LOCUS       NM_001401397            2306 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus mucin 20, cell surface associated (Muc20),
            transcript variant 1, mRNA.
ACCESSION   NM_001401397 XM_006248449
VERSION     NM_001401397.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2306)
  AUTHORS   Qin,Y.H., Lei,F.Y., Hu,P., Pei,J., Feng,Z.B. and Pang,Y.S.
  TITLE     Effect of all-trans retinoic acid on renal expressions of matrix
            metalloproteinase-2, matrix metalloproteinase-9 and tissue
            inhibitor of metalloproteinase-1 in rats with glomerulosclerosis
  JOURNAL   Pediatr Nephrol 24 (8), 1477-1486 (2009)
   PUBMED   19357873
REFERENCE   2  (bases 1 to 2306)
  AUTHORS   Li,G., Zhang,H., Lv,J., Hou,P. and Wang,H.
  TITLE     Tandem repeats polymorphism of MUC20 is an independent factor for
            the progression of immunoglobulin A nephropathy
  JOURNAL   Am J Nephrol 26 (1), 43-49 (2006)
   PUBMED   16508246
REFERENCE   3  (bases 1 to 2306)
  AUTHORS   Higuchi,T., Orita,T., Katsuya,K., Yamasaki,Y., Akiyama,K., Li,H.,
            Yamamoto,T., Saito,Y. and Nakamura,M.
  TITLE     MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras
            pathway by binding to a multifunctional docking site of met
  JOURNAL   Mol Cell Biol 24 (17), 7456-7468 (2004)
   PUBMED   15314156
REFERENCE   4  (bases 1 to 2306)
  AUTHORS   Higuchi,T., Orita,T., Nakanishi,S., Katsuya,K., Watanabe,H.,
            Yamasaki,Y., Waga,I., Nanayama,T., Yamamoto,Y., Munger,W.,
            Sun,H.W., Falk,R.J., Jennette,J.C., Alcorta,D.A., Li,H.,
            Yamamoto,T., Saito,Y. and Nakamura,M.
  TITLE     Molecular cloning, genomic structure, and expression analysis of
            MUC20, a novel mucin protein, up-regulated in injured kidney
  JOURNAL   J Biol Chem 279 (3), 1968-1979 (2004)
   PUBMED   14565953
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000011.1.
            
            On Feb 10, 2022 this sequence version replaced XM_006248449.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN06680412,
                              SAMN06680413 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-110               JAXUCZ010000011.1  81492891-81493000
            111-1871            JAXUCZ010000011.1  81495729-81497489
            1872-1963           JAXUCZ010000011.1  81502963-81503054
            1964-2306           JAXUCZ010000011.1  81506229-81506571
FEATURES             Location/Qualifiers
     source          1..2306
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q22"
     gene            1..2306
                     /gene="Muc20"
                     /note="mucin 20, cell surface associated"
                     /db_xref="GeneID:303886"
                     /db_xref="RGD:1304865"
     exon            1..110
                     /gene="Muc20"
                     /inference="alignment:Splign:2.1.0"
     CDS             32..2032
                     /gene="Muc20"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; mucin-20"
                     /codon_start=1
                     /product="mucin-20 isoform 1 precursor"
                     /protein_id="NP_001388326.1"
                     /db_xref="GeneID:303886"
                     /db_xref="RGD:1304865"
                     /translation="MMSSVWGLAVPLLVFYWKVGVSVSSPGLGISRSIPLVTNNSIEV
                     PTFPQRDRPSSERAFQTTNLTQYVPLDTKTLGTETAPNTLIATSANSELNSRDTQTTS
                     FVTKTRKTHPTTLAAPFLETQTISPNVSTLNIQTTSPTASSLDSLTTFPAPPSSLTTF
                     PAPSSSSLTTSPPPPPSLTTSPASSSSLTTSSAPSSSLTTSPPPPPSLTTSPAPSSPS
                     TSPAPSSLTTFSAPPFLGNQTVSPVELTLKTQTIPSVTETRILSKRIPSNFMVVHTIP
                     TGTLAPSDSPRAGMTTVKAGTVSDPIEAVLGTLCTDDSSEETRKITIDLLTLAHPSMG
                     VEQLSSESSSSSDSSAGVLSSSQALGPDSTTPAKDSVAFSISHIKLTTCITEIETTIT
                     ISGTPDASRSPAEAMTALSASEMLTLPPSTEAKPVVPKTTSSSGILSTATTLALATTL
                     EGTLPASGITESEIAVAQTPTSSGTSATGGTQVTVRRNPLEDTSALSSETQSHTEVFG
                     TITVPTVAGSTVGEATSLVSSTALDSSLSAVVTTKGSASSETLTTDNTTNSSFLTGSR
                     PPSLIYSTTASTSERTNVTLTKTTASPKTPMNPAPTAWTRKTTEHDPGINGGFLLVRL
                     TVASPKDLTEHVTREKLMHQLRRELHTHMPLVQVSLLSIRRS"
     exon            111..1871
                     /gene="Muc20"
                     /inference="alignment:Splign:2.1.0"
     exon            1872..1963
                     /gene="Muc20"
                     /inference="alignment:Splign:2.1.0"
     exon            1964..2306
                     /gene="Muc20"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cagcaggcag gtctgacagg cagcggtggt catgatgagc tctgtctggg gcctggctgt
       61 accgctcctt gtcttctact ggaaggttgg agtcagtgtg agctctccag gtctcggcat
      121 tagcagatcc attcctttgg tgacaaacaa cagcatagaa gtgcccacct tccctcaaag
      181 ggacagaccc agctcagagc gagctttcca gaccaccaac ctgactcagt atgttcctct
      241 agacacgaaa actctaggca ctgaaactgc tcctaacacc ttaattgcaa ccagtgccaa
      301 ttcagaactc aattccaggg acacccagac cacctctttt gtaacaaaga ccaggaagac
      361 acatcctact actcttgcag caccattcct tgagacccag accatctctc ctaatgtgtc
      421 aaccctaaat attcagacca cttccccaac agcatcgtcc ctggattccc tgaccacttt
      481 ccctgcacca ccatcatccc tgaccacttt ccctgcacca tcatcatcat ccctgaccac
      541 ttcccctcca ccaccaccat ccctgaccac ttcccctgca tcatcatcat ccctgaccac
      601 ttcctctgca ccatcatcat ccctgaccac ttcccctcca ccaccaccat ccctgaccac
      661 ttcccctgca ccatcatctc catccacttc tcctgcacca tcatccctga ccactttctc
      721 tgcaccacca ttcctgggga accagactgt ctcgcctgtt gaattgaccc taaagaccca
      781 gaccattccc tctgtaacag agaccagaat tctttcgaaa agaatacctt ccaacttcat
      841 ggttgtgcac accatcccta cagggacatt ggcaccaagt gacagcccca gagctgggat
      901 gaccactgtc aaagctggca cagtgagtga ccccatagaa gccgtccttg gcaccctttg
      961 tactgatgac agctctgaag agacaaggaa gatcacaatt gacctcctga ctttggcaca
     1021 cccctccatg ggagtggagc agctgtcttc agagagcagc tcctcctctg acagctcagc
     1081 tggggtcctc agcagctctc aggccctggg acccgacagt acaactccag ccaaggactc
     1141 agttgccttc agcatctccc atattaagct caccacctgc atcacggaaa tagaaacaac
     1201 catcaccatc tctgggaccc cagacgcgag ccgcagccct gcagaagcaa tgacagcttt
     1261 atctgcttct gagatgttaa ctttgcctcc atccactgag gcaaagccag ttgtccctaa
     1321 gaccacaagc tcatctggga tcctgtcaac tgccactacc ctggcccttg ccaccaccct
     1381 tgagggtaca ctccctgcta gtggaatcac agaaagcgaa atagcagtgg cccagactcc
     1441 tacctccagt ggaacttcgg ctacaggagg aacccaggtg acagttagaa ggaacccact
     1501 ggaagacact tcagcactct ctagtgagac acaaagccac actgaggttt ttggtaccat
     1561 cacagtcccc acggttgctg gatcaacagt aggagaagca acctctcttg tgagttccac
     1621 agctctagac agcagtctct cagcagtggt caccaccaag ggctctgctt cctcagagac
     1681 tttaaccaca gacaatacaa ccaacagctc cttcctcaca gggagtcgcc ctccttcttt
     1741 aatctattcg acaacagcta gcaccagtga aagaacaaac gtcactttaa ccaagaccac
     1801 agcctcaccg aagaccccga tgaatcccgc acccactgct tggacaagga aaaccacaga
     1861 gcacgatcca ggtataaatg gaggcttcct ccttgtacgg ctgaccgtgg cctcccctaa
     1921 ggacctcact gagcacgtca ccagagagaa gctgatgcac cagctccgcc gtgaactgca
     1981 cacccatatg ccacttgtcc aagtgtcctt actgagcatc aggaggagct gaagaatgca
     2041 agttgcaacc aggcatggcc cccgtgtcag aagaagtgat ggcacctgtg gctcagatgt
     2101 taccaacaaa ccacggccat ggttctgtgc tatggactca gaaggttccc atgaagctca
     2161 gctggctgga gagccctcct ccatacctga tcacaagatg ttggtctact tatgcctgag
     2221 tgggagaggc tggcctgttt ccagtgatgg ccttcacctc ctctgactgg ttattgtgtt
     2281 tcagtaaagg gagacctgat cactca
//
