LOCUS       NM_001191558            3447 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus MTSS I-BAR domain containing 2 (Mtss2), mRNA.
ACCESSION   NM_001191558 XM_002728615
VERSION     NM_001191558.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3447)
  AUTHORS   Zheng,D., Niu,S., Yu,D., Zhan,X.H., Zeng,X., Cui,B., Chen,Y.,
            Yoon,J., Martin,S.S., Lu,X. and Zhan,X.
  TITLE     Abba promotes PDGF-mediated membrane ruffling through activation of
            the small GTPase Rac1
  JOURNAL   Biochem Biophys Res Commun 401 (4), 527-532 (2010)
   PUBMED   20875796
REFERENCE   2  (bases 1 to 3447)
  AUTHORS   Saarikangas,J., Hakanen,J., Mattila,P.K., Grumet,M., Salminen,M.
            and Lappalainen,P.
  TITLE     ABBA regulates plasma-membrane and actin dynamics to promote radial
            glia extension
  JOURNAL   J Cell Sci 121 (Pt 9), 1444-1454 (2008)
   PUBMED   18413296
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000019.1.
            
            On Jul 17, 2010 this sequence version replaced XM_002728615.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.76355.1,
                                           SRR26643429.55995.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389, SAMEA5760393
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-69                JAXUCZ010000019.1  55602593-55602661
            70-131              JAXUCZ010000019.1  55607090-55607151
            132-205             JAXUCZ010000019.1  55607246-55607319
            206-290             JAXUCZ010000019.1  55607979-55608063
            291-382             JAXUCZ010000019.1  55608165-55608256
            383-457             JAXUCZ010000019.1  55608337-55608411
            458-615             JAXUCZ010000019.1  55609579-55609736
            616-723             JAXUCZ010000019.1  55610020-55610127
            724-821             JAXUCZ010000019.1  55610848-55610945
            822-942             JAXUCZ010000019.1  55612897-55613017
            943-1017            JAXUCZ010000019.1  55619669-55619743
            1018-1194           JAXUCZ010000019.1  55620097-55620273
            1195-1360           JAXUCZ010000019.1  55620441-55620606
            1361-3447           JAXUCZ010000019.1  55620799-55622885
FEATURES             Location/Qualifiers
     source          1..3447
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19q12"
     gene            1..3447
                     /gene="Mtss2"
                     /gene_synonym="Abba-1; Mtss1l; RGD1309731"
                     /note="MTSS I-BAR domain containing 2"
                     /db_xref="GeneID:307845"
                     /db_xref="RGD:1309731"
     CDS             1..2148
                     /gene="Mtss2"
                     /gene_synonym="Abba-1; Mtss1l; RGD1309731"
                     /note="actin-bundling protein with BAIAP2 homology;
                     MTSS1-like protein; metastasis suppressor 1-like; MTSS1L,
                     I-BAR domain containing"
                     /codon_start=1
                     /product="protein MTSS 2"
                     /protein_id="NP_001178487.1"
                     /db_xref="GeneID:307845"
                     /db_xref="RGD:1309731"
                     /translation="METAEKECGALGGLFQAIVNDMKSSYPIWEDFNSKAAKLHSQLR
                     TTVLAAVAFLDAFQKVADMATNTRGATRDIGSALTRMCMRHRSIETKLRQFTNALLES
                     LINPLQERIEDWKKSANQLDKDHAKEYKRARHEIKKKSSDTLKLQKKARKGKGDLQPQ
                     LDSALQDVNDMYLLLEETEKQAVRRALIEERGRFCTFITFLQPVVNGELTMLGEITHL
                     QGIIDDLVVLTAEPHKLPPASEQVIKDLKGSDYSWSYQTPPSSPSSSSSRKSSMCSLA
                     QPATTRLSSVSSHDSGFVSQDATYSKPPSPMPSDITSQKSSSSASSEASETCQSVSEC
                     SSPTSDWTKTGPHEQPSATTLQRRKDRVEHLRDTETGPAGGGTVGSSGEEVPRTRMSP
                     ATIAAKHGEEVSPAASDLAMVLTRGLSLEHQKSSRDSLQYSSGYSTQTTTPSCSEDTI
                     PSQGSDYDCYSVNGDADSEGPPEFDKSSTIPRNSNIAQNYRRLIQTKRPASTAGLPTA
                     GLPTAMGLPSGAPPGVATIRRTPSTKPTVRRALSSAGPIPIRPPIVPVKTPTVPDSPG
                     YVGPTRAGSEECVFYTDEVASPLAPDLAKASPKRLSLPNTAWGSPSPEAASYGGAVVG
                     LAAEDDEVQQLAANRHSLVEKLGELVAGAQALGEGQFPFPTALSATPSEETPTPPPAA
                     TSDPPAEDMLVAIRRGVRLRRTVTNDRSAPRIL"
     exon            1..69
                     /gene="Mtss2"
                     /gene_synonym="Abba-1; Mtss1l; RGD1309731"
                     /inference="alignment:Splign:2.1.0"
     exon            70..131
                     /gene="Mtss2"
                     /gene_synonym="Abba-1; Mtss1l; RGD1309731"
                     /inference="alignment:Splign:2.1.0"
     exon            132..205
                     /gene="Mtss2"
                     /gene_synonym="Abba-1; Mtss1l; RGD1309731"
                     /inference="alignment:Splign:2.1.0"
     exon            206..290
                     /gene="Mtss2"
                     /gene_synonym="Abba-1; Mtss1l; RGD1309731"
                     /inference="alignment:Splign:2.1.0"
     exon            291..382
                     /gene="Mtss2"
                     /gene_synonym="Abba-1; Mtss1l; RGD1309731"
                     /inference="alignment:Splign:2.1.0"
     exon            383..457
                     /gene="Mtss2"
                     /gene_synonym="Abba-1; Mtss1l; RGD1309731"
                     /inference="alignment:Splign:2.1.0"
     exon            458..615
                     /gene="Mtss2"
                     /gene_synonym="Abba-1; Mtss1l; RGD1309731"
                     /inference="alignment:Splign:2.1.0"
     exon            616..723
                     /gene="Mtss2"
                     /gene_synonym="Abba-1; Mtss1l; RGD1309731"
                     /inference="alignment:Splign:2.1.0"
     exon            724..821
                     /gene="Mtss2"
                     /gene_synonym="Abba-1; Mtss1l; RGD1309731"
                     /inference="alignment:Splign:2.1.0"
     exon            822..942
                     /gene="Mtss2"
                     /gene_synonym="Abba-1; Mtss1l; RGD1309731"
                     /inference="alignment:Splign:2.1.0"
     exon            943..1017
                     /gene="Mtss2"
                     /gene_synonym="Abba-1; Mtss1l; RGD1309731"
                     /inference="alignment:Splign:2.1.0"
     exon            1018..1194
                     /gene="Mtss2"
                     /gene_synonym="Abba-1; Mtss1l; RGD1309731"
                     /inference="alignment:Splign:2.1.0"
     exon            1195..1360
                     /gene="Mtss2"
                     /gene_synonym="Abba-1; Mtss1l; RGD1309731"
                     /inference="alignment:Splign:2.1.0"
     exon            1361..3447
                     /gene="Mtss2"
                     /gene_synonym="Abba-1; Mtss1l; RGD1309731"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggagacgg cagagaagga gtgtggcgcc ctgggcgggc tcttccaggc catcgtcaac
       61 gacatgaaga gctcctaccc catctgggag gacttcaact ccaaggcggc gaagctgcac
      121 tcccagctga ggaccactgt gctggctgct gtggccttcc ttgatgcctt ccagaaagta
      181 gctgacatgg ccaccaacac ccgaggggcc acgcgggaca ttggctcagc actcacgcgc
      241 atgtgcatgc gccaccgcag catcgagacc aagctgcggc agttcaccaa cgcgctgctg
      301 gagagcctca tcaatccact gcaggagcgc atcgaagact ggaagaagtc agccaaccaa
      361 ctggacaagg accatgcgaa agagtataaa cgagccaggc atgaaatcaa aaagaagtca
      421 tctgacacgc tgaagctgca gaagaaagcg cgcaaaggga aaggagacct gcagccccag
      481 ctggacagcg cgctgcaaga tgtcaacgac atgtacctgc tactggagga gacggagaag
      541 caggctgtgc gccgcgcact gatcgaggaa cggggccgtt tttgcacttt tatcaccttc
      601 cttcagcccg tggtgaacgg cgaactgacc atgctgggag agatcaccca cctgcagggc
      661 atcattgacg acctggtagt gctgactgca gaaccccaca aactgcctcc cgccagtgag
      721 caggtgatca aagacctgaa gggctctgac tacagctggt cataccagac cccaccctcg
      781 tcgcccagca gctccagctc ccggaagtcc agcatgtgca gcctggcgca gccagccacc
      841 acccgcctct ccagtgtctc ctcccacgac tctggcttcg tctcccagga tgccacctac
      901 tccaagcccc cttcgcccat gccttcagac atcaccagcc agaagtcctc cagctccgcg
      961 tcctccgagg cctcagaaac ctgccagtcg gttagcgagt gcagctcccc gacctcggac
     1021 tggaccaaga ctggtcccca tgaacagccc tcagccacca ccctgcagcg gaggaaggat
     1081 cgtgtggaac atctccgtga cactgagaca ggcccagctg gtggaggcac tgtgggctcc
     1141 agtggagagg aggtaccacg aacccggatg tcccctgcca ccatagcagc caaacatggt
     1201 gaggaggtat cccctgctgc cagcgaccta gccatggtgc tgacccgtgg actgagccta
     1261 gaacaccaga agagcagccg ggactcgctg cagtactcca gtggctacag cacacagacc
     1321 accacacctt cctgctccga ggacaccatc ccctcccaag gctcagacta cgactgctac
     1381 tctgtgaacg gggatgcaga cagcgaaggt ccccctgaat tcgacaaatc gtccaccatt
     1441 cctcgaaaca gcaacattgc ccagaactac cgccgcctga tccagaccaa gcgtccagcc
     1501 tccactgcgg ggctgcccac cgcggggctg cccacagcca tggggctgcc ctcaggtgca
     1561 cctcctggtg tggccaccat ccgccgcacg ccctctacca agcccactgt gcgccgtgcc
     1621 ctgtccagtg ctggccccat ccccatccgc ccacccatcg tccctgtgaa gacacccacg
     1681 gtgcccgatt cccctggcta tgtggggccc acacgggcgg gcagtgagga gtgcgtcttc
     1741 tacacagacg aagtggcctc gcctctggct ccagacctgg ccaaagcctc cccaaagagg
     1801 ctcagccttc ctaacacagc ctggggcagc ccgtccccag aggcggctag ctacggcggg
     1861 gctgtggtcg ggctagccgc tgaggacgat gaagtgcagc aactggctgc caacaggcac
     1921 agcctggtgg agaagctcgg ggaactggtg gccggcgccc aggccctggg cgagggccag
     1981 ttccccttcc ctactgccct gtcggccacc ccttcggagg agacgcccac tccacctcct
     2041 gctgccacca gcgacccccc ggccgaagac atgctggtgg ccattcgacg cggggtccgg
     2101 ctgcgcagga ccgtcaccaa cgacaggtca gcgccccgca tcttatgatg gtgccaccca
     2161 cccctccctg tctgggcctg gcacaagcag gtggcctgat ctgtgagcag cggccagcca
     2221 ctctgagcag cggcagagcc agaagacaga ccagcgccag gagtgaggca cagccacttt
     2281 acagagagag acaaccaggc tggatcgcag catctcacgg gaagtgactt cccttacaca
     2341 cctcgccagg acagagcctg ttttatactg tccttaccta ctcaaccctc ctcttccttc
     2401 ctgcaggccc tgactcatcc aaaccccaga gcccacaacc aagggctggg cctgctacct
     2461 gggccccacc tggcccgggg tctgcgactc ttcctctggc ccggctgccc tccagggcca
     2521 tatgcccagc tctttccttg aatgctggct ccctcttctc cctgcttggg ccatgtcccg
     2581 tttcctcttg cctttgtcct gcctctccca ggctcctctc tttggaggac agggtggtca
     2641 tggaggggcc aggtacccaa tcagctgagg acatttttgt gactgggttt agggacagtc
     2701 aggcattggg aagccagact cactcgtggg aaagagaggc tggaaggagg gaatgtaggg
     2761 ccttgtctca ggggaccctc cagttcccct ccccctgtga agagtagcta gtggaggtga
     2821 ggcagggcag acagggaatg agtccagagc cccatagcag gtatttccga tgccctgttc
     2881 ttggctggat gtgctgaagc tttaactcta ggggaacctt ggggttacag tttcacccat
     2941 tgctgaagac ggtatgggag ttactctatg actataataa aatggagctg accctagaca
     3001 agagctgtgt ggggcaagcc ggtggtacag ggtgtgtgtc tgagtgcctg agagagctgt
     3061 gggagtccca tggtgggctc gtggccagag aagggtagaa tcagctcttc ccaatccagg
     3121 ggaagctact cttcttgcta gtgtctgaag tgtcggtaga ataaggctgg aaagggtagg
     3181 ccagggcctc tggccagtct ggtgtggtct gagtgagctg caggcccagc ttgaagcaag
     3241 tcttagaagg ttggttttgg ctttctgttg ccagaggcaa ccccatccca agaaaatctt
     3301 tgcgtgcagg cctagctggg gctggcatca ggggccaaag aaagagtggg tcctgcctcc
     3361 actgtgcagc ccaagtctga gcaagtcaaa gcacgttaag tgtaggccag aggagagatt
     3421 caggaggtag ggcaggcagc agactct
//
