LOCUS       NM_001401716            1332 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus mitochondrial ribosome-associated GTPase 1
            (Mtg1), mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001401716 XM_003749002
VERSION     NM_001401716.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1332)
  AUTHORS   Faraj Shaglouf,L.H., Ranjpour,M., Wajid,S. and Jain,S.K.
  TITLE     Elevated expression of cellular SYNE1, MMP10, and GTPase1 and their
            regulatory role in hepatocellular carcinoma progression
  JOURNAL   Protoplasma 257 (1), 157-167 (2020)
   PUBMED   31428857
  REMARK    GeneRIF: Elevated expression of cellular SYNE1, MMP10, and GTPase1
            and their regulatory role in hepatocellular carcinoma progression.
REFERENCE   2  (bases 1 to 1332)
  AUTHORS   Kotani,T., Akabane,S., Takeyasu,K., Ueda,T. and Takeuchi,N.
  TITLE     Human G-proteins, ObgH1 and Mtg1, associate with the large
            mitochondrial ribosome subunit and are involved in translation and
            assembly of respiratory complexes
  JOURNAL   Nucleic Acids Res 41 (6), 3713-3722 (2013)
   PUBMED   23396448
REFERENCE   3  (bases 1 to 1332)
  AUTHORS   Cattaruzza,M., Schafer,K. and Hecker,M.
  TITLE     Cytokine-induced down-regulation of zfm1/splicing factor-1 promotes
            smooth muscle cell proliferation
  JOURNAL   J Biol Chem 277 (8), 6582-6589 (2002)
   PUBMED   11748220
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Feb 22, 2022 this sequence version replaced XM_003749002.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ212842.1, SRR26643429.4038.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-127               JAXUCZ010000001.1  204361214-204361340
            128-192             JAXUCZ010000001.1  204361876-204361940
            193-297             JAXUCZ010000001.1  204363565-204363669
            298-378             JAXUCZ010000001.1  204367603-204367683
            379-435             JAXUCZ010000001.1  204368074-204368130
            436-526             JAXUCZ010000001.1  204368390-204368480
            527-588             JAXUCZ010000001.1  204369767-204369828
            589-685             JAXUCZ010000001.1  204370188-204370284
            686-767             JAXUCZ010000001.1  204370626-204370707
            768-880             JAXUCZ010000001.1  204373045-204373157
            881-1332            JAXUCZ010000001.1  204373466-204373917
FEATURES             Location/Qualifiers
     source          1..1332
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q41"
     gene            1..1332
                     /gene="Mtg1"
                     /note="mitochondrial ribosome-associated GTPase 1"
                     /db_xref="GeneID:100910751"
                     /db_xref="RGD:6497155"
     exon            1..127
                     /gene="Mtg1"
                     /inference="alignment:Splign:2.1.0"
     CDS             19..999
                     /gene="Mtg1"
                     /note="mitochondrial GTPase 1-like; putative GTP-binding
                     protein"
                     /codon_start=1
                     /product="mitochondrial ribosome-associated GTPase 1"
                     /protein_id="NP_001388645.1"
                     /db_xref="GeneID:100910751"
                     /db_xref="RGD:6497155"
                     /translation="MRLWPQAWSAVGAAWRECFPLQGHDVARWFPGHMAKGLKKMQSS
                     LKLVDCVIEVHDARIPFSGRNPLFQELLGLKPHLLVLNKMDLADLTEQQKIVQHLEEK
                     GLRNVIFTNCIKDENIKQIIPKVTELIGCSYRYHRAENPEYCIMVVGVPNVGKSSLIN
                     SLRRQHLRTGKAARVGGEPGITRAVTSRIQVCERPLMFLLDTPGVLAPRIQSVETGLK
                     LALCGTVLDHLVGEETMADYLLYTLNRHGLFGYVQHYALASASDHIEWVLKNVAIKLG
                     KTRKVKVLTGTGNVNVIQPDYAIAARDFLRTFRSGRLGQVMLDRDIIPAC"
     exon            128..192
                     /gene="Mtg1"
                     /inference="alignment:Splign:2.1.0"
     exon            193..297
                     /gene="Mtg1"
                     /inference="alignment:Splign:2.1.0"
     exon            298..378
                     /gene="Mtg1"
                     /inference="alignment:Splign:2.1.0"
     exon            379..435
                     /gene="Mtg1"
                     /inference="alignment:Splign:2.1.0"
     exon            436..526
                     /gene="Mtg1"
                     /inference="alignment:Splign:2.1.0"
     exon            527..588
                     /gene="Mtg1"
                     /inference="alignment:Splign:2.1.0"
     exon            589..685
                     /gene="Mtg1"
                     /inference="alignment:Splign:2.1.0"
     exon            686..767
                     /gene="Mtg1"
                     /inference="alignment:Splign:2.1.0"
     exon            768..880
                     /gene="Mtg1"
                     /inference="alignment:Splign:2.1.0"
     exon            881..1332
                     /gene="Mtg1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcttccgaca ccagcgacat gaggctgtgg ccgcaggcat ggagtgctgt cggggccgct
       61 tggcgcgagt gtttccccct gcaaggtcac gatgtagcac gctggtttcc cggccacatg
      121 gccaagggac taaagaagat gcagagcagt ctgaagttgg tggattgtgt tatcgaggtt
      181 catgacgccc ggatcccatt ttcaggtcga aaccctctgt tccaagagct acttggtctg
      241 aagccccatt tgcttgtcct gaacaaaatg gacttggcag atcttacaga gcagcagaaa
      301 attgtccagc acttagaaga aaaaggcctg agaaatgtta tttttaccaa ctgtataaag
      361 gatgaaaaca tcaagcagat catcccaaaa gtcacagaac tgatcggatg cagctaccgc
      421 taccaccggg cagagaaccc agaatactgc atcatggtgg tcggtgtccc caatgtaggc
      481 aaatcctccc tcatcaactc cttgaggcgg cagcacctca ggacaggaaa agctgccaga
      541 gtgggtggtg agccaggaat cacgagagct gtgacttcca gaatccaggt atgtgagcgt
      601 ccactgatgt tcttgctgga tacccctggg gtgctggctc ctcggattca aagtgtggag
      661 acaggcctga agctggccct gtgtggaact gtgttggacc accttgttgg ggaagagacc
      721 atggctgatt atctccttta caccctcaac aggcatgggc tatttgggta tgtgcagcac
      781 tatgccctgg ccagtgcctc tgaccacata gagtgggtgc tgaagaacgt ggccatcaag
      841 ctggggaaga cacggaaagt gaaggttctc acaggcacag gtaatgtcaa cgttatccag
      901 ccggattatg ccattgcagc ccgagacttc ctccgtacct tccgcagtgg gcggttgggc
      961 caggtgatgc tggaccgtga cattatacct gcttgctgat gacattgacc cttgtactgg
     1021 ctggctggag tatggtctcc tgcatattct atggactaca gctggagtgt ttaatgctta
     1081 gacctattcc tccagttcag aagctctctg tgctggtacc tgagactcag gccccagctc
     1141 caaaggggac tatattctcc tgtctaccag agtctgctca gtgtgcttac tgctgtcagg
     1201 ccccaggagt cctgcctctg tggcttggtc aggaggtttt ctcagcctca agaagagata
     1261 aatgctatcc cagaggagtc taagttataa tctgtaattt aaaaaatgag ttaaaaggcc
     1321 cacttaaaaa ta
//
