LOCUS       NM_001399076            2453 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus MRT4 homolog, ribosome maturation factor (Mrto4),
            transcript variant 1, mRNA.
ACCESSION   NM_001399076 XM_006239178
VERSION     NM_001399076.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2453)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   2  (bases 1 to 2453)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Jan 4, 2022 this sequence version replaced XM_006239178.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC168898.1, SRR26360176.638450.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760434 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-315               JAXUCZ010000005.1  156891424-156891738 c
            316-374             JAXUCZ010000005.1  156889256-156889314 c
            375-478             JAXUCZ010000005.1  156888483-156888586 c
            479-560             JAXUCZ010000005.1  156887807-156887888 c
            561-628             JAXUCZ010000005.1  156887480-156887547 c
            629-780             JAXUCZ010000005.1  156887086-156887237 c
            781-857             JAXUCZ010000005.1  156886693-156886769 c
            858-2453            JAXUCZ010000005.1  156884985-156886580 c
FEATURES             Location/Qualifiers
     source          1..2453
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..2453
                     /gene="Mrto4"
                     /gene_synonym="RGD1311709"
                     /note="MRT4 homolog, ribosome maturation factor"
                     /db_xref="GeneID:298586"
                     /db_xref="RGD:1311709"
     exon            1..315
                     /gene="Mrto4"
                     /gene_synonym="RGD1311709"
                     /inference="alignment:Splign:2.1.0"
     CDS             288..1010
                     /gene="Mrto4"
                     /gene_synonym="RGD1311709"
                     /note="isoform 1 is encoded by transcript variant 1; MRT4,
                     mRNA turnover 4, homolog; mRNA turnover protein 4 homolog;
                     60S acidic ribosomal protein PO; mRNA turnover 4 homolog;
                     mRNA turnover 4, ribosome maturation factor"
                     /codon_start=1
                     /product="mRNA turnover protein 4 homolog isoform 1"
                     /protein_id="NP_001386005.1"
                     /db_xref="GeneID:298586"
                     /db_xref="RGD:1311709"
                     /translation="MPKSKRDKKVSLTKTAKKGLELKQNLIEELRKCVDTYKYLFIFS
                     VANMRNSKLKDIRNAWKHSRMFFGKNKVMMVALGRSPSDEYKDNLHQVSKKLRGEVGL
                     LFTNRTKEEVNEWFTKYTEMDFARAGNKATLTVSLDPGPLKQFPHSMEPQLRQLGLPT
                     ALKKGVVTLLSDYEVCKEGDVLTPEQARVLKLFGYEMAEFKVTIKYMWDAQSGRFQQM
                     DDDLPESAPESEGESEEEEDDS"
     exon            316..374
                     /gene="Mrto4"
                     /gene_synonym="RGD1311709"
                     /inference="alignment:Splign:2.1.0"
     exon            375..478
                     /gene="Mrto4"
                     /gene_synonym="RGD1311709"
                     /inference="alignment:Splign:2.1.0"
     exon            479..560
                     /gene="Mrto4"
                     /gene_synonym="RGD1311709"
                     /inference="alignment:Splign:2.1.0"
     exon            561..628
                     /gene="Mrto4"
                     /gene_synonym="RGD1311709"
                     /inference="alignment:Splign:2.1.0"
     exon            629..780
                     /gene="Mrto4"
                     /gene_synonym="RGD1311709"
                     /inference="alignment:Splign:2.1.0"
     exon            781..857
                     /gene="Mrto4"
                     /gene_synonym="RGD1311709"
                     /inference="alignment:Splign:2.1.0"
     exon            858..2453
                     /gene="Mrto4"
                     /gene_synonym="RGD1311709"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cctccggaga gccatagaga ggaaccggtt cgcgagggcc ttggtgaagt gttccggatt
       61 cggaagccgc ggcgatcagg ggggccgaag ggactggaag gctctggaac ctgggcagag
      121 aagtggcctt ccaggcccta ggcagaacgc aggcagggaa gagagggccc accacacttc
      181 gggtcaggca cacgagagag gcagccccga gcgccgcccc acaagcctct gcggcacccg
      241 ggtcctgacg ggccgccggg tcttccgccg cacgtgcctt tagcgcgatg cccaaatcca
      301 agcgagacaa gaaagtttcc ttaacaaaaa ctgccaagaa aggcttggaa ctgaagcaga
      361 acctgataga agagcttcgg aaatgcgtgg acacctacaa gtacctcttc atcttctctg
      421 tggccaacat gaggaacagc aagctgaagg acatccggaa tgcctggaag cacagccgga
      481 tgttctttgg caaaaacaag gtgatgatgg tggccttggg tcgaagcccg tctgatgaat
      541 acaaagacaa cctacatcag gtcagcaaga agttgagagg tgaagttggg ctccttttta
      601 ccaaccgcac gaaggaggag gtgaatgagt ggttcacaaa gtatacagaa atggattttg
      661 ctcgagcggg gaacaaagca actttaactg tgagcctgga tccagggccg ctgaaacagt
      721 tccctcattc catggagcca cagctgaggc agctgggtct gcccactgcc ctcaagaaag
      781 gtgtggtgac cttgctgtct gactatgaag tgtgcaagga gggtgacgtg ctgaccccag
      841 agcaggcccg tgtcctgaag ctgtttgggt atgagatggc cgaattcaaa gtgaccatca
      901 aatacatgtg ggatgcccag tcagggagat tccagcagat ggacgatgac cttcccgaga
      961 gcgcgcctga gtctgagggg gagtctgagg aggaggagga cgacagctga ctctgggaac
     1021 cagaaccaag gccttccagc aagtacttca tctccactgg acgcccccag gactgctgtc
     1081 gccccctaga gggagcggct ggtttttttg ctatggataa agacaaggga ggtgctgggc
     1141 agtgactttg tttctataga gaataaaatt ttgtctgcag ggtgctccct gtagacagca
     1201 gagactcttt ataaaggcct tcggctgtgc tccagcctag tcgggctagg gctgggtggg
     1261 ccagcactgc agatggctga gagcacgcct ggatttgggt gtctttgtcc gtttgcttgc
     1321 agtgggtttg ctgaggaaag ttaattctct ggaagcttga tcacttaaaa cataaataag
     1381 cacacagata cgtgcaagcc gggggtaaaa tatgaggaac acaggcttgc cacagggcgg
     1441 tggaggggat tgggagcaag tggagtttga gtcaggttct cactgaagca cagactggtc
     1501 ttgatcttac agtagtttct ggcctctgcc cctcaagtgc taccacactt ggctgactag
     1561 tagtgattag tagctgtgtg ctgtgcgagt cagtggtaag gcatcataaa ccatgcttaa
     1621 ggccagcagg tccctccctg gcagcacaca gaaactgagg aaagttgttg gacctgtggg
     1681 tcagaaaatc ctcagagttc ctgacctcta ccctagagga gggatgtggg ggttaaacag
     1741 caacactgaa taagatgggc cttgggtctt cataatcatg cccaaaaaac ccagggcaag
     1801 ccaatatgat aatgcttgga atgccagcac ctcaggaggc tgaggtagga ttgaaagttt
     1861 gaggccaagc caggcagagg gaggccaatc tctgaattgg aggccactca tggctaaata
     1921 aagcctatct caaaaaaagt ttgataccaa tcaactataa ggctgaaaaa aggcaggctt
     1981 ggggctggag agatggctca gtggttaaga gcaccgactg ctcttccaga ggtcctgagt
     2041 tcaattccca gcaaccacat ggtggctcac aaccatctgt aatgggatct gatgcccttt
     2101 tctggtgtgt ctgaagacag ctgtagtgtt cttatatata ataaataaat cattatagga
     2161 aaaaaaaaag ggcaggcttg gttgtatgca ccagaaattg aaagctagag acaagagacc
     2221 tgataggagt tcaaggccag cctagagtat atggcatttt gtcttaaaaa gaaaaggcca
     2281 gggtggtggt ggctcacacc tttaatacca gcacttggga ggcagaattc aggacagcca
     2341 gggctacaca cagatacatt gtctcaaagg ggaaagtaag aaagacaagt gacatgtttc
     2401 agcagaccga agcacttgct gccaaatcaa ttaaaatgtt gcttagtact caa
//
