LOCUS       NM_001005761            2247 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus myotubularin related protein 9 (Mtmr9), mRNA.
ACCESSION   NM_001005761 XM_341338
VERSION     NM_001005761.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2247)
  AUTHORS   Zou J, Zhang C, Marjanovic J, Kisseleva MV, Majerus PW and Wilson
            MP.
  TITLE     Myotubularin-related protein (MTMR) 9 determines the enzymatic
            activity, substrate specificity, and role in autophagy of MTMR8
  JOURNAL   Proc Natl Acad Sci U S A 109 (24), 9539-9544 (2012)
   PUBMED   22647598
REFERENCE   2  (bases 1 to 2247)
  AUTHORS   Hotta K, Kitamoto T, Kitamoto A, Mizusawa S, Matsuo T, Nakata Y,
            Kamohara S, Miyatake N, Kotani K, Komatsu R, Itoh N, Mineo I, Wada
            J, Yoneda M, Nakajima A, Funahashi T, Miyazaki S, Tokunaga K,
            Masuzaki H, Ueno T, Hamaguchi K, Tanaka K, Yamada K, Hanafusa T,
            Oikawa S, Yoshimatsu H, Sakata T, Matsuzawa Y, Nakao K and Sekine
            A.
  TITLE     Association of variations in the FTO, SCG3 and MTMR9 genes with
            metabolic syndrome in a Japanese population
  JOURNAL   J Hum Genet 56 (9), 647-651 (2011)
   PUBMED   21796137
REFERENCE   3  (bases 1 to 2247)
  AUTHORS   Lorenzo O, Urbe S and Clague MJ.
  TITLE     Systematic analysis of myotubularins: heteromeric interactions,
            subcellular localisation and endosome related functions
  JOURNAL   J Cell Sci 119 (Pt 14), 2953-2959 (2006)
   PUBMED   16787938
REFERENCE   4  (bases 1 to 2247)
  AUTHORS   Mochizuki Y and Majerus PW.
  TITLE     Characterization of myotubularin-related protein 7 and its binding
            partner, myotubularin-related protein 9
  JOURNAL   Proc Natl Acad Sci U S A 100 (17), 9768-9773 (2003)
   PUBMED   12890864
REFERENCE   5  (bases 1 to 2247)
  AUTHORS   Di Giaimo R, Riccio M, Santi S, Galeotti C, Ambrosetti DC and Melli
            M.
  TITLE     New insights into the molecular basis of progressive myoclonus
            epilepsy: a multiprotein complex with cystatin B
  JOURNAL   Hum Mol Genet 11 (23), 2941-2950 (2002)
   PUBMED   12393805
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC083644.1.
            
            On Oct 15, 2004 this sequence version replaced XM_341338.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083644.1, AF526269.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2247
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p12"
     gene            1..2247
                     /gene="Mtmr9"
                     /note="myotubularin related protein 9"
                     /db_xref="GeneID:282584"
                     /db_xref="RGD:628840"
     exon            1..423
                     /gene="Mtmr9"
                     /inference="alignment:Splign:2.1.0"
     CDS             242..1891
                     /gene="Mtmr9"
                     /codon_start=1
                     /product="myotubularin-related protein 9"
                     /protein_id="NP_001005761.1"
                     /db_xref="GeneID:282584"
                     /db_xref="RGD:628840"
                     /translation="MEFAELIKTPRVDNVVLHRPFYPAVEGTLCLTGHHLILSSRQDN
                     TEELWLLHSNIDAIDKRFVGSLGTIIIKCKDFRIIQLDIPGMEECLNIASSIEALSTL
                     DSVTLMYPFFYRPMFEVIEDGWHSFLPEQEFEFYSSATSEWRLSYVNKEFSICPTYPP
                     TVIVPKSIDDEALRKVAAFRHGGRFPVLSYYHKKNGMVIMRSGQPLTGTNGRRCKEDE
                     KLINATLRAGKRGYLIDTRSLNVAQQARAKGGGFEQEAHYPQWRRIHKSIERYHVLQE
                     SLIKLVEACNEQTHSMDRWLGKLEASNWLTHIKEILTTACLAAQCIDREGASVLIHGT
                     EGTDSTLQVTSLAQIILEPRSRTIRGFEALIEREWLQAGHPFQQRCAQSAYCSSKQKW
                     EAPVFLLFLDCVWQILRQFPCSFEFNEHFLIMLFEHAYASQFGTFLGNSENERCKLKL
                     QQKTMSLWSWVNRPSELSKFTNPLFEANNLVIWPSVAPQSLQLWEGIFLRWSRSSKYL
                     DEAYEEMVNIIEYNKELQAKVNVLRRQLAELETEDGLRESP"
     exon            424..532
                     /gene="Mtmr9"
                     /inference="alignment:Splign:2.1.0"
     exon            533..658
                     /gene="Mtmr9"
                     /inference="alignment:Splign:2.1.0"
     exon            659..832
                     /gene="Mtmr9"
                     /inference="alignment:Splign:2.1.0"
     exon            833..1050
                     /gene="Mtmr9"
                     /inference="alignment:Splign:2.1.0"
     exon            1051..1212
                     /gene="Mtmr9"
                     /inference="alignment:Splign:2.1.0"
     exon            1213..1354
                     /gene="Mtmr9"
                     /inference="alignment:Splign:2.1.0"
     exon            1355..1575
                     /gene="Mtmr9"
                     /inference="alignment:Splign:2.1.0"
     exon            1576..1727
                     /gene="Mtmr9"
                     /inference="alignment:Splign:2.1.0"
     exon            1728..2217
                     /gene="Mtmr9"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgccggtcag gggccggtgg cagcagaaag tgcaaggcct ggcgtgaagc cttctctgcg
       61 ccgagtgcag gccagtggtg ccgaagagac tcggggaagt gaccagggcg gtgccctcag
      121 gccttaacgc acccgcccaa taggggcggg gctcgacctc ccggacccgc ccagccgagg
      181 cgctaggtct gcggattaac cgccctgcgt ctgcgggagt aggcctccct ccgctagaga
      241 catggagttt gcggagctga ttaagacccc gcgggtggac aatgtggtgc tgcaccggcc
      301 tttctacccc gctgtggaag ggaccctatg tctgacgggc caccacctga tcctgtcttc
      361 ccggcaggac aacactgagg agctctggct cctccattca aatatcgacg ccattgacaa
      421 acgatttgtg ggctctctgg gtactattat cataaaatgt aaagatttcc gaataattca
      481 gttggatatt cctggaatgg aggagtgttt aaatatagcc agttccatcg aggcattgtc
      541 cactctggac tcggtcaccc tgatgtaccc tttcttctac cgacccatgt ttgaagtgat
      601 tgaagatggc tggcattcct tccttcctga gcaagaattt gagttctact cttctgctac
      661 cagtgaatgg agactgagct atgtcaataa ggaattttcc atctgcccta cctacccacc
      721 aactgtcatt gtgcccaagt ccatcgatga tgaagcactt cggaaagtag cagccttccg
      781 acatgggggg cgcttcccag tcctgagcta ttaccataaa aagaatggca tggtaattat
      841 gcgaagtggt cagcccctga ctggcacaaa tgggcggagg tgcaaggaag atgagaagct
      901 gataaacgcc accctcaggg caggaaagcg tggctacctt attgacacca gatccctaaa
      961 tgtggcccag caagctagag ccaaaggagg tggctttgaa caggaggctc attatcccca
     1021 gtggaggcgg attcacaagt ccattgagag ataccatgtt cttcaggaga gcctaatcaa
     1081 acttgtggaa gcatgcaatg aacaaacaca cagcatggac cgatggctcg gcaagctgga
     1141 ggcctccaac tggctgacac acatcaagga gatcctgacc accgcctgcc tggccgccca
     1201 gtgcattgac agggaaggtg catcagtgtt gatccatggg acagaaggaa ctgattccac
     1261 actgcaagtg acttctctgg cccagatcat cctggaaccg agaagcagaa ccatccgagg
     1321 ctttgaagcc ctgatagagc gagagtggct gcaggctggt cacccgttcc agcagcgctg
     1381 tgcacagtca gcctattgca gcagcaagca gaagtgggag gcccccgtgt ttcttctctt
     1441 cctggactgt gtgtggcaga tcctgcggca gttcccctgc tcctttgagt ttaatgagca
     1501 ttttctcatc atgctctttg agcatgctta tgcctcacag ttcgggacgt tcctgggcaa
     1561 cagtgaaaac gagaggtgta agctgaagct acagcagaaa acaatgtctt tgtggtcatg
     1621 ggttaatcgg cccagtgaac tgagtaaatt caccaatccg ctttttgaag ccaacaacct
     1681 ggtcatctgg ccttctgtag ctccacagag tctccagctg tgggaaggaa tcttcctgcg
     1741 ctggagcaga tcctctaagt atctggatga agcctatgag gaaatggtta acatcattga
     1801 atataacaag gagttacaag ccaaggtcaa tgtcctgaga aggcagttgg ctgaattgga
     1861 aacagaggat gggctacgag agagtccctg aaagatctgc cgcctgtcct gaggacctgt
     1921 ccaggtctca gtccgtctcc ctctgtttgc ccttcagttc atgtacatgg tagccttgac
     1981 cttggctgta ggtgtgggat ccctgtatcg tagtggcctt ctcagcactt cgaggtggaa
     2041 gtcactaaca cacagatatg cctgttaggc cctttgcttt gggaacagaa ggtactgtca
     2101 cctcactaaa tatatgatac ctgtgccctg tgctgttccc catcaccact taagaatcca
     2161 cctacaacat gggccaggct tatttgcatt caagtataga ggtgttttta atggaaaaaa
     2221 aaaaaaaaaa aaaaaaaaaa aaaaaaa
//
