LOCUS       NM_001401041            4896 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus methenyltetrahydrofolate synthetase domain
            containing (Mthfsd), mRNA.
ACCESSION   NM_001401041 XM_039098337
VERSION     NM_001401041.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4896)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   2  (bases 1 to 4896)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000019.1.
            
            On Feb 1, 2022 this sequence version replaced XM_039098337.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643429.56293.1,
                                           SRR26643292.61821.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-54                JAXUCZ010000019.1  66086827-66086880   c
            55-161              JAXUCZ010000019.1  66084973-66085079   c
            162-275             JAXUCZ010000019.1  66083641-66083754   c
            276-389             JAXUCZ010000019.1  66082666-66082779   c
            390-480             JAXUCZ010000019.1  66080973-66081063   c
            481-593             JAXUCZ010000019.1  66079647-66079759   c
            594-719             JAXUCZ010000019.1  66079392-66079517   c
            720-4896            JAXUCZ010000019.1  66072952-66077128   c
FEATURES             Location/Qualifiers
     source          1..4896
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19q12"
     gene            1..4896
                     /gene="Mthfsd"
                     /note="methenyltetrahydrofolate synthetase domain
                     containing"
                     /db_xref="GeneID:687539"
                     /db_xref="RGD:1584226"
     exon            1..54
                     /gene="Mthfsd"
                     /inference="alignment:Splign:2.1.0"
     CDS             39..1217
                     /gene="Mthfsd"
                     /codon_start=1
                     /product="methenyltetrahydrofolate synthase
                     domain-containing protein"
                     /protein_id="NP_001387970.1"
                     /db_xref="GeneID:687539"
                     /db_xref="RGD:1584226"
                     /translation="MEARAGDVSKQSIRERIWDYMESHNIADFPRPVHHRIPNFKGSY
                     LAGQSIRDLEVFAGTQEVKVDPDKPLEGVRLLALQSRKTLLVPTPRLRTGLFNKIIPP
                     PGATKDILRKCATSQGVRNFSVPVGLDSNVLVDLVVVGSVAVSEKGWRIGKGEGYADL
                     EYAMMVSMGAVHEGTLVVTIVHDCQVVDIPEALLEDHDLTVDYILTPTRVIATGCARP
                     KPTGILWSKVSCEMLTKIPVLRSLREREKRAGTDVTLQAEPGNTQQPAPSTVRRPQDR
                     PQSQPAPSTVRRPQDRPQSQAGFRGRSHSSLEGTDTHLAATVCLGNLPYSARVRELKR
                     ALQELGAVPLRLTWQGPQHRAILHYTDSAAAQQAASLLQGLRLGDNALRVSLGQQRDT
                     "
     exon            55..161
                     /gene="Mthfsd"
                     /inference="alignment:Splign:2.1.0"
     exon            162..275
                     /gene="Mthfsd"
                     /inference="alignment:Splign:2.1.0"
     exon            276..389
                     /gene="Mthfsd"
                     /inference="alignment:Splign:2.1.0"
     exon            390..480
                     /gene="Mthfsd"
                     /inference="alignment:Splign:2.1.0"
     exon            481..593
                     /gene="Mthfsd"
                     /inference="alignment:Splign:2.1.0"
     exon            594..719
                     /gene="Mthfsd"
                     /inference="alignment:Splign:2.1.0"
     exon            720..4896
                     /gene="Mthfsd"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aagctctacg ggaggcgtcg ctcggtgacg tgttggtcat ggaggcccgg gcgggagatg
       61 tctccaagca aagcatacgt gaacggattt gggactacat ggaatcccat aatatagctg
      121 attttccccg acctgttcat cacaggatcc ccaacttcaa ggggtcctac ctggctggcc
      181 aaagcatcag agacctggaa gtctttgctg ggacacagga agtgaaagtg gaccctgata
      241 agcccctgga aggtgtccgc ttactggcac tgcagagcag aaaaacactg ctggtcccaa
      301 cacctcgact gaggacaggg ctgtttaaca agatcatacc accccctgga gccaccaaag
      361 acatactgag gaaatgtgcc acctcccagg gtgtgcggaa cttcagcgtc ccggtgggct
      421 tggattccaa tgtcctcgtg gatttagttg tggtgggatc tgttgctgtg tctgagaaag
      481 gctggcgaat tgggaaggga gaaggctacg ctgatcttga atatgccatg atggtgtcga
      541 tgggagctgt ccacgagggg acattggtcg tcacgattgt ccacgactgc caggtcgttg
      601 acatccctga ggctctcctg gaggaccacg acctcactgt agactacatc ctcactccca
      661 ccagggtcat cgccacaggc tgtgcacgcc caaagccaac agggatcctg tggtccaagg
      721 tcagctgtga gatgcttacg aaaatcccag tgctcaggag cctccgtgag cgagagaagc
      781 gggcggggac cgatgtcact cttcaggctg agcctggcaa cacacagcag ccagctccca
      841 gcactgtcag gaggccccag gatagaccac agtcacaacc agctcccagc actgtcagga
      901 gaccccagga tagaccacag tcacaagcag gtttccgagg aaggtcccat agctccctgg
      961 aggggacgga cacccaccta gctgccactg tgtgcttggg aaaccttccc tacagtgctc
     1021 gtgtgcgtga gctgaagcga gccctccagg agctgggggc ggtgcccctg aggctaacct
     1081 ggcaggggcc acagcacaga gcaattctac actatacaga ctcagctgct gcccagcagg
     1141 ctgcctctct cctacagggc ctgcgactgg gtgacaatgc tttgagggtg tcactggggc
     1201 agcagaggga tacgtgacct ggtgtgcagc ccccagctgt gccctttctg ctgctgggat
     1261 gtttctggca tgtgacagtg ccattggtga tgacctgctg ctgtgcggcc tgctctgctc
     1321 ctgggaagag gctgcacttc cctgatgggt ggggtgatag caggcagcac agcatgctac
     1381 cacactcgct accacattcg ggatgctgtg agtgcagacc catccagttc tggttcttgt
     1441 gaaatccacg tgatgttctc tgggtacaga tggttcaggg acagagcagc ctggacaaga
     1501 ggtagacagt ggaaacctgt ttgaggatgt ctgagagaga gagcagagac tgtggcaaga
     1561 atcgagtgcc ctgtgaccat tggaagccac cactccaacc cgagcccagc agaacaggag
     1621 tggggagagc ggggcttctg catgcagaga gcacaagcct cgagtttgag ttctgttcct
     1681 ggaaactctg tgttgtgtgc acatgtgatg gcgtctaccc aggctgctta gggcctcccc
     1741 atccctcagg tgaggaggtg aggcacttgg caggtgcctg tgctctccca gaagcacttg
     1801 cgccattgat cctaaggaaa cacataagca tttatgtgga gagttgattc tgttcaaata
     1861 cgcatgcctg ggaagttttt ttgtgtttac cagtgggtct tccacagtga cggatggcat
     1921 tgtcctttgc cccagaaggg caggcctcgc tcatattaaa ggaagggaac ttgtgtacat
     1981 ctgcttgcct tagaaaacga tagttcagta gccaccgctt ccaggtagtc acaggggtca
     2041 cgaggggtgg ctgagggaag cagactcagg ctgtgccggc ctctagcctg gcaacctgtt
     2101 ggcctggccc caacccccac tcctgcctca cacagccact gaccacccca tcctcacctg
     2161 ctctgctctc ctcggggtcc ttgcctgccc ctcatgtccc ttcttcacat tgtgtcccac
     2221 tgagacagtg cctacaggtt agcagcatgg agtcgtctgt tccctcctgc tgcaggccag
     2281 cagggtgtga acaactcagg aaatccgtgt tacatgagct gggagatggg agacaacctt
     2341 tacccagaag ccaaccaagc ctgacccatc agtaagtgtc actctggcct tccagatggt
     2401 gcgggcctcc tgctactgtg gccagagtaa tccagatgtg ttggctccgt ctaagccact
     2461 tgcgtttgtg taaagtgtgt aagcgatgaa gcccaggtgc cctcagtcta agctctggta
     2521 gatgctacag ggcgttccct gtctcaggtg cctttgaggt ctggctctcc aggtgacagg
     2581 agccacaggt gacagagtca ctgcgttctt tgtcactaca gctgcctagc acacacaatc
     2641 aaagtggaca ggaagagttg ctgtccagca ctgaggtggc aaaaacactc taagtgtcgc
     2701 tgaggcttct gggtccctcc attcttccac tcgtgttttt ctgctttgcc aatagtggag
     2761 acctgggcag gaggatggct gtttgcaaga gttcatcctc aggactcatc tcactctgga
     2821 ttaatttggg taactgttgc agtgatgaac caccatgacc aaagcaactt ggggaggaaa
     2881 gggtttattt cactcacagt tccatagaaa ctggtcatca tcaaaatcag tgaggccagg
     2941 aactcgaata gggcaggaac ctggagtagc agctgacgca gaggccatgg cgggatgttg
     3001 cttactggct tgctctccat ggcctgctca gcttgctttc ttatagaacc caggaccaca
     3061 gccaaggggt ggcactgcct acaatgtggt ctgggccctc cccatcaatc attttcttag
     3121 aagaaaatgt tctacaggcc tctctgcagc ctgatcttac agagggcttt tccccagttg
     3181 aggttccctc agatgattct accttgtgtc aatctgatgt caaactatcc agcacagtac
     3241 tggcctcttc ctgtgtgtgc tcgacctgca tcctcgtcgt cctgttgaga gcagagctct
     3301 gcaccctgcc atgacagact gaagctgagt aaaccctttt gagcatcttg acaagctaaa
     3361 gcaggaagat gcaaaccaac gggtttccct gcaaccatta taatgtagct tctagaaacg
     3421 gaatagcaag ggctagagaa gtagagcctt caagagccat tactgccctt ccagaagacc
     3481 cgagttcagt tccctccacc catgatgtca caaagctcac atgcacccac agcttcagcc
     3541 acaggaatct gacacccttg tctgacctcc actgcgtgcg cacgcatacc agcagtaaaa
     3601 ctcgtaaagt ggtcgagact gatgagtttg acagaaaatg gttgcagatc cacagaaaga
     3661 tgtcagtaga agttcctcag ggaactaaga aaacagagca tcaggaattg ttacccgcaa
     3721 gaccagagga ttgcagaagt tgacctctgg tctcccacat gcgaacacac acacacacac
     3781 acacacacac acacacacac acacacatga aggacgtgta aacagaatga agctggcaga
     3841 ggagactcag agcggtgacc tacccaatgc tggcttctaa ccctagttgg agatgtggtt
     3901 tggttccaag gttcaaactt ccaggtggtg ttgctggcac tccctccttt cctgtggcct
     3961 ttcacagtga agccacactt agtacagaag ccatggtacc tcagaaggag agaccagagc
     4021 agcagcagtc actgtcctga ggagcaagat ggaggcttga aggctagaac gccggggaat
     4081 aggcagctaa gcagaggggc cactttacaa gtcctggggt ttctgttctg taaagaagca
     4141 atgtgggatg aaagggctta tctgtccata ttacagtctg tcattaaggg aagtcaggcc
     4201 aggggtgcag gtcaactgac acagagacca tggtggaggg ctgctcctca cgactcacta
     4261 agcctgcttt cttgtagaac ccaagactac caacctaggg gtgacacagc tctccctgtc
     4321 agccgtcaat caagaaaggg caccaaaagc ttgcccacat gcctgtgtag tggggacatg
     4381 tcctcaacta aggtttcctc ttccaaaaat gactccagtt tgtgtcaagt tggtctaaga
     4441 ctagccgtca cattagggga agcatgtctg tctgtggcca ggcacccata accactgccc
     4501 acagaccaga ccagcactgt ggatggccag acccaggaaa gcactcgtgt aaaggcacag
     4561 gcctgatgat cttctgtggc ctgagatgca gtcttctgtc tttataaaag gagccaacac
     4621 aggctcacct cctagtcctg gcctgatggc gagtcctgga cagctgggct gccattaccc
     4681 ccaaccccac atcccaggca cctgggcctg atgccacctt ccccgggtcc tggacacctg
     4741 gcctgtgtgt gatgcttctg atgttgctgt tctcatggcc ccagcagaag taacgaaagg
     4801 cagccatgct cctgcacctt tttctgggct ctctgactag aacctcaaat agaagatatg
     4861 tcctaaaata aagagaacat cgattttatt agttac
//
