LOCUS       NM_001106705            2120 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus metastasis associated 1 family, member 3 (Mta3),
            mRNA.
ACCESSION   NM_001106705 XM_001061120 XM_039078112 XM_216633
VERSION     NM_001106705.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2120)
  AUTHORS   Li,Q., Li,Z., Lin,Y., Che,H., Hu,Y., Kang,X., Zhang,Y., Wang,L. and
            Zhang,Y.
  TITLE     High glucose promotes hepatic fibrosis via miR-32/MTA3-mediated
            epithelial-to-mesenchymal transition
  JOURNAL   Mol Med Rep 19 (4), 3190-3200 (2019)
   PUBMED   30816482
  REMARK    GeneRIF: The results indicated that miR32 and MTA3 may be
            considered as novel drug targets in the prevention and treatment of
            liver fibrosis under hyperglycemic conditions. These finding
            improves the understanding of the progression of liver
            fibrogenesis.
            Erratum:[Mol Med Rep. 2022 Oct;26(4):. PMID: 36004471]
REFERENCE   2  (bases 1 to 2120)
  AUTHORS   Basta,J. and Rauchman,M.
  TITLE     The nucleosome remodeling and deacetylase complex in development
            and disease
  JOURNAL   Transl Res 165 (1), 36-47 (2015)
   PUBMED   24880148
  REMARK    Review article
REFERENCE   3  (bases 1 to 2120)
  AUTHORS   Xuan,C., Wang,Q., Han,X., Duan,Y., Li,L., Shi,L., Wang,Y., Shan,L.,
            Yao,Z. and Shang,Y.
  TITLE     RBB, a novel transcription repressor, represses the transcription
            of HDM2 oncogene
  JOURNAL   Oncogene 32 (32), 3711-3721 (2013)
   PUBMED   22926524
REFERENCE   4  (bases 1 to 2120)
  AUTHORS   Qin,J., Whyte,W.A., Anderssen,E., Apostolou,E., Chen,H.H.,
            Akbarian,S., Bronson,R.T., Hochedlinger,K., Ramaswamy,S.,
            Young,R.A. and Hock,H.
  TITLE     The polycomb group protein L3mbtl2 assembles an atypical
            PRC1-family complex that is essential in pluripotent stem cells and
            early development
  JOURNAL   Cell Stem Cell 11 (3), 319-332 (2012)
   PUBMED   22770845
REFERENCE   5  (bases 1 to 2120)
  AUTHORS   Kwintkiewicz,J., Padilla-Banks,E., Jefferson,W.N., Jacobs,I.M.,
            Wade,P.A. and Williams,C.J.
  TITLE     Metastasis-associated protein 3 (MTA3) regulates G2/M progression
            in proliferating mouse granulosa cells
  JOURNAL   Biol Reprod 86 (3), 1-8 (2012)
   PUBMED   22075476
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2120)
  AUTHORS   Ma,P., Lin,S., Bartolomei,M.S. and Schultz,R.M.
  TITLE     Metastasis tumor antigen 2 (MTA2) is involved in proper imprinted
            expression of H19 and Peg3 during mouse preimplantation development
  JOURNAL   Biol Reprod 83 (6), 1027-1035 (2010)
   PUBMED   20720167
REFERENCE   7  (bases 1 to 2120)
  AUTHORS   Florea,L., Di Francesco,V., Miller,J., Turner,R., Yao,A.,
            Harris,M., Walenz,B., Mobarry,C., Merkulov,G.V., Charlab,R.,
            Dew,I., Deng,Z., Istrail,S., Li,P. and Sutton,G.
  TITLE     Gene and alternative splicing annotation with AIR
  JOURNAL   Genome Res 15 (1), 54-66 (2005)
   PUBMED   15632090
REFERENCE   8  (bases 1 to 2120)
  AUTHORS   Fujita,N., Jaye,D.L., Geigerman,C., Akyildiz,A., Mooney,M.R.,
            Boss,J.M. and Wade,P.A.
  TITLE     MTA3 and the Mi-2/NuRD complex regulate cell fate during B
            lymphocyte differentiation
  JOURNAL   Cell 119 (1), 75-86 (2004)
   PUBMED   15454082
REFERENCE   9  (bases 1 to 2120)
  AUTHORS   Simpson,A., Uitto,J., Rodeck,U. and Mahoney,M.G.
  TITLE     Differential expression and subcellular distribution of the mouse
            metastasis-associated proteins Mta1 and Mta3
  JOURNAL   Gene 273 (1), 29-39 (2001)
   PUBMED   11483358
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On or before Dec 20, 2021 this sequence version replaced
            XM_039078112.1, NM_001106705.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643429.22567.1,
                                           SRR26643294.24300.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-130               JAXUCZ010000006.1  16739356-16739485   c
            131-198             JAXUCZ010000006.1  16737167-16737234   c
            199-292             JAXUCZ010000006.1  16731156-16731249   c
            293-419             JAXUCZ010000006.1  16708740-16708866   c
            420-483             JAXUCZ010000006.1  16690608-16690671   c
            484-601             JAXUCZ010000006.1  16688826-16688943   c
            602-704             JAXUCZ010000006.1  16681264-16681366   c
            705-804             JAXUCZ010000006.1  16677780-16677879   c
            805-993             JAXUCZ010000006.1  16667244-16667432   c
            994-1068            JAXUCZ010000006.1  16660931-16661005   c
            1069-1127           JAXUCZ010000006.1  16658460-16658518   c
            1128-1249           JAXUCZ010000006.1  16654156-16654277   c
            1250-1398           JAXUCZ010000006.1  16651339-16651487   c
            1399-1621           JAXUCZ010000006.1  16650439-16650661   c
            1622-1708           JAXUCZ010000006.1  16643299-16643385   c
            1709-1855           JAXUCZ010000006.1  16639795-16639941   c
            1856-2120           JAXUCZ010000006.1  16628015-16628279   c
FEATURES             Location/Qualifiers
     source          1..2120
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q12"
     gene            1..2120
                     /gene="Mta3"
                     /note="metastasis associated 1 family, member 3"
                     /db_xref="GeneID:100362346"
                     /db_xref="RGD:1306803"
     exon            1..130
                     /gene="Mta3"
                     /inference="alignment:Splign:2.1.0"
     CDS             103..1881
                     /gene="Mta3"
                     /note="metastasis associated 3"
                     /codon_start=1
                     /product="metastasis-associated protein MTA3"
                     /protein_id="NP_001100175.2"
                     /db_xref="GeneID:100362346"
                     /db_xref="RGD:1306803"
                     /translation="MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTASGNVEAKVVC
                     FYRRRDISNTLIMLADKHAKETEEESETTVEADLTEKQKHQLKHRELFLSRQYESLPA
                     THIRGKCSVALLNETESVLSYLDKEDTFFYSLVYDPSVKTLLADKGEIRVGPKYQADI
                     PDVLPEGDSDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQ
                     PSLHMSAAAASRDITLFHAMDTLYRHGYDLSSAISVLVPLGGPVLCRDEMEEWSASEA
                     SLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKL
                     KQVYIPTYKPNPNQISSSNGKAGTVNGAVGTPFQPQSALLGRACESCYATQSHQWYSW
                     GPPNMQCRLCATCWLYWKKYGGLKMPTQTDEEKAPSPAAEDPRVRSHLSRQALQGMPV
                     RNTGSPKSAVKTRQAFFLHTTYFTKIARQVCKNTLRLRQAARRPFVAINYAAIRAEYA
                     DRHAELSGSPLKSKSTRKPLSCIIGYLEIHPAKKPNVIRSPPSLQTPTTKRMLTTPNH
                     TSLSILGKRNYSHHNGLDGSERWLSR"
     exon            131..198
                     /gene="Mta3"
                     /inference="alignment:Splign:2.1.0"
     exon            199..292
                     /gene="Mta3"
                     /inference="alignment:Splign:2.1.0"
     exon            293..419
                     /gene="Mta3"
                     /inference="alignment:Splign:2.1.0"
     exon            420..483
                     /gene="Mta3"
                     /inference="alignment:Splign:2.1.0"
     exon            484..601
                     /gene="Mta3"
                     /inference="alignment:Splign:2.1.0"
     exon            602..704
                     /gene="Mta3"
                     /inference="alignment:Splign:2.1.0"
     exon            705..804
                     /gene="Mta3"
                     /inference="alignment:Splign:2.1.0"
     exon            805..993
                     /gene="Mta3"
                     /inference="alignment:Splign:2.1.0"
     exon            994..1068
                     /gene="Mta3"
                     /inference="alignment:Splign:2.1.0"
     exon            1069..1127
                     /gene="Mta3"
                     /inference="alignment:Splign:2.1.0"
     exon            1128..1249
                     /gene="Mta3"
                     /inference="alignment:Splign:2.1.0"
     exon            1250..1398
                     /gene="Mta3"
                     /inference="alignment:Splign:2.1.0"
     exon            1399..1621
                     /gene="Mta3"
                     /inference="alignment:Splign:2.1.0"
     exon            1622..1708
                     /gene="Mta3"
                     /inference="alignment:Splign:2.1.0"
     exon            1709..1855
                     /gene="Mta3"
                     /inference="alignment:Splign:2.1.0"
     exon            1856..2120
                     /gene="Mta3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcccccgtgg cgaggcggcg gcggcggcgg cggcggcggt cgaggctgag gcggcggcgg
       61 cgggcggggc tcgactcggg ctccgcgggc gggcgggcgg acatggcggc caacatgtac
      121 cgggtcggag attatgttta ctttgagaat tcgtccagca acccatacct aatcagaagg
      181 atagaggaac tcaacaagac tgcaagcggc aatgtggaag ccaaagtagt ctgcttttat
      241 agaagacggg acatctccaa cacgctgata atgcttgccg ataagcatgc taaagaaact
      301 gaggaagaat cagagacgac ggttgaggct gacttgacgg agaagcagaa gcaccagctg
      361 aaacacaggg agctctttct gtcccgccag tatgagtccc tgcctgcaac acatatcagg
      421 gggaagtgca gcgtggccct gctgaacgag acagaatcag tgctgtcata ccttgacaaa
      481 gaggatacct tcttctactc attggtgtat gacccttccg tgaaaacatt attggctgac
      541 aaaggtgaaa tcagagtggg cccaaagtac caagccgaca ttccagacgt gctgccggaa
      601 ggcgactcag atgagaggga acaatcaaaa ttggaagtta aggtttggga ccccaatagt
      661 ccgcttacgg atcgacagat tgaccagttt ttagttgtag cccgtgccgt gggaacattt
      721 gcccgtgccc tggattgcag cagctctgtg aggcagccca gcctgcatat gagcgcggct
      781 gcggcctccc gagacatcac cttgttccat gccatggaca cgctgtatag gcacggctat
      841 gacctcagca gtgccatcag tgtgctggtg ccactcggag ggccggtcct gtgcagggac
      901 gagatggagg agtggtctgc ctctgaagcc agcttattcg aagaagcact ggaaaaatat
      961 ggcaaagatt tcaatgacat ccgtcaggac tttctcccat ggaagtcctt gactagcatc
     1021 attgaatatt attacatgtg gaaaactact gacagatacg ttcaacagaa gcgcctaaaa
     1081 gctgcggaag ccgagagcaa actgaaacaa gtgtacatcc caacttacaa accaaatccc
     1141 aaccaaatct ccagcagcaa cggcaaggct ggcactgtga atggagctgt ggggaccccg
     1201 ttccagcccc agagcgcact cctaggacga gcctgtgaga gctgctatgc cacacagtct
     1261 caccagtggt attcctgggg cccacctaat atgcagtgta gactctgtgc gacctgctgg
     1321 ctgtattgga aaaagtacgg aggtctgaaa atgcccacgc agacggacga ggagaaggct
     1381 cccagccctg ccgcagagga cccgcgcgtg agaagccacc tgtcccggca ggccttgcag
     1441 ggcatgccgg tccggaacac cgggagcccc aagtcggccg tgaagacccg ccaagctttc
     1501 ttcctccata ctacgtattt cacaaaaatt gctcgtcagg tctgcaaaaa caccctgcgg
     1561 ctgcggcagg cagcgagacg gccgtttgtt gctattaact atgctgccat tagggcagaa
     1621 tatgcagaca gacatgctga actttctgga agcccactga aaagcaagag caccaggaaa
     1681 cctttgtcat gtatcattgg gtatttagag atccatcctg caaagaaacc taatgtaatt
     1741 cgatctccgc cgagcctgca aactccaact accaagagga tgctcaccac tccaaaccac
     1801 acgtccctga gcattctggg aaaaagaaac tacagccatc acaacggtct agatgggtca
     1861 gaacgatggc taagcaggta aaggcgctgc caccaagcct gtgacctgaa ttcgatccct
     1921 gggaccctca tggtgaaagg agagaaccga ctcctacaag tgtcctctga cctccacacg
     1981 tgcactgtgg tacgcacaca ctcacacaca cacacacaca cacacacaca tacactcaca
     2041 cacacacatt aataaaatgt aatgaaattt tataaaaata taaaaaatat ttaaaaataa
     2101 taaaatgtaa tgaaaatggc
//
