LOCUS       NM_001105771             901 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus mitochondrial ribosomal protein S34 (Mrps34),
            mRNA.
ACCESSION   NM_001105771 XM_001057977 XM_213234
VERSION     NM_001105771.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 901)
  AUTHORS   Lake,N.J., Webb,B.D., Stroud,D.A., Richman,T.R., Ruzzenente,B.,
            Compton,A.G., Mountford,H.S., Pulman,J., Zangarelli,C., Rio,M.,
            Boddaert,N., Assouline,Z., Sherpa,M.D., Schadt,E.E., Houten,S.M.,
            Byrnes,J., McCormick,E.M., Zolkipli-Cunningham,Z., Haude,K.,
            Zhang,Z., Retterer,K., Bai,R., Calvo,S.E., Mootha,V.K.,
            Christodoulou,J., Rotig,A., Filipovska,A., Cristian,I., Falk,M.J.,
            Metodiev,M.D. and Thorburn,D.R.
  TITLE     Biallelic Mutations in MRPS34 Lead to Instability of the Small
            Mitoribosomal Subunit and Leigh Syndrome
  JOURNAL   Am J Hum Genet 101 (2), 239-254 (2017)
   PUBMED   28777931
  REMARK    Erratum:[Am J Hum Genet. 2018 Apr 5;102(4):713. PMID: 29625026]
REFERENCE   2  (bases 1 to 901)
  AUTHORS   Richman,T.R., Ermer,J.A., Davies,S.M., Perks,K.L., Viola,H.M.,
            Shearwood,A.M., Hool,L.C., Rackham,O. and Filipovska,A.
  TITLE     Mutation in MRPS34 compromises protein synthesis and causes
            mitochondrial dysfunction
  JOURNAL   PLoS Genet 11 (3), e1005089 (2015)
   PUBMED   25816300
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473948.1.
            
            On or before Oct 3, 2007 this sequence version replaced
            XM_001057977.1, XM_213234.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ228234.1, FM029630.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..901
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q12"
     gene            1..901
                     /gene="Mrps34"
                     /note="mitochondrial ribosomal protein S34"
                     /db_xref="GeneID:287126"
                     /db_xref="RGD:1305623"
     exon            1..368
                     /gene="Mrps34"
                     /inference="alignment:Splign:2.1.0"
     CDS             48..704
                     /gene="Mrps34"
                     /note="28S ribosomal protein S34, mitochondrial"
                     /codon_start=1
                     /product="small ribosomal subunit protein mS34"
                     /protein_id="NP_001099241.1"
                     /db_xref="GeneID:287126"
                     /db_xref="RGD:1305623"
                     /translation="MARKKVKPRLIAELARRVRALREQRNQPRDSQLYALDYETLTRP
                     HSGRRLPVRAWADVRRESRLLQLLARLPLFGLGRLVTRKSWLWQHDEPCYWRLTRVRP
                     DYTAQNLDHGRAWGILTFKGKSEETAREIEQVMYHDWRLVPKHEEEAFTAFTGKAEDR
                     LNLVPYPPLLRAMILAERQKNGDTSVEEPLLNLERTRMRPWDYPAKQETKGRAKGTPV
                     "
     exon            369..411
                     /gene="Mrps34"
                     /inference="alignment:Splign:2.1.0"
     exon            412..901
                     /gene="Mrps34"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tggggagctg gtgaagcgca ggtttcctgt ggagtaagga caccggcatg gcgcggaaga
       61 aagtgaaacc ccggctgatc gctgagctgg cccgccgcgt gcgcgccttg cgcgagcagc
      121 ggaaccagcc gcgagactcg cagctctacg ccctagacta cgagacgctg acccggccgc
      181 actctggtcg ccggctgcca gtgcgcgcct gggccgacgt acgtcgcgag agccgccttc
      241 tacagctgct cgcccgcctc cccttgtttg gcctgggtcg tctggttacc cgcaagtcct
      301 ggctgtggca gcacgacgag ccatgctact ggcgcctcac gcgtgtgagg cctgactaca
      361 cggcgcagaa cttggaccac gggagggcct ggggtatcct gactttcaaa gggaagagtg
      421 aggaaacggc tcgggaaatc gagcaagtca tgtaccacga ttggcggttg gtacccaagc
      481 acgaggagga ggctttcact gcgttcactg ggaaagcaga ggacagattg aaccttgtcc
      541 cctacccacc tctgctgcgg gccatgatcc tcgctgagcg acagaaaaac ggggatacca
      601 gcgtcgagga gccgctcctg aacctggaga ggactcgaat gcgcccctgg gactaccctg
      661 caaaacagga gactaaaggg agagccaagg gcaccccagt ctaactgcca ggattggcag
      721 agaggtcctg tgagtcattt gatggacaag tgtctttgac tgtgtcagaa tctccccttt
      781 ggtggggaga ccctaaagcc ttgacacatc tgccaatgaa taatggggca gatgacagat
      841 tgtgattttc aggcggcccc tcgccgattc ctccgtctgg aaataaactc ccgaaatggc
      901 c
//
