LOCUS       NM_001106852            1647 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus mitochondrial ribosomal protein L3 (Mrpl3), mRNA.
ACCESSION   NM_001106852 XM_001072824 XM_217239
VERSION     NM_001106852.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1647)
  AUTHORS   Brown,A., Rathore,S., Kimanius,D., Aibara,S., Bai,X.C., Rorbach,J.,
            Amunts,A. and Ramakrishnan,V.
  TITLE     Structures of the human mitochondrial ribosome in native states of
            assembly
  JOURNAL   Nat Struct Mol Biol 24 (10), 866-869 (2017)
   PUBMED   28892042
REFERENCE   2  (bases 1 to 1647)
  AUTHORS   Brown,A., Amunts,A., Bai,X.C., Sugimoto,Y., Edwards,P.C.,
            Murshudov,G., Scheres,S.H.W. and Ramakrishnan,V.
  TITLE     Structure of the large ribosomal subunit from human mitochondria
  JOURNAL   Science 346 (6210), 718-722 (2014)
   PUBMED   25278503
REFERENCE   3  (bases 1 to 1647)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   4  (bases 1 to 1647)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   5  (bases 1 to 1647)
  AUTHORS   Richter,R., Rorbach,J., Pajak,A., Smith,P.M., Wessels,H.J.,
            Huynen,M.A., Smeitink,J.A., Lightowlers,R.N. and
            Chrzanowska-Lightowlers,Z.M.
  TITLE     A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into
            the human mitochondrial ribosome
  JOURNAL   EMBO J 29 (6), 1116-1125 (2010)
   PUBMED   20186120
REFERENCE   6  (bases 1 to 1647)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   7  (bases 1 to 1647)
  AUTHORS   Ou,J.H., Yen,T.S., Wang,Y.F., Kam,W.K. and Rutter,W.J.
  TITLE     Cloning and characterization of a human ribosomal protein gene with
            enhanced expression in fetal and neoplastic cells
  JOURNAL   Nucleic Acids Res 15 (21), 8919-8934 (1987)
   PUBMED   2891103
  REMARK    Erratum:[Nucleic Acids Res 1988 May 11;16(9):4196]
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473954.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001072824.1, XM_217239.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1647
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q32"
     gene            1..1647
                     /gene="Mrpl3"
                     /note="mitochondrial ribosomal protein L3"
                     /db_xref="GeneID:300974"
                     /db_xref="RGD:1306391"
     exon            1..277
                     /gene="Mrpl3"
                     /inference="alignment:Splign:2.1.0"
     CDS             186..1232
                     /gene="Mrpl3"
                     /note="39S ribosomal protein L3, mitochondrial; L3mt;
                     MRP-L3"
                     /codon_start=1
                     /product="large ribosomal subunit protein uL3m"
                     /protein_id="NP_001100322.1"
                     /db_xref="GeneID:300974"
                     /db_xref="RGD:1306391"
                     /translation="MPGWRLLAQAGAQVLGCGAGGLGAAPGLGSRKNILFVVRNLHSK
                     SSTWWDEHLSEENVSFVKQLVSDENKAQLTSKLNPLKDEPWPLHPWEPGSSRVGLIAL
                     KLGMMPLWTKDGQKHAVTLLQVQDCHVLKYTPKEDHNGKTAALTVGGKTGSRLYKPNS
                     ILEFYRDLGLPPKQTIKIFHVTDNAVIKPGTPLYAAHFRPGQYVDVTAKTIGKGFQGV
                     MKRWGFKGQPASHGQTKTHRRPGAISTGDIARVWPGTKMPGQMGNQNRTVYGLKVWRV
                     NTKHNIIYVNGSVPGHRNCLVKIKDSTLPAYKDLCKSLPFPTYFPDGDEEELPEDLYD
                     ESVWQPSEPSITFA"
     exon            278..462
                     /gene="Mrpl3"
                     /inference="alignment:Splign:2.1.0"
     exon            463..554
                     /gene="Mrpl3"
                     /inference="alignment:Splign:2.1.0"
     exon            555..653
                     /gene="Mrpl3"
                     /inference="alignment:Splign:2.1.0"
     exon            654..753
                     /gene="Mrpl3"
                     /inference="alignment:Splign:2.1.0"
     exon            754..814
                     /gene="Mrpl3"
                     /inference="alignment:Splign:2.1.0"
     exon            815..923
                     /gene="Mrpl3"
                     /inference="alignment:Splign:2.1.0"
     exon            924..1001
                     /gene="Mrpl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1002..1079
                     /gene="Mrpl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1080..1647
                     /gene="Mrpl3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagaaacgga ccggaagtgg ctcagctgtg cttttcctcc gctgagggca ttggcggaca
       61 aaccgtgtga ctgctgtcct ggtgctactg cgaactcgtg gtgtttgtgt tggggactta
      121 ctgaaagttc cgcggcggcg gcgcggcggg aggtgtcgcg agccgagcac tgcccggcca
      181 cttccatgcc gggttggagg ctgctggcgc aagctggcgc ccaagtgctg ggttgtggcg
      241 ccggaggcct aggtgctgcc ccaggcttag ggagtagaaa gaacatcttg ttcgttgtta
      301 gaaatctgca cagcaagagt agtacttggt gggatgagca tctgtctgaa gaaaatgtct
      361 cgtttgttaa acagctggtc tccgatgaaa ataaagccca gctgacaagt aaactgaacc
      421 ccttgaagga cgaaccatgg cctttgcatc cctgggaacc aggttcttcc agagttggcc
      481 ttatcgccct gaagctgggt atgatgcctt tatggaccaa ggatggtcaa aagcatgcag
      541 tcaccttact tcaggtacaa gactgtcatg tgttaaagta cactcccaag gaagaccata
      601 atggaaaaac agcggcccta acagtggggg ggaaaaccgg gtcacgcctg tataaaccca
      661 actctatatt ggaattttac cgagatcttg gattgccacc aaaacagaca attaaaatct
      721 ttcatgtaac agataatgct gtaattaagc cagggactcc tctttatgca gctcactttc
      781 gccccggaca gtatgtggat gtcacagcca aaactattgg taaaggtttt cagggcgtca
      841 tgaaaagatg gggatttaaa ggccaacctg cttctcacgg tcaaacaaag acccacagga
      901 gacctggcgc catctcaact ggggatattg ccagagtctg gcctggaact aaaatgcccg
      961 ggcaaatggg aaaccaaaac aggacagtgt atgggctgaa ggtgtggaga gtgaacacca
     1021 agcacaatat aatctatgtc aatggctctg tgcctggaca tagaaattgc ttagtgaaga
     1081 tcaaggactc tacgctgcct gcatacaagg atctctgtaa gagcctgccg ttccctacct
     1141 actttcctga tggagacgaa gaagaacttc cagaagatct gtacgatgag agcgtgtggc
     1201 agcccagcga accttccatc acctttgcct gatgcgctgg tgctgcaggc ctctgtgctc
     1261 cgcgtacttt ggtgaccaga tcagtaatag aaccaggagt gggatgtcgt tccctgtgct
     1321 tagtcatgag agcaagctcc tgtgtccacc aagggcacaa gtgagccact tggcccctct
     1381 tcagtctgat tagcaaggtt actgcattaa cagtcacata gactgggttt gttaacattg
     1441 acagtttgta aagaacaagc tgcctgccgt ttgtggtgtc attctttaga cacatttccc
     1501 agtcttgttt tggtttatag ttttattaaa gatttatctc tcttaatatc tggttgtgaa
     1561 acagaacctg gggaactaca ttgcggtgtg atgggtaaaa gaatccattt ctttagaaac
     1621 acaacattca tttagagttt acaagct
//
