LOCUS       NM_001014111            2270 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus MSL complex subunit 3 (Msl3), mRNA.
ACCESSION   NM_001014111 XM_228915
VERSION     NM_001014111.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2270)
  AUTHORS   Basilicata,M.F., Bruel,A.L., Semplicio,G., Valsecchi,C.I.K.,
            Aktas,T., Duffourd,Y., Rumpf,T., Morton,J., Bache,I.,
            Szymanski,W.G., Gilissen,C., Vanakker,O., Ounap,K., Mittler,G., van
            der Burgt,I., El Chehadeh,S., Cho,M.T., Pfundt,R., Tan,T.Y.,
            Kirchhoff,M., Menten,B., Vergult,S., Lindstrom,K., Reis,A.,
            Johnson,D.S., Fryer,A., McKay,V., Fisher,R.B., Thauvin-Robinet,C.,
            Francis,D., Roscioli,T., Pajusalu,S., Radtke,K., Ganesh,J.,
            Brunner,H.G., Wilson,M., Faivre,L., Kalscheuer,V.M., Thevenon,J.
            and Akhtar,A.
  CONSRTM   DDD Study
  TITLE     De novo mutations in MSL3 cause an X-linked syndrome marked by
            impaired histone H4 lysine 16 acetylation
  JOURNAL   Nat Genet 50 (10), 1442-1451 (2018)
   PUBMED   30224647
REFERENCE   2  (bases 1 to 2270)
  AUTHORS   Kim,D., Blus,B.J., Chandra,V., Huang,P., Rastinejad,F. and
            Khorasanizadeh,S.
  TITLE     Corecognition of DNA and a methylated histone tail by the MSL3
            chromodomain
  JOURNAL   Nat Struct Mol Biol 17 (8), 1027-1029 (2010)
   PUBMED   20657587
REFERENCE   3  (bases 1 to 2270)
  AUTHORS   Cai,Y., Jin,J., Swanson,S.K., Cole,M.D., Choi,S.H., Florens,L.,
            Washburn,M.P., Conaway,J.W. and Conaway,R.C.
  TITLE     Subunit composition and substrate specificity of a MOF-containing
            histone acetyltransferase distinct from the male-specific lethal
            (MSL) complex
  JOURNAL   J Biol Chem 285 (7), 4268-4272 (2010)
   PUBMED   20018852
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC086548.1.
            
            [WARNING] On Oct 24, 2024 this sequence was replaced by
            NM_001014111.2.
            
            On Apr 20, 2005 this sequence version replaced XM_228915.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC086548.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132262, SAMD00132263
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2270
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq13"
     gene            1..2270
                     /gene="Msl3"
                     /gene_synonym="Msl31; Msl3l1"
                     /note="MSL complex subunit 3"
                     /db_xref="GeneID:317464"
                     /db_xref="RGD:1549763"
     exon            1..108
                     /gene="Msl3"
                     /gene_synonym="Msl31; Msl3l1"
                     /inference="alignment:Splign:2.1.0"
     CDS             101..1501
                     /gene="Msl3"
                     /gene_synonym="Msl31; Msl3l1"
                     /note="male-specific lethal-3 homolog 1"
                     /codon_start=1
                     /product="male-specific lethal 3 homolog"
                     /protein_id="NP_001014133.1"
                     /db_xref="GeneID:317464"
                     /db_xref="RGD:1549763"
                     /translation="MPSWDRWAAEDHVLHDTDENRRLQRKLAKKAIARLRGTGKKKRR
                     CRLPGVDSVLKSVPVKEKTKNDENSISSTCHESCGEKNGGIKEHRQRRIKVKTKGKKK
                     VLSLRSRKDMDERTITIEIPEVLKKQLEDDCYYINRRKRLVKLPCQTNIITILESYVK
                     HFAINAAFSANERPRHHHAMMHAHMNVHYVPAEKNVDLCKEMVDGLRITFDYTLPLVL
                     LYPYEQTQYKRVTSSKFFLPIKESTTTTNRSQEELSPSPPLLNPSTPQSTESQPPTGE
                     PATPKRRKAEPEALQSLRRSTRHSTNCDRLSESSSSPQPKRRQQDTSTSMPKLFLHLE
                     KKTPVHSRSSSPIPLTPSKDGSAVFAGFEGRRTNEINEVLSWKLVPDNYPPGDQPPPP
                     SYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAYV
                     AACEAHYSTKNPRAIY"
     exon            109..204
                     /gene="Msl3"
                     /gene_synonym="Msl31; Msl3l1"
                     /inference="alignment:Splign:2.1.0"
     exon            205..305
                     /gene="Msl3"
                     /gene_synonym="Msl31; Msl3l1"
                     /inference="alignment:Splign:2.1.0"
     exon            306..397
                     /gene="Msl3"
                     /gene_synonym="Msl31; Msl3l1"
                     /inference="alignment:Splign:2.1.0"
     exon            398..523
                     /gene="Msl3"
                     /gene_synonym="Msl31; Msl3l1"
                     /inference="alignment:Splign:2.1.0"
     exon            524..684
                     /gene="Msl3"
                     /gene_synonym="Msl31; Msl3l1"
                     /inference="alignment:Splign:2.1.0"
     exon            685..843
                     /gene="Msl3"
                     /gene_synonym="Msl31; Msl3l1"
                     /inference="alignment:Splign:2.1.0"
     exon            844..1106
                     /gene="Msl3"
                     /gene_synonym="Msl31; Msl3l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1107..1216
                     /gene="Msl3"
                     /gene_synonym="Msl31; Msl3l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1217..1316
                     /gene="Msl3"
                     /gene_synonym="Msl31; Msl3l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1317..1401
                     /gene="Msl3"
                     /gene_synonym="Msl31; Msl3l1"
                     /inference="alignment:Splign:2.1.0"
     exon            1402..2246
                     /gene="Msl3"
                     /gene_synonym="Msl31; Msl3l1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagcaaatga gcgcgagcaa gggcatgaaa tttcaattcc actctgggga gaaagtgctg
       61 tgcttcgagc ctgaccccac caaggcgcga gtgctgtacg atgccaagtt gggatagatg
      121 ggcggctgaa gatcatgtgc tacatgatac agatgaaaac cgaagattac agcgaaaatt
      181 ggccaaaaag gcaatagctc gcctgagagg cacaggaaaa aagaagaggc gctgtaggtt
      241 gcctggtgtt gactctgtct taaaaagtgt gccagtcaaa gaaaaaacta aaaatgacga
      301 aaattcaata agcagcacct gtcatgagag ctgtggagaa aagaatggag gaataaaaga
      361 acaccgacaa cgccgtatta aagtaaagac taaagggaag aaaaaggtat tgtctctgcg
      421 ctcaagaaag gatatggatg agaggacaat cactatagag atccctgaag ttctcaagaa
      481 gcagcttgag gatgactgtt actatatcaa caggagaaag cggttagtga aacttccatg
      541 ccagaccaac atcataacaa ttttggaatc ctatgtgaaa cattttgcta ttaatgcagc
      601 cttttcagcc aacgagaggc ctcgtcacca tcatgccatg atgcatgcgc acatgaatgt
      661 tcactatgtc ccagcagaga agaatgttga cctttgtaag gagatggtgg atggattacg
      721 aataactttt gattatactc tcccattggt tttgctttat ccatatgaac aaactcaata
      781 taaaagggtg acatcgtcaa aattctttct tcctattaag gaaagtacca cgacaactaa
      841 taggagtcag gaggagctgt ctcctagccc acctttgttg aatccatcca caccacagtc
      901 tacagagagt cagccaccta ctggtgaacc agccaccccc aagaggcgca aagcagagcc
      961 agaggcactg cagtctctca ggaggtccac gcggcacagc accaactgtg acaggctgtc
     1021 tgaaagcagc tcgtcacctc agccgaagcg caggcaacag gacacatcca ccagcatgcc
     1081 gaagctgttt ctgcacttgg aaaagaagac acctgtgcat agcagatcat cttcccccat
     1141 tcctctgact ccaagtaagg atgggagtgc tgtattcgct ggcttcgaag ggagaagaac
     1201 caatgaaatc aatgaggtac tgtcttggaa acttgtgcct gacaattacc caccaggaga
     1261 ccagccacct cccccttcat acatttatgg tgcacagcat ttgctcagat tatttgtgaa
     1321 acttccagaa atccttggga agatgtcctt ctctgagaag aatctgaagg ctttactgaa
     1381 gcactttgat ctctttctga ggtttttagc agaataccat gatgacttct tcccggagtc
     1441 ggcttatgtt gctgcctgtg aggcacacta cagcaccaag aaccccaggg caatttatta
     1501 aacttttgat ggttttgaga aaacagctgc actatgtggc tttctatttt aggttccagg
     1561 tgaagtgtta atgagatgct agccctaccc tgggggtact ctgacagaaa caggctctgt
     1621 ttttttgagt tcttcacata ctattatttc tgttaagaat tactttctga gctcagcatg
     1681 gtggtccatg tctatgggga gggggtcggt ttaattaatt aattaatggt ttttaaaaac
     1741 tgtaatgatg acttcctggg tgcctgaacg tattccaaag taacactgct acacaagctc
     1801 tgtgtgccgg caggataaaa acagccatag ctgtcttcat agggatacat tcacgactgt
     1861 atacttaggt taaacatggt tccagtagac agcaccgttg gttgttagca agagccacat
     1921 ggtttgatta tttgttaatg ttaaacaaag atggttttga aaactgtttt ctgttcaaca
     1981 gatcttagtc ggtgcttgga agccgcaaag cactctcaaa gtatttctga gggaattgat
     2041 attgatggca aacgagaaca tgcagctatg cattgcttgt agcagttccc tttctcagaa
     2101 acattatttt tgttgctcta aataaagcat tgcctgtctt gtttgagatt ttacagccat
     2161 actctgctat gtaatgttat agttcctttt tctatgaaat gttattttgg gtgatctaaa
     2221 taaagctttg ccagttttgt ttgaaaaaaa aaaaaaaaaa aaaaaaaaaa
//
