LOCUS       NM_053712               2310 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus msh homeobox 3 (Msx3), mRNA.
ACCESSION   NM_053712
VERSION     NM_053712.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2310)
  AUTHORS   Matsui,H., Takahashi,T. and Raghow,R.
  TITLE     The mechanism of biogenesis and potential function of the two
            alternatively spliced mRNAs encoded by the murine Msx3 gene
  JOURNAL   Mol Cell Biochem 267 (1-2), 1-11 (2004)
   PUBMED   15663180
REFERENCE   2  (bases 1 to 2310)
  AUTHORS   Liu,Y., Helms,A.W. and Johnson,J.E.
  TITLE     Distinct activities of Msx1 and Msx3 in dorsal neural tube
            development
  JOURNAL   Development 131 (5), 1017-1028 (2004)
   PUBMED   14973289
REFERENCE   3  (bases 1 to 2310)
  AUTHORS   Mehra-Chaudhary,R., Matsui,H. and Raghow,R.
  TITLE     Msx3 protein recruits histone deacetylase to down-regulate the Msx1
            promoter
  JOURNAL   Biochem J 353 (Pt 1), 13-22 (2001)
   PUBMED   11115394
REFERENCE   4  (bases 1 to 2310)
  AUTHORS   Ohm,W.W., Cullen,B.F., Amory,D.W. and Kennedy,R.D.
  TITLE     Delayed seizure activity following enflurane anesthesia
  JOURNAL   Anesthesiology 42 (3), 367-368 (1975)
   PUBMED   1115394
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence because no single transcript was available for the
            full length of the gene. The extent of this transcript is supported
            by orthologous data.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.5855.1,
                                           SRR26643296.3087.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760386, SAMEA5760393
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-302               JAXUCZ010000001.1  204271315-204271616 c
            303-2310            JAXUCZ010000001.1  204268688-204270695 c
FEATURES             Location/Qualifiers
     source          1..2310
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q41"
     gene            1..2310
                     /gene="Msx3"
                     /note="msh homeobox 3"
                     /db_xref="GeneID:114504"
                     /db_xref="RGD:620932"
     exon            1..302
                     /gene="Msx3"
                     /inference="alignment:Splign:2.1.0"
     CDS             89..703
                     /gene="Msx3"
                     /codon_start=1
                     /product="homeo box, msh-like 3"
                     /protein_id="NP_446164.1"
                     /db_xref="GeneID:114504"
                     /db_xref="RGD:620932"
                     /translation="MARATLDMNAAGLEARGGGHIEQGPLPFSVESLLEAERVRGSES
                     GELGEERPPGASKPGAWPPPVAHSCPPRAPSPPPCTLRKHKTNRKPRTPFTTAQLLAL
                     ERKFHQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKLTAKPL
                     LPAAFALPFPLGTQLHSSAATFGGNAVPGILAGPVAAYGMYYLS"
     exon            303..2310
                     /gene="Msx3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cacggaaccc agggacctgg caaaataaac cgccgttggg ttttacgcgt ctcagtcagg
       61 cggctagccc gcacccgcta tcccatgcat ggcccgggca acactcgaca tgaacgcggc
      121 ggggctcgaa gctcgcggcg ggggccacat agagcaggga ccactcccct tcagcgtcga
      181 gtcactgctg gaggctgagc gcgtaagggg ctccgagtct ggggagctgg gggaggagag
      241 gccgcccggc gcctcgaagc ctggagcctg gcccccaccg gtcgcgcact catgcccccc
      301 acgtgccccc agccctccac cctgcaccct tcgcaaacac aaaaccaatc gcaaaccacg
      361 aacacccttc accaccgcgc agctgctggc tctggagcgc aagtttcacc agaagcaata
      421 cttgtccatt gccgagcgcg ccgagttctc cagcagcttg agcctcactg aaactcaggt
      481 caagatctgg tttcagaatc gccgagccaa ggccaagcgg ctgcaggagg ccgagctgga
      541 gaagctgaag ctgactgcca agccactact gccggcggca tttgcccttc ccttcccact
      601 gggcacccag ctgcacagct ccgccgccac tttcggcggc aacgctgttc ctgggatcct
      661 cgctgggccg gtcgcggctt atggcatgta ctacttgtct tagagcatgg aaccaagtct
      721 taacctcttg gttaggctca gggctgcgcc gcagttccgc ccgccgctga tgctcctggt
      781 aacttcttga cctttcattt tagagttttg gggttttttt ttcctccctg ttatacgata
      841 tacttgatga ctggagccta tttatagata taacagatat tttaaacctt cctaaaacca
      901 tgtccatgtc tgaaggaaaa cacaacttca tacagtcctt ggaacggaca aaagcagatc
      961 ttcctatttc gtacaaagca gtcgagaaag tacttctggg gtgggtgtgc tccttgtatt
     1021 cactctgccc ctacactgag gacttcagag aggctcgatt gaactggcat aagcaaacaa
     1081 attccataag atgaagttaa aatactgatg agataatcgg actgttagaa agacacttag
     1141 aaattaccac ttcaactaaa tgtgcgttgt gaccaaacgg aaacttctac gcgatttagg
     1201 ttttacccca ttattattta tttagagtat acgtcgttca aggagctaga ggcaaaatgc
     1261 tgactgtgca tgagagtagg ggaggtgatg aacgctggca ccatgcctca aaggaagggt
     1321 ggctgccagg cagcaccttc tgagctttga aaggagcctg ctggggagac agaaggctgg
     1381 tggcagcagg cagcagggac caaagcctcg cctcctgcca gcaggtgtcc aaccaataaa
     1441 gagaagaaac tgagggttga gtgcctcaaa cctccgttgt gggtgcagta ggaggcgagg
     1501 cctgcaaagg tcccaaaaga attactctga gtgccagctg cccctgtaat cctgatgtgc
     1561 cttagaaaaa tggtggactt gtttaggaat ctggacttgt acatttattc tacctttatc
     1621 tgaggaaaga aagcagatca tctgagctgt tctgtcccac tgcccctaat ggagtctcaa
     1681 ccctatcacg caagatcgag gctcttcggg tacctgacaa ccagcactga taaaacctgt
     1741 ggctgtttcc atagcaagct ttggccacag tctggagact ttagtggagt gtggaaggct
     1801 cacaaaggtc ccctggagtc acgcctagta ccactgacaa ggcccgtcct tccagccttc
     1861 aagctggaga ggaagaacct ggctgcaggg gtctggggtt gtgtgttcgt gaagggagga
     1921 ccaggaattt tacagtgatg gatggccctg ggttaggatg ttctgcttgg gaggagggga
     1981 aggactgggc tatgctcagc agtcccagtc aactccagga aaactgctgt ccttggacct
     2041 tcactggtcc atctgctcca aataaagcaa aaaagatgat attgcatggg actgcctatt
     2101 gatacctatt gacattcctc tgccctgtgt ctcctgggaa aatggatacc agaaaggttt
     2161 tgttttgttt tgttttgaga caaaaccatc actaggtagt cccaacagac ctaatagaaa
     2221 atagacttgc tattctccaa ggatggcctt agactcacaa aggtccactt taatcccaag
     2281 tgctgggatt aaagacatac agcacaatgc
//
