             JACYVU010000044.1  23797252-23797361
            826-1039            JACYVU010000044.1  23797482-23797695
            1040-1165           JACYVU010000044.1  23797791-23797916
            1166-1280           JACYVU010000044.1  23798103-23798217
            1281-1419           JACYVU010000044.1  23798403-23798541
            1420-1530           JACYVU010000044.1  23799729-23799839
            1531-1600           JACYVU010000044.1  23800313-23800382
            1601-1738           JACYVU010000044.1  23800468-23800605
            1739-1903           JACYVU010000044.1  23800684-23800848
            1904-1998           JACYVU010000044.1  23802703-23802797
            1999-2125           JACYVU010000044.1  23803326-23803452
            2126-2381           JACYVU010000044.1  23803720-23803975
            2382-2434           JACYVU010000044.1  23804122-23804174
            2435-2535           JACYVU010000044.1  23804589-23804689
            2536-2687           JACYVU010000044.1  23805012-23805163
            2688-2826           JACYVU010000044.1  23805361-23805499
            2827-2940           JACYVU010000044.1  23805592-23805705
            2941-3120           JACYVU010000044.1  23805812-23805991
            3121-3360           JACYVU010000044.1  23807838-23808077
            3361-3517           JACYVU010000044.1  23808409-23808565
            3518-3646           JACYVU010000044.1  23809315-23809443
            3647-3803           JACYVU010000044.1  23809688-23809844
            3804-3847           JACYVU010000044.1  23810616-23810659
            3848-4033           JACYVU010000044.1  23810770-23810955
            4034-7252           JACYVU010000044.1  23812050-23815268
            7253-8686           JACYVU010000044.1  23815869-23817302
            8687-8880           JACYVU010000044.1  23817524-23817717
            8881-9055           JACYVU010000044.1  23818183-23818357
            9056-9306           JACYVU010000044.1  23818719-23818969
            9307-9490           JACYVU010000044.1  23819062-23819245
            9491-9692           JACYVU010000044.1  23819491-23819692
            9693-9871           JACYVU010000044.1  23820286-23820464
            9872-9962           JACYVU010000044.1  23820976-23821066
            9963-10063          JACYVU010000044.1  23821191-23821291
            10064-10095         JACYVU010000044.1  23821418-23821449
            10096-10258         JACYVU010000044.1  23821949-23822111
            10259-10363         JACYVU010000044.1  23822463-23822567
            10364-10401         JACYVU010000044.1  23822784-23822821
            10402-10524         JACYVU010000044.1  23823351-23823473
            10525-10623         JACYVU010000044.1  23823550-23823648
            10624-10743         JACYVU010000044.1  23824069-23824188
            10744-10801         JACYVU010000044.1  23824389-23824446
            10802-10910         JACYVU010000044.1  23824550-23824658
            10911-11534         JACYVU010000044.1  23825109-23825732
FEATURES             Location/Qualifiers
     source          1..11534
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q41"
     gene            1..11534
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /note="mucin 5AC, oligomeric mucus/gel-forming"
                     /db_xref="GeneID:682837"
                     /db_xref="RGD:62001"
     exon            1..112
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     CDS             40..11193
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /note="mucin 5, subtypes A and C,
                     tracheobronchial/gastric; mucin-5AC"
                     /codon_start=1
                     /product="mucin-5AC precursor"
                     /protein_id="NP_001406797.1"
                     /db_xref="GeneID:682837"
                     /db_xref="RGD:62001"
                     /translation="MGVGRRKLAPFWVLALALTFNQHTGQALEDTRKSHLEHYSDLSQ
                     PQGHVGTPLNRVTIIPPLKTIPVVRAFNPAHTRRVCSTWGNFHYKTFDGQVFYFPGLC
                     NYVFSEHCGAAYEDFNIQLRRGLESNSTTLSRVIMKLDGLVVELTKSSVLVNNHPVQL
                     PFSQSGVLIELSNGYLKVVARLGLVFMWNDDDSLLLELDTKYANKTCGLCGDFNGSPE
                     SSEFLSHNVRLTPLEFGNFQKMDGPTEQCQDPLPVPQKNCSIRSSICEEILKGQLFSN
                     CAALVDISSYLEACQQDLCLCESSDPSNCICHTLAEYSRQCAHAGGQPQNWRGPNLCP
                     QTCLLNMEYQECGSPCVDTCSNPQHSQVCEDHCVAGCFCPEGMVLDDSNQTGCVPVSQ
                     CACLYNGTLYAPGTSYSTDCTNTCSGGQWSCQEVPCSGTCSVMGGSHISTFDERQYTV
                     HGDCSYVLCKPYDSNAFTVLAELRKCGLTESETCLKTVTLNLGGGKTVITVKATGEVF
                     VNQIYTQLPVSTANATFFRPSTFFIIGQTNLGLQLEIQLHPIMQVSVRIAPEFRGLTS
                     GLCGNFNSMQADDFQTISGVVEGTAAAFFNTFKTQAACPNVKNIFEDPCSLSVENEKY
                     AQHWCSQLTDANGPFSQCHATVNPSTFFSNCMFDTCNCEKSEDCLCAALSSYVRACAA
                     KGVLLSDWREGICEKPTITCPKSMTYQYHISTCQPTCRSLSEEDVTCHVNFIPVDGCT
                     CPKGTFLDDSGKCVQATSCPCYYKGSPVPNGESVHDNGAICTCTQGALTCIGGPVLTP
                     VCDAPMIYFDCRNATPGDTGAGCQKSCHTLDMTCYSSECVPGCVCPNGLVADGNGSCV
                     VAEDCPCVHNEATYRPGETIQVGCNNCTCENRMWQCTDKPCLATCAVYGDGHYITFDG
                     QRYSFSGDCEYTLLQDNCGGNGSSQDAFRVVTENIPCGTTGTTCSKGIKIFLGSYELK
                     LSDSKMEVVQKGVGQEPPYFVHQMGNYLVVETDIGLVLLWDKKTSIFLRLSPEFKGKV
                     CGLCGNFDDNAINDFTTRSQSVVSDMLEFGNSWKLSPSCPDASVSKDPCTANPYRKSW
                     AQKQCSIINSATFSACHAHVEPAKYYEACVNDACACDSGGDCECFCTAVAAYAQACHE
                     VGVCVSWRTPDICPLFCDYYNPEGQCEWHYQPCGAPCMRTCQNPTGQCLQDLRGLEGC
                     YPKCPPTAPIFDEGTMQCVSNCTVSPSPCRVNGKLYRPGTPIPSDENCYSCVCTESGV
                     NCTHDAGACVCTYNGQRYHPGDTIYHTTDGMGGCISAHCRDNGTIERIVDTCSSTSPP
                     PPTTFSFSTTLVMTSMQPSSTHSSPTPSVVYPGSPSKAVLTASSVSSVKTPETTSVLT
                     TSTSASTLTMPACQEECLWSPWMDISRPGRGIDSGDFDTLENLHAHGYQICPVPKAVE
                     CRAEDNPGVPFHALQQHVECSTTVGLICYNSDQVSGLCDNYQIKIQCCTPINCPTSTG
                     PTQTTHLIVSRTSTMEDTTSSVPVTSTEHTYSTVASSPSTHTPGPSPSSSVPSSSAPA
                     RSTPTPVSSTTVKTTLPTTSPMPEPTSATSSVSISTLGSTLASPEITHGCRKELCNWT
                     DWIDGSYPEPGRSSGDFDTFVNLRAKGYKFCEKPWNVECRAQFFPNTPLQELGQDVTC
                     SREVGLICLNKNQLPPICYNYEIRIECCTIVNICSTTSATTQPTSHGVSIKTKTNWIT
                     NTYSFSTENTSGHSTVINTKTWVTGSTHTTPQPGTRPTPSTVSTQDTSTSSVQTDSTT
                     SSSHTSSPNTGRVSTTHTTHTSSPPTGGTSPTSTTHTSSPPTGGTSPTSTTHTSSPPT
                     GGTSPTSTTHTSSPPTGGTSPTSTTHTSSPPTGGTSPTSTTHTSSPPTGGTSPTSTTH
                     TSSPNTGRVSTTHTTHTSSPPTGGTSPTSTTHTSSPNTGGTSPTSTTHTSSPNTGGTS
                     PTSTTHTSSPPTGGTSPTSTTHTSSPNTGGTSPTSTTHTSSPPTGGTSPTSTTHTSSP
                     PTGGTSPTSTTHTSLPPTGGTSPTSTTHTSSPPTGGTSPTSTTHTSSPPIGESSTIST
                     TDIRTSSTQMAHTTFVGKTSTISGPGTSTTSIPTSTTGSSSHFEVTRSPVMAHCQPQC
                     NWTKWLDTDFPVPGPHGGDLETYGNIKKSGERLCPWPEEITRLECRAKDYPERAMEDL
                     GQVVQCDPSVGLVCKNSDQGPTFGMCLNYEVRLLCCHVPEDCLTTKRTTLSSTQSTTV
                     TSSTPGTTSMPQTMTTIVQTDSTTSTSQTSSPITGRASTIHTTQTTSTSTGEAWTSSV
                     QIASTTSTTHTSSPNTGRVSTTHRTHSSSPPTGGTSPTHRTHTSSPPTGGTSPTSTTH
                     ISSPPTGGTSPTSTTHTSSPNTGRVNTTHTTHTSSPPIGENSTTSTSQTSSPITGRAS
                     TIHTTQTTSTSTGEAWTSSVQIASTTSTTHTSSPNTGRVSTTHRTHTSSPPIGGTSPT
                     PTTHTSSPPTGGTSPTSTTHTSSPPIGGTSPTSTTHTSSPPTGGTSPTSTTHTSSPPT
                     GGTSPTHRTHTSSPPTGGTSPTSTTHTSSPPTGGTSPTSRTHTSSPPTGGTSPTSTTH
                     TSSPPTGGTSPTSTTHTSSPPTGGTSPTHRTHTSSPPTGGTSPTSTTHTSSPNTGRVN
                     TTHTTHTSSPPIGESSTISTTDIRTSSTQMAHTTFVGKTSTISGPGTSTTSIPTSTTG
                     SSSHFEVTRSPVTAHCQPQCNWTKWLDTDFPVPGPHGGDLETYGNIKKSGERLCPWPE
                     EITRLECRAKDYPERAMEDLGQVVQCDPRVGLVCKNSDQGPTFGMCLNYEVRLLCCHI
                     PEDCLRTDRTPVTSHKTSFPVVSSSSVSTSSSTSPRVHSTTRCFCTMSGQLYPLGTII
                     YNQTDLDGHCYYAMCSHDCQVVKGVSQDCPSTMPPRTPTLSTSTAPPVTERDWCNVFP
                     PRLKGETWPMPNCSQATCEGNNVVSLSPRQCPEVKEPSCANGYPPLKVDDQDGCCQHY
                     QCQCVCSGWGDPHYITFDGTYYTFLDNCTYVLVQQIVPVFGDFRVLIDNYYCDLGDSV
                     SCPQSIIVEYHQDRVVLTRRPVHGVMTNQIIFNNKVVSPGFQQNGIIISRVGIKMYVT
                     IQEIGVQVMFSGLIFSVEVPFNLFANNTEGQCGTCTNDKKDECRLPGGSIASSCSEMS
                     LHWKVPNQPSCQGPPPTPTSMVPRSTPTPCSPSPLCQLILSDVFKLCHDIIPPLQFYE
                     GCLFDYCHMLDLEVVCSGLELYASLCAAQGVCIPWRSHTNNTCPFTCPENQVYQPCGP
                     SNPHYCYRNDDISLSLAIQKAGPKSEGCFCPDDMTLFSSNDSICVPSCQWCLGPHGEP
                     VEPGHTISINCQDCICKEGTLTCQEKLCPQPTCPEPGFVPVSVALEAGQCCSQFSCVC
                     NSSHCPPPLHCPESSSLIVTYEEGTCCPSQNCSSQKGCDVNGTLYQPGDVVSSSLCER
                     CLCEVSSNAFSDGFVVNCEIELCNTQCPKGFEYQTTPGHCCGHCIPKTCPFKNSNNST
                     SLYKPGEFWPEPGNPCVTHKCEKFQDVLTVVTMKIECPKINCPQDQAQLREDGCCYDC
                     LVPQQKCTVHQRQQIIRQQNCSSEGPVSLSYCQGNCGDSTSMYSLEANTVEHTCECCQ
                     ELQTSQRSVTLHCDDGSSRTFSYTQVEKCGCLGQRCHAPGDTSHSESSEQEFKSKESE
                     EPGQQSASRVSEDTLGPFQ"
     exon            113..187
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            188..247
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            248..509
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            510..624
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            625..715
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            716..825
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            826..1039
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1040..1165
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1166..1280
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1281..1419
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1420..1530
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1531..1600
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1601..1738
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1739..1903
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1904..1998
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1999..2125
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            2126..2381
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            2382..2434
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            2435..2535
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            2536..2687
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            2688..2826
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            2827..2940
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            2941..3120
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            3121..3360
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            3361..3517
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            3518..3646
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            3647..3803
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            3804..3847
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            3848..4033
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            4034..7252
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            7253..8686
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            8687..8880
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            8881..9055
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            9056..9306
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            9307..9490
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            9491..9692
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            9693..9871
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            9872..9962
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            9963..10063
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            10064..10095
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            10096..10258
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            10259..10363
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            10364..10401
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            10402..10524
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            10525..10623
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            10624..10743
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            10744..10801
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            10802..10910
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
     exon            10911..11534
                     /gene="Muc5ac"
                     /gene_synonym="AABR07006032.1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agaggctgcc agtggggaca tttccccatg ctccatagca tgggtgttgg ccggagaaag
       61 ttggccccat tctgggtcct agccttggct ctgaccttca accaacacac aggtcaggcc
      121 cttgaggaca ctcggaaatc tcaccttgaa cactactctg acttatctca acctcaaggg
      181 catgttggta ccccactcaa tagagtgacc atcatcccac ctctgaagac cattcctgtg
      241 gtacgagcct tcaacccagc acataccagg cgggtgtgca gcacatgggg caacttccac
      301 tacaagacct ttgatggaca ggtcttctac ttccctggtc tgtgcaacta tgtgttctcg
      361 gaacactgtg gggctgccta cgaggacttc aatatccagc tacgccgtgg cctggagtct
      421 aattccacca ctctgagcag ggtcatcatg aagcttgatg gcctagttgt tgagctgacc
      481 aagagctccg tcttagtcaa taaccacccg gtccagctgc ccttcagcca gtctggggtc
      541 ctcattgagc tcagcaatgg ctacctgaag gtggtggcca ggctggggct ggtcttcatg
      601 tggaatgatg atgacagtct tctgctggag ttggacacca aatatgccaa caagacttgt
      661 ggtctctgtg gagacttcaa tggcagtcca gaatccagcg agtttctctc ccacaatgtt
      721 aggctgacac cccttgagtt tgggaacttt cagaagatgg acggccccac agagcagtgc
      781 caggaccccc tccccgtgcc ccagaagaac tgctccatca gatctagcat ctgtgaagag
      841 atcctgaaag gtcagctgtt ctcaaactgt gcggccctgg tggacatcag cagctacctg
      901 gaggcttgcc agcaggacct ctgtctctgt gagagctctg acccgtctaa ctgcatctgc
      961 cataccctgg ctgagtactc tcggcagtgt gcacatgccg gaggacagcc tcagaactgg
     1021 cggggtccca acctctgccc tcagacctgt ctcctcaaca tggagtacca ggaatgtggc
     1081 tcaccctgtg tagacacctg ctccaacccc cagcattccc aggtctgtga ggaccactgt
     1141 gttgctggct gcttctgtcc tgagggtatg gtgcttgatg acagtaacca gacgggctgt
     1201 gtccctgtgt cccagtgtgc ttgcctgtac aatgggacat tgtatgcacc gggtaccagc
     1261 tattctactg actgcaccaa cacgtgctct ggaggtcagt ggagctgcca ggaagtccca
     1321 tgctctggta cctgctcagt aatgggaggc tcccacatct ccacgtttga tgaaaggcag
     1381 tacacagtac atggggactg cagctacgtg ctgtgcaagc cctatgacag caatgccttc
     1441 actgtgctgg ctgagctgcg gaagtgtgga ttgactgaga gcgagacttg tctgaagact
     1501 gtgacgttga acctgggtgg ggggaagacg gtgatcacag tgaaagccac tggagaggtc
     1561 tttgtgaacc agatctatac ccagctgccg gtatccacag ccaacgctac cttcttccgg
     1621 ccttcaacct tcttcatcat tggccagacc aacctgggtt tgcagcttga gatccagctg
     1681 catcccatta tgcaggtgtc cgtgcgcata gcacccgagt tcagggggct aacctccggg
     1741 ctctgtggta atttcaacag tatgcaggcc gatgacttcc agaccatcag tggggttgtg
     1801 gagggcacag cagctgcttt cttcaacacc ttcaagactc aggcggcttg tcccaatgtt
     1861 aagaatatct ttgaggaccc ctgctcgctc agcgtggaga atgaaaagta tgcgcagcac
     1921 tggtgttctc agctgactga tgccaatggc ccattttccc agtgccatgc cacagtgaac
     1981 cccagcacct tcttctcgaa ctgcatgttt gacacgtgca actgtgagaa gagtgaggac
     2041 tgcctgtgtg ccgccctgtc ctcctatgtg cgtgcctgtg ctgccaaagg cgtgctgctc
     2101 agtgactgga gggagggcat atgcgaaaaa cctacaatta cctgtcccaa gtcgatgacc
     2161 tatcaatacc atatcagcac ctgccagccc acctgccggt ctctgagtga ggaagatgtc
     2221 acctgccatg tcaacttcat ccctgtggat ggctgcacct gccccaaagg caccttcttg
     2281 gatgattcgg gcaaatgtgt acaggccact agctgtcctt gctattacaa gggatcccca
     2341 gttcccaatg gcgagtctgt gcatgacaac ggggccattt gcacctgcac ccaaggagca
     2401 ctaacttgta ttggaggtcc tgtcctgact ccagtgtgtg atgcccccat gatctatttt
     2461 gactgtcgta atgccacacc tggtgacact ggagctggat gtcagaagag ctgtcacacc
     2521 ctagatatga cctgctacag ctccgagtgt gtgcctggct gtgtgtgccc gaatgggctg
     2581 gtggcagatg gcaatggaag ctgtgttgtt gctgaggact gcccttgtgt gcacaatgag
     2641 gccacctaca ggcctgggga gaccatccaa gtgggctgca acaactgcac ctgtgagaac
     2701 aggatgtggc agtgcacaga caagccttgc ctggccacct gtgctgtgta cggggatggg
     2761 cactatatca cttttgatgg gcagcgctac agtttcagtg gggactgcga gtacacactg
     2821 ctgcaggaca actgtggtgg gaacggcagc tcccaggatg cctttcgtgt tgtcactgag
     2881 aacattccct gtggtactac agggactacg tgctcaaagg gaatcaagat cttcctgggg
     2941 agctatgagc tgaaattgag tgacagcaag atggaggtgg tccagaaggg tgtggggcag
     3001 gagcccccct acttcgtcca tcagatgggc aactacctgg tggtggaaac cgacattggc
     3061 ctggtgcttt tgtgggacaa gaagaccagc atctttctca gactcagccc tgagttcaag
     3121 ggcaaggtct gtggcctgtg tgggaacttt gatgacaatg ccatcaatga cttcaccaca
     3181 cgcagccagt ctgtggttag tgacatgctg gagtttggaa atagctggaa gttgtctccg
     3241 tcctgcccgg atgcctcagt gtccaaggat ccctgcactg ccaaccctta ccgcaagtcc
     3301 tgggcccaaa agcaatgcag catcatcaac agcgcaacct tctctgcctg ccatgctcat
     3361 gtggaaccgg ccaagtacta tgaagcctgt gtgaatgacg cctgtgcctg tgactcaggg
     3421 ggtgactgcg agtgcttctg cactgctgtg gctgcctatg cccaggcctg ccacgaagtg
     3481 ggagtgtgtg tgtcctggag gactccagac atctgtccac tgttctgtga ctactacaac
     3541 ccagagggtc agtgtgagtg gcactaccag ccgtgtgggg ccccctgcat gcgtacctgc
     3601 cagaacccta ctggacagtg cctacaagat ctccgtggcc tggaaggctg ctaccccaag
     3661 tgcccaccaa cagcccccat ctttgatgag ggcactatgc agtgtgtatc caactgtaca
     3721 gtcagcccct caccctgccg tgtcaatgga aagttgtacc gaccaggtac accgatacct
     3781 tcagatgaaa actgttattc ctgtgtttgt acggagagtg gtgtgaactg tacccatgat
     3841 gctggtgcct gtgtttgtac ctacaatggg caacggtacc atcctgggga caccatctac
     3901 cacacgacag atggcatggg aggttgtatc tctgcacact gcagggacaa tggcaccatt
     3961 gagaggatcg ttgatacctg cagttccacc agccccccac cccccaccac tttctccttc
     4021 tccacaacgc tggtcatgac ctcaatgcaa ccctccagca cacattccag ccctaccccg
     4081 agcgtagtgt acccggggtc cccaagcaag gccgtgttga cagccagcag cgtatcgtct
     4141 gtgaagaccc ctgaaacaac ctctgtcttg actacatcta cttcagcctc caccttaacc
     4201 atgccagctt gccaagagga gtgcctctgg tctccctgga tggatatcag ccgtcctgga
     4261 cgtggcattg acagtggtga ctttgacact ctggagaacc tccatgccca tggctaccag
     4321 atctgcccag tgccaaaagc agtggagtgc cgtgctgagg ataaccctgg ggtgcctttc
     4381 catgcactac agcagcatgt ggagtgtagc acaactgtag ggctgatctg ttacaacagt
     4441 gaccaggtgt cagggctctg tgacaactac cagatcaaaa tccaatgctg tacccccatc
     4501 aactgtccaa cctccactgg tcctacccag accacccatt tgatagtctc caggacaagt
     4561 acgatggagg acacaacctc ctcagtccct gtcacctcaa ctgagcacac atatagcaca
     4621 gttgcctcaa gtccttctac ccatacccca ggtccttctc cctcttcctc cgtaccttct
     4681 tcatcagctc cagctcgatc gactcctact ccagtcagtt ctaccactgt taaaacaact
     4741 ctgcccacca caagcccaat gccagagcca acttcagcca catcgtctgt gtccatctca
     4801 accttagggt ccaccctagc ctcccctgag ataactcatg ggtgcagaaa ggagctttgc
     4861 aattggactg attggataga tggcagctac cctgagcctg gcagaagcag tggtgatttt
     4921 gacacctttg taaacctgag agccaaaggg tacaagttct gtgagaagcc atggaatgtt
     4981 gagtgcaggg ctcagttctt tcccaacaca ccactgcaag agctgggaca ggatgtgacc
     5041 tgtagccgag aagtgggttt gatctgtttg aacaagaacc agctgccacc catttgctac
     5101 aactatgaga tccggataga atgctgcacc atagtaaaca tctgttccac aacttcagct
     5161 accacacagc ccacctcaca tggagtcagc ataaaaacaa agacgaactg gatcacaaac
     5221 acatattcct tttccaccga gaataccagt ggtcactcaa cagtcataaa caccaagacc
     5281 tgggtcacag gtagtacaca cacaacccct caaccaggaa caaggccgac acccagcaca
     5341 gtgtccaccc aggacaccag caccagctct gtgcagacag acagcaccac ctcctcatcc
     5401 cacaccagct caccaaatac aggaagagtc agcaccaccc acacaaccca caccagctca
     5461 ccacctacag gaggaaccag ccccacctcc acaacccaca ccagctcacc acctacagga
     5521 ggaaccagcc ccacctccac aacccacacc agctcaccac ctacaggagg aaccagcccc
     5581 acctccacaa cccacaccag ctcaccacct acaggaggaa ccagccccac ctccacaacc
     5641 cacaccagct caccacctac aggaggaacc agccccacct ccacaaccca caccagctca
     5701 ccacctacag gaggaaccag ccccacttcc acaacccaca ccagctcacc aaatacagga
     5761 agagtcagca ccacccacac aacccacacc agctcaccac ctacaggagg aaccagcccc
     5821 acttccacaa cccacaccag ctcaccaaat acaggaggaa ccagccccac ctccacaacc
     5881 cacaccagct caccaaatac aggaggaacc agccccacct ccacaaccca caccagctca
     5941 ccacctacag gaggaaccag ccccacctcc acaacccaca ccagctcacc aaatacagga
     6001 ggaaccagcc ccacctccac aacccacacc agctcaccac ctacaggagg aaccagcccc
     6061 acttccacaa cccacaccag ctcaccacct acaggaggaa ccagccccac ttccacaacc
     6121 cacaccagct taccacctac aggaggaacc agccccacct ccacaaccca caccagctca
     6181 ccacctacag gaggaaccag ccccacctcc acaacccaca ccagctcacc acccatagga
     6241 gaaagcagca ccatttctac cacggatatc agaaccagct ctacgcagat ggcccacaca
     6301 acattcgtgg ggaaaaccag cacgatctct ggtcctggaa ccagcaccac ctccattcct
     6361 accagtacca cgggttccag ctctcatttt gaggtgactc gttccccagt gatggcccac
     6421 tgccagccac agtgcaactg gaccaagtgg cttgacactg acttcccagt tcctggtcca
     6481 catggagggg acctggaaac ctatggcaac atcaagaaga gcggagagag actctgtcct
     6541 tggccagagg agatcacacg gttggaatgt agggctaagg actaccctga gagagcgatg
     6601 gaggatctgg gtcaggtggt gcagtgtgac cccagcgtgg gcctggtgtg caagaacagc
     6661 gaccagggac ccacctttgg gatgtgcctc aactatgagg tgcgactgct ttgctgtcac
     6721 gttcccgaag actgcctcac caccaaacgt acaactcttt ccagcaccca aagtacgact
     6781 gtcaccagct caacacctgg cactacttcc atgccccaaa ctatgacaac cattgtacag
     6841 acagacagta ccacctccac atctcaaaca agctcaccca ttacagggag agccagcacc
     6901 atccacacaa ctcaaaccac ctcaacatca acaggagaag cctggaccag ctctgtgcag
     6961 atagccagca ctacctccac aacccacacc agctcaccaa atacaggaag agtcagcacc
     7021 acccacagaa cccacagcag ctcaccacct acaggaggaa ccagccccac ccacagaact
     7081 cacaccagct caccacctac aggaggaacc agccccacct ccacaaccca catcagctca
     7141 ccacctacag gaggaaccag ccccacctcc acaacccaca ccagctcacc aaatacagga
     7201 agggtcaaca ccacccacac aacccacacc agctcaccac ccataggaga aaacagtacc
     7261 acctccacat ctcaaacaag ctcacccatt acagggagag ccagcaccat ccacacaact
     7321 caaaccacct caacatcaac aggagaagcc tggaccagct ctgtgcagat agccagcacc
     7381 acctccacaa cccacaccag ctcaccaaat acaggaagag tcagcaccac ccacagaacc
     7441 cacaccagct caccacccat aggaggaacc agccccactc ccacaaccca caccagctca
     7501 ccacctacag gaggaaccag ccccacctcc acaacccaca ccagctcacc acccatagga
     7561 ggaaccagcc ccacttccac aacccacacc agctcaccac ctacaggagg aaccagcccc
     7621 acctccacaa cccacaccag ctcaccacct acaggaggaa ccagccccac ccacagaact
     7681 cacaccagct caccacctac aggaggaacc agccccacct ccacaaccca caccagctca
     7741 ccacctacag gaggaaccag ccccacctcc agaacccaca ccagctcacc acctacagga
     7801 ggaaccagcc ccacctccac aacccacacc agctcaccac ctacaggagg aaccagcccc
     7861 acttccacaa cccacaccag ctcaccacct acaggaggaa ccagccccac ccacagaact
     7921 cacaccagct caccacctac aggaggaacc agccccacct ccacaaccca caccagctca
     7981 ccaaatacag gaagggtcaa caccacccac acaacccaca ccagctcacc acccatagga
     8041 gaaagcagca ccatttctac cacggatatc agaaccagct ctacgcagat ggcccacaca
     8101 acattcgtgg ggaaaaccag cacgatctct ggtcctggaa ccagcaccac ctccattcct
     8161 accagcacca cgggttccag ctctcatttt gaggtgactc gttccccagt gacggcccac
     8221 tgccagccac agtgcaactg gaccaagtgg cttgacactg acttcccagt tcctggtcca
     8281 catggagggg acctggaaac ctatggcaac atcaagaaga gcggagagag actctgtcct
     8341 tggccagagg agatcacacg gttggaatgc agggctaagg actaccctga gagagcgatg
     8401 gaggatctgg gtcaggtggt gcagtgtgac cccagagtgg gcctggtgtg caagaacagc
     8461 gaccagggac ccacctttgg gatgtgcctc aactatgagg tgcgactgct ttgctgtcac
     8521 attcctgaag actgcctcag gaccgaccgg actcctgtga catcccacaa gacctcattt
     8581 ccagttgtgt catcatcatc tgtgtccaca tcctcatcta ccagtcctag agttcactct
     8641 accacccgtt gtttctgcac catgtcaggc caattatacc ctttgggaac catcatctac
     8701 aaccagacag accttgacgg ccactgttac tatgcgatgt gcagccatga ttgtcaggtg
     8761 gtcaaagggg ttagtcagga ctgcccctcc accatgccac cccgtacacc aactctatcc
     8821 acatctaccg ccccacctgt cactgagcgg gattggtgca atgtgtttcc tccaagactg
     8881 aaaggggaga cctggcccat gcctaattgt tcccaagcca catgtgaggg caacaatgtt
     8941 gtctctttga gcccacgcca gtgtccagag gtgaaggagc catcttgtgc caatggctac
     9001 ccacctctga aggtggatga ccaggacggt tgctgccagc actaccagtg ccagtgtgtt
     9061 tgcagcggct ggggtgaccc ccactacatc acatttgacg gcacctacta cacttttctg
     9121 gacaattgca catacgtgct ggtgcagcag attgtgcctg tgtttggaga cttccgtgtg
     9181 ctcattgaca actactactg tgacctggga gacagtgttt cctgcccaca gtccatcatt
     9241 gtcgagtacc accaggaccg tgtggtgctg acccgcaggc cggttcacgg ggtcatgacc
     9301 aaccagatca tcttcaacaa caaggtcgtg agtcctggct tccagcagaa tggcattatc
     9361 atctcccgtg tgggtatcaa gatgtatgtc accatccaag agattggtgt ccaggtcatg
     9421 ttttcaggcc tcatcttctc agttgaggtg cccttcaact tgtttgccaa caacacggag
     9481 ggccaatgcg gcacttgtac caatgacaaa aaggatgaat gccgcctgcc tggaggttcc
     9541 atagcctcct cttgttctga gatgtccctc cactggaagg tgcccaacca gccttcctgc
     9601 caagggcctc caccaacacc aacttcaatg gtacccaggt ctacacctac tccgtgctca
     9661 ccatcgccac tctgtcagct catcctaagc gacgtcttca agctctgcca tgacatcatc
     9721 cccccgctgc agttctatga aggctgctta tttgactact gccacatgtt ggacttggag
     9781 gtggtgtgct caggcctgga gctctatgca tcactatgtg cagcccaagg cgtgtgcatc
     9841 ccctggagaa gccataccaa caacacctgt ccattcacgt gccctgaaaa ccaagtatac
     9901 cagccttgtg gtccttccaa ccctcactac tgctacagga atgatgatat cagcctaagc
     9961 ttggccattc aaaaggctgg tcctaagtca gagggctgct tctgtccaga tgacatgaca
    10021 cttttcagtt ctaacgactc aatctgcgtg ccttcctgcc aatggtgtct ggggcctcat
    10081 ggggaacctg tggagccggg ccacaccatc agcatcaact gccaggactg catctgtaag
    10141 gagggcacgc tgacctgcca agagaagtta tgcccccagc ccacctgtcc agaacccggc
    10201 tttgtgccgg tgtctgtagc cctggaggct ggccagtgtt gttcccagtt cagctgtgtc
    10261 tgcaactcca gccactgccc tcctcctttg cactgcccgg agagttctag cctgatagtc
    10321 acatatgagg agggaacttg ctgcccaagc cagaactgca gcagtcagaa gggctgtgac
    10381 gtcaacggga ctctgtacca gcctggtgac gtggtctcct ccagcctatg tgaaagatgc
    10441 ctgtgtgaag tttccagcaa tgccttttcc gatggctttg tagtcaactg tgagattgag
    10501 ctctgtaaca cccaatgtcc taagggcttt gagtaccaga cgactccagg gcactgctgt
    10561 ggccactgca taccgaagac ctgccccttt aaaaacagca ataactccac ttccctctac
    10621 aagcctggtg agttctggcc agaacctggg aacccgtgtg tgactcataa gtgtgagaaa
    10681 ttccaagatg tactcacggt ggtgacaatg aagatagagt gccccaagat caactgtcca
    10741 caagaccagg ctcagctgag agaagacgga tgctgctatg actgtctcgt accccagcag
    10801 aaatgtacag tgcaccaaag acagcagatc atccgtcagc aaaactgcag ctctgagggc
    10861 ccagtgagcc tctcctactg ccagggcaat tgtggggaca gcacctccat gtactctctg
    10921 gaggccaaca cggtggaaca cacgtgtgag tgttgccagg agctgcagac ctcgcagagg
    10981 agtgtgactc tgcactgtga tgacggctcc agtcggacct tcagctacac ccaggttgag
    11041 aagtgtggct gcctgggcca gcggtgccat gctccaggtg acacaagcca ctcagagtcc
    11101 tcagaacaag agttcaagtc caaggaaagt gaggaacctg gccagcagtc agcatccagg
    11161 gtcagcgagg acacccttgg gcctttccag taaaccaagc agcactgccg tcccaaccaa
    11221 gaagtcctcc tgaggccagc aggacgtgta ctttagtcca agtggcttga attctaccta
    11281 cctgctgctt cctcttcaag agggaccccg gatgttcttg gaggtgggag aggcccctct
    11341 ccactgatta ggagcgtgat ggccacgggc tccttttgaa agaacttcat tatcaccaaa
    11401 gggtcccagg agtgacagtc acttggatgc aggtatcagc ctcgctctca cctcagccct
    11461 gctcctgtgt cccccatccc caggaaatga ccaatatgtt ttataaatat actcaagagc
    11521 atttgtggat tctc
//
