LOCUS       XM_039112994            3022 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus mutS homolog 2 (Msh2), transcript
            variant X1, mRNA.
ACCESSION   XM_039112994
VERSION     XM_039112994.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051341.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039112994.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3022
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..3022
                     /gene="Msh2"
                     /note="mutS homolog 2; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 52 ESTs, 1 long SRA read,
                     1 Protein, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 115 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:81709"
                     /db_xref="RGD:620786"
     CDS             97..2814
                     /gene="Msh2"
                     /codon_start=1
                     /product="DNA mismatch repair protein Msh2 isoform X1"
                     /protein_id="XP_038968922.1"
                     /db_xref="GeneID:81709"
                     /db_xref="RGD:620786"
                     /translation="MAVQPKETLQLEGAAEVGFVRFFEGMPEKPSTTVRLFDRGDFYT
                     AHGEDALLAAREVFKTQGVIKYMGPAGAKTLQTVVLSKMNFESFVKDLLLVRHYRVEV
                     YKNKAGNKASKENDWYLAYKASPGNLSQFEDILFGNNDMSTSIGIMGIKLSTVDGQRQ
                     VGVGYVDSTQRKLGLCEFPDNDQFSNLEALLIQIGPKECILPGGETAGDMGKLRQVIQ
                     RGGILITERKRIDFSTKDIYQDLNRLLKGRKGEQMNSAVLPEMENQVAVSSLSAVIKF
                     LELLSDDSNFGQFELATFDFSQYMKLDMAAVRALNLFQGSVEDTTGSQSLAALLNKCK
                     TAQGQRLVSQWIKQPLMDKNRIEERLNLVEAFVEDSELRQSLQEDLLRRFPDLNRLAK
                     KFQRQAANLQDCYRLYQGVNQLPNVIQALEKYQGRHQALLLAVFVTPLTDLRSDFSKF
                     QEMIETTLDMDQVENHEFLVKPSFDPNLSELREVMDGLEKKMQSTLISAARGLGLDPG
                     KQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFSTVDIQKNGVKFTNSELSSLNEEYTKN
                     KGEYEEAQDAIVKEIVNISSAPVPYVRPVILEKGKGRIILKASRHACVEVQDDVAFIP
                     NDVHFEKDKQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILA
                     RVGAGDSQLKGVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISE
                     YIATKIGAFCMFATHFHELTALASQIPTVNNLHVTALTTEETLTMLYQVKTGVCDQSF
                     GIHVAELANFPRHVIECAKQKALELEEFQSIGTSQGHDETQPAAKRRCLEREQGEKII
                     LEFLSKVKQVPFTDLSEESVSVKLKQLKAEVLAKNNSFVNEIISRVKAP"
ORIGIN      
        1 ggacgcggtt taggggcgag gttggggagg cgggaaacga cccggcgagc gcagggtccg
       61 gctgtactct cttgggttgt gtggcgcgtt tcggaaatgg cggtgcagcc taaggagacg
      121 ctgcagttgg agggcgcggc cgaggtgggc ttcgtacgct tctttgaggg catgccggag
      181 aagccgagca ccacggtgcg cctcttcgac cgcggcgact tttacaccgc gcacggcgag
      241 gacgcgctgc tggcggcccg cgaggtgttc aagacccaag gcgtgatcaa gtacatgggg
      301 ccggcagggg caaagaccct gcagactgtt gtgctgagta agatgaattt tgagtctttc
      361 gtgaaagatc ttcttctggt tcgtcactat agagttgaag tttataagaa taaagctgga
      421 aataaggcat ctaaggagaa cgactggtat ttggcatata aggcttctcc tggcaatctt
      481 tctcagtttg aagacatcct gtttggtaac aatgacatgt ccacttccat tggcattatg
      541 ggtattaaac tgtctacggt tgatggtcag agacaggttg gagttgggta tgtggattcc
      601 acccagagaa agctaggatt gtgtgagttc cctgacaacg atcagttctc caatctcgag
      661 gctcttctga ttcagattgg accaaaggaa tgcattttac caggcggaga gactgctgga
      721 gacatgggga aactgaggca ggttatacag agaggaggga ttctgatcac agaaagaaag
      781 agaatcgact tttccacaaa agacatctac caggatctca accggttact gaaaggcaga
      841 aaaggagagc agatgaacag cgctgtctta ccagagatgg agaatcaggt tgcagtttca
      901 tcgttgtctg cagtgatcaa gttcctagaa ctcttatcag atgattcgaa ttttgggcag
      961 tttgaactgg cgacttttga cttcagccag tacatgaagt tagacatggc ggcagttaga
     1021 gccctcaacc ttttccaggg ttctgttgaa gacaccacag gctctcagtc tctggctgca
     1081 ttattgaata aatgcaaaac tgctcaagga caaaggctgg ttagccagtg gatcaaacag
     1141 ccgctcatgg ataaaaacag gattgaagag agattaaatt tagtggaagc ttttgttgaa
     1201 gattcagaat tgaggcagag tctacaggag gatttacttc gccgatttcc agatcttaac
     1261 cggcttgcca agaaatttca gagacaagca gcgaatttac aagattgtta ccgactgtat
     1321 cagggtgtga accagcttcc caacgtcatc caggctctgg agaaatacca aggaagacac
     1381 caggcattgt tgttggcagt ttttgtgact cctcttactg atcttcgttc tgatttttca
     1441 aaatttcaag aaatgataga aacgacttta gatatggatc aggtggagaa ccacgaattc
     1501 cttgtaaaac cttcatttga tcctaacctg agtgagctaa gagaagtcat ggatggtctg
     1561 gagaagaaga tgcagtccac cttaataagt gcagcgcggg gtcttggatt ggaccctggc
     1621 aaacagatta aattggactc cagtgcacag tttgggtatt actttcgtgt aacctgcaag
     1681 gaagagaaag tcctccgcaa caacaagaac ttcagcaccg tggatatcca gaagaatggc
     1741 gttaaattca ccaacagtga attgtcttct ttaaatgaag aatacactaa gaacaaagga
     1801 gagtatgagg aggcccagga tgccattgtt aaagaaatcg tcaatatttc ctcagctcct
     1861 gtcccctacg tgcgaccggt catcttggag aaaggaaaag gaagaattat attgaaagcc
     1921 tccaggcatg cttgtgttga agttcaagat gacgttgcat ttattccaaa cgatgtgcac
     1981 tttgaaaaag ataaacagat gttccacatc attactggtc ccaatatggg aggaaagtca
     2041 acatacatcc gtcagacggg ggtgattgtg ctcatggccc aaattgggtg ttttgtgccg
     2101 tgtgagtcag cagaggtgtc cattgtggat tgcatcttgg ctcgagtcgg ggctggtgac
     2161 agtcaactga aaggcgtctc cacattcatg gctgaaatgc tggaaactgc ttctatcctc
     2221 aggtcggcaa ccaaagattc cttaataatc attgatgagc tgggaagagg aacctctaca
     2281 tacgacggct ttgggttagc atgggccata tcggagtaca tcgcaacgaa gattggtgcc
     2341 ttttgcatgt ttgccaccca ttttcatgaa cttaccgctt tggccagtca gataccaacc
     2401 gttaacaatc tccacgtcac agcgctgact accgaagaga ccctgactat gctttaccaa
     2461 gtgaaaacag gtgtctgtga tcagagtttc gggattcatg tggctgaact cgctaatttc
     2521 cctaggcatg tgatagagtg cgccaagcag aaggctctgg agcttgagga gtttcagagc
     2581 attgggacct cacagggaca cgatgaaacc cagccagctg caaagaggcg ctgcctggaa
     2641 agagagcaag gtgagaagat tattctggag ttcctgtcca aggtcaagca agtgcccttc
     2701 actgacttgt cggaggagag cgtctcagtg aagctgaagc aactgaaagc tgaggtgctg
     2761 gcgaagaaca acagctttgt aaatgaaatc atctcacggg taaaggctcc gtgagaggac
     2821 agtggagcga agccagtagg gagagctcgc ccttaccctg ctgtttcctg tagtacttaa
     2881 caccagaacc cggggagcag tgtgctgaag tatttagtga tacttgaaac atgacggtct
     2941 atagctgagt accgtttaaa tgggcatgga caactttgag cactatgctg aattttataa
     3001 ataaaatcat gtagtttcta ga
//
