LOCUS       NM_001031660            1168 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus methionine sulfoxide reductase B2 (Msrb2), mRNA;
            nuclear gene for mitochondrial product.
ACCESSION   NM_001031660 XM_341571
VERSION     NM_001031660.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1168)
  AUTHORS   Lee,B.C., Peterfi,Z., Hoffmann,F.W., Moore,R.E., Kaya,A.,
            Avanesov,A., Tarrago,L., Zhou,Y., Weerapana,E., Fomenko,D.E.,
            Hoffmann,P.R. and Gladyshev,V.N.
  TITLE     MsrB1 and MICALs regulate actin assembly and macrophage function
            via reversible stereoselective methionine oxidation
  JOURNAL   Mol Cell 51 (3), 397-404 (2013)
   PUBMED   23911929
REFERENCE   2  (bases 1 to 1168)
  AUTHORS   Kim,H.Y. and Gladyshev,V.N.
  TITLE     Methionine sulfoxide reduction in mammals: characterization of
            methionine-R-sulfoxide reductases
  JOURNAL   Mol Biol Cell 15 (3), 1055-1064 (2004)
   PUBMED   14699060
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC098953.1.
            
            [WARNING] On Apr 15, 2024 this sequence was replaced by
            NM_001031660.2.
            
            On Aug 12, 2005 this sequence version replaced XM_341571.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC098953.1, CO397714.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132262, SAMD00132264
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1168
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17q12.3"
     gene            1..1168
                     /gene="Msrb2"
                     /gene_synonym="Mrsb"
                     /note="methionine sulfoxide reductase B2"
                     /db_xref="GeneID:361286"
                     /db_xref="RGD:1306026"
     exon            1..112
                     /gene="Msrb2"
                     /gene_synonym="Mrsb"
                     /inference="alignment:Splign:2.1.0"
     CDS             19..543
                     /gene="Msrb2"
                     /gene_synonym="Mrsb"
                     /EC_number="1.8.4.12"
                     /EC_number="1.8.4.14"
                     /note="methionine-R-sulfoxide reductase B2, mitochondrial"
                     /codon_start=1
                     /product="methionine-R-sulfoxide reductase B2,
                     mitochondrial precursor"
                     /protein_id="NP_001026830.1"
                     /db_xref="GeneID:361286"
                     /db_xref="RGD:1306026"
                     /translation="MARLLRALRGLPWLEAPGRARGCAGSGRGDTGSLIKSKLSLSKA
                     DWQKKLTPEQFYVTREKGTEAPFSGMYLKNKETGMYHCVCCDSPLFSSEKKYCSGTGW
                     PSFSEAHGTKGSDESHTGILRRLDTSLGCPRMEVVCKQCEAHLGHVFPDGPDPTGQRF
                     CINSVALKFKPSKP"
     exon            113..213
                     /gene="Msrb2"
                     /gene_synonym="Mrsb"
                     /inference="alignment:Splign:2.1.0"
     exon            214..290
                     /gene="Msrb2"
                     /gene_synonym="Mrsb"
                     /inference="alignment:Splign:2.1.0"
     exon            291..438
                     /gene="Msrb2"
                     /gene_synonym="Mrsb"
                     /inference="alignment:Splign:2.1.0"
     exon            439..1141
                     /gene="Msrb2"
                     /gene_synonym="Mrsb"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cccgttggtg gcagagtcat ggcgcgtctg ctgcgagcgc tgcggggtct gccttggctg
       61 gaggcgcctg ggcgagctcg gggttgcgcg ggatcgggac gcggggacac agggtctctt
      121 atcaagtcca agctctctct aagcaaggca gactggcaga agaaactgac ccctgagcaa
      181 ttctacgtca ccagagagaa aggaactgaa gcgcctttca gtggaatgta tttgaaaaac
      241 aaggagacag ggatgtacca ttgcgtgtgc tgtgatagcc cactcttcag ttctgagaag
      301 aagtactgtt ctggcaccgg ttggccttcg ttttctgagg ctcacggcac caaaggctca
      361 gatgaaagtc acacagggat cctgaggcgc ctggacactt ccttaggatg tcctcgcatg
      421 gaggtggtct gcaaacagtg tgaagctcac cttggccatg tgtttcctga tggacccgat
      481 cccactggac aaaggttttg catcaacagc gtggccctga agttcaaacc aagcaagccc
      541 tgactgtctg cagggggcct gtgctttgcc cctgcttgtg gagccacggt tctgtaattc
      601 tgttgaatcc cttgctttag ttgctgaaag tttaggtgaa ggttgttcct ggccaacagg
      661 ggagtcagag cttcttagtc acctgacttc cacttgggct gtgggatttc aactggctgc
      721 ccagactctg ggtgagacca cagggtggga cccaggcagg atttccacgg gttcatgggc
      781 tgatgagggt tcccaaagct cctgaaggga acctgagttg gccatctcgg ttcattcctt
      841 catgggcgta tacagatgag ggcccaaggg ggagagaaag gaacagatgg gctggaccag
      901 atgagagatc ccagtgttgg agaggaggat gggagtggcc gagcatggga acacattcag
      961 ggatggatga gtctgtggtt tcttatccaa aactccactg actcaacctt aaaactcaca
     1021 agtgggatcc atgcggactg agtcaatctg agtgactgtg aataatgaat gctctccctc
     1081 aactctttgt cacaacacta aacttcaaaa tactcaaata aaatattgag gtcaatgttt
     1141 aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//
