LOCUS       NM_001199192            1345 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus mitochondrial ribosomal protein S27 (Mrps27),
            transcript variant 1, mRNA.
ACCESSION   NM_001199192
VERSION     NM_001199192.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1345)
  AUTHORS   Pu,M., Wang,J., Huang,Q., Zhao,G., Xia,C., Shang,R., Zhang,Z.,
            Bian,Z., Yang,X. and Tao,K.
  TITLE     High MRPS23 expression contributes to hepatocellular carcinoma
            proliferation and indicates poor survival outcomes
  JOURNAL   Tumour Biol 39 (7), 1010428317709127 (2017)
   PUBMED   28714366
REFERENCE   2  (bases 1 to 1345)
  AUTHORS   Davies,S.M., Lopez Sanchez,M.I., Narsai,R., Shearwood,A.M.,
            Razif,M.F., Small,I.D., Whelan,J., Rackham,O. and Filipovska,A.
  TITLE     MRPS27 is a pentatricopeptide repeat domain protein required for
            the translation of mitochondrially encoded proteins
  JOURNAL   FEBS Lett 586 (20), 3555-3561 (2012)
   PUBMED   22841715
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DN934981.1, FM121157.1, CB576151.1 and JAXUCZ010000002.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643295.7764.1,
                                           SRR26643292.7367.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-89                DN934981.1         27-115
            90-664              FM121157.1         62-636
            665-1118            CB576151.1         192-645
            1119-1345           JAXUCZ010000002.1  32541956-32542182
FEATURES             Location/Qualifiers
     source          1..1345
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q12"
     gene            1..1345
                     /gene="Mrps27"
                     /note="mitochondrial ribosomal protein S27"
                     /db_xref="GeneID:361883"
                     /db_xref="RGD:1311829"
     exon            1..105
                     /gene="Mrps27"
                     /inference="alignment:Splign:2.1.0"
     CDS             33..1280
                     /gene="Mrps27"
                     /note="isoform 1 is encoded by transcript variant 1; 28S
                     ribosomal protein S27, mitochondrial; small ribosomal
                     subunit protein mS27"
                     /codon_start=1
                     /product="small ribosomal subunit protein mS27 isoform 1"
                     /protein_id="NP_001186121.1"
                     /db_xref="GeneID:361883"
                     /db_xref="RGD:1311829"
                     /translation="MAAPMVRCGMLLARGIAASRLSLAGKRCLLSAAYVDSHQWEARE
                     KEQCHLADLASLMDKAYERKLPVSSLSISRFVDNISSREDIDSAEYYLYKFRHSPNCW
                     YLRDWTIHTWIRQCLKYGAPDKALYTLVNKVQYGIFPDNFTFNLLMDYFIKKENYKDA
                     LSVVFEIMKQEAFEVPSTQFLSLYVLYHCLAEKTDLTWEEERDFGASLLLPGLKQRNT
                     VGLSSQLYGYALLGKVELQCGLRAVYHGMPLIWTPGYLDRALQVMERVASSPEDVKLC
                     REVLDVLDGVLKVVMSPDGQASETQPQEGEDSLGSANLVEQLDTEEPEQSRLPQYLER
                     FQASRSKLQELNRVESESLLTLTTQLVKENLSACEAQDLATYEQKLREWHQERMQLVQ
                     REQEQREKAKQEYQSLSAVENAA"
     exon            106..183
                     /gene="Mrps27"
                     /inference="alignment:Splign:2.1.0"
     exon            184..254
                     /gene="Mrps27"
                     /inference="alignment:Splign:2.1.0"
     exon            255..313
                     /gene="Mrps27"
                     /inference="alignment:Splign:2.1.0"
     exon            314..428
                     /gene="Mrps27"
                     /inference="alignment:Splign:2.1.0"
     exon            429..507
                     /gene="Mrps27"
                     /inference="alignment:Splign:2.1.0"
     exon            508..623
                     /gene="Mrps27"
                     /inference="alignment:Splign:2.1.0"
     exon            624..726
                     /gene="Mrps27"
                     /inference="alignment:Splign:2.1.0"
     exon            727..869
                     /gene="Mrps27"
                     /inference="alignment:Splign:2.1.0"
     exon            870..1040
                     /gene="Mrps27"
                     /inference="alignment:Splign:2.1.0"
     exon            1041..1345
                     /gene="Mrps27"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccggggcggc ggtccatttg gtacgctcca agatggcggc ccccatggtg cggtgtggga
       61 tgctcctggc tcggggaata gctgcgtctc gcctttcctt ggcaggtaaa agatgcctgc
      121 tctccgcagc atacgtggac agccaccagt gggaagcaag agagaaggag caatgccatc
      181 tggctgatct tgcatcctta atggacaaag catatgaaag gaagttgcct gttagttctt
      241 tatcaatatc tcggtttgtg gacaacattt catctcgaga agatatagac tctgccgagt
      301 actatcttta caaatttcga cacagtccca actgctggta cttgagagac tggaccatcc
      361 acacgtggat tagacagtgt ctgaaatacg gagcaccaga caaagccttg tatacacttg
      421 ttaataaggt tcagtatgga atttttccag ataactttac attcaactta ctgatggatt
      481 atttcataaa gaaagaaaat tataaagatg ctttgtctgt ggtttttgag atcatgaagc
      541 aagaagcctt tgaagtgcca tccacccagt tcctctccct ctatgtttta taccattgcc
      601 tagcagagaa gacagacctc acatgggaag aagaaagaga cttcggtgcg tccctattgc
      661 ttccaggcct aaaacaaagg aacacagtgg gcttgagttc ccagctgtat ggctatgcac
      721 ttctcgggaa ggtagaactg cagtgtgggc tgcgggctgt ctaccacggc atgcctctga
      781 tttggacacc aggctacctc gacagagccc ttcaagtgat ggagagggtg gcctcctccc
      841 ctgaagatgt caagctgtgt agagaagtgc tcgatgtgct ggacggagtc ctgaaggtgg
      901 tgatgtctcc agacggccag gcttcagaga cacagcccca ggagggcgaa gacagcttgg
      961 gctcagcaaa cctggtggag cagctggaca ctgaggaacc agagcagtcc aggctgcccc
     1021 agtacctgga gcggtttcag gcctctcggt ccaaactaca ggagttgaac agagttgagt
     1081 cggaaagcct tctgactctg accacccagc ttgtaaaaga aaacctctcc gcctgtgaag
     1141 cccaggacct ggccacttac gagcagaaac ttcgagagtg gcaccaggag cggatgcagt
     1201 tggtccagag ggaacaggaa cagagggaga aggccaagca ggagtaccag tcgctgagtg
     1261 cagtggagaa tgcagcctga agtgccccag gccaccccag ccttctgcca ggatgggact
     1321 cggcctccgc ctccagctct ttctt
//
