LOCUS       NM_001399239            1618 bp    mRNA    linear   ROD 22-SEP-2024
DEFINITION  Rattus norvegicus Metaxin 1 (Mtx1), transcript variant 1, mRNA.
ACCESSION   NM_001399239 XM_006232612
VERSION     NM_001399239.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1618)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 1618)
  AUTHORS   Hohr,A.I., Straub,S.P., Warscheid,B., Becker,T. and Wiedemann,N.
  TITLE     Assembly of beta-barrel proteins in the mitochondrial outer
            membrane
  JOURNAL   Biochim Biophys Acta 1853 (1), 74-88 (2015)
   PUBMED   25305573
  REMARK    Review article
REFERENCE   3  (bases 1 to 1618)
  AUTHORS   Gilchrist,S.E. and Alcorn,J.
  TITLE     Lactation stage-dependent expression of transporters in rat whole
            mammary gland and primary mammary epithelial organoids
  JOURNAL   Fundam Clin Pharmacol 24 (2), 205-214 (2010)
   PUBMED   19702690
REFERENCE   4  (bases 1 to 1618)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   5  (bases 1 to 1618)
  AUTHORS   Da Cruz,S., Xenarios,I., Langridge,J., Vilbois,F., Parone,P.A. and
            Martinou,J.C.
  TITLE     Proteomic analysis of the mouse liver mitochondrial inner membrane
  JOURNAL   J Biol Chem 278 (42), 41566-41571 (2003)
   PUBMED   12865426
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Jan 5, 2022 this sequence version replaced XM_006232612.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC099090.1, FQ216274.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-625               JAXUCZ010000002.1  176918200-176918824 c
            626-695             JAXUCZ010000002.1  176917229-176917298 c
            696-775             JAXUCZ010000002.1  176917032-176917111 c
            776-868             JAXUCZ010000002.1  176914725-176914817 c
            869-1051            JAXUCZ010000002.1  176914422-176914604 c
            1052-1128           JAXUCZ010000002.1  176914244-176914320 c
            1129-1283           JAXUCZ010000002.1  176913634-176913788 c
            1284-1618           JAXUCZ010000002.1  176913225-176913559 c
FEATURES             Location/Qualifiers
     source          1..1618
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..1618
                     /gene="Mtx1"
                     /note="Metaxin 1"
                     /db_xref="GeneID:295241"
                     /db_xref="RGD:1559791"
     exon            1..625
                     /gene="Mtx1"
                     /inference="alignment:Splign:2.1.0"
     CDS             110..1501
                     /gene="Mtx1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     metaxin-1"
                     /codon_start=1
                     /product="metaxin-1 isoform 1"
                     /protein_id="NP_001386168.1"
                     /db_xref="GeneID:295241"
                     /db_xref="RGD:1559791"
                     /translation="MRLGGPPRNVRSGQRFERSRCSRGHVQFGKSPQRPLSRTRCPSS
                     KPCLSPAVRGYARQRHRESPKRAWTAALLPYGGRLRTSPRRSSEGQCSTSSSAAASPA
                     ARSHASLDLKLRVATQAETRGCSSWREKADAYERVLPGQRMCKMAAPMELFCWSGGWG
                     LPSVDLDSLAVLTYTRFTCAPLKVHKISNPWQSPSGTLPALRTSSGKVITEPHKIITH
                     LRKEKYNADYDLSARQGADTLAFISLLEEKLLPMLIHTFWIDAKNYVEVTRKWYAEAM
                     PFPLNFFLPGRMQRRHMERLQLLCGEHRLESEEELEKELYQEARECLTLLSHRLGSRK
                     FFFGDAPASLDAFVFSHLVLLLQAKLPSGKLQAHLRGLQNLCVYCTHILNLYFPRDAT
                     DVPPPPCQTPAGPETEEEPYRRRTQILSVLAGLAAMVGYALLSGIVSIQRASPARAPC
                     TQALDLAEEDEED"
     exon            626..695
                     /gene="Mtx1"
                     /inference="alignment:Splign:2.1.0"
     exon            696..775
                     /gene="Mtx1"
                     /inference="alignment:Splign:2.1.0"
     exon            776..868
                     /gene="Mtx1"
                     /inference="alignment:Splign:2.1.0"
     exon            869..1051
                     /gene="Mtx1"
                     /inference="alignment:Splign:2.1.0"
     exon            1052..1128
                     /gene="Mtx1"
                     /inference="alignment:Splign:2.1.0"
     exon            1129..1283
                     /gene="Mtx1"
                     /inference="alignment:Splign:2.1.0"
     exon            1284..1618
                     /gene="Mtx1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actccggccc cagccgggcc tcagctccgg cgccgccacc gcccctgttt tgtttccatg
       61 gcgacaggca gcgcgaagcc ggctccaaac ataacgcgct gtggaaaaca tgcggctcgg
      121 gggacccccc cgcaacgtcc gctccgggca gagatttgag aggtcccggt gtagtcgagg
      181 ccatgtgcag tttggcaaga gcccccaaag gccgttaagc cgcaccagat gcccctcttc
      241 caagccctgc ttgtctccgg cggttcgtgg ctatgctcgg cagaggcacc gtgaatctcc
      301 caagcgcgcc tggaccgcag ccctgctgcc ttacgggggc cgcctcagga cgagccctcg
      361 gcgctcctca gaagggcaat gctccacctc ctccagtgca gccgcttctc cagccgcgag
      421 aagccacgcc tccctagacc tcaaactccg agtggctaca caggcagaga ccaggggctg
      481 ttcctcctgg cgagagaagg cggacgctta tgagagggtg cttccgggtc agagaatgtg
      541 caagatggcg gcgcccatgg agctattctg ctggtctggg ggctggggat tgccgtcggt
      601 ggacctggat agtctggccg tgctgaccta taccagattt acatgtgctc cactgaaggt
      661 acacaagatc agcaatcctt ggcagagccc ttcagggact ctgcctgctc ttcgaaccag
      721 tagtggaaaa gtcatcacag aaccacacaa gatcatcacc caccttcgta aagagaagta
      781 taatgctgac tacgatctgt cagctcgaca aggagcagat accttagcct tcatttctct
      841 gctggaggag aaactactcc ctatgctaat ccatactttt tggatagatg ccaagaacta
      901 tgtggaagtg acccgaaagt ggtatgcaga ggctatgccc tttcccctca acttcttcct
      961 gcctggccgc atgcaacgcc ggcacatgga gcggctgcag ctactgtgtg gcgagcacag
     1021 attggagagc gaggaggaac tagaaaaaga gctgtatcag gaggctcggg agtgcctaac
     1081 ccttctctct catcgtctgg gctctcggaa gttcttcttt ggagatgccc ctgcctccct
     1141 ggacgccttt gtttttagcc atttggtcct gctgctgcag gcaaagctgc ccagtgggaa
     1201 gctgcaggcc caccttcggg ggctgcagaa cctctgtgtc tactgcaccc acatcctcaa
     1261 cctctacttt ccccgggatg caactgacgt gccaccgcct ccatgccaga caccagcagg
     1321 ccctgagacc gaggaggaac cataccggcg gcggacccag attctatctg tgttggcagg
     1381 gctggcagcc atggtgggct atgccttgct cagtggcatt gtttccatcc agcgtgcaag
     1441 ccctgctcgg gccccatgca cacaggcctt ggacttggct gaggaggatg aagaggactg
     1501 atgttcttgt tcccaggact gatttttcta ttcatgcatt ccaaatgccc ctttgtcccc
     1561 ccattgttgg agcagccaaa aatggggtgc tatcctcaga ataaaattgt ttacacta
//
