LOCUS       NM_001399452            1560 bp    mRNA    linear   ROD 21-MAY-2024
DEFINITION  Rattus norvegicus membrane spanning 4-domains A1 (Ms4a1), mRNA.
ACCESSION   NM_001399452 XM_006231089
VERSION     NM_001399452.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1560)
  AUTHORS   Archambaud,C., Nahori,M.A., Soubigou,G., Becavin,C., Laval,L.,
            Lechat,P., Smokvina,T., Langella,P., Lecuit,M. and Cossart,P.
  TITLE     Impact of lactobacilli on orally acquired listeriosis
  JOURNAL   Proc Natl Acad Sci U S A 109 (41), 16684-16689 (2012)
   PUBMED   23012479
REFERENCE   2  (bases 1 to 1560)
  AUTHORS   Bohm,D., Keller,K., Pieter,J., Boehm,N., Wolters,D., Siggelkow,W.,
            Lebrecht,A., Schmidt,M., Kolbl,H., Pfeiffer,N. and Grus,F.H.
  TITLE     Comparison of tear protein levels in breast cancer patients and
            healthy controls using a de novo proteomic approach
  JOURNAL   Oncol Rep 28 (2), 429-438 (2012)
   PUBMED   22664934
REFERENCE   3  (bases 1 to 1560)
  AUTHORS   Kim,Y., Kim,K., Park,D., Eom,S., Park,H., Lee,H., Lee,Y.S.,
            Choe,J., Hahn,J.H., Kim,Y.M., Ro,J.Y. and Jeoung,D.
  TITLE     Integrin alpha(5) interacts with EGFR, is necessary for
            FcvarepsilonRI signaling and is necessary for allergic inflammation
            in relation with angiogenesis
  JOURNAL   Mol Immunol 48 (8), 1035-1045 (2011)
   PUBMED   21349584
REFERENCE   4  (bases 1 to 1560)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   5  (bases 1 to 1560)
  AUTHORS   Robak,T., Jamroziak,K. and Robak,P.
  TITLE     Current and emerging treatments for chronic lymphocytic leukaemia
  JOURNAL   Drugs 69 (17), 2415-2449 (2009)
   PUBMED   19911856
REFERENCE   6  (bases 1 to 1560)
  AUTHORS   Uchida,J., Lee,Y., Hasegawa,M., Liang,Y., Bradney,A., Oliver,J.A.,
            Bowen,K., Steeber,D.A., Haas,K.M., Poe,J.C. and Tedder,T.F.
  TITLE     Mouse CD20 expression and function
  JOURNAL   Int Immunol 16 (1), 119-129 (2004)
   PUBMED   14688067
REFERENCE   7  (bases 1 to 1560)
  AUTHORS   Li,H., Ayer,L.M., Lytton,J. and Deans,J.P.
  TITLE     Store-operated cation entry mediated by CD20 in membrane rafts
  JOURNAL   J Biol Chem 278 (43), 42427-42434 (2003)
   PUBMED   12920111
REFERENCE   8  (bases 1 to 1560)
  AUTHORS   Radounikli,A., Stahl,R.A., Bergmann,L., Schoeppe,W. and Thaiss,F.
  TITLE     Characterization of the mononuclear cell infiltrate in the
            glomerulus of rats with glomerulonephritis
  JOURNAL   Nephrol Dial Transplant 10 (2), 185-190 (1995)
   PUBMED   7538648
REFERENCE   9  (bases 1 to 1560)
  AUTHORS   Bubien,J.K., Zhou,L.J., Bell,P.D., Frizzell,R.A. and Tedder,T.F.
  TITLE     Transfection of the CD20 cell surface molecule into ectopic cell
            types generates a Ca2+ conductance found constitutively in B
            lymphocytes
  JOURNAL   J Cell Biol 121 (5), 1121-1132 (1993)
   PUBMED   7684739
REFERENCE   10 (bases 1 to 1560)
  AUTHORS   Tedder,T.F., Boyd,A.W., Freedman,A.S., Nadler,L.M. and
            Schlossman,S.F.
  TITLE     The B cell surface molecule B1 is functionally linked with B cell
            activation and differentiation
  JOURNAL   J Immunol 135 (2), 973-979 (1985)
   PUBMED   3925015
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Jan 7, 2022 this sequence version replaced XM_006231089.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ225563.1, FQ226425.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676786, SAMN16676810
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-94                JAXUCZ010000001.1  217343354-217343447 c
            95-268              JAXUCZ010000001.1  217338400-217338573 c
            269-388             JAXUCZ010000001.1  217337892-217338011 c
            389-448             JAXUCZ010000001.1  217336322-217336381 c
            449-685             JAXUCZ010000001.1  217334459-217334695 c
            686-787             JAXUCZ010000001.1  217333302-217333403 c
            788-1560            JAXUCZ010000001.1  217331274-217332046 c
FEATURES             Location/Qualifiers
     source          1..1560
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..1560
                     /gene="Ms4a1"
                     /gene_synonym="Cd20"
                     /note="membrane spanning 4-domains A1"
                     /db_xref="GeneID:309217"
                     /db_xref="RGD:1311999"
     exon            1..94
                     /gene="Ms4a1"
                     /gene_synonym="Cd20"
                     /inference="alignment:Splign:2.1.0"
     exon            95..268
                     /gene="Ms4a1"
                     /gene_synonym="Cd20"
                     /inference="alignment:Splign:2.1.0"
     CDS             110..1006
                     /gene="Ms4a1"
                     /gene_synonym="Cd20"
                     /note="membrane-spanning 4-domains, subfamily A, member 1"
                     /codon_start=1
                     /product="B-lymphocyte antigen CD20"
                     /protein_id="NP_001386381.1"
                     /db_xref="GeneID:309217"
                     /db_xref="RGD:1311999"
                     /translation="MTTPRNSVSGPFPTEPTKGPLAMQPAQKVIPRRPSSLVGPTQSF
                     FMRESKALGAVQIMNGLFHISLGGLLMIPTGVFAPICLSVWYPLWGGIMYIISGSLLA
                     AAAEKTSRKSLVKAKVIMSSLSLFAAISGIILSIMDILNITVSHFLKMERLELIKTPK
                     LYVDIYNCEPSNSSEKNSPSTQYCNSVQSVFLGILSVMLISAFFQKLVTAGVVENEWK
                     RVCSRPKSNVVLLSAGEKKEQTIKMKEEIIELSGVSSQPKNEEEIEIIPVQEEEEEEA
                     EINFPAPPQEQESLPVENEISP"
     exon            269..388
                     /gene="Ms4a1"
                     /gene_synonym="Cd20"
                     /inference="alignment:Splign:2.1.0"
     exon            389..448
                     /gene="Ms4a1"
                     /gene_synonym="Cd20"
                     /inference="alignment:Splign:2.1.0"
     exon            449..685
                     /gene="Ms4a1"
                     /gene_synonym="Cd20"
                     /inference="alignment:Splign:2.1.0"
     exon            686..787
                     /gene="Ms4a1"
                     /gene_synonym="Cd20"
                     /inference="alignment:Splign:2.1.0"
     exon            788..1560
                     /gene="Ms4a1"
                     /gene_synonym="Cd20"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actcatcttc aagaacttga gatagaagag gccagctgat ctcagcagtg aacagctaaa
       61 ttggtccttg agccttcaag cctcggagac ccaggggttt gaaaatagaa tgacaacacc
      121 cagaaattca gtgagtggac ctttcccaac agagcctaca aaaggacccc tcgccatgca
      181 acctgctcaa aaagtaatcc ccagaagacc atcttcactg gtgggcccca cacaaagctt
      241 cttcatgagg gaatcaaagg ctttgggggc tgtccagatc atgaatggcc tcttccacat
      301 ttccctgggg ggactgctga tgatccccac aggagttttt gcacccatct gtttgagtgt
      361 atggtaccct ctgtggggag gcattatgta catcatttca ggatcactcc tggcagctgc
      421 agcagagaaa acctccagga agagtttggt caaagcgaaa gtgataatga gctctctaag
      481 cctctttgct gccatttctg gaataattct ttcaatcatg gacatactta acattacagt
      541 ttctcatttt ttaaaaatgg agagactgga actgattaaa actcccaagc tatatgttga
      601 tatctacaac tgtgagccat ccaattcctc agagaaaaac tccccatcta cacagtactg
      661 taacagcgtg cagtctgtgt tcttgggcat tctgtcggtg atgctgatct ctgccttctt
      721 ccagaagctc gtgacagccg gtgttgtaga gaatgagtgg aaaagagtgt gctccaggcc
      781 caaatctaat gtggttctgc tgtcagctgg agaaaaaaaa gagcagacaa ttaaaatgaa
      841 agaagaaatc attgagctaa gtggagtatc ttcccaacca aagaatgaag aggaaattga
      901 aattattcca gtgcaggagg aagaagaaga agaagcagaa ataaacttcc cagcacctcc
      961 ccaagagcag gaatccttgc cagtggaaaa tgagatctct ccttaagctc ttttttaata
     1021 agcattattg tttagagagc ttccaagaca catagttaca ctcatctctt gtggccttcc
     1081 acaatctgtt ctccatattt ccacagctta cccttgcata gagaagccac atctagctct
     1141 cgttcacatt tgaagaatgc agtgattata aaggactgcc ttgtttcttg cttagggaac
     1201 tttacattgg cagaaatgct gaagaattct cattcacctt ttccttggat gggtgtctca
     1261 gtagtggtaa tgctttttct ccatttcctc catcagcagt tacagcagag ggaaaagaca
     1321 cacgactctt ccgttcatct ctgaactctc tgactccttc taaattttta gtggagtccc
     1381 ttttgcatta ttgttttaag gaaaataaca ataataataa tgagaggaaa tgagctgcct
     1441 atatgcctgt ggggaaggca caaaatgtga cctgttcttc aagcttctgt atcccacttg
     1501 ggaagctgca aaaggcttat tcctaagcct gtctgtacaa aaagcatagc ttacacataa
//
