LOCUS       NM_001421297            2995 bp    mRNA    linear   ROD 09-APR-2024
DEFINITION  Rattus norvegicus mucin 13, cell surface associated (Muc13), mRNA.
ACCESSION   NM_001421297 XM_008768788
VERSION     NM_001421297.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2995)
  AUTHORS   Poon,C.E., Lecce,L., Day,M.L. and Murphy,C.R.
  TITLE     Mucin 15 is lost but mucin 13 remains in uterine luminal epithelial
            cells and the blastocyst at the time of implantation in the rat
  JOURNAL   Reprod Fertil Dev 26 (3), 421-431 (2014)
   PUBMED   23517642
  REMARK    GeneRIF: Mucin 15 is lost but mucin 13 remains in uterine luminal
            epithelial cells and the blastocyst at the time of implantation in
            the rat.
REFERENCE   2  (bases 1 to 2995)
  AUTHORS   Chang,M., Alsaigh,T., Kistler,E.B. and Schmid-Schonbein,G.W.
  TITLE     Breakdown of mucin as barrier to digestive enzymes in the ischemic
            rat small intestine
  JOURNAL   PLoS One 7 (6), e40087 (2012)
   PUBMED   22768227
  REMARK    GeneRIF: These results indicate that mucin plays an important role
            in the preservation of the mucosal barrier and that ischemia but
            not digestive enzymes disturbs mucin integrity, while digestive
            enzymes actively mediate epithelial cell disruption.
REFERENCE   3  (bases 1 to 2995)
  AUTHORS   Hasnain,S.Z., Thornton,D.J. and Grencis,R.K.
  TITLE     Changes in the mucosal barrier during acute and chronic Trichuris
            muris infection
  JOURNAL   Parasite Immunol 33 (1), 45-55 (2011)
   PUBMED   21155842
REFERENCE   4  (bases 1 to 2995)
  AUTHORS   Moehle,C., Ackermann,N., Langmann,T., Aslanidis,C., Kel,A.,
            Kel-Margoulis,O., Schmitz-Madry,A., Zahn,A., Stremmel,W. and
            Schmitz,G.
  TITLE     Aberrant intestinal expression and allelic variants of mucin genes
            associated with inflammatory bowel disease
  JOURNAL   J Mol Med (Berl) 84 (12), 1055-1066 (2006)
   PUBMED   17058067
REFERENCE   5  (bases 1 to 2995)
  AUTHORS   Williams,S.J., Wreschner,D.H., Tran,M., Eyre,H.J., Sutherland,G.R.
            and McGuckin,M.A.
  TITLE     Muc13, a novel human cell surface mucin expressed by epithelial and
            hemopoietic cells
  JOURNAL   J Biol Chem 276 (21), 18327-18336 (2001)
   PUBMED   11278439
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000011.1.
            
            On May 15, 2023 this sequence version replaced XM_008768788.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643291.31298.1,
                                           SRR26643288.45791.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-896               JAXUCZ010000011.1  80484511-80485406   c
            897-1022            JAXUCZ010000011.1  80480889-80481014   c
            1023-1129           JAXUCZ010000011.1  80479629-80479735   c
            1130-1185           JAXUCZ010000011.1  80478444-80478499   c
            1186-1352           JAXUCZ010000011.1  80476729-80476895   c
            1353-1475           JAXUCZ010000011.1  80473551-80473673   c
            1476-1596           JAXUCZ010000011.1  80472532-80472652   c
            1597-1634           JAXUCZ010000011.1  80471744-80471781   c
            1635-1719           JAXUCZ010000011.1  80469604-80469688   c
            1720-1915           JAXUCZ010000011.1  80465737-80465932   c
            1916-2995           JAXUCZ010000011.1  80462350-80463429   c
FEATURES             Location/Qualifiers
     source          1..2995
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q22"
     gene            1..2995
                     /gene="Muc13"
                     /gene_synonym="Ly64; Muc-123; MUC-13"
                     /note="mucin 13, cell surface associated"
                     /db_xref="GeneID:207126"
                     /db_xref="RGD:708547"
     exon            1..896
                     /gene="Muc13"
                     /gene_synonym="Ly64; Muc-123; MUC-13"
                     /inference="alignment:Splign:2.1.0"
     CDS             74..1915
                     /gene="Muc13"
                     /gene_synonym="Ly64; Muc-123; MUC-13"
                     /note="lymphocyte antigen 64; mucin 13, epithelial
                     transmembrane"
                     /codon_start=1
                     /product="mucin-13"
                     /protein_id="NP_001408226.1"
                     /db_xref="GeneID:207126"
                     /db_xref="RGD:708547"
                     /translation="MVTNSTNSPTTGLTQSSGGASSPTTAPTKPTISSSQTSTTAPPP
                     GGASSPTTAPTKPTTSSSQTSTTAPPPGGASSPTTAPTKPTTSSSQTSTTAPPPGGAS
                     SPTTAPTKPTGSSSQTSTTAPPPGGASSPTTAPTKPTTSSSQTSTTAPPPGGASSPTT
                     APTKPTTSSSQTSTTAPPPGGASSPTTVPTKPTGSSSQTSTAAPPPGGASSPATAPTK
                     PTGSSSQTSTTAPPPGGASSPATAPTKPTGSSSQTSGATQPPGGASSPTVTSSSSTGS
                     NDPCNSNPCKSPASCVKLYDSYFCLCLEGYYYNNSSSCVKGTTFPGEIGMSVTETADL
                     EDKNSVNYQSLHSSVVNFFENTFKKTDYGQTVILKVSKDSLMSSRSVMRAATKTVYVS
                     VVNMFGESTTEDEKSVASVIEEAVKTNSKVQSYSQQDRCDYYGCVKSGSNVCRNGLQC
                     TCKPGLERLNPQVPFCVAPTCSEPCSAEKKQLCLKKDNGAMECGCMAGYRKANGKCEE
                     CPFGYSGMDCKDQFQLILTIVGTIAGAFILILLIVFIVSMRSKNKKKSGEEQNLIEDD
                     FHNLRMRPTGFSNFGADTSIFPKVKTGVPSQTSNPYANHRSMPRPDY"
     exon            897..1022
                     /gene="Muc13"
                     /gene_synonym="Ly64; Muc-123; MUC-13"
                     /inference="alignment:Splign:2.1.0"
     exon            1023..1129
                     /gene="Muc13"
                     /gene_synonym="Ly64; Muc-123; MUC-13"
                     /inference="alignment:Splign:2.1.0"
     exon            1130..1185
                     /gene="Muc13"
                     /gene_synonym="Ly64; Muc-123; MUC-13"
                     /inference="alignment:Splign:2.1.0"
     exon            1186..1352
                     /gene="Muc13"
                     /gene_synonym="Ly64; Muc-123; MUC-13"
                     /inference="alignment:Splign:2.1.0"
     exon            1353..1475
                     /gene="Muc13"
                     /gene_synonym="Ly64; Muc-123; MUC-13"
                     /inference="alignment:Splign:2.1.0"
     exon            1476..1596
                     /gene="Muc13"
                     /gene_synonym="Ly64; Muc-123; MUC-13"
                     /inference="alignment:Splign:2.1.0"
     exon            1597..1634
                     /gene="Muc13"
                     /gene_synonym="Ly64; Muc-123; MUC-13"
                     /inference="alignment:Splign:2.1.0"
     exon            1635..1719
                     /gene="Muc13"
                     /gene_synonym="Ly64; Muc-123; MUC-13"
                     /inference="alignment:Splign:2.1.0"
     exon            1720..1915
                     /gene="Muc13"
                     /gene_synonym="Ly64; Muc-123; MUC-13"
                     /inference="alignment:Splign:2.1.0"
     exon            1916..2995
                     /gene="Muc13"
                     /gene_synonym="Ly64; Muc-123; MUC-13"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tacaattcag accaatggta attcacctca gctagctggg acaaatcagt ttcctggtgg
       61 taccagctct tccatggtga ctaacagcac taattctccc accacaggac tgactcagtc
      121 gtctggtggt gccagctctc ccaccacagc accgactaag cccaccatta gttcatctca
      181 gacctctacg acagctccgc ctcctggtgg tgccagctct cccaccacag caccgactaa
      241 gcccaccact agttcatctc agacctctac gacagctccg cctcctggtg gtgccagctc
      301 tcccaccaca gcaccgacta agcccaccac tagttcatct cagacctcta cgacagctcc
      361 gcctcctggt ggtgccagct ctcccaccac agcaccgact aagcccaccg gtagttcatc
      421 tcagacctct acgacagctc cgcctcctgg tggtgccagc tctcccacca cagcaccgac
      481 taagcccacc actagttcat ctcagacctc tacgacagct ccgcctcctg gtggtgccag
      541 ctctcccacc acagcaccga ctaagcccac cactagttca tctcagacct ctacgacagc
      601 tccgcctcct ggtggtgcca gctctcccac cacagtaccg actaagccca ccggtagttc
      661 atctcagacc tctacggcag ctccacctcc tggtggtgcc agctctcccg ccacagcacc
      721 gactaagccc accggtagtt catctcagac ctctacgaca gctccgcctc ctggtggtgc
      781 cagctctccc gccacagcac cgactaagcc caccggtagt tcatctcaga cctctggggc
      841 aactcagcct cctggtggtg ccagctctcc cacagtgact agcagcagta gcacaggttc
      901 caatgatcct tgcaactcta acccctgtaa atcacctgct tcttgtgtca agctgtatga
      961 cagctacttc tgcttgtgtt tagaaggcta ctactacaac aattcttcgt catgtgtgaa
     1021 aggaacgaca ttccctggag agattggcat gagcgtaact gaaacagctg acttggaaga
     1081 taaaaactct gtgaactatc aaagtttgca cagcagtgtt gttaattttt ttgaaaacac
     1141 gtttaagaag actgactatg gacagactgt gattcttaaa gtgagcaaag actctttaat
     1201 gtcatcaaga tctgtgatgc gtgctgctac gaagacagtc tatgtatcag tagtaaatat
     1261 gtttggagaa agcacaacgg aggatgaaaa gagtgtagct tctgtgatcg aggaggcagt
     1321 taagacgaat agcaaggtgc aaagctattc ccaacaagat cggtgtgatt attatggctg
     1381 tgtgaagagt ggcagcaatg tttgccggaa tggtttacaa tgcacgtgca aacctgggct
     1441 agagagactg aacccgcagg ttcctttttg tgttgctcca acatgttctg agccctgcag
     1501 tgcagagaag aagcagctat gcttaaagaa ggataatgga gcgatggagt gtgggtgcat
     1561 ggcaggctac cggaaggcga acgggaaatg tgaagagtgt ccttttggct acagcgggat
     1621 ggattgcaaa gaccaatttc agctgatcct caccattgtg ggaaccattg ctggagcttt
     1681 catcctcatc ttgctaattg tttttatcgt ctccatgagg tcaaagaaca aaaagaagag
     1741 tggagaagag cagaatctga ttgaggatga ctttcataac ctgcgaatga ggccaaccgg
     1801 cttctccaac ttcggagcag acaccagcat cttccccaaa gtcaaaacag gggtcccgag
     1861 tcagacctct aatccctacg caaaccaccg aagcatgcct cgccctgact actagaatga
     1921 taagaatttg gaaccttccc tagcccagct cacatggtga tcttaaggac aaggagaaat
     1981 ggacagagac aaaggtttga cctccagcgt tcctctgctc cgtttgcttc aacctgtgtg
     2041 aagaacgcag cttgctgaag atacaactat caaattaaat gcacatggac actatgagcc
     2101 tttctttgta agagttgatt ttctccagtt agtacagaac actacagcgg ggattggtgt
     2161 ggggattttc tttcctggtg ggccaacggt tagtgtttcc aatccagagg gagcaccctc
     2221 atagctcatc cctgagcagt gccactcctg agctctggac tctggctacc cttgaacagt
     2281 cagctgcctg tgatagggcc tcactccaag gagacaggca agagacagaa acatctccca
     2341 gctttctcag gaggactgtg gggacccagg taccttcaga tgagaataag gaggcttgga
     2401 ctagctctat cttctgtggg aacgttcaag tctttgacat gttagttggt aggaaaagca
     2461 gggaggaaaa acatgagcac aggtagtaga gagagaccaa ggaagctatg ctgggaggct
     2521 gagggaggga gaaggtagca ggtagcatct tctcccttga tgaagtccct cctcaggcag
     2581 caaatgggtg ctctcgggcg ccgccatcac caagacatag atcccgagaa acccataaaa
     2641 gcaggagtca gtgtgaagcc actgtgacag cacaggcatt ctgtctagga ctctgtcaga
     2701 ggggccgggt gttgtccact caatgacgct tcactgggcc tcagcctgct ccataatgga
     2761 agcttagcag tggccaccaa catgtacaca cacacacaca cacacacaca cacacacaca
     2821 cacaaccacg tgcgcacaca caggatagat acacccatca tctgtcttct taaatgttta
     2881 ttgtgccttt gtgtctgtct gatgtccggt cttcttgaag ggtattttta tttgttatta
     2941 tttgttcttg actgttcatt gtggaagcca atgatataat aaaatgtctt tggta
//
