LOCUS       NM_001191754            1372 bp    mRNA    linear   ROD 07-JAN-2025
DEFINITION  Rattus norvegicus musculin (Msc), mRNA.
ACCESSION   NM_001191754 XM_232587
VERSION     NM_001191754.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1372)
  AUTHORS   Vanni,A., Carnasciali,A., Mazzoni,A., Russo,E., Farahvachi,P.,
            Gloria,L.D., Ramazzotti,M., Lamacchia,G., Capone,M., Salvati,L.,
            Calosi,L., Bani,D., Liotta,F., Cosmi,L., Amedei,A., Ballerini,C.,
            Maggi,L. and Annunziato,F.
  TITLE     Musculin does not modulate the disease course of Experimental
            Autoimmune Encephalomyelitis and DSS colitis
  JOURNAL   Immunol Lett 255, 21-31 (2023)
   PUBMED   36848960
REFERENCE   2  (bases 1 to 1372)
  AUTHORS   Yan,J., Yu,J., Yuan,S., Tang,W., Ma,W., Yang,X., Liu,Y., Liang,H.,
            Zhong,X., Shao,J., Cao,Y., Mao,C., Near,R. and Gao,W.
  TITLE     Musculin is highly enriched in Th17 and IL-22-producing ILC3s and
            restrains pro-inflammatory cytokines in murine colitis
  JOURNAL   Eur J Immunol 51 (4), 995-998 (2021)
   PUBMED   33448336
REFERENCE   3  (bases 1 to 1372)
  AUTHORS   Tarantino,C., Paolella,G., Cozzuto,L., Minopoli,G., Pastore,L.,
            Parisi,S. and Russo,T.
  TITLE     miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic
            stem cells
  JOURNAL   FASEB J 24 (9), 3255-3263 (2010)
   PUBMED   20439489
REFERENCE   4  (bases 1 to 1372)
  AUTHORS   Craig,D.W., Millis,M.P. and DiStefano,J.K.
  TITLE     Genome-wide SNP genotyping study using pooled DNA to identify
            candidate markers mediating susceptibility to end-stage renal
            disease attributed to Type 1 diabetes
  JOURNAL   Diabet Med 26 (11), 1090-1098 (2009)
   PUBMED   19929986
REFERENCE   5  (bases 1 to 1372)
  AUTHORS   Nishiyama,A., Xin,L., Sharov,A.A., Thomas,M., Mowrer,G., Meyers,E.,
            Piao,Y., Mehta,S., Yee,S., Nakatake,Y., Stagg,C., Sharova,L.,
            Correa-Cerro,L.S., Bassey,U., Hoang,H., Kim,E., Tapnio,R., Qian,Y.,
            Dudekula,D., Zalzman,M., Li,M., Falco,G., Yang,H.T., Lee,S.L.,
            Monti,M., Stanghellini,I., Islam,M.N., Nagaraja,R., Goldberg,I.,
            Wang,W., Longo,D.L., Schlessinger,D. and Ko,M.S.
  TITLE     Uncovering early response of gene regulatory networks in ESCs by
            systematic induction of transcription factors
  JOURNAL   Cell Stem Cell 5 (4), 420-433 (2009)
   PUBMED   19796622
REFERENCE   6  (bases 1 to 1372)
  AUTHORS   Lu,J.R., Bassel-Duby,R., Hawkins,A., Chang,P., Valdez,R., Wu,H.,
            Gan,L., Shelton,J.M., Richardson,J.A. and Olson,E.N.
  TITLE     Control of facial muscle development by MyoR and capsulin
  JOURNAL   Science 298 (5602), 2378-2381 (2002)
   PUBMED   12493912
REFERENCE   7  (bases 1 to 1372)
  AUTHORS   Lu,J., Webb,R., Richardson,J.A. and Olson,E.N.
  TITLE     MyoR: a muscle-restricted basic helix-loop-helix transcription
            factor that antagonizes the actions of MyoD
  JOURNAL   Proc Natl Acad Sci U S A 96 (2), 552-557 (1999)
   PUBMED   9892671
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Aug 29, 2022 this sequence version replaced NM_001191754.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360186.2392676.1,
                                           SRR26643429.18611.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-766               JAXUCZ010000005.1  9334280-9335045
            767-1372            JAXUCZ010000005.1  9335780-9336385
FEATURES             Location/Qualifiers
     source          1..1372
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q11"
     gene            1..1372
                     /gene="Msc"
                     /note="musculin"
                     /db_xref="GeneID:312897"
                     /db_xref="RGD:1305496"
     exon            1..766
                     /gene="Msc"
                     /inference="alignment:Splign:2.1.0"
     CDS             242..853
                     /gene="Msc"
                     /codon_start=1
                     /product="musculin"
                     /protein_id="NP_001178683.1"
                     /db_xref="GeneID:312897"
                     /db_xref="RGD:1305496"
                     /translation="MSTGSVSDPEDTEMRGLQRVYPAPASKRPPLLRPERSYASPSDN
                     SSAEEEDPDGEEEPGTVGAAGGCKRKRPRGADASGAGGGAGSTGKKALPPKGSAAECK
                     QSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLL
                     QEDRYEDSYVHPVNLTWPFVVSGRPDSDTKDVSAANRLCGTSA"
     exon            767..1372
                     /gene="Msc"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcggctgtac ttctggatcc ggagtcaagt tcagcagagc cctgggctgg agggtcagca
       61 gccaattgcg cccgctccag gctcccagat cactggggag ctgcagtgcc gcaaacccgg
      121 gtctctggat ctcccctgag ctctcccacg ccctgtcctc tgtcagagag aagaagccgg
      181 agagggcgag actggccggg gcggagaaag gcgggcgcgc gtgggcgcca gggaataggc
      241 gatgtccacc ggctcggtga gtgaccccga agacacggag atgcgggggc tgcagcgggt
      301 ctacccggcc cccgcctcca agaggccacc cctgctccgc ccggagcgca gttacgcctc
      361 gcccagcgac aactcttcgg cggaggagga ggaccccgac ggcgaagagg agccgggcac
      421 cgtgggagcc gcgggaggct gcaagagaaa gcggccccgt ggggctgacg ccagcggcgc
      481 aggtggcggt gcgggcagca ccgggaagaa ggcgctcccg cccaagggct cggccgccga
      541 gtgcaagcag tcacagcgga acgcggccaa cgcccgcgaa cgcgcccgga tgcgcgtgct
      601 gagcaaagct ttctccagac tcaagaccag cctgccttgg gtgccgccgg acaccaagct
      661 ttccaaactg gacacgctgc gtttggcttc cagctacatc gcgcacctgc gccagctgct
      721 gcaggaggac cgctacgagg atagctatgt gcaccccgtg aacctgacgt ggccattcgt
      781 ggtctctgga cgcccagact ctgataccaa agatgtttct gcagccaaca ggctttgtgg
      841 aacttcagct tagatggaca gcaacactgc tggatggatt gtgttaaatg caaaggactg
      901 ggccaaggaa gtcccatcga ttccggacct tctcctttcc ctgtgtttgt gaacaagaca
      961 ggtgacaagt gtggttgccc tcctggaaca caggtggcca tggctacttg aatcagttca
     1021 aaaacctgta gccaaagaga gcccagtttt ggggaaaggg gatatctggg gattcagctc
     1081 cttcccaccc acactgtccc tgaagtcttt tcttactgcc tatttgggga tacacacttc
     1141 acccctgtaa tcaggtcacc atgccacagc acagcttctg tttttccagg gttgcactgt
     1201 tcttcctggt ccaaggactg cacatgatgg gcagctgggg ctggggctgg ggctggggct
     1261 ggagctggtc tctattatac tggtttctac ccagtgcatg gtgcttagtg gtcctggcaa
     1321 tgctgcagta ccatggtaac taacatatgt aaataaattt atttttttat ga
//
