LOCUS       NM_001004254            2259 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus mitochondrial translational initiation factor 2
            (Mtif2), mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001004254 XM_223710
VERSION     NM_001004254.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2259)
  AUTHORS   Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein
            C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J and
            Hentze MW.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   2  (bases 1 to 2259)
  AUTHORS   Mootha VK, Bunkenborg J, Olsen JV, Hjerrild M, Wisniewski JR, Stahl
            E, Bolouri MS, Ray HN, Sihag S, Kamal M, Patterson N, Lander ES and
            Mann M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   3  (bases 1 to 2259)
  AUTHORS   Overman RG Jr, Enderle PJ, Farrow JM 3rd, Wiley JE and Farwell MA.
  TITLE     The human mitochondrial translation initiation factor 2 gene
            (MTIF2): transcriptional analysis and identification of a
            pseudogene
  JOURNAL   Biochim Biophys Acta 1628 (3), 195-205 (2003)
   PUBMED   12932832
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079421.1.
            
            On Sep 10, 2004 this sequence version replaced XM_223710.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079421.1, SRR8487230.103922.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132281
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2259
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14q22"
     gene            1..2259
                     /gene="Mtif2"
                     /note="mitochondrial translational initiation factor 2"
                     /db_xref="GeneID:305606"
                     /db_xref="RGD:1303046"
     exon            1..14
                     /gene="Mtif2"
                     /inference="alignment:Splign:2.1.0"
     exon            15..240
                     /gene="Mtif2"
                     /inference="alignment:Splign:2.1.0"
     CDS             22..2205
                     /gene="Mtif2"
                     /codon_start=1
                     /product="translation initiation factor IF-2,
                     mitochondrial"
                     /protein_id="NP_001004254.1"
                     /db_xref="GeneID:305606"
                     /db_xref="RGD:1303046"
                     /translation="MNQKLLKLEKLLRFHTICRQLHSLSQRRLLAWWKHGSAPASPVW
                     ADWLCARPWPTDVLTGSALHQHRLLVTKKEKRPPRSQLSPIKTKKEVEVWVGMTVEEL
                     ARAMAKDTDCVYEALLNTAIDIDSLEANSHLDEVWIKEVIKKAGMKLKWSKLKLERIR
                     ENKDAVRRPGADPALLKPRSPVVTIMGHVDHGKTTLLDKLRETQVAAMEVGGITQHIG
                     AFLVSLPSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHA
                     KDAGVPIILAINKCDKTDADPEKVKKELLAYDVVCEEYGGDVQAVHVSALTGKNLMAL
                     AEATIALAEMLELKADPTGPVEGTVIESFTDKGRGPVTTAIIQRGTLKKGSILVAGKS
                     WAKVRLMFDENGKTVNEAYPSMPVGIIGWRDLPSAGDEILEVQSEPRAREVVDWRKSE
                     QKEEKGKDDLKIMEEKRKEHQEAHRKAREKYGSLHWKQRSYIKYLERKEQRPLKPKEK
                     VERDSNVLPIIIKGDVDGSVEAILNLLDTYDASHECELELVHFGLGDISENDVTFAET
                     FDGVIYGFNVDAGSAIQQSAAQKGVKIKLHKIIYHLIEDLQEELSNRLPYKVEEYPIG
                     EASILATFTITEGKKKVPVAGCRVQKGQLERQKKFKLIRNGQVIWKGSLTSLKHHKDD
                     VLVIKTGVDCGLSLDEENVEFKVGDQVICYEENKVPTKTSWDPGF"
     exon            241..352
                     /gene="Mtif2"
                     /inference="alignment:Splign:2.1.0"
     exon            353..524
                     /gene="Mtif2"
                     /inference="alignment:Splign:2.1.0"
     exon            525..685
                     /gene="Mtif2"
                     /inference="alignment:Splign:2.1.0"
     exon            686..862
                     /gene="Mtif2"
                     /inference="alignment:Splign:2.1.0"
     exon            863..1002
                     /gene="Mtif2"
                     /inference="alignment:Splign:2.1.0"
     exon            1003..1127
                     /gene="Mtif2"
                     /inference="alignment:Splign:2.1.0"
     exon            1128..1332
                     /gene="Mtif2"
                     /inference="alignment:Splign:2.1.0"
     exon            1333..1585
                     /gene="Mtif2"
                     /inference="alignment:Splign:2.1.0"
     exon            1586..1726
                     /gene="Mtif2"
                     /inference="alignment:Splign:2.1.0"
     exon            1727..1891
                     /gene="Mtif2"
                     /inference="alignment:Splign:2.1.0"
     exon            1892..2032
                     /gene="Mtif2"
                     /inference="alignment:Splign:2.1.0"
     exon            2033..2232
                     /gene="Mtif2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcctgggaa ctgagagaaa catgaaccag aagctactga agttggaaaa gttgctacga
       61 tttcacacta tttgtaggca attgcacagc ctgagtcaaa gaagattgtt agcatggtgg
      121 aagcatgggt ctgcaccggc ttccccagtg tgggcagatt ggctgtgtgc ccggccttgg
      181 ccgacagacg tgcttactgg ttcagctttg catcagcaca gacttcttgt tacaaagaag
      241 gaaaaacgac caccgagatc tcagttgtct ccaataaaaa ctaaaaaaga ggtagaagta
      301 tgggttggaa tgactgttga agaactagcc agagcaatgg caaaagacac agattgtgta
      361 tatgaagctt tattgaacac cgccattgac atagactcac tagaagcaaa ctcacattta
      421 gacgaagtct ggatcaaaga agttataaag aaggcaggaa tgaagctgaa atggagcaaa
      481 ttaaaactgg agagaataag agaaaataag gatgctgtga gaaggcctgg ggcagatcca
      541 gctttactaa agccaaggtc cccagttgtt actataatgg gtcatgttga tcatgggaaa
      601 acgaccttac ttgacaaact tcgggaaact caagtggcag cgatggaagt tggaggcatt
      661 actcaacata ttggtgcttt tcttgtctct ctgccttctg gagaaaagat aacctttctt
      721 gatactccgg gacatgctgc tttctcagca atgagagcta gaggagctca ggtcactgac
      781 attgttgtgt tggttgtagc tgcagatgat ggggtaatga aacaaactgt ggaatccatt
      841 cagcacgcca aggatgcagg agttcctatt atccttgcaa taaataaatg tgacaagaca
      901 gatgctgatc ctgaaaaggt gaaaaaagag ctcctggctt atgatgtggt gtgtgaagag
      961 tatggtggtg atgttcaagc agtgcacgtc tctgcactaa caggaaagaa cctgatggct
     1021 ttggcagaag caacaattgc tctcgcagaa atgttggaac tgaaagcaga tcccacaggc
     1081 ccagtggaag gaacagtaat agagtctttc acagacaaag gaagaggtcc tgttacaaca
     1141 gctataattc aaagaggaac tctgaaaaaa ggctcaattc tagttgctgg gaagagttgg
     1201 gcaaaagttc gactaatgtt tgatgaaaat ggaaaaacag ttaatgaggc ctatcctagc
     1261 atgccagtgg gaatcatagg ctggagagac ctcccttctg caggagatga aattcttgaa
     1321 gtacagtctg agccaagggc ccgtgaagtt gttgactgga ggaagtctga gcaaaaagaa
     1381 gaaaagggca aagatgacct gaaaataatg gaagaaaagc gaaaggaaca ccaagaagca
     1441 catcggaaag cccgtgagaa gtatggcagc ctgcactgga agcagagatc atatataaag
     1501 taccttgaaa gaaaagaaca gagaccctta aagcccaaag aaaaggtaga aagggactca
     1561 aatgtacttc ctataattat taaaggtgac gttgatgggt ctgtggaggc catcttgaac
     1621 cttctggata cctatgatgc ttcccatgaa tgtgaactag aattagtgca ttttggattg
     1681 ggtgacatca gtgaaaatga tgttaccttt gctgagacat ttgatggtgt tatttatggc
     1741 tttaatgtgg atgcaggcag tgctatccag cagtcagctg cacaaaaggg agtcaagatt
     1801 aaacttcaca aaatcatcta ccatcttatt gaagatttgc aggaggaact aagcaacaga
     1861 ttgccctaca aggtggagga gtacccaata ggtgaggctt ctatactagc taccttcact
     1921 ataacagaag ggaagaaaaa agttcctgtt gctggctgca gagttcaaaa gggacagcta
     1981 gaaagacaga agaagtttaa attaatccgc aacggccaag ttatttggaa gggctcatta
     2041 acttcgctga aacaccataa agatgacgtt ttagttataa aaactggtgt ggactgtggt
     2101 cttagtttag atgaagaaaa cgtagaattt aaagtgggcg atcaagttat ctgttatgaa
     2161 gaaaataaag taccaactaa gacttcctgg gatccaggat tttaaatgtg cattaaaaat
     2221 ggtaaaaatg taaaaaaaaa aaaaaaaaaa aaaaaaaaa
//
